X0306 4 2022-08-10 0001101239 EQUINIX INC EQIX 0001219928 MORANDI BRANDI GALVIN C/O EQUINIX, INC. ONE LAGOON DRIVE REDWOOD CITY CA 94065 1 Chief Legal and HR Officer Common Stock 2022-08-10 4 S 0 3356 710.1528 D 17284 D Shares sold pursuant to a 10b5-1 Trading Plan. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $710.00 to $711.00, inclusive. The reporting person undertakes to provide to Equinix, Inc, any security holder of Equinix Inc, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote to this Form 4. /s/ Samantha Lagocki, POA 2022-08-11