10-Q

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

____________________________________________

FORM 10-Q

(Mark One)
ý	QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934
FOR THE QUARTERLY PERIOD ENDED MARCH 31, 2012
OR
o	TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934
FOR THE TRANSITION PERIOD FROM                                    TO

Commission File No. 001-15943

CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

(Exact Name of Registrant as Specified in Its Charter)

Delaware	06-1397316
(State or Other Jurisdiction of Incorporation or Organization)	(I.R.S. Employer Identification No.)
251 Ballardvale Street Wilmington, Massachusetts (Address of Principal Executive Offices)	01887 (Zip Code)

____________________________________________________________________________

(Registrant's telephone number, including area code): (781) 222-6000

_________________________________________________________

Indicate by check mark whether the Registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the Registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days. Yes ý No o

Indicate by check mark whether the registrant has submitted electronically and posted on its corporate Website, if any, every Interactive Data File required to be submitted and posted pursuant to Rule 405 of Regulation S-T (§ 232.405 of this chapter) during the preceding 12 months (or for such shorter period that the registrant was required to submit and post such files. Yes ý No o

Indicate by check mark whether the Registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, or a smaller reporting company. See the definitions of "large accelerated filer," "accelerated filer" and "smaller reporting company" in Rule 12b-2 of the Exchange Act.

Large accelerated filer ý Accelerated filer o Non-accelerated filer o (Do not check if smaller reporting company) Smaller reporting company o

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act). Yes o    No ý

As of April 20, 2012, there were 48,995,692 shares of the Registrant's common stock outstanding.

CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

FORM 10-Q

For the Quarterly Period Ended March 31, 2012

TABLE OF CONTENTS

			Page
Part I.	Financial Information
	Item 1.	Financial Statements
		Condensed Consolidated Statements of Income (Unaudited) for the three months ended March 31, 2012 and March 26, 2011	3
		Condensed Consolidated Statements of Comprehensive Income (Unaudited) for the three months ended March 31, 2012 and March 26, 2011	4
		Condensed Consolidated Balance Sheets (Unaudited) as of March 31, 2012 and December 31, 2011	5
		Condensed Consolidated Statements of Cash Flows (Unaudited) for the three months ended March 31, 2012 and March 26, 2011	6
		Condensed Consolidated Statement of Changes in Equity (Unaudited) for the three months ended March 31, 2012	7
		Notes to Condensed Consolidated Interim Financial Statements	8
	Item 2.	Management's Discussion and Analysis of Financial Condition and Results of Operations	23
	Item 3.	Quantitative and Qualitative Disclosure About Market Risk	28
	Item 4.	Controls and Procedures	28
Part II.	Other Information
	Item 1A.	Risk Factors	29
	Item 2.	Unregistered Sales of Equity Securities and Use of Proceeds	29
	Item 6.	Exhibits	30

1

Special Note on Factors Affecting Future Results

This Quarterly Report on Form 10-Q contains forward‑looking statements regarding future events and the future results of Charles River Laboratories International, Inc. (Charles River or We) that are based on current expectations, estimates, forecasts, and projections about the industries in which Charles River operates and the beliefs and assumptions of our management. Words such as “expect,” “anticipate,” “target,” “goal,” “project,” “intend,” “plan,” “believe,” “seek,” “estimate,” “will,” “likely,” “may,” “designed,” “would,” “future,” “can,” “could” and other similar expressions that are predictions of or indicate future events and trends or which do not relate to historical matters are intended to identify such forward‑looking statements. These statements are based on our current expectations and beliefs and involve a number of risks, uncertainties, and assumptions that are difficult to predict. For example, we may use forward‑looking statements when addressing topics such as: the pursuit of our initiatives to optimize returns for stockholders, including efforts to improve our operating margins, improve free cash flow, invest in growth businesses and return value to shareholders; future demand for drug discovery and development products and services, including the outsourcing of these services and spending trends by our customers; our expectations regarding stock repurchases; present spending trends and other cost reduction activities by our customers; future actions by our management; the outcome of contingencies; changes in our business strategy; changes in our business practices and methods of generating revenue; the development and performance of our services and products; market and industry conditions, including competitive and pricing trends; changes in the composition or level of our revenues; our cost structure; the impact of acquisitions and dispositions; our expectations with respect to sales growth and operating synergies (including the impact of specific actions intended to cause related improvements); the impact of specific actions intended to improve overall operating efficiencies and profitability (and our ability to accommodate future demand with our infrastructure); changes in our expectations regarding future stock option, restricted stock, and other equity grants to employees and directors; expectations with respect to foreign currency exchange; assessing (or changing our assessment of) our tax positions for financial statement purposes; and our cash flow and liquidity. In addition, these statements include the impact of economic and market conditions on our customers; the effects of our cost-saving actions and the steps to optimize returns to shareholders on an effective and timely basis and the ability of Charles River to withstand the current market conditions. You should not rely on forward‑looking statements because they are predictions and are subject to risks, uncertainties and assumptions that are difficult to predict. Therefore, actual results may differ materially and adversely from those expressed in any forward‑looking statements. You are cautioned not to place undue reliance on these forward‑looking statements, which speak only as of the date of this document or in the case of statements incorporated by reference, on the date of the document incorporated by reference. Factors that might cause or contribute to such differences include, but are not limited to, those discussed in our Annual Report on Form 10-K for the year ended December 31, 2011 under the section entitled “Our Strategy,” the section entitled “Risks Related to Our Business and Industry,” the section entitled “Management's Discussion and Analysis of Financial Condition and Results of Operations” and in our press releases and other financial filings with the Securities and Exchange Commission. We have no obligation to publicly update or revise any forward‑looking statements, whether as a result of new information, future events or risks. New information, future events or risks may cause the forward‑looking events we discuss in this report not to occur.

2

Part I. Financial Information

Item 1. Financial Statements

CHARLES RIVER LABORATORIES INTERNATIONAL, INC.
CONDENSED CONSOLIDATED STATEMENTS OF INCOME (UNAUDITED)

(dollars in thousands, except per share amounts)

	Three Months Ended
	March 31, 2012			March 26, 2011
Net sales related to products	$	126,214		$	121,396
Net sales related to services	159,767			164,447
Net sales	285,981			285,843
Costs and expenses
Cost of products sold	64,945			65,766
Cost of services provided	116,824			117,439
Selling, general and administrative	55,977			55,007
Amortization of other intangibles	4,495			5,380
Operating income	43,740			42,251
Other income (expense)
Interest income	185			364
Interest expense	(8,435		)	(10,016		)
Other, net	(344		)	63
Income from continuing operations, before income taxes	35,146			32,662
Provision (benefit) for income taxes	8,676			(2,715		)
Income from continuing operations, net of income taxes	26,470			35,377
Income (loss) from discontinued operations, net of taxes	77			(3,945		)
Net income	26,547			31,432
Less: Net income attributable to noncontrolling interests	(108		)	(97		)
Net income attributable to common shareowners	$	26,439		$	31,335
Earnings (loss) per common share
Basic:
Continuing operations attributable to common shareowners	$	0.55		$	0.65
Discontinued operations	$	—		$	(0.07	)
Net income attributable to common shareowners	$	0.55		$	0.58
Diluted:
Continuing operations attributable to common shareowners	$	0.54		$	0.65
Discontinued operations	$	—		$	(0.07	)
Net income attributable to common shareowners	$	0.54		$	0.57

See Notes to Condensed Consolidated Interim Financial Statements.

3

CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE INCOME (UNAUDITED)

(dollars in thousands, except per share amounts)

	March 31, 2012			March 26, 2011
Net income	$	26,547		$	31,432
Foreign currency translation adjustment	6,780			8,258
Unrealized gains (losses) on marketable securities:
Unrealized gains (losses) for the period	209			(85		)
Add: reclassification adjustment for losses included in net income	712			—
Defined benefit plan gains (losses) and prior service costs not yet recognized as components of net periodic pension cost:
Prior service cost and gains (losses) for the period	—			—
Amortization of prior service costs and net gains and losses	661			263
Comprehensive income, before tax	34,909			39,868
Income tax expense related to items of other comprehensive income	261			204
Comprehensive income, net of tax	34,648			39,664
Less: comprehensive income related to noncontrolling interests	(126		)	(109		)
Comprehensive income attributable to common shareholders	$	34,522		$	39,555

See Notes to Condensed Consolidated Interim Financial Statements.

4

CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

CONDENSED CONSOLIDATED BALANCE SHEETS (UNAUDITED)

(dollars in thousands, except per share amounts)

	March 31, 2012			December 31, 2011
Assets
Current assets
Cash and cash equivalents	$	61,031		$	68,905
Trade receivables, net	205,893			184,810
Inventories	89,347			92,969
Other current assets	80,892			79,052
Current assets of discontinued businesses	107			107
Total current assets	437,270			425,843
Property, plant and equipment, net	740,225			738,030
Goodwill, net	198,882			197,561
Other intangibles, net	90,454			93,437
Deferred tax asset	40,523			44,804
Other assets	47,045			57,659
Long-term assets of discontinued businesses	959			986
Total assets	$	1,555,358		$	1,558,320
Liabilities and Equity
Current liabilities
Current portion of long-term debt and capital leases	$	29,574		$	14,758
Accounts payable	32,353			34,332
Accrued compensation	40,199			41,602
Deferred revenue	58,195			56,530
Accrued liabilities	47,889			54,377
Other current liabilities	14,461			14,033
Current liabilities of discontinued businesses	1,164			1,165
Total current liabilities	223,835			216,797
Long-term debt and capital leases	674,743			703,187
Other long-term liabilities	99,823			108,451
Long-term liabilities of discontinued businesses	2,452			2,522
Total liabilities	1,000,853			1,030,957
Commitments and contingencies
Shareowners' equity
Preferred stock, $0.01 par value; 20,000,000 shares authorized; no shares issued and outstanding	—			—
Common stock, $0.01 par value; 120,000,000 shares authorized; 79,031,347 issued and 49,002,831 shares outstanding at March 31, 2012 and 78,473,888 issued and 48,875,715 shares outstanding at December 31, 2011	790			785
Capital in excess of par value	2,064,890			2,056,921
Accumulated deficit	(439,157		)	(465,596		)
Treasury stock, at cost, 30,028,516 shares and 29,598,173 shares at March 31, 2012 and December 31, 2011, respectively	(1,086,600		)	(1,071,120		)
Accumulated other comprehensive income	12,676			4,593
Total shareowners' equity	552,599			525,583
Noncontrolling interests	1,906			1,780
Total equity	554,505			527,363
Total liabilities and equity	$	1,555,358		$	1,558,320

See Notes to Condensed Consolidated Interim Financial Statements.

5

CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (UNAUDITED)

(dollars in thousands)

	Three Months Ended
	March 31, 2012			March 26, 2011
Cash flows relating to operating activities
Net income	$	26,547		$	31,432
Less: Income (loss) from discontinued operations	77			(3,945		)
Income from continuing operations	26,470			35,377
Adjustments to reconcile net income from continuing operations to net cash provided by operating activities:
Depreciation and amortization	20,002			21,265
Amortization of debt issuance costs and discounts	4,345			4,330
Non-cash compensation	5,266			5,919
Deferred income taxes	5,740			3,422
Other, net	1,535			518
Changes in assets and liabilities:
Trade receivables	(19,881		)	(17,166		)
Inventories	3,312			4,336
Other assets	(462		)	(406		)
Accounts payable	(2,187		)	2,170
Accrued compensation	(1,659		)	(4,188		)
Deferred revenue	963			(8,073		)
Accrued liabilities	(5,114		)	187
Taxes payable and prepaid taxes	(7,320		)	(23,365		)
Other liabilities	(5,733		)	(2,933		)
Net cash provided by operating activities	25,277			21,393
Cash flows relating to investing activities
Capital expenditures	(14,112		)	(6,789		)
Purchases of investments	(4,694		)	(9,548		)
Proceeds from sale of investments	14,555			3,655
Other, net	973			146
Net cash used in investing activities	(3,278		)	(12,536		)
Cash flows relating to financing activities
Proceeds from long-term debt and revolving credit agreement	28,000			150,607
Proceeds from exercises of stock options and warrants	2,715			5,239
Payments on long-term debt, capital lease obligation and revolving credit agreement	(46,566		)	(9,766		)
Purchase of treasury stock and Accelerated Stock Repurchase Program	(15,246		)	(174,465		)
Other, net	462			(876		)
Net cash used in financing activities	(30,635		)	(29,261		)
Discontinued operations
Net cash used in operating activities	—			(38		)
Net cash provided by financing activities	—			213
Net cash provided by discontinued operations	—			175
Effect of exchange rate changes on cash and cash equivalents	762			(186		)
Net change in cash and cash equivalents	(7,874		)	(20,415		)
Cash and cash equivalents, beginning of period	68,905			179,160
Cash and cash equivalents, end of period	$	61,031		$	158,745
Supplemental cash flow information
Capitalized interest	$	191		$	92

See Notes to Condensed Consolidated Interim Financial Statements.

6

CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

CONDENSED CONSOLIDATED STATEMENTS OF CHANGES IN EQUITY (UNAUDITED)

(dollars in thousands)

	Total			Accumulated (Deficit) Earnings			Accumulated Other Comprehensive Income		Common Stock		Capital in Excess of Par			Treasury Stock			Non-controlling Interest
December 31, 2011	$	527,363		$	(465,596	)	$	4,593	$	785	$	2,056,921		$	(1,071,120	)	$	1,780
Components of comprehensive income, net of tax:
Net income	26,547			26,439													108
Other comprehensive income	8,101						8,083										18
Total comprehensive income	34,648																126
Tax detriment associated with stock issued under employee compensation plans	(5		)								(5		)
Issuance of stock under employee compensation plans	2,713								5		2,708
Acquisition of treasury shares	(15,480		)								—			(15,480		)
Stock-based compensation	5,266										5,266
March 31, 2012	$	554,505		$	(439,157	)	$	12,676	$	790	$	2,064,890		$	(1,086,600	)	$	1,906

See Notes to Condensed Consolidated Interim Financial Statements.

7

CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

NOTES TO UNAUDITED CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS

(dollars in thousands, except per share amounts)

1. Basis of Presentation

The condensed consolidated interim financial statements are unaudited, and certain information and footnote disclosures related thereto normally included in financial statements prepared in accordance with generally accepted accounting principles in the United States of America have been omitted in accordance with Rule 10-01 of Regulation S-X. In the opinion of management, the accompanying unaudited condensed consolidated financial statements were prepared following the same policies and procedures used in the preparation of the audited financial statements and reflect all adjustments (consisting of normal recurring adjustments) considered necessary to state fairly the financial position and results of operations of Charles River Laboratories International, Inc. The results of operations for the interim periods are not necessarily indicative of the results for the entire fiscal year. These condensed consolidated financial statements should be read in conjunction with our Annual Report on Form 10-K for the year ended December 31, 2011.

Certain amounts in prior-year financial statements and related notes have been reclassified to conform with the current year presentation.

2. Restructuring and Contract Termination Costs

We have implemented staffing reductions over the past few years to improve operating efficiency and profitability at various sites. As a result of these actions, for the three months ended March 31, 2012 and March 26, 2011, we recorded severance and retention charges as shown below. As of March 31, 2012, $1,892 was included in accrued compensation and $1,785 in other long-term liabilities on our consolidated balance sheet.

The following table rolls forward our severance and retention cost liability:

	Three Months Ended
	March 31, 2012			March 26, 2011
Balance, beginning of period	$	3,374		$	10,658
Expense	911			494
Payments/utilization	(608		)	(4,052		)
Balance, end of period	$	3,677		$	7,100

The following table presents severance and retention costs by classification on the income statement:

	Three Months Ended
	March 31, 2012		March 26, 2011
Severance charges included in cost of sales	$	—	$	241
Severance charges included in selling, general and administrative expense	911		253
Total expense	$	911	$	494

The following table presents severance and retention cost by segment:

	Three Months Ended
	March 31, 2012		March 26, 2011
Research models and services	$	—	$	229
Preclinical services	911		257
Corporate	—		8
Total expense	$	911	$	494

8

CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

NOTES TO UNAUDITED CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS (Continued)

(dollars in thousands, except per share amounts)

3. Supplemental Balance Sheet Information

The composition of net trade receivables is as follows:

	March 31, 2012			December 31, 2011
Client receivables	$	178,547		$	159,381
Unbilled revenue	31,816			29,446
Total	210,363			188,827
Less allowance for doubtful accounts	(4,470		)	(4,017		)
Net trade receivables	$	205,893		$	184,810

The composition of inventories is as follows:

	March 31, 2012		December 31, 2011
Raw materials and supplies	$	13,808	$	13,987
Work in process	13,372		13,533
Finished products	62,167		65,449
Inventories	$	89,347	$	92,969

The composition of other current assets is as follows:

	March 31, 2012		December 31, 2011
Prepaid assets	$	22,269	$	22,828
Deferred tax asset	26,608		30,894
Marketable securities	6,136		5,359
Prepaid income tax	25,650		19,742
Restricted cash	229		229
Other current assets	$	80,892	$	79,052

The composition of net property, plant and equipment is as follows:

	March 31, 2012			December 31, 2011
Land	$	40,435		$	40,517
Buildings	696,193			696,275
Machinery and equipment	351,761			348,795
Leasehold improvements	27,987			29,975
Furniture and fixtures	12,214			10,663
Vehicles	5,252			5,226
Computer hardware and software	105,243			105,563
Construction in progress	60,735			57,661
Total	1,299,820			1,294,675
Less accumulated depreciation	(559,595		)	(556,645		)
Net property, plant and equipment	$	740,225		$	738,030

9

CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

NOTES TO UNAUDITED CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS (Continued)

(dollars in thousands, except per share amounts)

Depreciation is calculated for financial reporting purposes using the straight-line method based on the estimated useful lives of the assets. Depreciation expense for the quarter ended March 31, 2012 and March 26, 2011 was $15,507 and $15,885, respectively.

The composition of other assets is as follows:

	March 31, 2012		December 31, 2011
Deferred financing costs	$	8,408	$	9,239
Cash surrender value of life insurance policies	25,706		25,057
Long term marketable securities	—		11,051
Other assets	12,931		12,312
Other assets	$	47,045	$	57,659

The composition of other current liabilities is as follows:

	March 31, 2012		December 31, 2011
Accrued income taxes	$	8,983	$	10,552
Current deferred tax liability	1,415		1,379
Accrued interest and other	4,063		2,102
Other current liabilities	$	14,461	$	14,033

The composition of other long-term liabilities is as follows:

	March 31, 2012		December 31, 2011
Deferred tax liability	$	13,602	$	16,074
Long-term pension liability	43,347		49,223
Accrued Executive Supplemental Life Insurance Retirement Plan and Deferred Compensation Plan	25,914		25,739
Other long-term liabilities	16,960		17,415
Other long-term liabilities	$	99,823	$	108,451

4. Marketable Securities and Equity-Method Affiliates

Investments in marketable securities are reported at fair value and consist of time deposits and auction rate securities. During the period ended March 31, 2012, we sold our auction rate securities for $11,260 in cash and recorded a realized loss of $712, which is included in other income (expense).

The amortized cost, gross unrealized gains, gross unrealized losses and fair value for marketable securities by major security type were as follows:

	March 31, 2012
	Amortized Cost		Gross Unrealized Gains		Gross Unrealized Losses		Fair Value
Time deposits	$	6,136	$	—	$	—	$	6,136
Auction rate securities	—		—		—		—
	$	6,136	$	—	$	—	$	6,136

10

CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

NOTES TO UNAUDITED CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS (Continued)

(dollars in thousands, except per share amounts)

	December 31, 2011
	Amortized Cost		Gross Unrealized Gains		Gross Unrealized Losses			Fair Value
Time deposits	$	5,359	$	—	$	—		$	5,359
Auction rate securities	11,972		—		(921		)	11,051
	$	17,331	$	—	$	(921	)	$	16,410

Maturities of debt securities were as follows:

	March 31, 2012				December 31, 2011
	Amortized Cost		Fair Value		Amortized Cost		Fair Value
Due less than one year	$	6,136	$	6,136	$	5,359	$	5,359
Due after one year through five years	—		—		—		—
Due after ten years	—		—		11,972		11,051
	$	6,136	$	6,136	$	17,331	$	16,410

Equity-Method Affiliates

In 2009, we entered into a limited partnership, which invests in biotechnology and medical device companies. We committed $20,000, or approximately 12%, of the limited partnership's total committed capital. As of March 31, 2012, we have contributed $6,147 of our total committed capital of $20,000. We recognized equity income of $397 for the three months ended March 31, 2012. This income is reported as other income (expense). As of March 31, 2012, Equity Method Affiliates had a carrying value of $6,834, which is reported in other assets on the consolidated balance sheets.

5. Fair Value

Valuation methodologies used for assets and liabilities measured or disclosed at fair value are as follows:

• Time deposits—Valued at their ending balances as reported by the financial institutions that hold our securities, which approximates fair value.

• Life policies—Valued at cash surrender value.

• Contingent consideration—Consists of future acquisition-related payments based on certain agreed upon revenue and technical milestones valued using the income approach.

• Hedge contract—Valued at fair value by management based on our foreign exchange rates and forward points provided by banks.

• Long-term debt—Valued based on current market pricing for similar debt.

