X0306 4 2019-03-08 0001100682 CHARLES RIVER LABORATORIES INTERNATIONAL INC CRL 0001767215 LaPlume Joseph W 251 BALLARDVALE STREET WILMINGTON MA 01887 1 EVP, Corp Strategy & Develop Common Stock 2019-03-08 4 S 0 200 137.835 D 20649 D Common Stock 2019-03-08 4 S 0 200 137.85 D 20449 D Common Stock 2019-03-08 4 S 0 99 137.86 D 20350 D Common Stock 2019-03-08 4 S 0 300 137.87 D 20050 D Common Stock 2019-03-08 4 S 0 100 137.88 D 19950 D Common Stock 2019-03-08 4 S 0 100 137.89 D 19850 D Common Stock 2019-03-08 4 S 0 300 137.90 D 19550 D Common Stock 2019-03-08 4 S 0 299 137.91 D 19251 D Common Stock 2019-03-08 4 S 0 200 137.92 D 19051 D Common Stock 2019-03-08 4 S 0 195 137.97 D 18856 D Common Stock 2019-03-08 4 S 0 100 137.98 D 18756 D Common Stock 2019-03-08 4 S 0 230 137.99 D 18526 D Common Stock 2019-03-08 4 S 0 100 138.00 D 18426 D Common Stock 2019-03-08 4 S 0 11 138.01 D 18415 D Common Stock 2019-03-08 4 S 0 5 138.015 D 18410 D Common Stock 2019-03-08 4 S 0 300 138.02 D 18110 D Common Stock 2019-03-08 4 S 0 30 138.025 D 18080 D Common Stock 2019-03-08 4 S 0 300 138.03 D 17780 D Common Stock 2019-03-08 4 S 0 100 138.04 D 17680 D Common Stock 2019-03-08 4 S 0 108 138.05 D 17572 D Common Stock 2019-03-08 4 S 0 60 138.055 D 17512 D Common Stock 2019-03-08 4 S 0 240 138.06 D 17272 D Common Stock 2019-03-08 4 S 0 300 138.07 D 16972 D Common Stock 2019-03-08 4 S 0 600 138.08 D 16372 D Common Stock 2019-03-08 4 S 0 70 138.095 D 16302 D Common Stock 2019-03-08 4 S 0 137 138.10 D 16165 D Common Stock 2019-03-08 4 S 0 200 138.14 D 15965 D Common Stock 2019-03-08 4 S 0 507 138.15 D 15458 D Common Stock 2019-03-08 4 S 0 179 138.16 D 15279 D Common Stock 2019-03-08 4 S 0 200 138.17 D 15079 D /s/ Joseph W. LaPlume 2019-03-11