Nature of Business and Summary of Significant Accounting Policies (Details Textual) (USD $)	1 Months Ended			12 Months Ended
	May 31, 2012	Jan. 31, 2012	Jun. 30, 2010	Dec. 31, 2012 Agreements	Dec. 31, 2011	Dec. 31, 2010
Nature of Business and Summary of Significant Accounting Policies (Additional Textual) [Abstract]
Common Stock, par value				$ 0.001	$ 0.001
FDIC insurance coverage amount				$ 250,000
Net deposit amount exceeds specified amount under FDIC				24,200,000
Impairment charges recognized on finite lived intangibles assets			200,000	0	0	200,000
Goodwill impairment charges				0	0	0
Outstanding stock options and warrants				5,509,072	7,847,052	9,585,460
Deferred amount earned out of total deferred revenue		5,200,000
Revenue associated with intellectual property milestone	15,000,000
Trade accounts receivable				83.00%	92.00%
Original ratcheting strike price				$ 0.0467
Revised ratcheting strike price				$ 0.0312
Revenue recognized from delivery of license rights to Endo		15,600,000
Non-refundable up-front license payment	15,000,000	30,000,000
Recognized Deferred revenue related to research and development services rendered		14,400,000
License and Development agreements				2
Maximum [Member]
Nature of Business and Summary of Significant Accounting Policies (Textual) [Abstract]
Estimated useful lives of equipment				10 years
Minimum [Member]
Nature of Business and Summary of Significant Accounting Policies (Textual) [Abstract]
Estimated useful lives of equipment				5 years
Impairment of Intangible Assets [Member]
Nature of Business and Summary of Significant Accounting Policies (Textual) [Abstract]
Amortization expense on other intangible assets				$ 1,000,000	$ 900,000	$ 800,000