X0306 4 2019-02-25 0001100682 CHARLES RIVER LABORATORIES INTERNATIONAL INC CRL 0001141722 FOSTER JAMES C 251 BALLARDVALE STREET WILMINGTON MA 01887 1 1 Chairman, President and CEO Common Stock 2019-02-25 4 S 0 111 145.60 D 290609 D Common Stock 2019-02-25 4 S 0 200 145.61 D 290409 D Common Stock 2019-02-25 4 S 0 200 145.615 D 290209 D Common Stock 2019-02-25 4 S 0 75 145.64 D 290134 D Common Stock 2019-02-25 4 S 0 200 145.65 D 289934 D Common Stock 2019-02-25 4 S 0 1 145.66 D 289933 D Common Stock 2019-02-25 4 S 0 400 145.67 D 289533 D Common Stock 2019-02-25 4 S 0 44 145.70 D 289489 D Common Stock 2019-02-25 4 S 0 40 145.705 D 289449 D Common Stock 2019-02-25 4 S 0 5 145.71 D 289444 D Common Stock 2019-02-25 4 S 0 300 145.72 D 289144 D Common Stock 2019-02-25 4 S 0 100 145.73 D 289044 D Common Stock 2019-02-25 4 S 0 200 145.74 D 288844 D Common Stock 2019-02-25 4 S 0 100 145.76 D 288744 D Common Stock 2019-02-25 4 S 0 200 145.82 D 288544 D Common Stock 2019-02-25 4 S 0 200 145.83 D 288344 D Common Stock 2019-02-25 4 S 0 100 145.84 D 288244 D Common Stock 2019-02-25 4 S 0 400 145.86 D 287844 D Common Stock 2019-02-25 4 S 0 100 145.88 D 287744 D Common Stock 2019-02-25 4 S 0 300 145.90 D 287444 D Common Stock 2019-02-25 4 S 0 100 145.91 D 287344 D Common Stock 2019-02-25 4 S 0 600 145.93 D 286744 D Common Stock 2019-02-25 4 S 0 100 145.95 D 286644 D This sale occurred pursuant to a 10b5-1 Trading Plan. /s/ James C. Foster 2019-02-26