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Consolidated Statements of Cash Flows (USD $)
12 Months Ended
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2010
Operating activities:      
Net income (loss) $ 1,652,181 $ (23,325,116) $ (13,032,942)
Adjustments to reconcile net income (loss) to net cash flows from operating activities      
Depreciation 465,929 444,527 422,127
Amortization of Intangible Assets 1,020,878 890,980 844,216
Derivative loss (gain) 5,594,152 (3,463,453) (3,126,771)
Stock-based compensation expense 1,619,269 1,226,724 1,376,467
Intangible license impairment     243,648
Warrants received in settlement     (382,800)
Changes in assets and liabilities:      
Accounts receivable (419,680) 530,544 635,526
Prepaid expenses and other assets 3,822 6,226 51,866
Accounts payable and accrued expenses 5,567,962 407,441 809,517
Income Taxes Payable 129,120   (312,128)
Deferred Revenue (3,446,309) 7,133 788,977
Net cash flows from operating activities 12,187,324 (23,274,994) (11,682,297)
Investing activities:      
Purchase of equipment (38,550) (286,973) (103,985)
Purchase of intangible assets (1,050,000)   (1,000,000)
Net cash flows from investing activities (1,088,550) (286,973) (1,103,985)
Financing activities:      
Proceeds from sales of securities 38,373,014 13,996,773 9,747,500
Proceeds from exercise of stock options 2,054,100 349,676 97,882
Proceeds from exercise of common stock warrants 921,019 1,749,259  
(Repayment of) proceeds from related party advances, net (7,805) 7,805 (2,723,844)
Net cash flows from financing activities 41,340,328 16,103,513 7,121,538
Net change in cash and cash equivalents 52,439,102 (7,458,454) (5,664,744)
Cash and cash equivalents at beginning of year 10,750,205 18,208,659 23,873,403
Cash and cash equivalents at end of year $ 63,189,307 $ 10,750,205 $ 18,208,659