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Nature of Business and Summary of Significant Accounting Policies (Tables)
12 Months Ended
Dec. 31, 2012
Nature of Business and Summary of Significant Accounting Policies [Abstract]  
Intangible assets with finite useful lives, amortized over estimated useful lives

Intangible assets with finite useful lives are amortized over the estimated useful lives as follows:

 

         
    Estimated
Useful  Lives
 

Licenses

    14 years  

U.S. Product right

    10-12 years  

EU Product rights

    11 years  
Estimated aggregate future amortization expenses for other intangible assets

Estimated aggregate future amortization expenses for other intangible assets for each of the next five years and thereafter are as follows:

 

         

Years ending December 31,

     

2013

  $ 1,020,878  

2014

    1,020,878  

2015

    1,020,878  

2016

    1,020,878  

2017

    1,020,878  

Thereafter

    1,075,094  
   

 

 

 
   
    $ 6,179,484  
   

 

 

 
Reconciliation of the numerators and denominators of the basic and diluted earnings per common share computations

The following is a reconciliation of the numerators and denominators of the basic and diluted earnings per common share computations for the years ended December 31, 2012, 2011 and 2010.

 

                         
    December 31,  
    2012     2011     2010  

Basic:

                       

Net income (loss) attributable to common stockholders

  $ 1,652,181     $ (23,325,116   $ (13,032,942

Weighted average common shares outstanding

    30,546,581       28,322,477       23,150,975  
   

 

 

   

 

 

   

 

 

 

Basic earnings per common share

  $ 0.05     $ (0.82   $ (0.56
   

 

 

   

 

 

   

 

 

 
       

Diluted:

                       

Effect of dilutive securities:

                       

Net income (loss) attributable to common stockholders

    1,652,181       (23,325,116     (13,032,942

Adjustments to Income for Dilutive options and warrants

    —         —         —    
   

 

 

   

 

 

   

 

 

 
      1,652,181       (23,325,116     (13,032,942

Weighted average common shares outstanding

    30,546,581       28,322,477       23,150,975  

Effect of Dilutive options and warrants

    142,654       —         —    
   

 

 

   

 

 

   

 

 

 

Diluted weighted average common shares outstanding

    30,689,235       28,322,477       23,150,975  
   

 

 

   

 

 

   

 

 

 

Diluted earnings per common share

  $ 0.05     ($ 0.82   ($ 0.56
   

 

 

   

 

 

   

 

 

 
Summary of total outstanding options and warrants

The following is the total outstanding options and warrants for the years ended December 31, 2012, 2011 and 2010, respectively.

 

                         
    2012     2011     2010  

Options and warrants to purchase Common Stock

    6,289,355       7,847,052       9,585,460  
Black Scholes options-pricing model, assumptions

In applying the Black Scholes options-pricing model, assumptions are as follows:

 

             
    2012   2011   2010

Expected price volatility

  81.96%-83.69%   69.05%-77.75%   73.41%-79.02%

Risk-free interest rate

  0.62%-1.02%   0.90%-1.99%   1.17%-2.36%

Weighted average expected life in years

  5-6 years   5-6 years   5-6 years

Dividend yield

  —     —     —  
Summary of assets and liabilities measured at fair value on a recurring basis

The following table summarizes assets and liabilities measured at fair value on a recurring basis at December 31, 2012 and December 31, 2011, respectively:

 

                                                                 
    2012     2011  

Fair Value Measurements Using:

  Level 1     Level 2     Level 3     Total     Level 1     Level 2     Level 3     Total  

Assets

                                                               

Derivative asset (warrant)

  $ —       $ 50,300     $ —       $ 50,300     $ —       $ 388,540     $ —       $ 388,540  

Liabilities

                                                               

Derivative liabilities

  $ —       $ 4,497,977     $ —       $ 4,497,977     $ —       $ 279,302     $ —       $ 279,302  
Reconciliation of beginning and ending balances of assets and liabilities measured at fair value using significant observable inputs

The table below provides a reconciliation of the beginning and ending balances for the assets and liabilities measured at fair value using significant observable inputs (Level 2). The table reflects net gains and losses for all financial assets and liabilities categorized as Level 2 as of December 31, 2011 and 2012.

Fair Value Measurements Using Significant Observable Inputs (Level 2)

 

                 
    Value of
Warrants
    Number of
Warrants
 

Assets:

               

Warrant asset as of January 1, 2011

  $ 1,299,031       2,000,000  

Decrease in fair value of warrants

    (910,491     —    
   

 

 

   

 

 

 

Warrant asset as of December 31, 2011

  $ 388,540       2,000,000  
   

 

 

   

 

 

 

Decrease in fair value of warrants

    (338,240        
   

 

 

   

 

 

 

Warrant asset as of December 31, 2012

  $ 50,300       2,000,000  
   

 

 

   

 

 

 

Liabilities:

               

Warrant liability as of January 1, 2011

  $ 4,989,994       4,322,421  

Increase of fair value of warrants due to ratcheting strike price down to $3.12 from $4.67 as a result of private placement offering

    460,452       —    

Decrease due to exercise of CDC warrants

    (336,747     (601,120

Expiration of warrants

    —         (475,000

Decrease in fair value of warrants

    (4,834,397     —    
   

 

 

   

 

 

 

Warrant liability as of December 31, 2011

  $ 279,302       3,246,301  
   

 

 

   

 

 

 

Decrease due to exercise of warrants

    (1,037,237     (236,865

Expiration of warrants

    —         (1,000,000 )

Increase in fair value of warrants

    5,255,912       —    
   

 

 

   

 

 

 

Warrant liability as of December 31, 2012

  $ 4,497,977       2,009,436