X0306 4 2018-07-02 0001100682 CHARLES RIVER LABORATORIES INTERNATIONAL INC CRL 0001141722 FOSTER JAMES C 251 BALLARDVALE STREET WILMINGTON MA 01887 1 1 Chairman & CEO Common Stock 2018-07-02 4 S 0 101 111.25 D 279698 D Common Stock 2018-07-02 4 S 0 99 111.255 D 279599 D Common Stock 2018-07-02 4 S 0 101 111.265 D 279498 D Common Stock 2018-07-02 4 S 0 96 111.27 D 279402 D Common Stock 2018-07-02 4 S 0 400 111.28 D 279002 D Common Stock 2018-07-02 4 S 0 1 111.285 D 279001 D Common Stock 2018-07-02 4 S 0 601 111.29 D 278400 D Common Stock 2018-07-02 4 S 0 1 111.295 D 278399 D Common Stock 2018-07-02 4 S 0 199 111.30 D 278200 D Common Stock 2018-07-02 4 S 0 300 111.305 D 277900 D Common Stock 2018-07-02 4 S 0 300 111.31 D 277600 D Common Stock 2018-07-02 4 S 0 310 111.32 D 277290 D Common Stock 2018-07-02 4 S 0 200 111.33 D 277090 D Common Stock 2018-07-02 4 S 0 100 111.335 D 276990 D Common Stock 2018-07-02 4 S 0 102 111.345 D 276888 D Common Stock 2018-07-02 4 S 0 400 111.36 D 276488 D Common Stock 2018-07-02 4 S 0 200 111.37 D 276288 D Common Stock 2018-07-02 4 S 0 300 111.38 D 275988 D Common Stock 2018-07-02 4 S 0 400 111.39 D 275588 D Common Stock 2018-07-02 4 S 0 243 111.40 D 275345 D Common Stock 2018-07-02 4 S 0 100 111.41 D 275245 D Common Stock 2018-07-02 4 S 0 200 111.42 D 275045 D Common Stock 2018-07-02 4 S 0 494 111.43 D 274551 D Common Stock 2018-07-02 4 S 0 100 111.435 D 274451 D This sale occurred pursuant to a 10b5-1 Trading Plan. /s/ James C. Foster 2018-07-02