X0306 4 2018-03-07 0 0001103021 BIODELIVERY SCIENCES INTERNATIONAL INC BDSI 0001066040 ODONNELL FRANCIS E JR C/O BIODELIVERY SCIENCES INTL, INC., 4131 PARKLAKE AVENUE, SUITE 225 RALEIGH NC 27612 1 0 0 0 Common Stock 2018-03-07 4 M 0 48418 0.00 A 319717 D Common Stock 2018-03-07 4 M 0 46000 0.00 A 365717 D Common Stock 2018-03-07 4 S 0 47210 2.13 D 318507 D Common Stock 2018-03-08 4 M 0 133333 0.00 A 451840 D Common Stock 2018-03-08 4 S 0 66666 2.14 D 385174 D Restricted Stock Units 0.00 2018-03-07 4 M 0 48418 0.00 D 2018-03-07 2018-03-07 Common Stock 48418 0 D Restricted Stock Units 0.00 2018-03-07 4 M 0 46000 0.00 D 2018-03-07 2019-03-01 Common Stock 46000 92000 D Restricted Stock Units 0.00 2018-03-08 4 M 0 133333 0.00 D 2018-03-08 2018-09-12 Common Stock 133333 133333 D The shares of common stock were acquired by the Reporting Person as a result of the vesting of 48,418 of Restricted Stock Units ("RSUs") granted to the Reporting Person on February 22, 2014 under the Issuer's 2011 Equity Incentive Plan, as amended (the "Plan"). Pursuant to a deferral, these RSUs vested on March 7, 2018. The shares of common stock were acquired by the Reporting Person as a result of the vesting of one-third of the RSUs granted to the Reporting Person on February 29, 2016 under the Plan. Pursuant to a deferral, the remainder of the RSUs under this grant will vest in equal portions on each of (i) September 13, 2018 and (ii) March 1, 2019. The shares of common stock were sold under a pre-planned 10b5-1 trading plan and were sold to cover the Reporting Person's tax liability upon the vesting of RSUs. On March 7, 2018, the Reporting Person sold an aggregate of 47,210 shares of the Issuer's Common Stock at a weighted average price of $2.13 per share. The highest sale price for the Common Stock was $2.20 per share and the lowest sale price was $2.10 per share. The Reporting Person undertakes to provide the Company, any security holder of the Company or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. The shares of common stock were acquired by the Reporting Person as a result of the vesting of one-third of the RSUs granted to the Reporting Person on February 23, 2015 under the Plan. Pursuant to a deferral, these RSUs vested on March 8, 2018. Pursuant to a deferral, the remainder of the RSUs under this grant will vest in equal portions on September 12, 2018. On March 8, 2018, the Reporting Person sold an aggregate of 66,666 shares of the Issuer's Common Stock at a weighted average price of $2.14 per share. The highest sale price for the Common Stock was $2.18 per share and the lowest sale price was $2.10 per share. The Reporting Person undertakes to provide the Company, any security holder of the Company or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. /s/ Francis E. O'Donnell Jr. 2018-03-09