X0303 4 2010-02-26 0 0001100962 ENDO PHARMACEUTICALS HOLDINGS INC ENDP 0001455549 Sweeney Edward J C/O ENDO PHARMACEUTICALS HOLDINGS INC. 100 ENDO BOULEVARD CHADDS FORD PA 19317 0 1 0 0 Principal Accounting Officer Common Stock, par value $.01 per share 2010-02-26 4 M 0 1110 0.00 A 1805 D Common Stock, par value $.01 per share 2010-03-01 4 S 0 695 21.69 D 1110 D Common Stock, par value $.01 per share 2010-03-01 4 S 0 1110 22.34 D 0 D 2007 Stock Incentive Plan Restricted Stock Units(RSUs) 2010-02-26 4 M 0 1110 0.00 D 2010-02-26 2010-02-26 Common Stock 1110 3329 D This represents the vesting of restricted stock units granted to Mr. Sweeney on February 26, 2009. Upon each vesting date, each vested restricted stock unit automatically converts into one (1) share of common stock of Endo Pharmaceuticals Holdings Inc. These shares represent common stock received by Mr. Sweeney on February 22, 2010 upon the vesting of RSUs, as reported on Form 4 on February 23, 2010. Upon each vesting date, each vested restricted stock unit automatically converts into one (1) share of common stock of Endo Pharmaceuticals Holdings Inc. Twenty-five percent (25%) of Mr. Sweeney's February 26, 2009 grant of restricted stock units (RSUs) generally vest 25% on each of February 26, 2010, February 26, 2011, February 26, 2012 and February 26, 2013. The 1,110 shown here is the amount that vested on February 26, 2010. Upon vesting, we consider the underlying RSUs to be expired. /s/ Caroline B. Manogue, by Power of Attorney 2010-03-02