Assets and liabilities measured at fair value on a recurring basis are summarized below:

11

CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

NOTES TO UNAUDITED CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS (Continued)

(dollars in thousands, except per share amounts)

	Fair Value Measurements at March 31, 2012 using
	Quoted Prices in Active Markets for Identical Assets Level 1		Significant Other Observable Inputs Level 2		Significant Unobservable Inputs Level 3		Assets and Liabilities at Fair Value
Time deposits	$	—	$	6,136	$	—	$	6,136
Auction rate securities	—		—		—		—
Fair value of life policies	—		20,116		—		20,116
Hedge contract	—		96		—		96
Total assets measured at fair value	$	—	$	26,348	$	—	$	26,348
Contingent consideration	—		—		—		—
Total liabilities measured at fair value	$	—	$	—	$	—	$	—

	Fair Value Measurements at December 31, 2011 using
	Quoted Prices in Active Markets for Identical Assets Level 1		Significant Other Observable Inputs Level 2		Significant Unobservable Inputs Level 3		Assets and Liabilities at Fair Value
Time deposits	$	—	$	5,359	$	—	$	5,359
Auction rate securities	—		—		11,051		11,051
Fair value of life policies	—		19,520		—		19,520
Hedge contract	—		5		—		5
Total assets measured at fair value	$	—	$	24,884	$	11,051	$	35,935
Contingent consideration	—		—		—		—
Total liabilities measured at fair value	$	—	$	—	$	—	$	—

The book value of our term and revolving loans, which are variable rate loans carried at amortized cost, approximates fair value based current market pricing of similar debt. The fair value of our 2.25% Senior Convertible Debentures (2013 Notes), which are carried at cost less unamortized discount on our consolidated balance sheets, was $354,195 as of March 31, 2012. We determine the fair value of these 2013 Notes based on their most recent quoted market price and by reference to the market value of similar debt instruments. We classify the fair value of our debt as Level 2 (significant other observable inputs) on the valuation hierarchy, where Level 2 inputs include quoted prices for similar assets and liabilities in active markets and/or quoted prices for identical or similar assets and liabilities in markets that are not active.

The following table presents a reconciliation for all assets measured at fair value on a recurring basis using significant unobservable inputs (Level 3) during the years ended March 31, 2012 and December 31, 2011. As of December 31, 2011, our auction rate securities were valued at fair value by management in part utilizing an independent valuation, which used pricing models and discounted cash flow methodologies incorporating assumptions that reflect the assumptions a marketplace participant would use.

12

CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

NOTES TO UNAUDITED CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS (Continued)

(dollars in thousands, except per share amounts)

	Fair Value Measurements Using Significant Unobservable Inputs (Level 3)
	Three Months Ended
Auction rate securities	March 31, 2012			March 26, 2011
Beginning balance	$	11,051		$	11,377
Transfers in and/or out of Level 3	—			—
Total gains or losses (realized/unrealized):
Included in other income (expense)	(712		)	(1		)
Included in other comprehensive income	921			(85		)
Purchases, issuances and settlements	(11,260		)	—
Ending balance	$	—		$	11,291

We enter into derivative instruments to hedge foreign currency exchange risk to reduce the impact of changes to foreign currency rates on our financial statements. During the quarter ended March 31, 2012, we recognized $123 of hedge gains associated with forward currency contracts open during the quarter. As of March 31, 2012, outstanding forward currency contracts had a fair value of $96.

6. Goodwill and Other Intangible Assets

The following table displays goodwill and other intangible assets not subject to amortization and other intangible assets that continue to be subject to amortization:

	March 31, 2012					December 31, 2011
	Gross Carrying Amount		Accumulated Amortization & Impairment Loss			Gross Carrying Amount		Accumulated Amortization & Impairment Loss
Goodwill	$	1,215,639	$	(1,016,757	)	$	1,214,285	$	(1,016,724	)
Other intangible assets not subject to amortization:
Research models	$	3,438	$	—		$	3,438	$	—
Other intangible assets subject to amortization:
Backlog	2,885		(2,293		)	2,856		(2,253		)
Client relationships	304,125		(219,045		)	298,813		(210,816		)
Client contracts	15,232		(15,232		)	14,818		(14,818		)
Trademarks and trade names	5,028		(4,738		)	5,022		(4,706		)
Standard operating procedures	652		(652		)	650		(650		)
Other identifiable intangible assets	5,464		(4,410		)	5,415		(4,332		)
Total other intangible assets	$	336,824	$	(246,370	)	$	331,012	$	(237,575	)

13

CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

NOTES TO UNAUDITED CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS (Continued)

(dollars in thousands, except per share amounts)

The changes in the gross carrying amount and accumulated amortization of goodwill are as follows:

				Adjustments to Goodwill
	December 31, 2011			Acquisitions		Foreign Exchange/ Impairment			March 31, 2012
Research Models and Services
Gross carrying amount	$	56,402		$	—	$	309		$	56,711
Accumulated amortization	(3,721		)	—		(33		)	(3,754		)
Preclinical Services
Gross carrying amount	1,157,883			—		1,045			1,158,928
Accumulated impairment loss	(1,005,000		)	—		—			(1,005,000		)
Accumulated amortization	(8,003		)	—		—			(8,003		)
Total
Gross carrying amount	$	1,214,285		$	—	$	1,354		$	1,215,639
Accumulated impairment loss	(1,005,000		)	—		—			(1,005,000		)
Accumulated amortization	(11,724		)	—		(33		)	(11,757		)

7. Long-Term Debt and Capital Lease Obligations

Long-Term Debt

Long-term debt consists of the following:

	March 31, 2012			December 31, 2011
2.25% Senior convertible debentures:
Principal	$	349,995		$	349,995
Unamortized debt discount	(18,019		)	(21,533		)
Net carrying amount of senior convertible debentures	331,976			328,462
Term loan facilities	333,187			356,322
Revolving credit facility	39,000			33,000
Other long-term debt represents secured and unsecured promissory notes, interest rates ranging from 0% to 0.5% at both March 31, 2012 and December 31, 2011, maturing between 2012 and 2013	122			118
Total debt	704,285			717,902
Less: current portion of long-term debt	(29,549		)	(14,732		)
Long-term debt	$	674,736		$	703,170

Our credit agreement dated September 23, 2011 provides for a $299,750 term loan, a €69,414 Euro term loan and a $350,000 revolving credit facility. The term loan facility matures in 20 quarterly installments with the last installment due September 23, 2016. The $350,000 revolving facility also matures on September 23, 2016 and requires no scheduled payment before that date. The book value of our term and revolving loans approximates fair value.

The credit agreement includes certain customary representations and warranties, events of default, notices of material adverse changes to our business and negative and affirmative covenants. As of March 31, 2012, we were compliant with all financial covenants specified in the credit agreement. We had $4,325 outstanding under letters of credit as of March 31, 2012.

14

CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

NOTES TO UNAUDITED CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS (Continued)

(dollars in thousands, except per share amounts)

As of March 31, 2012, our debt included $349,995 of 2.25% Senior Convertible Debentures (2013 Notes) due June 2013. At March 31, 2012, the fair value of these outstanding 2013 Notes was approximately $354,195 based on their quoted market value and no conversion triggers were met.

As of March 31, 2012, $18,019 of debt discount related to the 2013 Notes remained and will be amortized over 5 quarters. Interest expense related to our convertible debt of $3,514 and $3,349 for quarters ending March 31, 2012 and March 26, 2011 respectively, yielded an effective interest rate of 6.93% on the liability component. In addition, $1,969 and $1,969 of contractual interest expense was recognized on our convertible debt during the years ended March 31, 2012 and March 26, 2011, respectively.

Principal maturities of existing debt, which excludes unamortized discount, for the periods set forth in the table below are as follows:

Twelve Months Ending
March 2013	$	29,549
March 2014	384,327
March 2015	63,759
March 2016	70,782
March 2017	173,887
Total	$	722,304

We have capital leases for equipment. These leases are capitalized using interest rates considered appropriate at the inception of the lease. Capital lease obligations amounted to $32 and $43 at March 31, 2012 and December 31, 2011, respectively.

8. Equity

Earnings Per Share

Basic earnings per share for the three months ended March 31, 2012 and March 26, 2011 was computed by dividing earnings available to common shareowners for these periods by the weighted average number of common shares outstanding in the respective periods adjusted for contingently issuable shares. The weighted average number of common shares outstanding for the three months ended March 31, 2012 and March 26, 2011 has been adjusted to include common stock equivalents for the purpose of calculating diluted earnings per share for these periods.

Options to purchase 4,395,903 shares and 4,490,167 shares were outstanding at March 31, 2012 and March 26, 2011, respectively, but were not included in computing diluted earnings per share because their inclusion would have been anti-dilutive. Basic weighted average shares outstanding for March 31, 2012 and March 26, 2011 excluded the weighted average impact of 930,193 and 761,173 shares, respectively, of non-vested fixed restricted stock awards.

The following table illustrates the reconciliation of the numerator and denominator in the computations of the basic and diluted earnings per share:

15

CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

NOTES TO UNAUDITED CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS (Continued)

(dollars in thousands, except per share amounts)

	Three Months Ended
	March 31, 2012		March 26, 2011
Numerator:
Income from continuing operations for purposes of calculating earnings per share	$	26,362	$	35,280
Income (loss) from discontinued businesses	77		$	(3,945	)
Denominator:
Weighted-average shares outstanding—Basic	48,254,950		53,937,948
Effect of dilutive securities:
2.25% senior convertible debentures	—		—
Stock options and contingently issued restricted stock	516,793		659,792
Weighted-average shares outstanding—Diluted	48,771,743		54,597,740
Basic earnings per share from continuing operations attributable to common shareowners	$	0.55	$	0.65
Basic earnings (loss) per share from discontinued operations attributable to common shareowners	$	—	$	(0.07	)
Diluted earnings per share from continuing operations attributable to common shareowners	$	0.54	$	0.65
Diluted earnings (loss) per share from discontinued operations attributable to common shareowners	$	—	$	(0.07	)

Treasury Shares

For the three months ended March 31, 2012 and March 26, 2011, we repurchased 347,968 shares of common stock for $12,500 and 579,200 shares of common stock for $21,607, respectively, through open market purchases made in reliance on Rule 10b5-1. Additionally, our 2000 Incentive Plan permits the netting of common stock upon vesting of restricted stock awards in order to satisfy individual tax withholding requirements. During the three months ended March 31, 2012 and March 26, 2011, we acquired 82,375 shares for $2,980 and 77,446 shares for $2,848, respectively, as a result of such withholdings. Additionally, the three months ended March 26, 2011 includes the acquisition of 4,631,227 shares under accelerated stock repurchase programs (ASR).

Share repurchases for the three months ended March 31, 2012 and March 26, 2011 were as follows:

	Three Months Ended
	March 31, 2012		March 26, 2011
Number of shares of common stock repurchased	430,343		5,287,873
Total cost of repurchase	$	15,480	$	192,834

9. Income Taxes

The following table provides a reconciliation of the provision for income taxes on the condensed consolidated statements of income:

	Three Months Ended
	March 31, 2012		March 26, 2011
Income from continuing operations before income taxes	35,146		32,662
Effective tax rate	24.7	%	(8.3	)%
Provision (benefit) for income taxes	8,676		(2,715	)

16

CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

NOTES TO UNAUDITED CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS (Continued)

(dollars in thousands, except per share amounts)

Our overall effective tax rate was 24.7% in the first quarter of 2012 and (8.3)% in the first quarter of 2011. The change was primarily attributable to an $11,111 tax benefit recorded in the first quarter of 2011 associated with a tax loss incurred with the disposition of our Phase I clinical business. Additionally, there was an increase in tax rate in the first quarter of 2012 compared to the first quarter of 2011 primarily due to an unbenefitted capital loss on the sale of auction rate securities incurred during the first quarter of 2012 and lower research and development tax benefits. These increases were partially offset by reductions in the tax rate in the first quarter of 2012 compared to the first quarter of 2011 due to increased benefits from the domestic production deduction and a reduction in unbenefitted losses primarily driven by the disposition of our preclinical services operations in Shanghai.

In accordance with Canadian Federal tax law, we claim scientific research and experimental development (SR&ED) credits on qualified research and development costs incurred by our preclinical services facility in Canada in the performance of projects for non-Canadian clients. Additionally, in accordance with the tax law of the United Kingdom, we claim enhanced deductions related to qualified research and development costs incurred by our preclinical services facility in Edinburgh, Scotland, in the performance of certain client contracts.

During the fourth quarter of 2010, we took actions to divest of our Phase 1 clinical business. We recorded in discontinued operations a deferred tax asset associated with the excess of the tax outside basis over the basis for financial reporting purposes of the Phase 1 clinical business. As of the fourth quarter of 2010, we determined that we did not meet the more-likely-than-not realization threshold for this deferred tax asset and we recorded a valuation allowance against it as part of discontinued operations. During the first quarter of 2011, we determined that the tax loss would more-likely-than-not be benefitted as a worthless stock deduction. As such, we released the valuation allowance recorded against the tax loss on the Phase 1 clinical business and recognized the benefit in continuing operations.

During the first quarter of 2012, our unrecognized tax benefits recorded increased by $744 to $28,720 primarily due to ongoing evaluation of uncertain tax positions in the current period and foreign exchange movement offset by the settlement of a U.S. state audit. The amount of unrecognized income tax benefits that would impact the effective tax rate favorably increased by $459 to $22,936, and the amount of accrued interest on unrecognized tax benefits decreased by $16 to $1,499 in the first quarter of 2012.

We conduct business in a number of tax jurisdictions. As a result, we are subject to tax audits in jurisdictions including, but not limited to, the United States, the United Kingdom, Japan, France, Germany and Canada. With few exceptions, we are no longer subject to U.S. and international income tax examinations for years before 2005.

We and certain of our subsidiaries are currently under audit by the Canadian Revenue Authority (CRA), the Minister of Revenue Quebec provincial tax authority (MRQ) and various state tax authorities. We do not believe that resolution of these controversies will have a material impact on our financial position or results of operations.

We are challenging the reassessments received by the CRA with respect to the SR&ED credits claimed in 2003 and 2004 by our Canadian Preclinical Services subsidiary in the Tax Court of Canada (TCC). Additionally, we filed Notices of Objection in response to Notices of Reassessment received from the MRQ with respect to our 2003 and 2004 claims for the Quebec Research and Development tax credits. We disagree with the positions taken by the CRA and MRQ with regard to the credits claimed. We believe that it is reasonably possible that we will conclude the controversies with the TCC and MRQ within the next twelve months. We do not believe that resolution of these controversies will have a material impact on our financial position or results of operations. However, it is possible that the CRA and MRQ will propose similar adjustments for later years.

We believe we have appropriately provided for all uncertain tax positions.

In accordance with our policy, the undistributed earnings of our non-U.S. subsidiaries remain indefinitely reinvested as of the end of the first quarter of 2012 as they are required to fund needs outside the U.S. and cannot be repatriated in a manner that is substantially tax free.

17

CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

NOTES TO UNAUDITED CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS (Continued)

(dollars in thousands, except per share amounts)

For the three months ended March 31, 2012, income tax expense of $261 related to items of other comprehensive income included a $89 benefit related to foreign currency translation adjustments and $350 of tax expenses related to the change in unrecognized pension gains, losses and prior service costs. For the three months ended March 26, 2011, income tax expense of $204 related to items of other comprehensive income included $66 related to foreign currency translation adjustments and $138 related to the change in unrecognized pension gains, losses and prior service costs.

10. Employee Benefits

The following table provides thecomponents of net periodic benefit cost for our defined benefit plans:

	Pension Benefits						Supplemental Retirement Benefits
	March 31, 2012			March 26, 2011			March 31, 2012		March 26, 2011
Service cost	$	979		$	766		$	160	$	159
Interest cost	2,811			3,022			223		300
Expected return on plan assets	(3,430		)	(3,388		)	—		—
Amortization of prior service cost (credit)	(151		)	(154		)	165		125
Amortization of net loss (gain)	582			239			65		53
Net periodic benefit cost	791			485			613		637
Company contributions	$	5,685		$	3,591		$	—	$	—

During 2012, we expect to contribute $13,868 to our pension plans.

11. Stock Plans and Stock Based Compensation

The estimated fair value of our stock-based awards, less expected forfeitures, is amortized over the awards' vesting period on a straight-line basis. The following table presents stock-based compensation included in our consolidated statement of income:

	March 31, 2012			March 26, 2011
Stock-based compensation expense included in:
Cost of sales	$	1,448		$	1,678
Selling and administration	3,818			4,241
Stock-based compensation, before income taxes	5,266			5,919
Provision for income taxes	(1,884		)	(2,119		)
Stock-based compensation, net of tax	$	3,382		$	3,800

The fair value of stock-based awards granted during the first three months of 2012 and 2011 was estimated on the grant date using the Black-Scholes option-pricing model with the following weighted-average assumptions:

	March 31, 2012			March 26, 2011
Expected life (in years)	4.5			4.2
Expected volatility	35.0		%	33.5		%
Risk-free interest rate	0.84		%	2.23		%
Expected dividend yield	0		%	0		%
Weighted-average grant date fair value	$	11.02		$	11.29

18

CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

NOTES TO UNAUDITED CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS (Continued)

(dollars in thousands, except per share amounts)

Stock Options

The following table summarizes stock option activities under our plans:

	Shares		Weighted Average Exercise Price		Weighted Average Remaining Contractual Life (in years)	Aggregate Intrinsic Value
Options outstanding as of December 31, 2011	6,081,263		$	38.25
Options granted	543,065		$	36.25
Options exercised	(108,147	)	$	25.10
Options canceled	(84,662	)	$	39.85
Options outstanding as of March 31, 2012	6,431,519		$	38.28	3.71 years	$	14,757
Options exercisable as of March 31, 2012	4,374,304		$	39.78	2.83 years	$	10,842

As of March 31, 2012, the unrecognized compensation cost related to 2,057,215 unvested stock options expected to vest was $18,792. This unrecognized compensation will be recognized over an estimated weighted-average amortization period of 32 months.

The total intrinsic value of options exercised during the three months ending March 31, 2012 and March 26, 2011 was $1,131 and $2,128, respectively, with intrinsic value defined as the difference between the market price on the date of exercise and the grant date price. The total amount of cash received from the exercise of options during the three months ending March 31, 2012 and March 26, 2011 was $2,715 and $5,239, respectively. The actual tax benefit realized for the tax deductions from option exercises totaled $374 for the three months ending March 31, 2012. A charge of $5 was recorded in capital in excess of par value in the first quarter for the excess of deferred tax assets over the actual tax benefits at option exercise. We settle stock option exercises with newly issued common shares.

Restricted Stock

Stock compensation expense associated with restricted common stock is charged for the market value on the date of grant, less estimated forfeitures, and is amortized over the awards' vesting period on a straight-line basis.

The following table summarizes the restricted stock activity for the three months ending March 31, 2012:

	Restricted Stock		Weighted Average Grant Date Fair Value
Outstanding as of December 31, 2011	703,011		$	35.70
Granted	499,360		36.25
Vested	(260,173	)	36.10
Canceled	(12,005	)	35.89
Outstanding as of March 31, 2012	930,193		$	35.61

As of March 31, 2012, the unrecognized compensation cost related to shares of unvested restricted stock expected to vest was $28,821. This unrecognized compensation will be recognized over an estimated weighted-average amortization period of 38 months. The total fair value of restricted stock grants that vested during the fiscal years ending March 31, 2012 and March 26, 2011 was $9,392 and $10,136, respectively. The actual tax benefit realized for the tax deductions from restricted stock grants that vested totaled $3,346 for the three months ended March 31, 2012.

Performance Based Stock Award Program

Compensation expense associated with performance-based stock awards of $(27) and $54 has been recorded during the three months ended March 31, 2012 and March 26, 2011, respectively.

19

CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

NOTES TO UNAUDITED CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS (Continued)

(dollars in thousands, except per share amounts)

12. Commitments and Contingencies

Various lawsuits, claims and proceedings of a nature considered normal to our business are pending against us. In the opinion of management, the outcome of such proceedings and litigation currently pending will not materially affect our consolidated financial statements.

On January 31, 2012, a putative class action, entitled Irma Garcia v. Charles River Laboratories, Inc., was filed against us in the San Diego Superior Court, alleging various causes of action related to failure to make proper and timely payments to employees in California, failure to timely furnish accurate itemized wage statements, unfair business practices, associated penalties pursuant to California law, and declaratory relief. While no prediction may be made as to the outcome of litigation, we intend to defend against this proceeding vigorously and therefore an estimate of the possible loss or range of loss cannot be made.

13. Business Segment Information

We report two business segments, Research Models and Services (RMS) and Preclinical Services (PCS). Our RMS segment includes sales of research models, genetically engineered models and services (GEMS), insourcing solutions (IS), research animal diagnostic services (RADS), discovery services (DS), in vitro products, and avian vaccine products and services. Our PCS segment includes services required to take a drug through the development process, which include discovery support, safety assessment and biopharmaceutical services.

The following table presents sales and other financial information by business segment.

