X0306 4 2023-02-16 0001101239 EQUINIX INC EQIX 0001219928 MORANDI BRANDI GALVIN C/O EQUINIX, INC. ONE LAGOON DRIVE REDWOOD CITY CA 94065 1 Chief Legal and HR Officer Common Stock 2023-02-16 4 S 0 100 684.41 D 22128 D Common Stock 2023-02-16 4 S 0 200 687.345 D 21928 D Common Stock 2023-02-16 4 S 0 100 705.02 D 21828 D Common Stock 2023-02-16 4 S 0 100 706.08 D 21728 D Common Stock 2023-02-16 4 S 0 300 712.1067 D 21428 D Common Stock 2023-02-16 4 S 0 400 714.22 D 21028 D Common Stock 2023-02-16 4 S 0 434 720.1906 D 20594 D Common Stock 2023-02-16 4 S 0 166 721.1969 D 20428 D Common Stock 2023-02-16 4 S 0 51 722.4057 D 20377 D Shares were sold pursuant to a 10b5-1 Trading Plan in order to raise funds to pay the required withholding tax pursuant to the vesting of RSUs. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $687.32 to $687.37, inclusive. The reporting person undertakes to provide to Equinix, Inc, any security holder of Equinix Inc, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes 3 through 7 to this Form 4. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $711.96 to $712.35 inclusive. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $713.74 to $714.67 inclusive. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $719.67 to $720.31 inclusive. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $720.76 to $721.4852 inclusive. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $722.38 to $722.5219 inclusive. /s/ Samantha Lagocki, POA 2023-02-17