X0306 4 2018-02-27 0001100682 CHARLES RIVER LABORATORIES INTERNATIONAL INC CRL 0001141722 FOSTER JAMES C 251 BALLARDVALE STREET WILMINGTON MA 01887 1 1 Chairman & CEO Common Stock 2018-02-27 4 S 0 500 108.26 D 308147 D Common Stock 2018-02-27 4 S 0 200 108.28 D 307947 D Common Stock 2018-02-27 4 S 0 200 108.29 D 307747 D Common Stock 2018-02-27 4 S 0 100 108.295 D 307647 D Common Stock 2018-02-27 4 S 0 16 108.30 D 307631 D Common Stock 2018-02-27 4 S 0 84 108.305 D 307547 D Common Stock 2018-02-27 4 S 0 100 108.31 D 307447 D Common Stock 2018-02-27 4 S 0 300 108.32 D 307147 D Common Stock 2018-02-27 4 S 0 100 108.325 D 307047 D Common Stock 2018-02-27 4 S 0 300 108.33 D 306747 D Common Stock 2018-02-27 4 S 0 100 108.35 D 306647 D Common Stock 2018-02-27 4 S 0 400 108.39 D 306247 D Common Stock 2018-02-27 4 S 0 500 108.395 D 305747 D Common Stock 2018-02-27 4 S 0 200 108.405 D 305547 D Common Stock 2018-02-27 4 S 0 7 108.41 D 305540 D Common Stock 2018-02-27 4 S 0 100 108.42 D 305440 D Common Stock 2018-02-27 4 S 0 500 108.46 D 304940 D Common Stock 2018-02-27 4 S 0 100 108.465 D 304840 D Common Stock 2018-02-27 4 S 0 100 108.505 D 304740 D Common Stock 2018-02-27 4 S 0 200 108.54 D 304540 D Common Stock 2018-02-27 4 S 0 300 108.67 D 304240 D Common Stock 2018-02-27 4 S 0 100 108.69 D 304140 D Common Stock 2018-02-27 4 S 0 100 108.70 D 304040 D Common Stock 2018-02-27 4 S 0 100 108.74 D 303940 D Common Stock 10208 I 2016 GRAT Common Stock 29954 I 2017 GRAT Common Stock 340 I By Trust Common Stock 10000 I Held By Spouse This sale occurred pursuant to a 10b5-1 Trading Plan. /s/ James C. Foster 2018-02-27