	Three Months Ended
	March 31, 2012		March 26, 2011
Research Models and Services
Net sales	$	183,152	$	173,371
Gross margin	82,196		73,839
Operating income	59,467		51,742
Depreciation and amortization	8,942		9,269
Capital expenditures	12,900		4,403
Preclinical Services
Net sales	$	102,829	$	112,472
Gross margin	22,016		28,799
Operating income	4,174		9,306
Depreciation and amortization	11,060		11,996
Capital expenditures	1,211		2,387

A reconciliation of segment operating income to consolidated operating income is as follows:

	Three Months Ended
	March 31, 2012			March 26, 2011
Total segment operating income	$	63,641		$	61,048
Unallocated corporate overhead	(19,901		)	(18,797		)
Consolidated operating income	$	43,740		$	42,251

20

CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

NOTES TO UNAUDITED CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS (Continued)

(dollars in thousands, except per share amounts)

Net sales for each significant service area are as follows:

	Three Months Ended
	March 31, 2012		March 26, 2011
Research models	$	94,021	$	93,400
Research model services	56,331		51,975
Other products	32,800		27,996
Total research models	183,152		173,371
Total preclinical services	102,829		112,472
Total sales	$	285,981	$	285,843

A summary of unallocated corporate overhead consists of the following:

	Three Months Ended
	March 31, 2012		March 26, 2011
Stock-based compensation expense	$	2,785	$	2,986
U.S. retirement plans	1,372		1,057
Audit, tax and related expense	654		755
Salary and bonus	4,923		4,693
Global IT	2,850		2,993
Employee health, long-term disability and fringe benefit expense	1,993		1,639
Consulting and professional services	1,742		1,331
Depreciation expense	1,569		1,581
Other general unallocated corporate expenses	2,013		1,762
Total unallocated corporate overhead costs	$	19,901	$	18,797

Other general unallocated corporate expenses consist of various departmental costs including those associated with departments such as senior executives, corporate accounting, legal, tax, human resources, treasury and investor relations.

14. Discontinued Operations

On March 28, 2011, we disposed of our Phase I clinical business for a nominal amount. As part of the disposition we remained the guarantor of the Phase I facility lease. During the second quarter of 2011, we recognized the value of the guarantee net of the buyer's related indemnity as a liability of $2,994, which we are accreting ratably over the remaining term of the lease. The facility lease runs through January 2021 with remaining lease payments totaling $14,351 as of March 31, 2012.

The consolidated financial statements have been reclassified to segregate, as discontinued operations, the assets and liabilities, operating results and cash flows, of the businesses being discontinued for all periods presented. Operating results from discontinued operations are as follows:

21

CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

NOTES TO UNAUDITED CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS (Continued)

(dollars in thousands, except per share amounts)

	Three Months Ended
	March 31, 2012		March 26, 2011
Net sales	$	—	$	2,112
Income (loss) from operations of discontinued businesses, before income taxes	104		(5,202		)
Provision (benefit) for income taxes	27		(1,257		)
Income (loss) from operations of discontinued businesses, net of taxes	$	77	$	(3,945	)

Assets and liabilities of discontinued operations at March 31, 2012 and December 31, 2011 consisted of the following:

	March 31, 2012		December 31, 2011
Current assets	$	107	$	107
Long-term assets	959		986
Total assets	$	1,066	$	1,093
Current liabilities	$	1,164	$	1,165
Long-term liabilities	2,452		2,522
Total liabilities	$	3,616	$	3,687

Current assets and non-current assets include a short-term and long-term deferred tax asset related to lease guarantee. Current and long-term liabilities consist of the carrying value of the lease guarantee and accrued expenses.

22

Item 7.    Management's Discussion and Analysis of Financial Condition and Results of Operations

The following Management's Discussion and Analysis will help you understand our financial condition and results of operations. The Management's Discussion and Analysis is a supplement to, and should be read in conjunction with, our consolidated financial statements and the accompanying notes to the consolidated financial statements.

Overview

We are a leading global provider of solutions that advance the drug discovery and development process, including research models and associated services and outsourced preclinical services. We provide our products and services to global pharmaceutical companies and biotechnology companies, as well as government agencies, leading hospitals and academic institutions throughout the world in order to bring drugs to market faster and more efficiently. We have built upon our core competency of in vivo biology, including laboratory animal medicine and science (research model technologies) to develop a diverse portfolio of preclinical services - both GLP (Good Laboratory Practice) and non-GLP - which address drug discovery and development. Utilizing our broad portfolio of products and services enables our clients to create a more flexible drug development model which reduces their costs, enhances their productivity and effectiveness, and increase speed to market. We have been in business for 65 years and currently operate approximately 64 facilities in 15 countries worldwide.

Large pharmaceutical and biotechnology companies have been undergoing significant change in recent years as they endeavor to improve the productivity of their drug development pipelines, and at the same time, streamline their infrastructures in order to improve efficiency and reduce operating costs. These efforts have had an unfavorable impact on our operations as a result of: measured research and development spending by major pharmaceutical and biotechnology companies; delays in customer decisions and commitments; tight cost constraints and the resultant pricing pressure, particularly in view of excess capacity in the contract research industry; a focus on late-stage clinical testing as customers accelerate their efforts to bring drugs to market in the face of expiration of patents on branded drugs; decreased funding for biopharmaceutical companies; and the impact of healthcare reform initiatives. In addition, consolidation in the pharmaceutical and biotechnology industry has affected demand for our products and services. All of these ongoing factors continue to contribute to demand uncertainty and are expected to impact future sales.

Our market for goods and services appears to continue to stabilize but we remain uncertain as to when the unfavorable market factors will abate. As part of our clients' efforts to improve pipeline productivity, pharmaceutical and biotechnology companies are emphasizing efficacy testing in order to eliminate therapies from the pipeline earlier in the drug development process. This trend is visible in increasing demand for our non-GLP in vivo pharmacology and drug metabolism and pharmacokinetics services. We continue to anticipate that our clients will reduce their internal capacity through closure of underutilized facilities and increase their use of these outsourced services in the future, because utilizing outsourced services enables them to create a flexible drug development model which improves operating efficiency and reduces costs. We believe that increased focus on strategic outsourcing by our clients should result in the expansion of strategic relationships with a reduced and limited number of partners, which will drive demand for our services. We believe that the long-term drivers for our business as a whole will primarily emerge from our clients' continued demand for research models and services and both GLP and non-GLP in vivo biology services, which are essential to the drug development process. However, presently it is challenging to predict the timing associated with these drivers.

We continue to focus on our four key initiatives designed to allow us to drive profitable growth and to maximize value for shareholders, and thus better position ourselves to operate successfully in the current and future business environment. These four initiatives are:

• Improving the consolidated operating margin. We continue to aggressively manage our cost structure and drive operating efficiencies, which are expected to generate improvement in our operating margins. We have already implemented significant actions to reduce costs during the last two years to manage challenging industry-wide preclinical market conditions. During the first quarter of 2012 we continued to selectively adjust our cost structure by headcount reductions and other cost initiatives.

• Improving free cash flow generation. We believe we have adequate capacity to support revenue growth in both business segments without significant additional investment for expansion. Capital expenditures were $14.1 million in the first quarter of 2012 and we expect capital expenditures to be approximately $50.0 million for this year.

• Disciplined investment in growth businesses. We continue to maintain a disciplined focus on deployment of capital, investing in those areas of our existing business which will generate the greatest sales growth and profitability, such as Genetically Engineered Models and Services (GEMS), Discovery Services (DS) and In Vitro products.

23

• Returning value to shareholders. We are repurchasing our stock with the intent to drive immediate shareholder value and earnings per share accretion. During the first quarter of 2012 and 2011, we repurchased 0.4 million and 8.4 million shares, respectively. Our weighted average shares outstanding for the first quarter of 2012 has decreased to 48.8 million shares from 54.6 million shares for the first quarter of 2011.

Total net sales during the first quarter of 2012 were $286.0 million, an increase of 0.1% over the same period last year. The sales increase was due primarily to increased sales for RMS segment partially offset by lower PCS sales. The effect of foreign currency translation had a negative impact on sales of 0.9%. Our gross margin increased to 36.4% of net sales for the first quarter of 2012 compared to 35.9% of net sales for the first quarter of 2011, due primarily to cost savings actions and the impact of increased RMS segment sales. Our operating income was $43.7 million for the first quarter of 2012 compared to operating income of $42.3 million for the first quarter of 2011, an increase of 3.3% due to strong Research Model Services segment. Operating margin was 15.3% for the first quarter of 2012, compared to14.8% for the first quarter of 2011.

Our net income attributable to common shareholders was $26.4 million for the three months ended March 31, 2012 compared to $31.3 million for the three months ended March 26, 2011. The decrease was primarily due to the tax benefit in 2011 related to the disposition of our Phase I clinical business. Diluted earnings per share for the first quarter of 2012 was $0.54 compared to diluted earnings per share of $0.57 for the first quarter of 2011.

We report two segments: Research Models and Services (RMS) and Preclinical Services (PCS), which reflects the manner in which our operating units are managed.

Our RMS segment, which represented 64.0% of net sales in the first quarter of 2012, includes three categories: production of research models, Research Model Services, and Other Products. Research Model Services include four business units: Genetically Engineered Models and Services (GEMS), Research Animal Diagnostics (RADS), Discovery Services (DS), and Insourcing Solutions (IS). Other Products includes our In Vitro business and avian vaccine services. Net sales for the RMS segment increased 5.6% compared to the first quarter of 2011, primarily driven by higher sales of Other Products and Research Model Services. The effect of foreign currency translation had a negative impact on sales of 0.9%. Gross margin percentage increased to 44.9% from 42.6% due to primarily to cost savings actions and our fixed cost leverage with increased sales. Operating margin percentage increased to 32.5% from 29.8% .

Our PCS segment, which represented 36.0% of net sales in the first quarter of 2012, includes services required to take a drug through the development process including discovery support, safety assessment and biopharmaceutical services. Sales for this segment decreased 8.6% from the first quarter of 2011, as a result of a greater proportion of non-GLP discovery research services combined with lower biopharmaceutical services sales. Foreign currency translation reduced the sales growth rate by 1.0%. We experienced a decrease in the PCS gross margin to 21.4% from 25.6% in the first quarter of 2011. Operating margin for the first quarter of 2012 was 4.1% , compared to 8.3% in the first quarter of 2011, due mainly to a reduction in profitability for the biopharmaceutical services.

Three Months EndedMarch 31, 2012 Compared to the Three Months EndedMarch 26, 2011

Net Sales. Net sales for the three months ended March 31, 2012 were $286.0 million, an increase of $0.2 million, or 0.1%, from $285.8 million for the three months ended March 26, 2011, due primarily to increased sales for RMS partially offset by lower PCS sales and unfavorable foreign currency translation of 0.9% .

Research Models and Services. For the three months ended March 31, 2012, net sales for our RMS segment were $183.2 million, an increase of $9.8 million, or 5.6%, from $173.4 million for the three months ended March 26, 2011, due primarily to higher Other Product sales, which include our Avian and In Vitro businesses, as well as Research Model Services. The effect of unfavorable foreign currency translation decreased sales by 0.9%.

Preclinical Services. For the three months ended March 31, 2012, net sales for our PCS segment were $102.8 million, a decrease of $9.7 million, or 8.6%, from $112.5 million for the three months ended March 26, 2011. The sales decrease was driven by unfavorable sales mix with a greater proportion of non-GLP discovery services, as well as lower sales of biopharmaceutical services combined with unfavorable foreign currency translation of 1.0%.

Cost of Products Sold and Services Provided. Cost of products sold and services provided during the first quarter of 2012 was $181.8 million, a decrease of $1.4 million, or 0.8%, from $183.2 million during the first quarter of 2011. Cost of products sold and services provided during the three months ended March 31, 2012 was 63.6% of net sales, compared to 64.1% during the three months ended March 26, 2011.

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Research Models and Services. Cost of products sold and services provided for RMS during the first quarter of 2012 was $101.0 million, an increase of $1.5 million, or 1.4%, compared to $99.5 million in 2011. Cost of products sold and services provided for the three months ended March 31, 2012 decreased to 55.1% of net sales compared to 57.4% of net sales for 2011. The decrease in cost as a percentage of sales was primarily due to the impact increased sales and our cost-savings actions.

Preclinical Services. Cost of services provided for the PCS segment the first quarter of 2012 was $80.8 million, a decrease of $2.9 million, compared to $83.7 million in 2011. Cost of services provided as a percentage of net sales was 78.6% during the three months ended March 31, 2012, compared to 74.4% for the three months ended March 26, 2011. The increase in cost of services provided as a percentage of net sales was primarily due to the impact of lower sales on our fixed costs base.

Selling, General and Administrative Expenses. Selling, general and administrative expenses for the three months ended March 31, 2012 were $56.0 million, an increase of $1.0 million, or 1.8%, from $55.0 million for the three months ended March 26, 2011. Selling, general and administrative expenses the first quarter of 2012 were 19.6% of net sales compared to 19.2% for the first quarter of 2011.

Research Models and Services. Selling, general and administrative expenses for RMS for the first quarter of 2012 were $21.2 million, an increase of $0.8 million, or 4.1%, compared to $20.4 million in 2011. Selling, general and administrative expenses decreased as a percentage of sales to 11.6% for the three months ended March 31, 2012 from 11.8% for the three months ended March 26, 2011. The decrease in selling, general and administrative expenses as a percent of sales was primarily due to cost-savings actions and increased sales.

Preclinical Services. Selling, general and administrative expenses for the PCS segment for the first quarter of 2012 were $14.8 million, a decrease of $1.0 million, or 6.2%, compared to $15.8 million during 2011. Selling, general and administrative expenses for the three months ended March 31, 2012 increased to 14.4% of net sales, compared to 14.1% of net sales for the three months ended March 26, 2011, due mainly to the lower sales.

Unallocated Corporate Overhead. Unallocated corporate overhead, which consists of various costs primarily associated with activities centered at our corporate headquarters, such as compensation (including stock-based compensation), information systems, compliance and facilities expenses associated with our corporate, administration and professional services functions, was $19.9 million during the three months ended March 31, 2012, compared to $18.8 million during the three months ended March 26, 2011.The increase was primarily due to increased compensation, fringe related costs, and consulting in 2012.

Amortization of Other Intangibles. Amortization of other intangibles for the three months ended March 31, 2012 was $4.5 million, a decrease of $0.9, from $5.4 million for the three months ended March 26, 2011. Amortization expense decreased as a percentage of sales to 1.6% for the three months ended March 31, 2012, from 1.9% for the three months ended March 26, 2011.

Research Models and Services. In the first quarter of 2012, amortization of other intangibles for our RMS segment was $1.5 million, a decrease of $0.2 million from $1.7 million in the first quarter of 2011.

Preclinical Services. For the three months ended March 31, 2012, amortization of other intangibles for our PCS segment was $3.0 million, a decrease of $0.7 million from $3.7 million for the three months ended March 26, 2011.

Operating Income. Operating income for the three months ended March 31, 2012 was $43.7 million, an increase of $1.4 million compared to operating income of $42.3 million for the three months ended March 26, 2011. Operating income as a percentage of net sales for the three months ended March 31, 2012 was 15.3% compared to 14.8% for the three months ended March 26, 2011.

Research Models and Services. For the three months ended March 31, 2012, operating income for our RMS segment was $59.5 million, an increase of $7.8 million, or 14.9%, from $51.7 million in 2011. Operating income as a percentage of net sales for the three months ended March 31, 2012 was 32.5%, compared to 29.8% for the three months ended March 26, 2011. The increase in operating income as a percentage of net sales was primarily due to increased sales and cost-savings actions.

Preclinical Services. For the the three months ended March 31, 2012, operating income for our PCS segment was $4.2 million, a decrease of $5.1 million compared to $9.3 million for the three months ended March 26, 2011. Operating income as a percentage of net sales declined to 4.1% compared to 8.3% of net sales in 2011. The decrease in operating income as a percentage of net sales was primarily due to lower sales and the reduction in profitability for our biopharmaceutical services.

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Unallocated Corporate Overhead. Unallocated corporate overhead was $19.9 million during the three months ended March 31, 2012, compared to $18.8 million during the three months ended March 26, 2011. The increase was primarily due to increased compensation, fringe related costs, and consulting in 2012.

Interest Expense. Interest expense the first quarter of 2012 was $8.4 million, compared to $10.0 million in the first quarter of 2011. The decrease was due mainly to decreased debt balances and lower interest rates.

Interest Income. Interest income for the first quarter of 2012 was $0.2 million, compared to $0.4 million for the first quarter of 2011.

Income Taxes. Income tax expense for the three months ended March 31, 2012 was $8.7 million, an increase of $11.4 million compared to a benefit of $2.7 million for the three months ended March 26, 2011. Our effective tax rate was 24.7% for the first quarter of 2012 compared to a tax benefit of 8.3% for the first quarter of 2011. The increase in the effective tax rate for the three months ended March 31, 2012 was primarily due to the recognition of an $11.1 million tax benefit from the tax loss on the disposition of the our Phase I clinical business in 2011 and the unbenefitted capital loss of $0.7 million on the sale of our auction rate securities incurred in the first quarter of 2012.

Net Income Attributable to Common Shareowners. Net income attributable to common shareowners for the three months ended March 31, 2012 was $26.4 million compared to $31.3 million for the three months ended March 26, 2011.

Liquidity and Capital Resources

The following discussion analyzes liquidity and capital resources by operating, investing and financing activities as presented in our consolidated statements of cash flows.

Our principal sources of liquidity have been our cash flow from operations, our marketable securities and our revolving line of credit arrangements.

Our credit agreement dated September 23, 2011 provides for a $299.8 million term loan, a €69.4 million Euro term loan and a $350.0 million revolving credit facility. The term loan facility matures in 20 quarterly installments with the last installment due September 23, 2016. The $350 million revolving facility also matures on September 23, 2016 and requires no scheduled payment before that date. The book value of our term and revolving loans approximates fair value.

The credit agreement includes certain customary representations and warranties, events of default, notices of material adverse changes to our business and negative and affirmative covenants. As of March 31, 2012, we were compliant with all financial covenants specified in the credit agreement. We had $4.3 million outstanding under letters of credit as of March 31, 2012.

Our debt also includes $350.0 million of 2.25% Senior Convertible Debentures (2013 Notes) due June 2013. At March 31, 2012, the fair value of our outstanding 2013 Notes was approximately $354.2 million based on their quoted market value and no conversion triggers were met. Upon maturity, we will settle the principal balance of the 2013 Notes in cash and any additional amount due to the conversion feature in cash or shares. We intend to utilize our existing cash and marketable securities, future cash flow from operations, existing capacity of our credit agreement, which includes possible increases to term and/or revolving line of credit, and evaluate other financing alternatives, to meet the cash requirement at maturity in June 2013.

In accordance with our policy, the undistributed earnings of our non-U.S. subsidiaries remain indefinitely reinvested as of the end of the first quarter of 2012 as they are required to fund needs outside the U.S. and cannot be repatriated in a manner that is substantially tax free.

For the three months ended March 31, 2012, we repurchased 348.0 thousand shares of common stock for $12.5 million through open market purchases made in reliance on Rule 10b-18. The timing and amount of any future repurchases will depend on market conditions and corporate considerations.

As of March 31, 2012, we had $6.1 million in time deposits classified as marketable securities. During the period ended March 31, 2012, we sold our auction rate securities for $11.3 million in cash and recorded a realized loss of $0.7 million, which is included in other income (expense). The March 31, 2012 balance of marketable securities was comprised of $6.1 million held by non-U.S. subsidiaries.

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Cash and cash equivalents totaled $61.0 million at March 31, 2012, compared to $68.9 million at December 31, 2011. The decline in cash and cash equivalents was primarily due to the repurchase of shares, capital expenditures and prepayment of debt. At March 31, 2012, the $61.0 million was comprised of $3.7 million held in the United States and $57.3 million held by non-U.S. subsidiaries. At December 31, 2011, the $68.9 million was comprised of $0.4 million held in the United States and $68.5 million held by non-U.S. subsidiaries. We are a net borrower and closely manage our cash to keep balances low. We were able to maintain liquidity by having the ability to borrow on our revolving line of credit.

Net cash provided by operating activities for the quarters ending March 31, 2012 and March 26, 2011 was $25.3 million and $21.4 million, respectively. The increase in cash provided by operations was primarily due to stable deferred revenue in the quarter ending March 31, 2012 compared to a decrease in deferred revenue for the quarter ending March 26, 2011. The tax benefit related to the disposition of our Phase I clinical business, which increased net income in 2011, will be realized in cash in the future. Our days sales outstanding (DSO) remained flat at 48 days as of March 31, 2012 compared December 31, 2011 but decreased from 49 days as of March 26, 2011. Our DSO includes deferred revenue as an offset to accounts receivable in the calculation. Our net cash provided by operating activities will be impacted by future timing of client payments for products and services as evidenced in our DSO. A one-day increase or decrease in our DSO represents a change of approximately $3.1 million of cash provided by operating activities. Our allowance for doubtful accounts was $4.5 million as of March 31, 2012 compared to $4.0 million as of December 31, 2011.

Net cash used in investing activities for the quarters ending March 31, 2012 and March 26, 2011 was $3.3 million and $12.5 million, respectively. Our capital expenditures during the first quarter of 2012 were $14.1 million, of which $12.9 million was related to RMS and $1.2 million to PCS. For 2012, we project capital expenditures to be approximately $50.0 million. We anticipate that future capital expenditures will be funded by operating activities, marketable securities and existing credit facilities. For the quarters ending March 31, 2012 and March 26, 2011, we sold $14.6 million and $3.7 million of marketable securities, respectively.

