X0304 4 2012-02-09 0 0001103021 BIODELIVERY SCIENCES INTERNATIONAL INC BDSI 0001301715 Sirgo Mark A C/O BIODELIVERY SCIENCES INTL, INC. 801 CORPORATE CENTER DRIVE, SUITE 210 RALEIGH NC 27607 1 1 0 0 President and CEO Stock Option 1.78 2012-02-09 4 A 0 70366 A 2022-02-09 Common Stock 70366 70366 D Stock Option 1.96 2012-02-15 4 A 0 33026 A 2012-02-15 2022-02-15 Common Stock 33026 33026 D One third of the options granted herein will vest and be exercisable on each of the following dates, February 09, 2013, February 09, 2014 and February 09, 2015, subject to the condition that the reporting person is employed by the Issuer on each of the respective dates. Not applicable. Such options were granted by Issuer's Board of Directors as compensation for serving on the Board of Directors. /s/ Mark A. Sirgo 2012-02-21