Consolidated Statements of Stockholders' Equity (USD $)	Total	Preferred Stock Series A	Common Stock	Additional Paid-In Capital	Treasury Stock	Accumulated Deficit	CDC Warrant	CDC Warrant Common Stock	CDC Warrant Additional Paid-In Capital	Registered Direct	Registered Direct Common Stock	Registered Direct Additional Paid-In Capital	Private Placement	Private Placement Preferred Stock Series A	Private Placement Common Stock	Private Placement Additional Paid-In Capital
Beginning Balance at Dec. 31, 2009	$ 14,458,299		$ 21,182	$ 73,697,818	$ (47,183)	$ (59,213,518)
Beginning Balance, Shares at Dec. 31, 2009			21,181,854
Stock-based compensation	1,376,467			1,376,467
Stock option exercise, shares	31,733		31,733
Stock option exercise	97,882		32	97,850
Stock offering, net share											2,824,858
Stock offering, net										9,747,500	2,825	9,744,675
Warrants related to equity financing	(2,860,876)			(2,860,876)
Net income (loss)	(13,032,942)					(13,032,942)
Ending Balance at Dec. 31, 2010	9,786,330		24,039	82,055,934	(47,183)	(72,246,460)
Ending Balance, Shares at Dec. 31, 2010			24,038,445
Stock-based compensation	1,226,724			1,226,724
Stock option exercise, shares	129,888		129,888
Stock option exercise	349,676		130	349,546
Warrants exercises							1,749,259	601	1,748,658
Warrants exercises, shares								601,120
CDC warrant derivative reclassified to equity	336,747			336,747
Stock offering, net share															4,807,693
Stock offering, net													13,996,773		4,808	13,991,965
Net income (loss)	(23,325,116)					(23,325,116)
Ending Balance at Dec. 31, 2011	4,120,393		29,578	99,709,574	(47,183)	(95,571,576)
Ending Balance, Shares at Dec. 31, 2011			29,577,146
Stock-based compensation	1,619,269			1,619,269
Stock option exercise, shares	789,305		789,305
Stock option exercise	2,054,100		789	2,053,311
Warrants exercises	921,019		282	920,737
Warrants exercises, shares			281,865
Warrant derivative liability reclassified to equity	1,037,237			1,037,237
Stock offering, net share														2,709,300	6,791,887
Stock offering, net													38,373,014	2,709	6,792	38,363,513
Restricted stock awards			58	(58)
Restricted stock awards, shares			57,500
Net income (loss)	1,652,181					1,652,181
Ending Balance at Dec. 31, 2012	$ 49,777,213	$ 2,709	$ 37,499	$ 143,703,583	$ (47,183)	$ (93,919,395)
Ending Balance, Shares at Dec. 31, 2012		2,709,300	37,497,703