Net cash used in financing activities for the quarters ending March 31, 2012 and March 26, 2011 was $30.6 million and $29.3 million, respectively. Proceeds from long-term debt were $28.0 million and $150.6 million for the quarters ending March 31, 2012 and March 26, 2011, respectively. Payments on long-term debt and revolving credit agreements were $46.6 million and $9.8 million for the quarters ending March 31, 2012 and March 26, 2011, respectively. For the quarters ending March 31, 2012 and March 26, 2011, we paid $15.2 million and $174.5 million, respectively, for the purchase of treasury stock acquired through open market purchases and the accelerated share repurchase program in 2011.

Off-Balance Sheet Arrangements

The conversion features of our 2013 Notes are equity-linked derivatives. As such, we recognize these instruments as off-balance sheet arrangements. Because the conversion features associated with these notes are indexed to our common stock and classified in stockholders' equity, these instruments are not accounted for as derivatives.

Recent Accounting Pronouncements

In May 2011, the FASB issued an accounting standard update to require disclosure of information about fair value measurements. This amendment was effective for us on January 1, 2012 and was applied prospectively.

In June 2011, the FASB issued an accounting standard update that increases the prominence of items reported in other comprehensive income, eliminates the option to present components of other comprehensive income as part of the statement of changes in stockholders' equity, and requires that all non-owner changes in stockholders' equity be presented either in a single continuous statement of comprehensive income or in two separate but consecutive statements. We elected the two-statement approach, where the first statement presents total net income and its components, followed consecutively by a second statement that presents total other comprehensive income, the components of other comprehensive income, net of tax effects, and total of comprehensive income. This amendment was effective for us on January 1, 2012 and was applied retrospectively.

In September 2011, The FASB issued an accounting standard update related to the goodwill impairment test. The revised standard is intended to reduce the cost and complexity of the annual goodwill impairment test by providing companies with the option of performing a qualitative assessment to determine whether future impairment testing is necessary. The revised standard was effective for us on January 1, 2012 and will be applied prospectively.

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Item 3.    Quantitative and Qualitative Disclosures about Market Risk

Certain of our financial instruments are subject to market risks, including interest rate risk and foreign currency exchange rates. We generally do not use financial instruments for trading or other speculative purposes.

Interest Rate Risk

We entered into our amended credit agreement on September 23, 2011. Our primary interest rate exposure results from changes in LIBOR or the base rates which are used to determine the applicable interest rates under our term loans and revolving credit facility in the credit agreement.

        Our potential additional interest expense over one year that would result from a hypothetical, instantaneous and unfavorable change of 100 basis points in the interest rate would be approximately $6.8 million on a pre-tax basis. The book value of our debt approximates fair value.

        We issued $350.0 million of the 2013 Notes in a private placement in the second quarter of 2006. The 2013 Notes bear an interest rate of 2.25%. The fair market value of the outstanding notes was approximately $354.2 million on March 31, 2012.

Foreign Currency Exchange Rate Risk

        We operate on a global basis and have exposure to some foreign currency exchange rate fluctuations for our earnings and cash flows. This risk is mitigated by the fact that various foreign operations are principally conducted in their respective local currencies. A portion of the revenue from our foreign operations is denominated in U.S. dollars, with the costs accounted for in their local currencies. Additionally, we have exposure on certain intercompany loans. We attempt to minimize this exposure by using certain financial instruments, for purposes other than trading, in accordance with our overall risk management and our hedge policy. In accordance with our hedge policy, we designate such transactions as hedges.

        During the first quarter of 2012, we utilized foreign exchange contracts, principally to hedge the impact of currency fluctuations on client transactions and certain balance sheet items, including intercompany loans. The foreign currency contract outstanding as of March 31, 2012 is a non-designated hedge, and is marked to market with changes in fair value recorded to other income (expense).

Item 4.    Controls and Procedures

(a)   Evaluation of Disclosure Controls and Procedures

Based on their evaluation, required by paragraph (b) of Rules 13a-15 or 15d-15, promulgated by the Securities Exchange Act of 1934 (Exchange Act), the Company's principal executive officer and principal financial officer have concluded that the Company's disclosure controls and procedures as defined in Rules 13a-15(e) and 15d-15(e) of the Exchange Act are effective, at a reasonable assurance level, as of March 31, 2012 to ensure that information required to be disclosed by the Company in reports that it files or submits under the Exchange Act is recorded, processed, summarized and reported within the time periods specified in Securities and Exchange Commission rules and forms. Disclosure controls and procedures include, without limitation, controls and procedures designed to ensure that information required to be disclosed by an issuer in the reports that it files or submits under the Exchange Act is accumulated and communicated to the issuer's management, including its principal executive and principal financial officers, or persons performing similar functions, as appropriate to allow timely decisions regarding required disclosure. In designing and evaluating the disclosure controls and procedures, our management recognized that any controls and procedures, no matter how well designed and operated, can provide only reasonable assurances of achieving the desired control objectives, and management necessarily was required to apply its judgment in designing and evaluating the controls and procedures. We continually are in the process of further reviewing and documenting our disclosure controls and procedures, and our internal control over financial reporting, and accordingly may from time to time make changes aimed at enhancing their effectiveness and to ensure that our systems evolve with our business.

(b) Changes in Internal Controls

There were no changes in the Company's internal controls over financial reporting identified in connection with the evaluation required by paragraph (d) of the Exchange Act Rules 13a-15 or 15d-15 that occurred during the quarter ended March 31, 2012 that materially affected, or were reasonably likely to materially affect, the Company's internal control over financial reporting.

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PART II

Item 1A. Risk Factors

In addition to the other information set forth in this report, you should carefully consider the factors discussed in Part I, “Item 1A. Risk Factors” in our Annual Report on Form 10-K for the year ended December 31, 2011, which could materially affect our business, financial condition or future results. The risks described in our Annual Report on Form 10-K are not the only risks facing us. Additional risks and uncertainties not currently known to us or that we currently deem to be immaterial also may materially adversely affect our business, financial condition and/or operating results. There have been no material changes to the risk factors set forth in our Annual Report on Form 10-K for the year ended December 31, 2011.

Item 2.    Unregistered Sales of Equity Securities and Use of Proceeds

The following table provides information relating to the our purchases of shares of our common stock during the quarter ended March 31, 2012.

	Total Number of Shares Purchased	Average Price Paid per Share		Total Number of Shares Purchased as Part of Publicly Announced Plans or Programs	Approximate Dollar Value of Shares That May Yet Be Purchased Under the Plans or Programs
January 1, 2012 to January 28, 2012	—	—		—	$	116,258
January 29, 2012 to February 25, 2012	56,962	$	35.40	56,962	$	114,242
February 26, 2012 to March 31, 2012	373,381	$	36.03	291,006	$	103,758
Total:	430,343			347,968

On July 29, 2010, our Board of Directors authorized a $500.0 million stock repurchase program. Our Board of Directors increased the stock repurchase authorization by $250.0 million to $750.0 million on October 20, 2010.

During the first quarter of 2012, we repurchased 347,968 shares of common stock for $12.5 million under our Rule 10b5-1 Purchase Plan and in open market trading.

Additionally, the Company's Incentive Plans permit the netting of common stock upon vesting of restricted stock awards in order to satisfy individual tax withholding requirements. Accordingly, during the period ended March 31, 2012, we acquired 82,375 shares for a nominal amount as a result of such withholdings.

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Item 6.    Exhibits

(a) Exhibits

31.1    Rule 13a-14(a)/15d-14(a) Certification of Chief Executive Officer. Filed herewith.

31.2    Rule 13a-14(a)/15d-14(a) Certification of Chief Financial Officer. Filed herewith.

32.1 Certification of the Principal Executive Officer and the Principal Financial Officer required by Rule 13a-14(a) of 15d-14(a) of the Exchange Act. Filed herewith.

101 The following materials from the Form 10-Q for the year period ended March 31, 2012 formatted in XBRL (eXtensible Business Reporting Language): (i) the Condensed Consolidated Statements of Operations, (ii) the Condensed Consolidated Statements of Comprehensive Income , (iii) the Condensed Consolidated Balance Sheets, (iv) the Condensed Consolidated Statements of Shareholders' Equity, (v) the Condensed Consolidated Statements of Cash Flows, and (vi) related notes to these Unaudited, Condensed Consolidated Interim Financial Statements.

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SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

	CHARLES RIVER LABORATORIES INTERNATIONAL, INC.
May 4, 2012	/s/ JAMES C. FOSTER
	James C. Foster Chairman, President and Chief Executive Officer

May 4, 2012	/s/ THOMAS F. ACKERMAN
	Thomas F. Ackerman Corporate Executive Vice President and Chief Financial Officer

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Exhibit 31.1

CERTIFICATION PURSUANT TO

SECTION 302 OF THE SARBANES‑OXLEY ACT OF 2002

AND RULE 13a-14(a)/15d-14(a) OF THE EXCHANGE ACT OF 1934

I, James C. Foster, Chief Executive Officer of Charles River Laboratories International, Inc. (the registrant) certify that:

1. I have reviewed this quarterly report on Form 10-Q for the quarter ended March 31, 2012 of the registrant;

2. Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;

3. Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report;

4. The registrant's other certifying officers and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the registrant and have:

a. designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this report is being prepared;

b. designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles;

c. evaluated the effectiveness of the registrant's disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures as of the end of the period covered by this report based on such evaluation; and

d. disclosed in this report any change in the registrant's internal control over financial reporting that occurred during the registrant's most recent fiscal quarter (the registrant's fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect, the registrant's internal control over financial reporting; and

5. The registrant's other certifying officers and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the registrant's auditors and the audit committee of registrant's board of directors (or persons performing the equivalent functions):

a. all significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the registrant's ability to record, process, summarize and report financial information; and

b. any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant's internal control over financial reporting.

Dated: May 4, 2012 /s/ James C. Foster James C. Foster Chairman, President and Chief Executive Officer Charles River Laboratories International, Inc.

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Exhibit 31.2

CERTIFICATION PURSUANT TO

SECTION 302 OF THE SARBANES‑OXLEY ACT OF 2002

AND RULE 13a-14(a)/15d-14(a) OF THE EXCHANGE ACT OF 1934

I, Thomas F. Ackerman, Corporate Executive Vice President and Chief Financial Officer of Charles River Laboratories International, Inc. (the registrant) certify that:

1. I have reviewed this quarterly report on Form 10-Q for the quarter ended March 31, 2012 of the registrant;

2. Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;

3. Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report;

4. The registrant's other certifying officers and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the registrant and have:

a. designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this report is being prepared;

b. designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles;

c. evaluated the effectiveness of the registrant's disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures as of the end of the period covered by this report based on such evaluation; and

d. disclosed in this report any change in the registrant's internal control over financial reporting that occurred during the registrant's most recent fiscal quarter (the registrant's fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect, the registrant's internal control over financial reporting; and

5. The registrant's other certifying officers and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the registrant's auditors and the audit committee of registrant's board of directors (or persons performing the equivalent functions):

a. all significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the registrant's ability to record, process, summarize and report financial information; and

b. any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant's internal control over financial reporting.

Dated: May 4, 2012 /s/ Thomas F. Ackerman Thomas F. Ackerman Corporate Executive Vice President and Chief Financial Officer Charles River Laboratories International, Inc.

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Exhibit 32.1

CERTIFICATION PURSUANT TO 18 U.S.C. SECTION 1350,

AS ADOPTED PURSUANT TO

SECTION 906 OF THE SARBANES‑OXLEY ACT OF 2002

In connection with the quarterly report on Form 10-Q for the quarter ended March 31, 2012 of Charles River Laboratories International, Inc. (the “Company”) as filed with the Securities and Exchange Commission on the date hereof (the “Report”), the undersigned, James C. Foster, Chairman, Chief Executive Officer and President of the Company, and Thomas F. Ackerman, Corporate Executive Vice President and Chief Financial Officer of the Company, each hereby certifies, to the best of his knowledge and pursuant to 18 U.S.C. Section 1350, that:

(1) the Report fully complies with the requirements of Section 13(a) or 15(d) of the Securities Exchange Act of 1934 (the “Exchange Act”); and

(2) the information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Company.

Dated: May 4, 2012	/s/ James C. Foster James C. Foster Chairman, President and Chief Executive Officer Charles River Laboratories International, Inc.
Dated: May 4, 2012	/s/ Thomas F. Ackerman Thomas F. Ackerman Corporate Executive Vice President and Chief Financial Officer Charles River Laboratories International, Inc.

This certification shall not be deemed “filed” for any purpose, nor shall it be deemed to be incorporated by reference into any filing under the Securities Act of 1933 or the Exchange Act.

34

EX-31.1

Exhibit 31.1

CERTIFICATION PURSUANT TO

SECTION 302 OF THE SARBANES‑OXLEY ACT OF 2002

AND RULE 13a-14(a)/15d-14(a) OF THE EXCHANGE ACT OF 1934

I, James C. Foster, Chief Executive Officer of Charles River Laboratories International, Inc. (the Company) certify that:

1. I have reviewed this annual report on Form 10-Q for the quarter ended March 31, 2012 of the Company;

2. Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;

3. Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report;

4. The registrant's other certifying officer(s) and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the registrant and have:

a. designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our new supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this report is being prepared;

b. designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles;

c. evaluated the effectiveness of the registrant's disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures as of the end of the period covered by this report based on such evaluation; and

d. disclosed in this report any change in the registrant's internal control over financial reporting that occurred during the registrant's most recent fiscal quarter (the registrant's fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect, the registrant's internal control over financial reporting; and

5. The registrant's other certifying officer(s) and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the registrant's auditors and the audit committee of the registrant's board of directors (or persons performing the equivalent functions):

a. all significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the registrant's ability to record, process, summarize and report financial information; and

b. any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant's internal control over financial reporting.
 

Dated:	May 4, 2012	/s/ JAMES C. FOSTER
		James C. Foster Chairman, President and Chief Executive Officer Charles River Laboratories International, Inc.

EX-31.2

Exhibit 31.2

CERTIFICATION PURSUANT TO

SECTION 302 OF THE SARBANES‑OXLEY ACT OF 2002

AND RULE 13a-14(a)/15d-14(a) OF THE EXCHANGE ACT OF 1934

I, Thomas F. Ackerman, Corporate Executive Vice President and Chief Financial Officer of Charles River Laboratories International, Inc. (the Company) certify that:

1. I have reviewed this annual report on Form 10-Q for the quarter ended March 31, 2012 of the Company;

2. Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;

3. Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report;

4. The registrant's other certifying officer(s) and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the registrant and have:

a. designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this report is being prepared;

b. designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles;

c. evaluated the effectiveness of the registrant's disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures as of the end of the period covered by this report based on such evaluation; and

d. disclosed in this report any change in the registrant's internal control over financial reporting that occurred during the registrant's most recent fiscal quarter (the registrant's fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect, the registrant's internal control over financial reporting; and

5. The registrant's other certifying officer(s) and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the registrant's auditors and the audit committee of the registrant's board of directors (or persons performing the equivalent functions):

a. all significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the registrant's ability to record, process, summarize and report financial information; and

b. any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant's internal control over financial reporting.
 

Dated:	May 4, 2012	/s/ THOMAS F. ACKERMAN
		Thomas F. Ackerman Corporate Executive Vice President and Chief Financial Officer Charles River Laboratories International, Inc.

EX-32.1

Exhibit 32.1

CERTIFICATION PURSUANT TO 18 U.S.C. SECTION 1350,

AS ADOPTED PURSUANT TO

SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002

In connection with the quarterly report on Form 10-Q for the quarter ended March 31, 2012 of Charles River Laboratories International, Inc. (the “Company”) as filed with the Securities and Exchange Commission on the date hereof (the “Report”), the undersigned, James C. Foster, Chairman, Chief Executive Officer and President of the Company, and Thomas F. Ackerman, Corporate Executive Vice President and Chief Financial Officer of the Company, each hereby certifies, to the best of his knowledge and pursuant to 18 U.S.C. Section 1350, that:

(1) the Report fully complies with the requirements of Section 13(a) or 15(d) of the Securities Exchange Act of 1934 (the “Exchange Act”); and

(2) the information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Company.
 

Dated:	May 4, 2012	/s/ JAMES C. FOSTER
		Chairman, President and Chief Executive Officer Charles River Laboratories International, Inc.
Dated:	May 4, 2012	/s/ THOMAS F. ACKERMAN
		Corporate Executive Vice President and Chief Financial Officer Charles River Laboratories International, Inc.

This certification shall not be deemed "filed" for any purpose, nor shall it be deemed to be incorporated by reference into any filing under the Securities Act of 1933 or the Exchange Act.
 

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Marketable Securities and Equity-Method Affiliates (Equity-Method Affiliates) (Details) (USD $) In Thousands, unless otherwise specified	3 Months Ended
	Mar. 31, 2012	Dec. 26, 2009
Schedule of Equity Method Investments [Line Items]
Equity method affiliates, carrying value	$ 6,834
Biotechnology and Medical Device Companies [Member]
Schedule of Equity Method Investments [Line Items]
Limited partnership, committed contribution	6,147	20,000
Limited partnership, ownership (as a percentage)		12.00%
Income (loss) from limited partnership	$ 397

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Income Taxes (Details) (USD $) In Thousands, unless otherwise specified	3 Months Ended
	Mar. 31, 2012	Mar. 26, 2011
Income (loss) from continuing operations before income taxes
Income from continuing operations, before income taxes	$ 35,146	$ 32,662
Effective tax rate (as a percentage)	24.70%	(8.30%)
Provision (benefit) for income taxes	8,676	(2,715)
Benefit for income taxes due to disposition of business		11,111
Increase in unrecognized tax benefits	744
Unrecognized tax benefits	28,720
Increase in unrecognized tax benefits, that if recognized would impact the effective tax rate	459
Unrecognized tax benefits that would impact effective tax rate favorably, if recognized	22,936
Decrease in accrued interest related to unrecognized income tax benefits	(16)
Interest related to unrecognized income tax benefits	1,499
Income tax expense related to items of other comprehensive income	261	204
Income tax expense (beneffit) related to foreign currency translation adjustments	(89)	66
Income tax expense related to the change in unrecognized pension gains, losses and prior service costs	$ 350	$ 138

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Equity (Earnings Per Share) (Details) (USD $) In Thousands, except Share data, unless otherwise specified	3 Months Ended					3 Months Ended
	Mar. 31, 2012	Mar. 26, 2011	Mar. 31, 2012 2.25% Senior convertible debentures	Dec. 31, 2011 2.25% Senior convertible debentures	Mar. 26, 2011 2.25% Senior convertible debentures	Mar. 31, 2012 Stock options	Mar. 26, 2011 Stock options
Antidilutive securities excluded from computation of earnings per share amount
Antidilutive securities excluded from computation of earnings per share amount (in shares)						4,395,903	4,490,167
Numerator:
Income from continuing operations for purposes of calculating earnings per share	$ 26,362	$ 35,280
Income (loss) from discontinued operations	$ 77	$ (3,945)
Denominator:
Weighted average shares outstanding-Basic (in shares)	48,254,950	53,937,948
Effect of dilutive securities:
2.25% senior convertible debentures (in shares)	0	0
Stock options and contingently issued restricted stock (in shares)	516,793	659,792
Weighted average shares outstanding-Diluted (in shares)	48,771,743	54,597,740				930,193	761,173
Basic earnings per share from continuing operations attributable to common shareowners (in dollars per share)	$ 0.55	$ 0.65
Basic earnings (loss) per share from discontinued operations attributable to common shareowners (in dollars per share)	$ 0.00	$ (0.07)
Diluted earnings per share from continuing operations attributable to common shareowners (in dollars per share)	$ 0.54	$ 0.65
Diluted earnings (loss) per share from discontinued operations attributable to common shareowners (in dollars per share)	$ 0.00	$ (0.07)
Interest rate on debt (as a percent)			2.25%	2.25%	2.25%

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Business Segment Information (Tables)

3 Months Ended

Mar. 31, 2012

Segment Reporting [Abstract]

Schedule of Sales and Other Financial Information by Business Segment

The following table presents sales and other financial information by business segment.

