X0202 4 2008-03-12 0 0001103021 BIODELIVERY SCIENCES INTERNATIONAL INC BDSI 0001301715 Sirgo Mark A 801 CORPORATE CENTER DRIVE SUITE 210 RALEIGH NC 27607 1 1 0 0 President and CEO Common Stock 2008-03-12 4 P 0 5000 2.42 A 829443 D Common Stock 2008-03-13 4 P 0 1000 2.36 A 830443 D Common Stock 1800 I Via Family Stock Option (right to buy) 6.63 2017-04-13 Common Stock 434000 434000 D Stock Option (right to buy) 2.85 2018-01-31 Common Stock 48448 48448 D Stock Options (right to buy) 2.94 2016-07-28 Common Stock 28929 28929 D Stock Options (right to buy) 2.05 2016-07-27 Common Stock 17730 17730 D Stock Options (right to buy) 3.4 2007-10-21 2016-10-21 Common Stock 5147 5147 D Stock Options (right to buy) 3.03 2015-12-01 Common Stock 49000 49000 D Stock Options (right to buy) 2.42 2017-01-26 Common Stock 45891 45891 D Stock Options (right to buy) 4.13 2007-07-25 2017-07-25 Common Stock 20000 20000 D None of these stock options have vested and vesting of such options is subject to the continued employment of the reporting person. None of these stock options have vested and vesting of such options is subject to the continued employment of the reporting person. 25,952 of these stock options have vested and are exercisable, whereas the remainder of such options has not yet vested, subject to the continued employment of the reporting person. 5,910 of these stock options have vested and are exercisable , whereas the remainder of such options has not yet vested, subject to the continued employment of the reporting person. 32,666 of these stock options have vested and are exercisable, whereas the remainder of such options has not yet vested, subject to the continued employment of the reporting person. 30,591 of these stock options have vested and are exercisable, whereas the remainder of such options has not yet vested, subject to the continued employment of the reporting person. /s/ Mark A. Sirgo 2008-03-13