X0508 4 2024-05-31 0001100682 CHARLES RIVER LABORATORIES INTERNATIONAL, INC. CRL 0001952784 Parisotto Shannon M C/O CHARLES RIVER LABORATORIES 251 BALLARDVALE STREET WILMINGTON MA 01887 1 CEVP, Disc & Safety Assessment 0 Common Stock 2024-05-31 4 A 0 1727 0 A 8406 D Common Stock 26529 I by Karpathos Investments LLC Stock Options (Right to Buy) 208.44 2024-05-31 4 A 0 3925 208.44 A 2025-05-31 2034-05-31 Common Stock 3925 3925 D Unvested restricted stock units vest as follows: 431 on May 31, 2025, 432 on May 31, 2026, 432 on May 31, 2027, and 432 on May 31, 2028. Stock options vest as follows: 981 on May 31, 2025, 981 on May 31, 2026, 981 on May 31, 2027, and 982 on May 31, 2028. /s/ Shannon M. Parisotto 2024-06-03