	Three Months Ended
	March 31, 2012		March 26, 2011
Research Models and Services
Net sales	$	183,152	$	173,371
Gross margin	82,196		73,839
Operating income	59,467		51,742
Depreciation and amortization	8,942		9,269
Capital expenditures	12,900		4,403
Preclinical Services
Net sales	$	102,829	$	112,472
Gross margin	22,016		28,799
Operating income	4,174		9,306
Depreciation and amortization	11,060		11,996
Capital expenditures	1,211		2,387

Reconciliation of Segment Operating Income to Consolidated Operating Income

A reconciliation of segment operating income to consolidated operating income is as follows:

	Three Months Ended
	March 31, 2012			March 26, 2011
Total segment operating income	$	63,641		$	61,048
Unallocated corporate overhead	(19,901		)	(18,797		)
Consolidated operating income	$	43,740		$	42,251

Schedule of Net Sales for Each Significant Service Area

Net sales for each significant service area are as follows:

	Three Months Ended
	March 31, 2012		March 26, 2011
Research models	$	94,021	$	93,400
Research model services	56,331		51,975
Other products	32,800		27,996
Total research models	183,152		173,371
Total preclinical services	102,829		112,472
Total sales	$	285,981	$	285,843

Summary of Unallocated Corporate Overhead

A summary of unallocated corporate overhead consists of the following:

	Three Months Ended
	March 31, 2012		March 26, 2011
Stock-based compensation expense	$	2,785	$	2,986
U.S. retirement plans	1,372		1,057
Audit, tax and related expense	654		755
Salary and bonus	4,923		4,693
Global IT	2,850		2,993
Employee health, long-term disability and fringe benefit expense	1,993		1,639
Consulting and professional services	1,742		1,331
Depreciation expense	1,569		1,581
Other general unallocated corporate expenses	2,013		1,762
Total unallocated corporate overhead costs	$	19,901	$	18,797

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Marketable Securities and Equity-Method Affiliates (Tables)

3 Months Ended

Mar. 31, 2012

Marketable Securities and Equity-Method Affiliates [Abstract]

Schedule of Marketable Securities by Major Security Type

The amortized cost, gross unrealized gains, gross unrealized losses and fair value for marketable securities by major security type were as follows:

	March 31, 2012
	Amortized Cost		Gross Unrealized Gains		Gross Unrealized Losses		Fair Value
Time deposits	$	6,136	$	—	$	—	$	6,136
Auction rate securities	—		—		—		—
	$	6,136	$	—	$	—	$	6,136

	December 31, 2011
	Amortized Cost		Gross Unrealized Gains		Gross Unrealized Losses			Fair Value
Time deposits	$	5,359	$	—	$	—		$	5,359
Auction rate securities	11,972		—		(921		)	11,051
	$	17,331	$	—	$	(921	)	$	16,410

Schedule of Maturities of Debt Securities

Maturities of debt securities were as follows:

	March 31, 2012				December 31, 2011
	Amortized Cost		Fair Value		Amortized Cost		Fair Value
Due less than one year	$	6,136	$	6,136	$	5,359	$	5,359
Due after one year through five years	—		—		—		—
Due after ten years	—		—		11,972		11,051
	$	6,136	$	6,136	$	17,331	$	16,410

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Stock Plans and Stock Based Compensation (Stock Based Compensation Expense) (Details) (USD $) In Thousands, unless otherwise specified	3 Months Ended
	Mar. 31, 2012	Mar. 26, 2011
Stock-based compensation expense
Stock-based compensation expense	$ 5,266	$ 5,919
Provision for income taxes	(1,884)	(2,119)
Net income attributable to common shareowners	3,382	3,800
Cost of Sales [Member]
Stock-based compensation expense
Stock-based compensation expense	1,448	1,678
Selling and Administration [Member]
Stock-based compensation expense
Stock-based compensation expense	3,818	4,241
Performance Based Stock Award Program [Member]
Stock-based compensation expense
Stock-based compensation expense	$ (27)	$ 54

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Goodwill and Other Intangible Assets (Schedule of Goodwill and Other Intangible Assets) (Details) (USD $) In Thousands, unless otherwise specified	3 Months Ended															3 Months Ended	12 Months Ended
	Mar. 31, 2012	Mar. 26, 2011	Dec. 31, 2011	Mar. 31, 2012 Backlog [Member]	Dec. 31, 2011 Backlog [Member]	Mar. 31, 2012 Client Relationships [Member]	Dec. 31, 2011 Client Relationships [Member]	Mar. 31, 2012 Client Contracts [Member]	Dec. 31, 2011 Client Contracts [Member]	Mar. 31, 2012 Trademarks and Trade Names [Member]	Dec. 31, 2011 Trademarks and Trade Names [Member]	Mar. 31, 2012 Standard Operating Procedures [Member]	Dec. 31, 2011 Standard Operating Procedures [Member]	Mar. 31, 2012 Other Identifiable Intangible Assets [Member]	Dec. 31, 2011 Other Identifiable Intangible Assets [Member]	Mar. 31, 2012 Research Models [Member]	Dec. 31, 2011 Research Models [Member]
Goodwill and Intangible Assets Disclosure [Abstract]
Goodwill, Gross Carrying Amount	$ 1,215,639		$ 1,214,285
Goodwill, Accumulated Amortization & Impairment Loss	(1,016,757)		(1,016,724)
Other intangible assets
Other intangible assets not subject to amortization, Gross Carrying Amount																3,438	3,438
Amortization of Intangible assets	4,495	5,380														0	0
Other intangible assets subject to amortization, Gross Carrying Amount				2,885	2,856	304,125	298,813	15,232	14,818	5,028	5,022	652	650	5,464	5,415
Other intangible assets, Gross Carrying Amount	336,824		331,012
Other intangible assets subject to amortization, Accumulated Amortization & Impairment Loss	$ (246,370)		$ (237,575)	$ (2,293)	$ (2,253)	$ (219,045)	$ (210,816)	$ (15,232)	$ (14,818)	$ (4,738)	$ (4,706)	$ (652)	$ (650)	$ (4,410)	$ (4,332)

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Supplemental Balance Sheet Information (Long-lived Assets) (Details) (USD $) In Thousands, unless otherwise specified	3 Months Ended
	Mar. 31, 2012	Mar. 26, 2011	Dec. 31, 2011
Net property, plant and equipment
Gross property, plant and equipment	$ 1,299,820		$ 1,294,675
Less accumulated depreciation	(559,595)		(556,645)
Net property, plant and equipment	740,225		738,030
Depreciation expense	15,507	15,885
Land [Member]
Net property, plant and equipment
Gross property, plant and equipment	40,435		40,517
Buildings [Member]
Net property, plant and equipment
Gross property, plant and equipment	696,193		696,275
Machinery and Equipment [Member]
Net property, plant and equipment
Gross property, plant and equipment	351,761		348,795
Leashold Improvements [Member]
Net property, plant and equipment
Gross property, plant and equipment	27,987		29,975
Furniture and Fixtures [Member]
Net property, plant and equipment
Gross property, plant and equipment	12,214		10,663
Vehicles [Member]
Net property, plant and equipment
Gross property, plant and equipment	5,252		5,226
Computer Hardware and Software [Member]
Net property, plant and equipment
Gross property, plant and equipment	105,243		105,563
Construction in Progress [Member]
Net property, plant and equipment
Gross property, plant and equipment	$ 60,735		$ 57,661

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Business Segment Information (Details) (USD $) In Thousands, unless otherwise specified	3 Months Ended
	Mar. 31, 2012 segments	Mar. 26, 2011
Segment Reporting [Abstract]
Number of reportable segments	2
Business segment information
Net sales	$ 285,981	$ 285,843
Operating income	43,740	42,251
Depreciation and amortization	20,002	21,265
Capital expenditures	14,112	6,789
Unallocated corporate overhead
Stock-based compensation expense	5,266	5,919
Depreciation expense	15,507	15,885
Research Models [Member]
Business segment information
Net sales	94,021	93,400
Research Model Services [Member]
Business segment information
Net sales	56,331	51,975
Other Products [Member]
Business segment information
Net sales	32,800	27,996
Total Segments [Member]
Business segment information
Operating income	63,641	61,048
Research Models and Services [Member]
Business segment information
Net sales	183,152	173,371
Gross margin	82,196	73,839
Operating income	59,467	51,742
Depreciation and amortization	8,942	9,269
Capital expenditures	12,900	4,403
Preclinical Services [Member]
Business segment information
Net sales	102,829	112,472
Gross margin	22,016	28,799
Operating income	4,174	9,306
Depreciation and amortization	11,060	11,996
Capital expenditures	1,211	2,387
Unallocated Corporate Overhead [Member]
Business segment information
Operating income	(19,901)	(18,797)
Unallocated corporate overhead
Stock-based compensation expense	2,785	2,986
U.S. retirement plans	1,372	1,057
Audit, tax and related expenses	654	755
Salary and bonus	4,923	4,693
Global IT	2,850	2,993
Employee health, long-term disability and fringe benefit expense	1,993	1,639
Consulting and professional services	1,742	1,331
Depreciation expense	1,569	1,581
Other general unallocated corporate expenses	2,013	1,762
Total unallocated corporate overhead costs	$ 19,901	$ 18,797

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Equity (Treasury Stock) (Details) (USD $) In Thousands, except Share data, unless otherwise specified	3 Months Ended					1 Months Ended
	Mar. 31, 2012	Mar. 31, 2012 Open market repurchases	Mar. 26, 2011 Open market repurchases	Mar. 31, 2012 2000 Incentive Plan and 2007 Incentive Plan	Mar. 26, 2011 2000 Incentive Plan and 2007 Incentive Plan	Feb. 24, 2012 Accelerated stock repurchase programs
Treasury Shares and Accelerated Stock Repurchase Program (ASR)
Number of shares of common stock repurchased (in shares)	430,343	347,968	5,287,873	82,375	77,446	4,631,227
Total cost of repurchase of treasury shares	$ 15,480	$ 12,500	$ 192,834	$ 2,980	$ 2,848

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Restructuring and Contract Termination Costs

3 Months Ended

Mar. 31, 2012

Restructuring and Related Activities [Abstract]

Restructuring and Contract Termination Costs

Restructuring and Contract Termination Costs

We have implemented staffing reductions over the past few years to improve operating efficiency and profitability at various sites. As a result of these actions, for the three months ended March 31, 2012 and March 26, 2011, we recorded severance and retention charges as shown below. As of March 31, 2012, $1,892 was included in accrued compensation and $1,785 in other long-term liabilities on our consolidated balance sheet.

The following table rolls forward our severance and retention cost liability:

	Three Months Ended
	March 31, 2012			March 26, 2011
Balance, beginning of period	$	3,374		$	10,658
Expense	911			494
Payments/utilization	(608		)	(4,052		)
Balance, end of period	$	3,677		$	7,100

The following table presents severance and retention costs by classification on the income statement:

	Three Months Ended
	March 31, 2012		March 26, 2011
Severance charges included in cost of sales	$	—	$	241
Severance charges included in selling, general and administrative expense	911		253
Total expense	$	911	$	494

The following table presents severance and retention cost by segment:

	Three Months Ended
	March 31, 2012		March 26, 2011
Research models and services	$	—	$	229
Preclinical services	911		257
Corporate	—		8
Total expense	$	911	$	494

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Goodwill and Other Intangible Assets (Gross Carrying Amount and Accumulated Amortization of Goodwill) (Details) (USD $) In Thousands, unless otherwise specified	3 Months Ended
	Mar. 31, 2012
Changes in gross carrying amount and accumulated amortization of goodwill
Gross carrying amount, balance at the beginning of the period	$ 1,214,285
Accumulated impairment loss, balance at the beginning of the period	(1,005,000)
Accumulated amortization, balance at the beginning of the period	(11,724)
Gross carrying amount, foreign exchange/impairment	1,354
Accumulated impairment loss, foreign exchange/impairment	0
Accumulated amortization, foreign exchange/impairment	(33)
Gross carrying amount, balance at the end of the period	1,215,639
Accumulated impairment loss, balance at the end of the period	(1,005,000)
Accumulated amortization, balance at the end of the period	(11,757)
Research Models and Services [Member]
Changes in gross carrying amount and accumulated amortization of goodwill
Gross carrying amount, balance at the beginning of the period	56,402
Accumulated amortization, balance at the beginning of the period	(3,721)
Gross carrying amount, foreign exchange/impairment	309
Accumulated impairment loss, foreign exchange/impairment	0
Accumulated amortization, foreign exchange/impairment	(33)
Gross carrying amount, balance at the end of the period	56,711
Accumulated amortization, balance at the end of the period	(3,754)
Preclinical Services [Member]
Changes in gross carrying amount and accumulated amortization of goodwill
Gross carrying amount, balance at the beginning of the period	1,157,883
Accumulated impairment loss, balance at the beginning of the period	(1,005,000)
Accumulated amortization, balance at the beginning of the period	(8,003)
Gross carrying amount, foreign exchange/impairment	1,045
Accumulated impairment loss, foreign exchange/impairment	0
Accumulated amortization, foreign exchange/impairment	0
Gross carrying amount, balance at the end of the period	1,158,928
Accumulated impairment loss, balance at the end of the period	(1,005,000)
Accumulated amortization, balance at the end of the period	$ (8,003)

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Equity (Tables)

3 Months Ended

Mar. 31, 2012

Stockholders' Equity Note [Abstract]

Reconciliation of the Numerator and Denominator in the Computations of the Basic and Diluted Earnings Per Share

The following table illustrates the reconciliation of the numerator and denominator in the computations of the basic and diluted earnings per share:

	Three Months Ended
	March 31, 2012		March 26, 2011
Numerator:
Income from continuing operations for purposes of calculating earnings per share	$	26,362	$	35,280
Income (loss) from discontinued businesses	77		$	(3,945	)
Denominator:
Weighted-average shares outstanding—Basic	48,254,950		53,937,948
Effect of dilutive securities:
2.25% senior convertible debentures	—		—
Stock options and contingently issued restricted stock	516,793		659,792
Weighted-average shares outstanding—Diluted	48,771,743		54,597,740
Basic earnings per share from continuing operations attributable to common shareowners	$	0.55	$	0.65
Basic earnings (loss) per share from discontinued operations attributable to common shareowners	$	—	$	(0.07	)
Diluted earnings per share from continuing operations attributable to common shareowners	$	0.54	$	0.65
Diluted earnings (loss) per share from discontinued operations attributable to common shareowners	$	—	$	(0.07	)

Schedule of Number of Shares Repurchased and the Total Cost of Repurchase

Share repurchases for the three months ended March 31, 2012 and March 26, 2011 were as follows:

	Three Months Ended
	March 31, 2012		March 26, 2011
Number of shares of common stock repurchased	430,343		5,287,873
Total cost of repurchase	$	15,480	$	192,834

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Long-Term Debt and Capital Lease Obligations (Tables)

3 Months Ended

Mar. 31, 2012

Debt Disclosure [Abstract]

Components of Long-Term Debt

Long-term debt consists of the following:

	March 31, 2012			December 31, 2011
2.25% Senior convertible debentures:
Principal	$	349,995		$	349,995
Unamortized debt discount	(18,019		)	(21,533		)
Net carrying amount of senior convertible debentures	331,976			328,462
Term loan facilities	333,187			356,322
Revolving credit facility	39,000			33,000
Other long-term debt represents secured and unsecured promissory notes, interest rates ranging from 0% to 0.5% at both March 31, 2012 and December 31, 2011, maturing between 2012 and 2013	122			118
Total debt	704,285			717,902
Less: current portion of long-term debt	(29,549		)	(14,732		)
Long-term debt	$	674,736		$	703,170

Schedule of Principal Maturities of Existing Debt Excluding Unamortized Debt Discount

Principal maturities of existing debt, which excludes unamortized discount, for the periods set forth in the table below are as follows:

Twelve Months Ending
March 2013	$	29,549
March 2014	384,327
March 2015	63,759
March 2016	70,782
March 2017	173,887
Total	$	722,304

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Long-Term Debt and Capital Lease Obligations (Long-Term Debt) (Details) (USD $) In Thousands, unless otherwise specified										3 Months Ended	12 Months Ended
	Mar. 31, 2012	Dec. 31, 2011	Mar. 31, 2012 2.25% Senior convertible debentures	Dec. 31, 2011 2.25% Senior convertible debentures	Mar. 26, 2011 2.25% Senior convertible debentures	Mar. 31, 2012 Term loan facilities	Dec. 31, 2011 Term loan facilities	Mar. 31, 2012 Revolving credit facility	Dec. 31, 2011 Revolving credit facility	Mar. 31, 2012 Other long-term debt represents secured and unsecured promissory notes, interest rates ranging from 0% to 0.5%, 0% to 0.5% at both March 31, 2012 and December 31, 2011, respectively, maturing between 2012 and 2013	Dec. 31, 2011 Other long-term debt represents secured and unsecured promissory notes, interest rates ranging from 0% to 0.5%, 0% to 0.5% at both March 31, 2012 and December 31, 2011, respectively, maturing between 2012 and 2013
Debt Instrument
Principal	$ 722,304		$ 349,995	$ 349,995
Unamortized debt discount			(18,019)	(21,533)
Total debt	704,285	717,902	331,976	328,462		333,187	356,322	39,000	33,000	122	118
Less: current portion of long-term debt	(29,549)	(14,732)
Long-term debt	$ 674,736	$ 703,170
Interest rate on debt (as a percent)			2.25%	2.25%	2.25%
Interest rate on debt, minimum (as a percent)										0.00%	0.00%
Interest rate on debt, maximum (as a percent)										0.50%	0.50%

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Income Taxes (Tables)

3 Months Ended

Mar. 31, 2012

Income Tax Disclosure [Abstract]

Reconciliation of Provision for Income Taxes on Condensed Consolidated Statements of Operations

The following table provides a reconciliation of the provision for income taxes on the condensed consolidated statements of income:

	Three Months Ended
	March 31, 2012		March 26, 2011
Income from continuing operations before income taxes	35,146		32,662
Effective tax rate	24.7	%	(8.3	)%
Provision (benefit) for income taxes	8,676		(2,715	)

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Employee Benefits (Tables)

3 Months Ended

Mar. 31, 2012

Compensation and Retirement Disclosure [Abstract]

Components of Net Periodic Benefit Cost for Defined Benefit Plans

The following table provides thecomponents of net periodic benefit cost for our defined benefit plans:

	Pension Benefits						Supplemental Retirement Benefits
	March 31, 2012			March 26, 2011			March 31, 2012		March 26, 2011
Service cost	$	979		$	766		$	160	$	159
Interest cost	2,811			3,022			223		300
Expected return on plan assets	(3,430		)	(3,388		)	—		—
Amortization of prior service cost (credit)	(151		)	(154		)	165		125
Amortization of net loss (gain)	582			239			65		53
Net periodic benefit cost	791			485			613		637
Company contributions	$	5,685		$	3,591		$	—	$	—

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Basis of Presentation

3 Months Ended

Mar. 31, 2012

Organization, Consolidation and Presentation of Financial Statements [Abstract]

Basis of Presentation

Basis of Presentation

The condensed consolidated interim financial statements are unaudited, and certain information and footnote disclosures related thereto normally included in financial statements prepared in accordance with generally accepted accounting principles in the United States of America have been omitted in accordance with Rule 10-01 of Regulation S-X. In the opinion of management, the accompanying unaudited condensed consolidated financial statements were prepared following the same policies and procedures used in the preparation of the audited financial statements and reflect all adjustments (consisting of normal recurring adjustments) considered necessary to state fairly the financial position and results of operations of Charles River Laboratories International, Inc. The results of operations for the interim periods are not necessarily indicative of the results for the entire fiscal year. These condensed consolidated financial statements should be read in conjunction with our Annual Report on Form 10-K for the year ended December 31, 2011.

Certain amounts in prior-year financial statements and related notes have been reclassified to conform with the current year presentation.

