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Notes Payable - Additional Information (Detail) - USD ($)
12 Months Ended
May 23, 2019
Dec. 31, 2020
Bio Pharma Credit Plc    
Debt Instrument [Line Items]    
Maximum borrowing capacity $ 60,000,000  
Additional facility that can be obtained 20,000,000  
Debt instrument, face amount 60,000,000  
Additional borrowing of face amount 1,800,000  
Loan agreement term   72 months
Loan agreement interest only term   36 months
Bio Pharma Credit Plc | LIBOR    
Debt Instrument [Line Items]    
Additional interest rate   7.50%
Bio Pharma Credit Plc | LIBOR | Minimum    
Debt Instrument [Line Items]    
Additional interest rate   2.00%
CRG    
Debt Instrument [Line Items]    
Back end facility fee $ 5,600,000  
CRG | Interest Expense    
Debt Instrument [Line Items]    
Debt issuance costs   $ 5,200,000
Amortization of discount   3,900,000
Loan preclosure fees   $ 2,800,000