X0306 4 2016-03-17 0 0001103021 BIODELIVERY SCIENCES INTERNATIONAL INC BDSI 0001588538 De Paolantonio Ernest Robert C/O BIODELIVERY SCIENCES INTL, INC., 4131 PARKLAKE AVENUE, SUITE 225 RALEIGH NC 27612 0 1 0 0 CFO, Secretary and Treasurer Common Stock 2016-03-17 4 P 0 4000 2.60 A 13383 D /s/ Ernest R. De Paolantonio 2016-03-17