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Stock Plans and Stock Based Compensation (Tables)

3 Months Ended

Mar. 31, 2012

Disclosure of Compensation Related Costs, Share-based Payments [Abstract]

Schedule of Stock-Based Compensation Expense

The following table presents stock-based compensation included in our consolidated statement of income:

	March 31, 2012			March 26, 2011
Stock-based compensation expense included in:
Cost of sales	$	1,448		$	1,678
Selling and administration	3,818			4,241
Stock-based compensation, before income taxes	5,266			5,919
Provision for income taxes	(1,884		)	(2,119		)
Stock-based compensation, net of tax	$	3,382		$	3,800

Schedule of Weighted-Average Assumptions

The fair value of stock-based awards granted during the first three months of 2012 and 2011 was estimated on the grant date using the Black-Scholes option-pricing model with the following weighted-average assumptions:

	March 31, 2012			March 26, 2011
Expected life (in years)	4.5			4.2
Expected volatility	35.0		%	33.5		%
Risk-free interest rate	0.84		%	2.23		%
Expected dividend yield	0		%	0		%
Weighted-average grant date fair value	$	11.02		$	11.29

Summary of Stock Option Activity in Equity Incentive Plans

The following table summarizes stock option activities under our plans:

	Shares		Weighted Average Exercise Price		Weighted Average Remaining Contractual Life (in years)	Aggregate Intrinsic Value
Options outstanding as of December 31, 2011	6,081,263		$	38.25
Options granted	543,065		$	36.25
Options exercised	(108,147	)	$	25.10
Options canceled	(84,662	)	$	39.85
Options outstanding as of March 31, 2012	6,431,519		$	38.28	3.71 years	$	14,757
Options exercisable as of March 31, 2012	4,374,304		$	39.78	2.83 years	$	10,842

Summary of Restricted Stock Activity

The following table summarizes the restricted stock activity for the three months ending March 31, 2012:

	Restricted Stock		Weighted Average Grant Date Fair Value
Outstanding as of December 31, 2011	703,011		$	35.70
Granted	499,360		36.25
Vested	(260,173	)	36.10
Canceled	(12,005	)	35.89
Outstanding as of March 31, 2012	930,193		$	35.61

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Fair Value (Summary of Assets and Liabilities Measured at Fair Value on Recurring Basis) (Details) (USD $) In Thousands, unless otherwise specified	3 Months Ended
	Mar. 31, 2012 Forward Contracts [Member]	Mar. 31, 2012 2.25% Senior convertible debentures [Member]	Dec. 31, 2011 2.25% Senior convertible debentures [Member]	Mar. 26, 2011 2.25% Senior convertible debentures [Member]	Mar. 31, 2012 Recurring Basis [Member]	Dec. 31, 2011 Recurring Basis [Member]	Mar. 31, 2012 Recurring Basis [Member] Quoted Prices in Active Markets for Identical Assets Level 1 [Member]	Dec. 31, 2011 Recurring Basis [Member] Quoted Prices in Active Markets for Identical Assets Level 1 [Member]	Mar. 31, 2012 Recurring Basis [Member] Significant Other Observable Inputs Level 2 [Member]	Dec. 31, 2011 Recurring Basis [Member] Significant Other Observable Inputs Level 2 [Member]	Mar. 31, 2012 Recurring Basis [Member] Significant Unobservable Inputs Level 3 [Member]	Dec. 31, 2011 Recurring Basis [Member] Significant Unobservable Inputs Level 3 [Member]	Mar. 31, 2012 Time Deposits [Member] Recurring Basis [Member]	Dec. 31, 2011 Time Deposits [Member] Recurring Basis [Member]	Mar. 31, 2012 Time Deposits [Member] Recurring Basis [Member] Quoted Prices in Active Markets for Identical Assets Level 1 [Member]	Dec. 31, 2011 Time Deposits [Member] Recurring Basis [Member] Quoted Prices in Active Markets for Identical Assets Level 1 [Member]	Mar. 31, 2012 Time Deposits [Member] Recurring Basis [Member] Significant Other Observable Inputs Level 2 [Member]	Dec. 31, 2011 Time Deposits [Member] Recurring Basis [Member] Significant Other Observable Inputs Level 2 [Member]	Mar. 31, 2012 Time Deposits [Member] Recurring Basis [Member] Significant Unobservable Inputs Level 3 [Member]	Dec. 31, 2011 Time Deposits [Member] Recurring Basis [Member] Significant Unobservable Inputs Level 3 [Member]	Mar. 31, 2012 Auction Rate Securities [Member] Recurring Basis [Member]	Dec. 31, 2011 Auction Rate Securities [Member] Recurring Basis [Member]	Mar. 31, 2012 Auction Rate Securities [Member] Recurring Basis [Member] Quoted Prices in Active Markets for Identical Assets Level 1 [Member]	Dec. 31, 2011 Auction Rate Securities [Member] Recurring Basis [Member] Quoted Prices in Active Markets for Identical Assets Level 1 [Member]	Mar. 31, 2012 Auction Rate Securities [Member] Recurring Basis [Member] Significant Other Observable Inputs Level 2 [Member]	Dec. 31, 2011 Auction Rate Securities [Member] Recurring Basis [Member] Significant Other Observable Inputs Level 2 [Member]	Mar. 31, 2012 Auction Rate Securities [Member] Recurring Basis [Member] Significant Unobservable Inputs Level 3 [Member]	Dec. 31, 2011 Auction Rate Securities [Member] Recurring Basis [Member] Significant Unobservable Inputs Level 3 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Fair value of life policies					$ 20,116	$ 19,520	$ 0	$ 0	$ 20,116	$ 19,520	$ 0	$ 0
Hedge contract					96	5	0	0	96	5	0	0
Total assets measured at fair value					26,348	35,935	0	0	26,348	24,884	0	11,051	6,136	5,359	0	0	6,136	5,359	0	0	0	11,051	0	0	0	0	0	11,051
Contingent consideration					0	0	0	0	0	0	0	0
Total liabilities measured at fair value					0	0	0	0	0	0	0	0
Interest rate on debt (as a percent)		2.25%	2.25%	2.25%
Fair value of debt		354,195
Hedge gains recorded	123
Outstanding forward contract, fair value	$ 96

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Discontinued Operations (Details) (USD $) In Thousands, unless otherwise specified	3 Months Ended
	Mar. 31, 2012	Mar. 26, 2011	Dec. 31, 2011	Jun. 25, 2011
Operating results from discontinued operations
Provision (benefit) for income taxes		$ (11,111)
Income (loss) from operations of discontinued businesses, net of taxes	77	(3,945)
Assets and liabilities of discontinued operations
Current assets	107		107
Long-term assets	959		986
Current liabilities	1,164		1,165
Long-term liabilities	2,452		2,522
Phase I Clinical Business [Member]
Operating results from discontinued operations
Facility lease payments	14,351
Net sales	0	2,112
Income (loss) from operatoins of discontinued businesses, before income taxes	104	(5,202)
Provision (benefit) for income taxes	27	(1,257)
Income (loss) from operations of discontinued businesses, net of taxes	77	(3,945)
Assets and liabilities of discontinued operations
Current assets	107		107
Long-term assets	959		986
Total assets	1,066		1,093
Current liabilities	1,164		1,165
Long-term liabilities	2,452		2,522	2,994
Total liabilities	$ 3,616		$ 3,687

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CONDENSED CONSOLIDATED STATEMENTS OF INCOME (USD $) In Thousands, except Per Share data, unless otherwise specified	3 Months Ended
	Mar. 31, 2012	Mar. 26, 2011
Net sales related to products	$ 126,214	$ 121,396
Net sales related to services	159,767	164,447
Net sales	285,981	285,843
Costs and expenses
Cost of products sold	64,945	65,766
Cost of services provided	116,824	117,439
Selling, general and administrative	55,977	55,007
Amortization of other intangibles	4,495	5,380
Operating income	43,740	42,251
Other income (expense)
Interest income	185	364
Interest expense	(8,435)	(10,016)
Other, net	(344)	63
Income from continuing operations, before income taxes	35,146	32,662
Provision (benefit) for income taxes	8,676	(2,715)
Income from continuing operations, net of income taxes	26,470	35,377
Income (loss) from discontinued operations, net of taxes	77	(3,945)
Net income	26,547	31,432
Less: Net income attributable to noncontrolling interests	(108)	(97)
Net income attributable to common shareowners	$ 26,439	$ 31,335
Basic:
Continuing operations attributable to common shareowners (in dollars per share)	$ 0.55	$ 0.65
Discontinued operations (in dollars per share)	$ 0.00	$ (0.07)
Net income attributable to common shareowners (in dollars per share)	$ 0.55	$ 0.58
Diluted:
Continuing operations attributable to common shareowners (in dollars per share)	$ 0.54	$ 0.65
Discontinued operations (in dollars per share)	$ 0.00	$ (0.07)
Net income attributable to common shareowners (in dollars per share)	$ 0.54	$ 0.57

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Long-Term Debt and Capital Lease Obligations (Additional Disclosures) (Details) In Thousands, unless otherwise specified			3 Months Ended				3 Months Ended
	Mar. 31, 2012 USD ($)	Dec. 31, 2011 USD ($)	Mar. 31, 2012 2.25% Senior convertible debentures USD ($) quarter	Mar. 26, 2011 2.25% Senior convertible debentures USD ($)	Dec. 31, 2011 2.25% Senior convertible debentures USD ($)	Mar. 31, 2012 Credit agreement USD ($)	Mar. 31, 2012 Term loan facilities payment	Mar. 31, 2012 Term loan USD ($)	Mar. 31, 2012 Euro term loan EUR (€)	Mar. 31, 2012 Revolving credit facility USD ($)
Debt Instrument [Line Items]
Maximum borrowing capacity								$ 299,750	€ 69,414	$ 350,000
Number of quarterly installment payments							20
Outstanding under letters of credit						4,325
Fair value			354,195
Unamortized debt discount			18,019		21,533
Amortization period of debt discount (in quarters)			5
Interest expense related to convertible debt			3,514	3,349
Effective interest rate (as a percent)			6.93%
Contractual interest expense recognized on convertible debt			1,969	1,969
Capital lease obligations	32	43
Principal maturities of existing debt excluding unamortized debt discount
March 2013	29,549
March 2014	384,327
March 2015	63,759
March 2016	70,782
March 2017	173,887
Total	$ 722,304		$ 349,995		$ 349,995

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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (USD $) In Thousands, unless otherwise specified	3 Months Ended
	Mar. 31, 2012	Mar. 26, 2011
Cash flows relating to operating activities
Net income	$ 26,547	$ 31,432
Less: Income (loss) from discontinued operations	77	(3,945)
Income from continuing operations	26,470	35,377
Adjustments to reconcile net income from continuing operations to net cash provided by operating activities:
Depreciation and amortization	20,002	21,265
Amortization of debt issuance costs and discounts	4,345	4,330
Non-cash compensation	5,266	5,919
Deferred income taxes	5,740	3,422
Other, net	1,535	518
Changes in assets and liabilities:
Trade receivables	(19,881)	(17,166)
Inventories	3,312	4,336
Other assets	(462)	(406)
Accounts payable	(2,187)	2,170
Accrued compensation	(1,659)	(4,188)
Deferred revenue	963	(8,073)
Accrued liabilities	(5,114)	187
Taxes payable and prepaid taxes	(7,320)	(23,365)
Other liabilities	(5,733)	(2,933)
Net cash provided by operating activities	25,277	21,393
Cash flows relating to investing activities
Capital expenditures	(14,112)	(6,789)
Purchases of investments	(4,694)	(9,548)
Proceeds from sale of investments	14,555	3,655
Other, net	973	146
Net cash used in investing activities	(3,278)	(12,536)
Cash flows relating to financing activities
Proceeds from long-term debt and revolving credit agreement	28,000	150,607
Proceeds from exercises of stock options and warrants	2,715	5,239
Payments on long-term debt, capital lease obligation and revolving credit agreement	(46,566)	(9,766)
Purchase of treasury stock and Accelerated Stock Repurchase Program	(15,246)	(174,465)
Other, net	462	(876)
Net cash used in financing activities	(30,635)	(29,261)
Discontinued operations
Net cash used in operating activities	0	(38)
Net cash provided by financing activities	0	213
Net cash provided by discontinued operations	0	175
Effect of exchange rate changes on cash and cash equivalents	762	(186)
Net change in cash and cash equivalents	(7,874)	(20,415)
Cash and cash equivalents, beginning of period	68,905	179,160
Cash and cash equivalents, end of period	61,031	158,745
Supplemental cash flow information
Capitalized interest	$ 191	$ 92

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Restructuring and Contract Termination Costs (Details) (USD $) In Thousands, unless otherwise specified	3 Months Ended
	Mar. 31, 2012	Mar. 26, 2011
Severance and Retention Costs
Balance, beginning of period	$ 3,374	$ 10,658
Expense	911	494
Payments/utilization	(608)	(4,052)
Balance, end of period	3,677	7,100
Severance and retention costs	911	494
Research Models and Services [Member]
Severance and Retention Costs
Severance and retention costs	0	229
Preclinical Services [Member]
Severance and Retention Costs
Severance and retention costs	911	257
Corporate [Member]
Severance and Retention Costs
Severance and retention costs	0	8
Cost of Sales [Member]
Severance and Retention Costs
Severance and retention costs	0	241
General and Administrative Expense [Member]
Severance and Retention Costs
Severance and retention costs	911	253
Accrued Compensation [Member]
Severance and Retention Costs
Severance and retention costs, current	1,892
Other Long-Term Liabilities [Member]
Severance and Retention Costs
Severance and retention costs, noncurrent	$ 1,785

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Fair Value (Policies)

3 Months Ended

Mar. 31, 2012

Fair Value Disclosures [Abstract]

Derivative Instruments

We enter into derivative instruments to hedge foreign currency exchange risk to reduce the impact of changes to foreign currency rates on our financial statements.

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Supplemental Balance Sheet Information (Details) (USD $) In Thousands, unless otherwise specified	Mar. 31, 2012	Dec. 31, 2011
Composition of trade receivables
Client receivables	$ 178,547	$ 159,381
Unbilled revenue	31,816	29,446
Total	210,363	188,827
Less allowance for doubtful accounts	(4,470)	(4,017)
Net trade receivables	205,893	184,810
Composition of inventories
Raw materials and supplies	13,808	13,987
Work in process	13,372	13,533
Finished products	62,167	65,449
Inventories	89,347	92,969
Composition of other current assets
Prepaid assets	22,269	22,828
Deferred tax asset	26,608	30,894
Marketable securities	6,136	5,359
Prepaid income tax	25,650	19,742
Restricted cash	229	229
Other current assets	80,892	79,052
Composition of other assets
Deferred financing costs	8,408	9,239
Cash surrender value of life insurance policies	25,706	25,057
Long-term marketable securities	0	11,051
Other assets	12,931	12,312
Other assets	47,045	57,659
Composition of other current liabilities
Accrued income taxes	8,983	10,552
Current deferred tax liability	1,415	1,379
Accrued intereset and other	4,063	2,102
Other current liabilities	14,461	14,033
Composition of other long-term liabilities
Deferred tax liability	13,602	16,074
Long-term pension liability	43,347	49,223
Accrued Executive Supplemental Life Insurance Retirement Plan and Deferred Compensation Plan	25,914	25,739
Other long-term liabilities	16,960	17,415
Other long-term liabilities	$ 99,823	$ 108,451

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Supplemental Balance Sheet Information (Tables)

3 Months Ended

Mar. 31, 2012

Supplemental Balance Sheet Information [Abstract]

Composition of Net Trade Receivables

The composition of net trade receivables is as follows:

	March 31, 2012			December 31, 2011
Client receivables	$	178,547		$	159,381
Unbilled revenue	31,816			29,446
Total	210,363			188,827
Less allowance for doubtful accounts	(4,470		)	(4,017		)
Net trade receivables	$	205,893		$	184,810

Composition of Inventories

The composition of inventories is as follows:

	March 31, 2012		December 31, 2011
Raw materials and supplies	$	13,808	$	13,987
Work in process	13,372		13,533
Finished products	62,167		65,449
Inventories	$	89,347	$	92,969

Composition of Other Current Assets

The composition of other current assets is as follows:

	March 31, 2012		December 31, 2011
Prepaid assets	$	22,269	$	22,828
Deferred tax asset	26,608		30,894
Marketable securities	6,136		5,359
Prepaid income tax	25,650		19,742
Restricted cash	229		229
Other current assets	$	80,892	$	79,052

Composition of Net Property, Plant and Equipment

The composition of net property, plant and equipment is as follows:

	March 31, 2012			December 31, 2011
Land	$	40,435		$	40,517
Buildings	696,193			696,275
Machinery and equipment	351,761			348,795
Leasehold improvements	27,987			29,975
Furniture and fixtures	12,214			10,663
Vehicles	5,252			5,226
Computer hardware and software	105,243			105,563
Construction in progress	60,735			57,661
Total	1,299,820			1,294,675
Less accumulated depreciation	(559,595		)	(556,645		)
Net property, plant and equipment	$	740,225		$	738,030

Composition of Other Assets

The composition of other assets is as follows:

	March 31, 2012		December 31, 2011
Deferred financing costs	$	8,408	$	9,239
Cash surrender value of life insurance policies	25,706		25,057
Long term marketable securities	—		11,051
Other assets	12,931		12,312
Other assets	$	47,045	$	57,659

Composition of Current Liabilities

The composition of other current liabilities is as follows:

	March 31, 2012		December 31, 2011
Accrued income taxes	$	8,983	$	10,552
Current deferred tax liability	1,415		1,379
Accrued interest and other	4,063		2,102
Other current liabilities	$	14,461	$	14,033

Composition of Other Long-Term Liabilities

The composition of other long-term liabilities is as follows:

	March 31, 2012		December 31, 2011
Deferred tax liability	$	13,602	$	16,074
Long-term pension liability	43,347		49,223
Accrued Executive Supplemental Life Insurance Retirement Plan and Deferred Compensation Plan	25,914		25,739
Other long-term liabilities	16,960		17,415
Other long-term liabilities	$	99,823	$	108,451

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CONDENSED CONSOLIDATED STATEMENTS OF CHANGES IN EQUITY (USD $) In Thousands, unless otherwise specified	Total	Accumulated (Deficit) Earnings	Accumulated Other Comprehensive Income	Common Stock	Capital in Excess of Par	Treasury Stock	Non-controlling Interest
Balance at Dec. 31, 2011	$ 527,363	$ (465,596)	$ 4,593	$ 785	$ 2,056,921	$ (1,071,120)	$ 1,780
Components of comprehensive income, net of tax:
Net income	26,547	26,439					108
Other comprehensive income	8,101		8,083				18
Total comprehensive income	34,648						126
Tax detriment associated with stock issued under employee compensation plans	(5)				(5)
Issuance of stock under employee compensation plans	2,713			5	2,708
Acquisition of treasury shares	(15,480)					(15,480)
Stock-based compensation	5,266				5,266
Balance at Mar. 31, 2012	$ 554,505	$ (439,157)	$ 12,676	$ 790	$ 2,064,890	$ (1,086,600)	$ 1,906

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CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE INCOME (USD $) In Thousands, unless otherwise specified	3 Months Ended
	Mar. 31, 2012	Mar. 26, 2011
Net income	$ 26,547	$ 31,432
Foreign currency translation adjustment	6,780	8,258
Unrealized gains (losses) on marketable securities:
Unrealized gains (losses) for the period	209	(85)
Less: reclassification adjustment for losses included in net income	712	0
Defined benefit plan gains (losses) and prior service costs not yet recognized as components of net periodic pension cost:
Prior service cost and gains (losses) for the period	0	0
Amortization of prior service costs and net gains and losses	661	263
Comprehensive income, before tax	34,909	39,868
Income tax expense related to items of other comprehensive income	261	204
Comprehensive income, net of tax	34,648	39,664
Less: comprehensive income related to noncontrolling interests	(126)	(109)
Comprehensive income attributable to common shareholders	$ 34,522	$ 39,555

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Employee Benefits

3 Months Ended

Mar. 31, 2012

Compensation and Retirement Disclosure [Abstract]

Employee Benefits

Employee Benefits

The following table provides thecomponents of net periodic benefit cost for our defined benefit plans:

	Pension Benefits						Supplemental Retirement Benefits
	March 31, 2012			March 26, 2011			March 31, 2012		March 26, 2011
Service cost	$	979		$	766		$	160	$	159
Interest cost	2,811			3,022			223		300
Expected return on plan assets	(3,430		)	(3,388		)	—		—
Amortization of prior service cost (credit)	(151		)	(154		)	165		125
Amortization of net loss (gain)	582			239			65		53
Net periodic benefit cost	791			485			613		637
Company contributions	$	5,685		$	3,591		$	—	$	—

During 2012, we expect to contribute $13,868 to our pension plans.

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Document and Entity Information	3 Months Ended
	Mar. 31, 2012	Apr. 20, 2012
Document and Entity Information [Abstract]
Entity Registrant Name	CHARLES RIVER LABORATORIES INTERNATIONAL INC
Entity Central Index Key	0001100682
Current Fiscal Year End Date	--12-29
Entity Filer Category	Large Accelerated Filer
Document Type	10-Q
Document Period End Date	Mar. 31, 2012
Document Fiscal Year Focus	2012
Document Fiscal Period Focus	Q1
Amendment Flag	false
Entity Common Stock, Shares Outstanding		48,995,692

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Stock Plans and Stock Based Compensation

3 Months Ended

Mar. 31, 2012

Disclosure of Compensation Related Costs, Share-based Payments [Abstract]

Stock Plans and Stock Based Compensation

Stock Plans and Stock Based Compensation

The estimated fair value of our stock-based awards, less expected forfeitures, is amortized over the awards' vesting period on a straight-line basis. The following table presents stock-based compensation included in our consolidated statement of income:

	March 31, 2012			March 26, 2011
Stock-based compensation expense included in:
Cost of sales	$	1,448		$	1,678
Selling and administration	3,818			4,241
Stock-based compensation, before income taxes	5,266			5,919
Provision for income taxes	(1,884		)	(2,119		)
Stock-based compensation, net of tax	$	3,382		$	3,800

The fair value of stock-based awards granted during the first three months of 2012 and 2011 was estimated on the grant date using the Black-Scholes option-pricing model with the following weighted-average assumptions:

	March 31, 2012			March 26, 2011
Expected life (in years)	4.5			4.2
Expected volatility	35.0		%	33.5		%
Risk-free interest rate	0.84		%	2.23		%
Expected dividend yield	0		%	0		%
Weighted-average grant date fair value	$	11.02		$	11.29

Stock Options

The following table summarizes stock option activities under our plans:

	Shares		Weighted Average Exercise Price		Weighted Average Remaining Contractual Life (in years)	Aggregate Intrinsic Value
Options outstanding as of December 31, 2011	6,081,263		$	38.25
Options granted	543,065		$	36.25
Options exercised	(108,147	)	$	25.10
Options canceled	(84,662	)	$	39.85
Options outstanding as of March 31, 2012	6,431,519		$	38.28	3.71 years	$	14,757
Options exercisable as of March 31, 2012	4,374,304		$	39.78	2.83 years	$	10,842

As of March 31, 2012, the unrecognized compensation cost related to 2,057,215 unvested stock options expected to vest was $18,792. This unrecognized compensation will be recognized over an estimated weighted-average amortization period of 32 months.

The total intrinsic value of options exercised during the three months ending March 31, 2012 and March 26, 2011 was $1,131 and $2,128, respectively, with intrinsic value defined as the difference between the market price on the date of exercise and the grant date price. The total amount of cash received from the exercise of options during the three months ending March 31, 2012 and March 26, 2011 was $2,715 and $5,239, respectively. The actual tax benefit realized for the tax deductions from option exercises totaled $374 for the three months ending March 31, 2012. A charge of $5 was recorded in capital in excess of par value in the first quarter for the excess of deferred tax assets over the actual tax benefits at option exercise. We settle stock option exercises with newly issued common shares.

