Income Taxes (Details 1) (USD $)	Dec. 31, 2012	Dec. 31, 2011
Significant components of deferred tax assets and liabilities
Deferred revenue	$ 4,010,493	$ 5,291,485
Basis difference in equipment	(926,735)	(1,008,114)
Basis difference in intangibles	(618,403)	(1,090,516)
Accrued liabilities and other	263,364	686,809
Loss on extinguishment
R&D Credit	8,720,314	5,591,029
Stock options	1,557,756	1,606,254
Derivative
Net operating loss carry-forward (NOL)	16,575,544	19,055,559
Gross, Deferred Tax Assets	29,582,333	30,132,506
Less: valuation allowance	(29,582,333)	(30,132,506)
Net of Valuation Allowance