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Income Taxes (Tables)
12 Months Ended
Dec. 31, 2019
Income Tax Disclosure [Abstract]  
Reconciliation of Federal Statutory Income Tax Rate
Reconciliation of the Federal statutory income tax rate of 21% to the effective rate is as follows:
201920182017
Federal statutory income (benefit) tax rate21.00 %21.00 %(34.00)%
2017 Tax Act, net deferred tax remeasurement—  —  (626.73) 
State taxes, net of federal benefit(0.18) (0.11) (2.01) 
Stock compensation(5.39) (4.74) (5.18) 
Permanent differences-other(7.67) (1.33) (13.39) 
North Carolina tax rate change—  —  (32.75) 
Research and development (“R&D”) credit—  —  5.54  
Valuation release for bargain purchase gain—  —  (302.23) 
Other1.71  (2.07) (1.36) 
Decrease (increase) in valuation allowance(9.44) (12.65) 709.88  
0.03 %0.10 %(302.23)%
Significant Components of Deferred Tax Assets and Liabilities
The tax effects of temporary differences and net operating losses that give rise to significant components of deferred tax assets and liabilities consist of the following:
December 31,
Deferred tax assets (liabilities)20192018
Basis difference in equipment$(438)$(459)
Basis difference in intangibles(5,356) (6,045) 
Accrued liabilities and other3,942  2,246  
R&D credit10,980  10,980  
Stock options4,416  4,360  
Net operating loss carry-forward62,535  64,376  
76,079  75,458  
Less: valuation allowance(76,079) (75,458) 
$—  $—