Restricted Stock

Stock compensation expense associated with restricted common stock is charged for the market value on the date of grant, less estimated forfeitures, and is amortized over the awards' vesting period on a straight-line basis.

The following table summarizes the restricted stock activity for the three months ending March 31, 2012:

	Restricted Stock		Weighted Average Grant Date Fair Value
Outstanding as of December 31, 2011	703,011		$	35.70
Granted	499,360		36.25
Vested	(260,173	)	36.10
Canceled	(12,005	)	35.89
Outstanding as of March 31, 2012	930,193		$	35.61

As of March 31, 2012, the unrecognized compensation cost related to shares of unvested restricted stock expected to vest was $28,821. This unrecognized compensation will be recognized over an estimated weighted-average amortization period of 38 months. The total fair value of restricted stock grants that vested during the fiscal years ending March 31, 2012 and March 26, 2011 was $9,392 and $10,136, respectively. The actual tax benefit realized for the tax deductions from restricted stock grants that vested totaled $3,346 for the three months ended March 31, 2012.

Performance Based Stock Award Program

Compensation expense associated with performance-based stock awards of $(27) and $54 has been recorded during the three months ended March 31, 2012 and March 26, 2011, respectively.

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CONDENSED CONSOLIDATED BALANCE SHEETS (USD $) In Thousands, unless otherwise specified	Mar. 31, 2012	Dec. 31, 2011
Current assets
Cash and cash equivalents	$ 61,031	$ 68,905
Trade receivables, net	205,893	184,810
Inventories	89,347	92,969
Other current assets	80,892	79,052
Current assets of discontinued businesses	107	107
Total current assets	437,270	425,843
Property, plant and equipment, net	740,225	738,030
Goodwill, net	198,882	197,561
Other intangibles, net	90,454	93,437
Deferred tax asset	40,523	44,804
Other assets	47,045	57,659
Long-term assets of discontinued businesses	959	986
Total assets	1,555,358	1,558,320
Current liabilities
Current portion of long-term debt and capital leases	29,574	14,758
Accounts payable	32,353	34,332
Accrued compensation	40,199	41,602
Deferred revenue	58,195	56,530
Accrued liabilities	47,889	54,377
Other current liabilities	14,461	14,033
Current liabilities of discontinued businesses	1,164	1,165
Total current liabilities	223,835	216,797
Long-term debt and capital leases	674,743	703,187
Other long-term liabilities	99,823	108,451
Long-term liabilities of discontinued businesses	2,452	2,522
Total liabilities	1,000,853	1,030,957
Commitments and contingencies
Shareowners' equity
Preferred stock, $0.01 par value; 20,000,000 shares authorized; no shares issued and outstanding	0	0
Common stock, $0.01 par value; 120,000,000 shares authorized; 79,031,347 issued and 49,002,831 shares outstanding at March 31, 2012 and 78,473,888 issued and 48,875,715 shares outstanding at December 31, 2011	790	785
Capital in excess of par value	2,064,890	2,056,921
Accumulated deficit	(439,157)	(465,596)
Treasury stock, at cost, 30,028,516 shares and 29,598,173 shares at March 31, 2012 and December 31, 2011, respectively	(1,086,600)	(1,071,120)
Accumulated other comprehensive income	12,676	4,593
Total shareowners' equity	552,599	525,583
Noncontrolling interests	1,906	1,780
Total equity	554,505	527,363
Total liabilities and equity	$ 1,555,358	$ 1,558,320

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Fair Value

3 Months Ended

Mar. 31, 2012

Fair Value Disclosures [Abstract]

Fair Value

Fair Value

Valuation methodologies used for assets and liabilities measured or disclosed at fair value are as follows:

• Time deposits—Valued at their ending balances as reported by the financial institutions that hold our securities, which approximates fair value.

• Life policies—Valued at cash surrender value.

• Contingent consideration—Consists of future acquisition-related payments based on certain agreed upon revenue and technical milestones valued using the income approach.

• Hedge contract—Valued at fair value by management based on our foreign exchange rates and forward points provided by banks.

• Long-term debt—Valued based on current market pricing for similar debt.

Assets and liabilities measured at fair value on a recurring basis are summarized below:

	Fair Value Measurements at March 31, 2012 using
	Quoted Prices in Active Markets for Identical Assets Level 1		Significant Other Observable Inputs Level 2		Significant Unobservable Inputs Level 3		Assets and Liabilities at Fair Value
Time deposits	$	—	$	6,136	$	—	$	6,136
Auction rate securities	—		—		—		—
Fair value of life policies	—		20,116		—		20,116
Hedge contract	—		96		—		96
Total assets measured at fair value	$	—	$	26,348	$	—	$	26,348
Contingent consideration	—		—		—		—
Total liabilities measured at fair value	$	—	$	—	$	—	$	—

	Fair Value Measurements at December 31, 2011 using
	Quoted Prices in Active Markets for Identical Assets Level 1		Significant Other Observable Inputs Level 2		Significant Unobservable Inputs Level 3		Assets and Liabilities at Fair Value
Time deposits	$	—	$	5,359	$	—	$	5,359
Auction rate securities	—		—		11,051		11,051
Fair value of life policies	—		19,520		—		19,520
Hedge contract	—		5		—		5
Total assets measured at fair value	$	—	$	24,884	$	11,051	$	35,935
Contingent consideration	—		—		—		—
Total liabilities measured at fair value	$	—	$	—	$	—	$	—

The book value of our term and revolving loans, which are variable rate loans carried at amortized cost, approximates fair value based current market pricing of similar debt. The fair value of our 2.25% Senior Convertible Debentures (2013 Notes), which are carried at cost less unamortized discount on our consolidated balance sheets, was $354,195 as of March 31, 2012. We determine the fair value of these 2013 Notes based on their most recent quoted market price and by reference to the market value of similar debt instruments. We classify the fair value of our debt as Level 2 (significant other observable inputs) on the valuation hierarchy, where Level 2 inputs include quoted prices for similar assets and liabilities in active markets and/or quoted prices for identical or similar assets and liabilities in markets that are not active.

The following table presents a reconciliation for all assets measured at fair value on a recurring basis using significant unobservable inputs (Level 3) during the years ended March 31, 2012 and December 31, 2011. As of December 31, 2011, our auction rate securities were valued at fair value by management in part utilizing an independent valuation, which used pricing models and discounted cash flow methodologies incorporating assumptions that reflect the assumptions a marketplace participant would use.

	Fair Value Measurements Using Significant Unobservable Inputs (Level 3)
	Three Months Ended
Auction rate securities	March 31, 2012			March 26, 2011
Beginning balance	$	11,051		$	11,377
Transfers in and/or out of Level 3	—			—
Total gains or losses (realized/unrealized):
Included in other income (expense)	(712		)	(1		)
Included in other comprehensive income	921			(85		)
Purchases, issuances and settlements	(11,260		)	—
Ending balance	$	—		$	11,291

We enter into derivative instruments to hedge foreign currency exchange risk to reduce the impact of changes to foreign currency rates on our financial statements. During the quarter ended March 31, 2012, we recognized $123 of hedge gains associated with forward currency contracts open during the quarter. As of March 31, 2012, outstanding forward currency contracts had a fair value of $96.

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Marketable Securities and Equity-Method Affiliates

3 Months Ended

Mar. 31, 2012

Marketable Securities and Equity-Method Affiliates [Abstract]

Marketable Securities and Equity-Method Affiliates

Marketable Securities and Equity-Method Affiliates

Investments in marketable securities are reported at fair value and consist of time deposits and auction rate securities. During the period ended March 31, 2012, we sold our auction rate securities for $11,260 in cash and recorded a realized loss of $712, which is included in other income (expense).

The amortized cost, gross unrealized gains, gross unrealized losses and fair value for marketable securities by major security type were as follows:

	March 31, 2012
	Amortized Cost		Gross Unrealized Gains		Gross Unrealized Losses		Fair Value
Time deposits	$	6,136	$	—	$	—	$	6,136
Auction rate securities	—		—		—		—
	$	6,136	$	—	$	—	$	6,136

	December 31, 2011
	Amortized Cost		Gross Unrealized Gains		Gross Unrealized Losses			Fair Value
Time deposits	$	5,359	$	—	$	—		$	5,359
Auction rate securities	11,972		—		(921		)	11,051
	$	17,331	$	—	$	(921	)	$	16,410

Maturities of debt securities were as follows:

	March 31, 2012				December 31, 2011
	Amortized Cost		Fair Value		Amortized Cost		Fair Value
Due less than one year	$	6,136	$	6,136	$	5,359	$	5,359
Due after one year through five years	—		—		—		—
Due after ten years	—		—		11,972		11,051
	$	6,136	$	6,136	$	17,331	$	16,410

Equity-Method Affiliates

In 2009, we entered into a limited partnership, which invests in biotechnology and medical device companies. We committed $20,000, or approximately 12%, of the limited partnership's total committed capital. As of March 31, 2012, we have contributed $6,147 of our total committed capital of $20,000. We recognized equity income of $397 for the three months ended March 31, 2012. This income is reported as other income (expense). As of March 31, 2012, Equity Method Affiliates had a carrying value of $6,834, which is reported in other assets on the consolidated balance sheets.

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Restructuring and Contract Termination Costs (Tables)

3 Months Ended

Mar. 31, 2012

Restructuring and Related Activities [Abstract]

Schedule of Severance and Retention Costs

The following table rolls forward our severance and retention cost liability:

	Three Months Ended
	March 31, 2012			March 26, 2011
Balance, beginning of period	$	3,374		$	10,658
Expense	911			494
Payments/utilization	(608		)	(4,052		)
Balance, end of period	$	3,677		$	7,100

The following table presents severance and retention costs by classification on the income statement:

	Three Months Ended
	March 31, 2012		March 26, 2011
Severance charges included in cost of sales	$	—	$	241
Severance charges included in selling, general and administrative expense	911		253
Total expense	$	911	$	494

The following table presents severance and retention cost by segment:

	Three Months Ended
	March 31, 2012		March 26, 2011
Research models and services	$	—	$	229
Preclinical services	911		257
Corporate	—		8
Total expense	$	911	$	494

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Commitments and Contingencies

3 Months Ended

Mar. 31, 2012

Commitments and Contingencies Disclosure [Abstract]

Commitments and Contingencies

Commitments and Contingencies

Various lawsuits, claims and proceedings of a nature considered normal to our business are pending against us. In the opinion of management, the outcome of such proceedings and litigation currently pending will not materially affect our consolidated financial statements.

On January 31, 2012, a putative class action, entitled Irma Garcia v. Charles River Laboratories, Inc., was filed against us in the San Diego Superior Court, alleging various causes of action related to failure to make proper and timely payments to employees in California, failure to timely furnish accurate itemized wage statements, unfair business practices, associated penalties pursuant to California law, and declaratory relief. While no prediction may be made as to the outcome of litigation, we intend to defend against this proceeding vigorously and therefore an estimate of the possible loss or range of loss cannot be made.

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Equity

3 Months Ended

Mar. 31, 2012

Stockholders' Equity Note [Abstract]

Equity

Equity

Earnings Per Share

Basic earnings per share for the three months ended March 31, 2012 and March 26, 2011 was computed by dividing earnings available to common shareowners for these periods by the weighted average number of common shares outstanding in the respective periods adjusted for contingently issuable shares. The weighted average number of common shares outstanding for the three months ended March 31, 2012 and March 26, 2011 has been adjusted to include common stock equivalents for the purpose of calculating diluted earnings per share for these periods.

Options to purchase 4,395,903 shares and 4,490,167 shares were outstanding at March 31, 2012 and March 26, 2011, respectively, but were not included in computing diluted earnings per share because their inclusion would have been anti-dilutive. Basic weighted average shares outstanding for March 31, 2012 and March 26, 2011 excluded the weighted average impact of 930,193 and 761,173 shares, respectively, of non-vested fixed restricted stock awards.

The following table illustrates the reconciliation of the numerator and denominator in the computations of the basic and diluted earnings per share:

	Three Months Ended
	March 31, 2012		March 26, 2011
Numerator:
Income from continuing operations for purposes of calculating earnings per share	$	26,362	$	35,280
Income (loss) from discontinued businesses	77		$	(3,945	)
Denominator:
Weighted-average shares outstanding—Basic	48,254,950		53,937,948
Effect of dilutive securities:
2.25% senior convertible debentures	—		—
Stock options and contingently issued restricted stock	516,793		659,792
Weighted-average shares outstanding—Diluted	48,771,743		54,597,740
Basic earnings per share from continuing operations attributable to common shareowners	$	0.55	$	0.65
Basic earnings (loss) per share from discontinued operations attributable to common shareowners	$	—	$	(0.07	)
Diluted earnings per share from continuing operations attributable to common shareowners	$	0.54	$	0.65
Diluted earnings (loss) per share from discontinued operations attributable to common shareowners	$	—	$	(0.07	)

Treasury Shares

For the three months ended March 31, 2012 and March 26, 2011, we repurchased 347,968 shares of common stock for $12,500 and 579,200 shares of common stock for $21,607, respectively, through open market purchases made in reliance on Rule 10b5-1. Additionally, our 2000 Incentive Plan permits the netting of common stock upon vesting of restricted stock awards in order to satisfy individual tax withholding requirements. During the three months ended March 31, 2012 and March 26, 2011, we acquired 82,375 shares for $2,980 and 77,446 shares for $2,848, respectively, as a result of such withholdings. Additionally, the three months ended March 26, 2011 includes the acquisition of 4,631,227 shares under accelerated stock repurchase programs (ASR).

Share repurchases for the three months ended March 31, 2012 and March 26, 2011 were as follows:

	Three Months Ended
	March 31, 2012		March 26, 2011
Number of shares of common stock repurchased	430,343		5,287,873
Total cost of repurchase	$	15,480	$	192,834

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Goodwill and Other Intangible Assets

3 Months Ended

Mar. 31, 2012

Goodwill and Intangible Assets Disclosure [Abstract]

Goodwill and Other Intangible Assets

Goodwill and Other Intangible Assets

The following table displays goodwill and other intangible assets not subject to amortization and other intangible assets that continue to be subject to amortization:

	March 31, 2012					December 31, 2011
	Gross Carrying Amount		Accumulated Amortization & Impairment Loss			Gross Carrying Amount		Accumulated Amortization & Impairment Loss
Goodwill	$	1,215,639	$	(1,016,757	)	$	1,214,285	$	(1,016,724	)
Other intangible assets not subject to amortization:
Research models	$	3,438	$	—		$	3,438	$	—
Other intangible assets subject to amortization:
Backlog	2,885		(2,293		)	2,856		(2,253		)
Client relationships	304,125		(219,045		)	298,813		(210,816		)
Client contracts	15,232		(15,232		)	14,818		(14,818		)
Trademarks and trade names	5,028		(4,738		)	5,022		(4,706		)
Standard operating procedures	652		(652		)	650		(650		)
Other identifiable intangible assets	5,464		(4,410		)	5,415		(4,332		)
Total other intangible assets	$	336,824	$	(246,370	)	$	331,012	$	(237,575	)

The changes in the gross carrying amount and accumulated amortization of goodwill are as follows:

				Adjustments to Goodwill
	December 31, 2011			Acquisitions		Foreign Exchange/ Impairment			March 31, 2012
Research Models and Services
Gross carrying amount	$	56,402		$	—	$	309		$	56,711
Accumulated amortization	(3,721		)	—		(33		)	(3,754		)
Preclinical Services
Gross carrying amount	1,157,883			—		1,045			1,158,928
Accumulated impairment loss	(1,005,000		)	—		—			(1,005,000		)
Accumulated amortization	(8,003		)	—		—			(8,003		)
Total
Gross carrying amount	$	1,214,285		$	—	$	1,354		$	1,215,639
Accumulated impairment loss	(1,005,000		)	—		—			(1,005,000		)
Accumulated amortization	(11,724		)	—		(33		)	(11,757		)

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Long-Term Debt and Capital Lease Obligations

3 Months Ended

Mar. 31, 2012

Debt Disclosure [Abstract]

Long-Term Debt and Capital Lease Obligations

Long-Term Debt and Capital Lease Obligations

Long-Term Debt

Long-term debt consists of the following:

	March 31, 2012			December 31, 2011
2.25% Senior convertible debentures:
Principal	$	349,995		$	349,995
Unamortized debt discount	(18,019		)	(21,533		)
Net carrying amount of senior convertible debentures	331,976			328,462
Term loan facilities	333,187			356,322
Revolving credit facility	39,000			33,000
Other long-term debt represents secured and unsecured promissory notes, interest rates ranging from 0% to 0.5% at both March 31, 2012 and December 31, 2011, maturing between 2012 and 2013	122			118
Total debt	704,285			717,902
Less: current portion of long-term debt	(29,549		)	(14,732		)
Long-term debt	$	674,736		$	703,170

Our credit agreement dated September 23, 2011 provides for a $299,750 term loan, a €69,414 Euro term loan and a $350,000 revolving credit facility. The term loan facility matures in 20 quarterly installments with the last installment due September 23, 2016. The $350,000 revolving facility also matures on September 23, 2016 and requires no scheduled payment before that date. The book value of our term and revolving loans approximates fair value.

The credit agreement includes certain customary representations and warranties, events of default, notices of material adverse changes to our business and negative and affirmative covenants. As of March 31, 2012, we were compliant with all financial covenants specified in the credit agreement. We had $4,325 outstanding under letters of credit as of March 31, 2012.

As of March 31, 2012, our debt included $349,995 of 2.25% Senior Convertible Debentures (2013 Notes) due June 2013. At March 31, 2012, the fair value of these outstanding 2013 Notes was approximately $354,195 based on their quoted market value and no conversion triggers were met.

As of March 31, 2012, $18,019 of debt discount related to the 2013 Notes remained and will be amortized over 5 quarters. Interest expense related to our convertible debt of $3,514 and $3,349 for quarters ending March 31, 2012 and March 26, 2011 respectively, yielded an effective interest rate of 6.93% on the liability component. In addition, $1,969 and $1,969 of contractual interest expense was recognized on our convertible debt during the years ended March 31, 2012 and March 26, 2011, respectively.

Principal maturities of existing debt, which excludes unamortized discount, for the periods set forth in the table below are as follows:

Twelve Months Ending
March 2013	$	29,549
March 2014	384,327
March 2015	63,759
March 2016	70,782
March 2017	173,887
Total	$	722,304

We have capital leases for equipment. These leases are capitalized using interest rates considered appropriate at the inception of the lease. Capital lease obligations amounted to $32 and $43 at March 31, 2012 and December 31, 2011, respectively.

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Income Taxes

3 Months Ended

Mar. 31, 2012

Income Tax Disclosure [Abstract]

Income Taxes

Income Taxes

The following table provides a reconciliation of the provision for income taxes on the condensed consolidated statements of income:

	Three Months Ended
	March 31, 2012		March 26, 2011
Income from continuing operations before income taxes	35,146		32,662
Effective tax rate	24.7	%	(8.3	)%
Provision (benefit) for income taxes	8,676		(2,715	)

Our overall effective tax rate was 24.7% in the first quarter of 2012 and (8.3)% in the first quarter of 2011. The change was primarily attributable to an $11,111 tax benefit recorded in the first quarter of 2011 associated with a tax loss incurred with the disposition of our Phase I clinical business. Additionally, there was an increase in tax rate in the first quarter of 2012 compared to the first quarter of 2011 primarily due to an unbenefitted capital loss on the sale of auction rate securities incurred during the first quarter of 2012 and lower research and development tax benefits. These increases were partially offset by reductions in the tax rate in the first quarter of 2012 compared to the first quarter of 2011 due to increased benefits from the domestic production deduction and a reduction in unbenefitted losses primarily driven by the disposition of our preclinical services operations in Shanghai.

In accordance with Canadian Federal tax law, we claim scientific research and experimental development (SR&ED) credits on qualified research and development costs incurred by our preclinical services facility in Canada in the performance of projects for non-Canadian clients. Additionally, in accordance with the tax law of the United Kingdom, we claim enhanced deductions related to qualified research and development costs incurred by our preclinical services facility in Edinburgh, Scotland, in the performance of certain client contracts.

During the fourth quarter of 2010, we took actions to divest of our Phase 1 clinical business. We recorded in discontinued operations a deferred tax asset associated with the excess of the tax outside basis over the basis for financial reporting purposes of the Phase 1 clinical business. As of the fourth quarter of 2010, we determined that we did not meet the more-likely-than-not realization threshold for this deferred tax asset and we recorded a valuation allowance against it as part of discontinued operations. During the first quarter of 2011, we determined that the tax loss would more-likely-than-not be benefitted as a worthless stock deduction. As such, we released the valuation allowance recorded against the tax loss on the Phase 1 clinical business and recognized the benefit in continuing operations.

During the first quarter of 2012, our unrecognized tax benefits recorded increased by $744 to $28,720 primarily due to ongoing evaluation of uncertain tax positions in the current period and foreign exchange movement offset by the settlement of a U.S. state audit. The amount of unrecognized income tax benefits that would impact the effective tax rate favorably increased by $459 to $22,936, and the amount of accrued interest on unrecognized tax benefits decreased by $16 to $1,499 in the first quarter of 2012.

