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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 COhDi2n9d4V0CHIDZ3WlOkgsfyDurCVt03Q7eE+LBIccWoN6IWe7r8zKWpSxtuUT
 geMQm/F9t7PuHEmjHvmkbg==

<SEC-DOCUMENT>0001209191-05-017907.txt : 20050329
<SEC-HEADER>0001209191-05-017907.hdr.sgml : 20050329
<ACCEPTANCE-DATETIME>20050329201712
ACCESSION NUMBER:		0001209191-05-017907
CONFORMED SUBMISSION TYPE:	4/A
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20050224
FILED AS OF DATE:		20050329
DATE AS OF CHANGE:		20050329

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			MYOGEN INC
		CENTRAL INDEX KEY:			0001101052
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				841348020
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		7575 WEST 103RD AVENUE STE 102
		CITY:			WESTMINSTER
		STATE:			CO
		ZIP:			80021
		BUSINESS PHONE:		3034106666

	MAIL ADDRESS:	
		STREET 1:		7575 WEST 103RD AVENUE STE 102
		CITY:			WESTMINSTER
		STATE:			CO
		ZIP:			80021

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			FREYTAG J WILLIAM
		CENTRAL INDEX KEY:			0001266124

	FILING VALUES:
		FORM TYPE:		4/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-50438
		FILM NUMBER:		05711153

	BUSINESS ADDRESS:	
		STREET 1:		7575 WEST 103RD AVENUE
		STREET 2:		SUITE 102
		CITY:			WESTMINSTER
		STATE:			CO
		ZIP:			80021
		BUSINESS PHONE:		3034106666
</SEC-HEADER>
<DOCUMENT>
<TYPE>4/A
<SEQUENCE>1
<FILENAME>bdn23257_bdn5bf.xml
<DESCRIPTION>MAIN DOCUMENT DESCRIPTION
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4/A</documentType>

    <periodOfReport>2005-02-24</periodOfReport>

    <dateOfOriginalSubmission>2005-02-28</dateOfOriginalSubmission>

    <issuer>
        <issuerCik>0001101052</issuerCik>
        <issuerName>MYOGEN INC</issuerName>
        <issuerTradingSymbol>MYOG</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001266124</rptOwnerCik>
            <rptOwnerName>FREYTAG J WILLIAM</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>MYOGEN, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>7575 WEST 103RD AVE, STE 102</rptOwnerStreet2>
            <rptOwnerCity>WESTMINSTER</rptOwnerCity>
            <rptOwnerState>CO</rptOwnerState>
            <rptOwnerZipCode>80021</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>Chairman, Pres &amp; CEO</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable></nonDerivativeTable>

    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>Stock Option (right to buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>8.48</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2005-02-24</value>
            </transactionDate>
            <deemedExecutionDate>
                <value>2005-02-24</value>
            </deemedExecutionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>44790</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <footnoteId id="F1"/>
            </exerciseDate>
            <expirationDate>
                <value>2010-02-23</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>44790</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>44790</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeTransaction>
        <derivativeTransaction>
            <securityTitle>
                <value>Stock Option (right to buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>8.48</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2005-02-24</value>
            </transactionDate>
            <deemedExecutionDate>
                <value>2005-02-24</value>
            </deemedExecutionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>67500</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <value>2006-02-24</value>
                <footnoteId id="F2"/>
            </exerciseDate>
            <expirationDate>
                <value>2015-02-23</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>67500</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>67500</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">The option fully vests upon the first to occur of (1) the average of Issuer's stock price for 5 consecutive trading days equals or exceeds a pre-determined level (&quot;Milestone Price&quot;), (2) Issuer's stock price equals or exceeds the Milestone Price on the final trading day before a change in control, (3) the total consideration payable to Issuer's stockholders in a change of control in exchange for 1 share of Issuer's Common Stock, calculated on the date of execution of a definitive agreement relating to the change in control equals or exceeds the Milestone Price, or (4) the total consideration actually received by Issuer's stockholders in a change in control for one share of Issuer's Common Stock, calculated as of the closing of the change in control, equals or exceeds the Milestone Price. The stock price shall be determined by the last reported sale price of Issuer's Common Stock on an exchange. The option terminates immediately prior to a change in control if the option ha
s not vested.</footnote>
        <footnote id="F2">25% of the options vest on the first anniversary of the date of grant.  The remaining 75% vest in 36 equal monthly installments thereafter.  The option expires ten years after the date of grant.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Brent D. Fassett, Attorney-in-Fact</signatureName>
        <signatureDate>2005-03-29</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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