We conduct business in a number of tax jurisdictions. As a result, we are subject to tax audits in jurisdictions including, but not limited to, the United States, the United Kingdom, Japan, France, Germany and Canada. With few exceptions, we are no longer subject to U.S. and international income tax examinations for years before 2005.

We and certain of our subsidiaries are currently under audit by the Canadian Revenue Authority (CRA), the Minister of Revenue Quebec provincial tax authority (MRQ) and various state tax authorities. We do not believe that resolution of these controversies will have a material impact on our financial position or results of operations.

We are challenging the reassessments received by the CRA with respect to the SR&ED credits claimed in 2003 and 2004 by our Canadian Preclinical Services subsidiary in the Tax Court of Canada (TCC). Additionally, we filed Notices of Objection in response to Notices of Reassessment received from the MRQ with respect to our 2003 and 2004 claims for the Quebec Research and Development tax credits. We disagree with the positions taken by the CRA and MRQ with regard to the credits claimed. We believe that it is reasonably possible that we will conclude the controversies with the TCC and MRQ within the next twelve months. We do not believe that resolution of these controversies will have a material impact on our financial position or results of operations. However, it is possible that the CRA and MRQ will propose similar adjustments for later years.

We believe we have appropriately provided for all uncertain tax positions.

In accordance with our policy, the undistributed earnings of our non-U.S. subsidiaries remain indefinitely reinvested as of the end of the first quarter of 2012 as they are required to fund needs outside the U.S. and cannot be repatriated in a manner that is substantially tax free.

For the three months ended March 31, 2012, income tax expense of $261 related to items of other comprehensive income included a $89 benefit related to foreign currency translation adjustments and $350 of tax expenses related to the change in unrecognized pension gains, losses and prior service costs. For the three months ended March 26, 2011, income tax expense of $204 related to items of other comprehensive income included $66 related to foreign currency translation adjustments and $138 related to the change in unrecognized pension gains, losses and prior service costs.

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Discontinued Operations (Tables)

3 Months Ended

Mar. 31, 2012

Discontinued Operations and Disposal Groups [Abstract]

Schedule of Operating Results from Discontinued Operations

Operating results from discontinued operations are as follows:

	Three Months Ended
	March 31, 2012		March 26, 2011
Net sales	$	—	$	2,112
Income (loss) from operations of discontinued businesses, before income taxes	104		(5,202		)
Provision (benefit) for income taxes	27		(1,257		)
Income (loss) from operations of discontinued businesses, net of taxes	$	77	$	(3,945	)

Schedule of Assets and Liabilities of Discontinued Operations

Assets and liabilities of discontinued operations at March 31, 2012 and December 31, 2011 consisted of the following:

	March 31, 2012		December 31, 2011
Current assets	$	107	$	107
Long-term assets	959		986
Total assets	$	1,066	$	1,093
Current liabilities	$	1,164	$	1,165
Long-term liabilities	2,452		2,522
Total liabilities	$	3,616	$	3,687

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Stock Plans and Stock Based Compensation (Stock Options and Restricted Stock Grants) (Details) (USD $) In Thousands, except Share data, unless otherwise specified	3 Months Ended
	Mar. 31, 2012 year	Mar. 26, 2011 year
Stock-based compensation weighted-average assumptions
Expected life (in years)	4.5	4.2
Expected volatility (as a percent)	35.00%	33.50%
Risk-free interest rate (as a percent)	0.84%	2.23%
Expected dividend yield (as a percent)	0.00%	0.00%
Weighted-average grant date fair value (in dollars per share)	$ 11.02	$ 11.29
Stock option activity, additional disclosures
Charge recorded in capital in excess of par value for excess of deferred tax assets over actual tax benefits	$ 5
Stock options [Member]
Stock option activity, shares
Options outstanding, balance at the beginning of the period (in shares)	6,081,263
Options granted (in shares)	543,065
Options exercised (in shares)	(108,147)
Options canceled (in shares)	(84,662)
Options outstanding, balance at the end of the period (in shares)	6,431,519
Options exercisable, balance at the end of the period (in shares)	4,374,304
Stock option activity, weighted-average exercise price
Options outstanding, balance at the beginning of the period (in dollars per share)	$ 38.25
Options granted (in dollars per share)	$ 36.25
Options exercised (in dollars per share)	$ 25.10
Options canceled (in dollars per share)	$ 39.85
Options outstanding, balance at the end of the period (in dollars per share)	$ 38.28
Options exercisable, balance at the end of the period (in dollars per share)	$ 39.78
Stock option activity, weighted-average remaining contractual life
Options outstanding, balance at the end of the period (in years)	3.71
Options exercisable, balance at the end of the period (in years)	2.83
Stock option activity, Aggregate Intrinsic Value
Options outstanding, balance at the end of the period	14,757
Options exercisable, balance at the end of the period	10,842
Unrecognized compensation expense
Number of unvested awards related to unrecognized compensation cost (in shares)	2,057,215
Unrecognized compensation cost	18,792
Estimated weighted-average amortization period for unrecognized compensation cost (in months)	32
Stock option activity, additional disclosures
Intrinsic value of options exercised	1,131	2,128
Amount of cash received from exercise of options	2,715	5,239
Actual tax benefit realized for tax deductions from option exercises	374
Restricted Stock [Member]
Unrecognized compensation expense
Unrecognized compensation cost	28,821
Estimated weighted-average amortization period for unrecognized compensation cost (in months)	38
Restricted stock activity, restricted stock
Balance at the beginning of the period (in shares)	703,011
Granted (in shares)	499,360
Vested (in shares)	(260,173)
Canceled (in shares)	(12,005)
Balance at the end of the period (in shares)	930,193
Restricted stock activity, weighted-average grant date fair value
Balance at the beginning of the period (in dollars per share)	$ 35.70
Granted (in dollars per share)	$ 36.25
Vested (in dollars per share)	$ 36.10
Canceled (in dollars per share)	$ 35.89
Balance at the end of the period (in dollars per share)	$ 35.61
Restricted stock activity, additional disclosures
Fair value of restricted stock grants that vested	9,392	10,136
Actual tax benefit realized from vested restricted stock grants	$ 3,346

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Discontinued Operations

3 Months Ended

Mar. 31, 2012

Discontinued Operations and Disposal Groups [Abstract]

Discontinued Operations

Discontinued Operations

On March 28, 2011, we disposed of our Phase I clinical business for a nominal amount. As part of the disposition we remained the guarantor of the Phase I facility lease. During the second quarter of 2011, we recognized the value of the guarantee net of the buyer's related indemnity as a liability of $2,994, which we are accreting ratably over the remaining term of the lease. The facility lease runs through January 2021 with remaining lease payments totaling $14,351 as of March 31, 2012.

The consolidated financial statements have been reclassified to segregate, as discontinued operations, the assets and liabilities, operating results and cash flows, of the businesses being discontinued for all periods presented. Operating results from discontinued operations are as follows:

	Three Months Ended
	March 31, 2012		March 26, 2011
Net sales	$	—	$	2,112
Income (loss) from operations of discontinued businesses, before income taxes	104		(5,202		)
Provision (benefit) for income taxes	27		(1,257		)
Income (loss) from operations of discontinued businesses, net of taxes	$	77	$	(3,945	)

Assets and liabilities of discontinued operations at March 31, 2012 and December 31, 2011 consisted of the following:

	March 31, 2012		December 31, 2011
Current assets	$	107	$	107
Long-term assets	959		986
Total assets	$	1,066	$	1,093
Current liabilities	$	1,164	$	1,165
Long-term liabilities	2,452		2,522
Total liabilities	$	3,616	$	3,687

Current assets and non-current assets include a short-term and long-term deferred tax asset related to lease guarantee. Current and long-term liabilities consist of the carrying value of the lease guarantee and accrued expenses.

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Fair Value (Tables)

3 Months Ended

Mar. 31, 2012

Fair Value Disclosures [Abstract]

Summary of Assets and Liabilities Measured at Fair Value on a Recurring Basis

Assets and liabilities measured at fair value on a recurring basis are summarized below:

	Fair Value Measurements at March 31, 2012 using
	Quoted Prices in Active Markets for Identical Assets Level 1		Significant Other Observable Inputs Level 2		Significant Unobservable Inputs Level 3		Assets and Liabilities at Fair Value
Time deposits	$	—	$	6,136	$	—	$	6,136
Auction rate securities	—		—		—		—
Fair value of life policies	—		20,116		—		20,116
Hedge contract	—		96		—		96
Total assets measured at fair value	$	—	$	26,348	$	—	$	26,348
Contingent consideration	—		—		—		—
Total liabilities measured at fair value	$	—	$	—	$	—	$	—

	Fair Value Measurements at December 31, 2011 using
	Quoted Prices in Active Markets for Identical Assets Level 1		Significant Other Observable Inputs Level 2		Significant Unobservable Inputs Level 3		Assets and Liabilities at Fair Value
Time deposits	$	—	$	5,359	$	—	$	5,359
Auction rate securities	—		—		11,051		11,051
Fair value of life policies	—		19,520		—		19,520
Hedge contract	—		5		—		5
Total assets measured at fair value	$	—	$	24,884	$	11,051	$	35,935
Contingent consideration	—		—		—		—
Total liabilities measured at fair value	$	—	$	—	$	—	$	—

Reconciliation of all Assets and Liabilities Measured at Fair Value on a Recurring Basis Using Significant Unobservable Inputs (Level 3)

The following table presents a reconciliation for all assets measured at fair value on a recurring basis using significant unobservable inputs (Level 3) during the years ended March 31, 2012 and December 31, 2011. As of December 31, 2011, our auction rate securities were valued at fair value by management in part utilizing an independent valuation, which used pricing models and discounted cash flow methodologies incorporating assumptions that reflect the assumptions a marketplace participant would use.

	Fair Value Measurements Using Significant Unobservable Inputs (Level 3)
	Three Months Ended
Auction rate securities	March 31, 2012			March 26, 2011
Beginning balance	$	11,051		$	11,377
Transfers in and/or out of Level 3	—			—
Total gains or losses (realized/unrealized):
Included in other income (expense)	(712		)	(1		)
Included in other comprehensive income	921			(85		)
Purchases, issuances and settlements	(11,260		)	—
Ending balance	$	—		$	11,291

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Employee Benefits (Details) (USD $) In Thousands, unless otherwise specified	3 Months Ended
	Mar. 31, 2012	Mar. 26, 2011
Pension Benefits [Member]
Employee benefits
Service cost	$ 979	$ 766
Interest cost	2,811	3,022
Expected return on plan assets	(3,430)	(3,388)
Amortization of prior service cost (credit)	(151)	(154)
Amortization of net loss (gain)	582	239
Net periodic benefit cost	791	485
Company contributions	5,685	3,591
Expected contributions during the current fiscal year	13,868
Supplemental Retirement Benefits [Member]
Employee benefits
Service cost	160	159
Interest cost	223	300
Expected return on plan assets	0	0
Amortization of prior service cost (credit)	165	125
Amortization of net loss (gain)	65	53
Net periodic benefit cost	613	637
Company contributions	$ 0	$ 0

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Fair Value (Reconciliation of Assets on a Recurring Bais Using Significant Unobservable Inputs) (Details) (Auction Rate Securities [Member], USD $) In Thousands, unless otherwise specified	3 Months Ended
	Mar. 31, 2012	Mar. 26, 2011
Auction Rate Securities [Member]
Reconciliation of all assets measured at fair value on a recurring basis using significant unobservable inputs (Level 3)
Balance at the beginning of the period	$ 11,051	$ 11,377
Transfers in and/or out of Level 3	0	0
Total gains or losses (realized/unrealized): Included in other income (expenses)	(712)	(1)
Total gains or losses (realized/unrealized): Included in other comprehensive income	921	(85)
Purchases, issuances and settlements	(11,260)	0
Balance at the end of the period	$ 0	$ 11,291

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CONDENSED CONSOLIDATED BALANCE SHEETS (Parenthetical) (USD $)	Mar. 31, 2012	Dec. 31, 2011
Statement of Financial Position [Abstract]
Preferred stock, par value (in dollars per share)	$ 0.01	$ 0.01
Preferred stock, shares authorized	20,000,000	20,000,000
Preferred stock, shares issued	0	0
Preferred stock, shares outstanding	0	0
Common stock, par value (in dollars per share)	$ 0.01	$ 0.01
Common stock, shares authorized	120,000,000	120,000,000
Common stock, shares issued	79,031,347	78,473,888
Common stock, shares outstanding	49,002,831	48,875,715
Treasury stock, shares	30,028,516	29,598,173

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Supplemental Balance Sheet Information

3 Months Ended

Mar. 31, 2012

Supplemental Balance Sheet Information [Abstract]

Supplemental Balance Sheet Information

Supplemental Balance Sheet Information

The composition of net trade receivables is as follows:

	March 31, 2012			December 31, 2011
Client receivables	$	178,547		$	159,381
Unbilled revenue	31,816			29,446
Total	210,363			188,827
Less allowance for doubtful accounts	(4,470		)	(4,017		)
Net trade receivables	$	205,893		$	184,810

The composition of inventories is as follows:

	March 31, 2012		December 31, 2011
Raw materials and supplies	$	13,808	$	13,987
Work in process	13,372		13,533
Finished products	62,167		65,449
Inventories	$	89,347	$	92,969

The composition of other current assets is as follows:

	March 31, 2012		December 31, 2011
Prepaid assets	$	22,269	$	22,828
Deferred tax asset	26,608		30,894
Marketable securities	6,136		5,359
Prepaid income tax	25,650		19,742
Restricted cash	229		229
Other current assets	$	80,892	$	79,052

The composition of net property, plant and equipment is as follows:

	March 31, 2012			December 31, 2011
Land	$	40,435		$	40,517
Buildings	696,193			696,275
Machinery and equipment	351,761			348,795
Leasehold improvements	27,987			29,975
Furniture and fixtures	12,214			10,663
Vehicles	5,252			5,226
Computer hardware and software	105,243			105,563
Construction in progress	60,735			57,661
Total	1,299,820			1,294,675
Less accumulated depreciation	(559,595		)	(556,645		)
Net property, plant and equipment	$	740,225		$	738,030

Depreciation is calculated for financial reporting purposes using the straight-line method based on the estimated useful lives of the assets. Depreciation expense for the quarter ended March 31, 2012 and March 26, 2011 was $15,507 and $15,885, respectively.

The composition of other assets is as follows:

	March 31, 2012		December 31, 2011
Deferred financing costs	$	8,408	$	9,239
Cash surrender value of life insurance policies	25,706		25,057
Long term marketable securities	—		11,051
Other assets	12,931		12,312
Other assets	$	47,045	$	57,659

The composition of other current liabilities is as follows:

	March 31, 2012		December 31, 2011
Accrued income taxes	$	8,983	$	10,552
Current deferred tax liability	1,415		1,379
Accrued interest and other	4,063		2,102
Other current liabilities	$	14,461	$	14,033

The composition of other long-term liabilities is as follows:

	March 31, 2012		December 31, 2011
Deferred tax liability	$	13,602	$	16,074
Long-term pension liability	43,347		49,223
Accrued Executive Supplemental Life Insurance Retirement Plan and Deferred Compensation Plan	25,914		25,739
Other long-term liabilities	16,960		17,415
Other long-term liabilities	$	99,823	$	108,451

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Goodwill and Other Intangible Assets (Tables)

3 Months Ended

Mar. 31, 2012

Goodwill and Intangible Assets Disclosure [Abstract]

Schedule of Goodwill and Other Intangible Assets not Subject to Amortization and Other Intangible Assets that Continue to be Subject to Amortization

The following table displays goodwill and other intangible assets not subject to amortization and other intangible assets that continue to be subject to amortization:

	March 31, 2012					December 31, 2011
	Gross Carrying Amount		Accumulated Amortization & Impairment Loss			Gross Carrying Amount		Accumulated Amortization & Impairment Loss
Goodwill	$	1,215,639	$	(1,016,757	)	$	1,214,285	$	(1,016,724	)
Other intangible assets not subject to amortization:
Research models	$	3,438	$	—		$	3,438	$	—
Other intangible assets subject to amortization:
Backlog	2,885		(2,293		)	2,856		(2,253		)
Client relationships	304,125		(219,045		)	298,813		(210,816		)
Client contracts	15,232		(15,232		)	14,818		(14,818		)
Trademarks and trade names	5,028		(4,738		)	5,022		(4,706		)
Standard operating procedures	652		(652		)	650		(650		)
Other identifiable intangible assets	5,464		(4,410		)	5,415		(4,332		)
Total other intangible assets	$	336,824	$	(246,370	)	$	331,012	$	(237,575	)

Schedule of Changes in the Gross Carrying Amount and Accumulated Amortization of Goodwill

The changes in the gross carrying amount and accumulated amortization of goodwill are as follows:

				Adjustments to Goodwill
	December 31, 2011			Acquisitions		Foreign Exchange/ Impairment			March 31, 2012
Research Models and Services
Gross carrying amount	$	56,402		$	—	$	309		$	56,711
Accumulated amortization	(3,721		)	—		(33		)	(3,754		)
Preclinical Services
Gross carrying amount	1,157,883			—		1,045			1,158,928
Accumulated impairment loss	(1,005,000		)	—		—			(1,005,000		)
Accumulated amortization	(8,003		)	—		—			(8,003		)
Total
Gross carrying amount	$	1,214,285		$	—	$	1,354		$	1,215,639
Accumulated impairment loss	(1,005,000		)	—		—			(1,005,000		)
Accumulated amortization	(11,724		)	—		(33		)	(11,757		)

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Marketable Securities and Equity-Method Affiliates (Marketable Securities) (Details) (USD $) In Thousands, unless otherwise specified	3 Months Ended
	Mar. 31, 2012	Mar. 26, 2011	Dec. 31, 2011
Schedule of Available-for-sale Securities [Line Items]
Realized loss on sale of securities, included in other income (expense)	$ 712	$ 0
Amortized Cost	6,136		17,331
Gross Unrealized Gains	0		0
Gross Unrealized Losses	0		(921)
Fair Value	6,136		16,410
Maturities of debt securities, Amortized Cost
Due less than one year, Amortized Cost	6,136		5,359
Due after one year through five years, Amortized Cost	0		0
Due after ten years, Amortized Cost	0		11,972
Amortized Cost	6,136		17,331
Maturities of debt securities, Fair Value
Dus less than one year, Fair Value	6,136		5,359
Due after one year through five years, Fair Value	0		0
Due after ten years, Fair Value	0		11,051
Time Deposits [Member]
Schedule of Available-for-sale Securities [Line Items]
Amortized Cost	6,136		5,359
Gross Unrealized Gains	0		0
Gross Unrealized Losses	0		0
Fair Value	6,136		5,359
Auction Rate Securities [Member]
Schedule of Available-for-sale Securities [Line Items]
Securities sold for cash	11,260	0
Amortized Cost	0		11,972
Gross Unrealized Gains	0		0
Gross Unrealized Losses	0		(921)
Fair Value	$ 0

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Business Segment Information

3 Months Ended

Mar. 31, 2012

Segment Reporting [Abstract]

Business Segment Information

Business Segment Information

We report two business segments, Research Models and Services (RMS) and Preclinical Services (PCS). Our RMS segment includes sales of research models, genetically engineered models and services (GEMS), insourcing solutions (IS), research animal diagnostic services (RADS), discovery services (DS), in vitro products, and avian vaccine products and services. Our PCS segment includes services required to take a drug through the development process, which include discovery support, safety assessment and biopharmaceutical services.

The following table presents sales and other financial information by business segment.

	Three Months Ended
	March 31, 2012		March 26, 2011
Research Models and Services
Net sales	$	183,152	$	173,371
Gross margin	82,196		73,839
Operating income	59,467		51,742
Depreciation and amortization	8,942		9,269
Capital expenditures	12,900		4,403
Preclinical Services
Net sales	$	102,829	$	112,472
Gross margin	22,016		28,799
Operating income	4,174		9,306
Depreciation and amortization	11,060		11,996
Capital expenditures	1,211		2,387

A reconciliation of segment operating income to consolidated operating income is as follows:

	Three Months Ended
	March 31, 2012			March 26, 2011
Total segment operating income	$	63,641		$	61,048
Unallocated corporate overhead	(19,901		)	(18,797		)
Consolidated operating income	$	43,740		$	42,251

Net sales for each significant service area are as follows:

	Three Months Ended
	March 31, 2012		March 26, 2011
Research models	$	94,021	$	93,400
Research model services	56,331		51,975
Other products	32,800		27,996
Total research models	183,152		173,371
Total preclinical services	102,829		112,472
Total sales	$	285,981	$	285,843

A summary of unallocated corporate overhead consists of the following:

	Three Months Ended
	March 31, 2012		March 26, 2011
Stock-based compensation expense	$	2,785	$	2,986
U.S. retirement plans	1,372		1,057
Audit, tax and related expense	654		755
Salary and bonus	4,923		4,693
Global IT	2,850		2,993
Employee health, long-term disability and fringe benefit expense	1,993		1,639
Consulting and professional services	1,742		1,331
Depreciation expense	1,569		1,581
Other general unallocated corporate expenses	2,013		1,762
Total unallocated corporate overhead costs	$	19,901	$	18,797

Other general unallocated corporate expenses consist of various departmental costs including those associated with departments such as senior executives, corporate accounting, legal, tax, human resources, treasury and investor relations.