X0306 4 2018-02-27 0001100682 CHARLES RIVER LABORATORIES INTERNATIONAL INC CRL 0001141722 FOSTER JAMES C 251 BALLARDVALE STREET WILMINGTON MA 01887 1 1 Chairman & CEO Common Stock 2018-02-27 4 S 0 100 108.03 D 315614 D Common Stock 2018-02-27 4 S 0 300 108.04 D 315314 D Common Stock 2018-02-27 4 S 0 200 108.05 D 315114 D Common Stock 2018-02-27 4 S 0 100 108.055 D 315014 D Common Stock 2018-02-27 4 S 0 300 108.06 D 314714 D Common Stock 2018-02-27 4 S 0 700 108.08 D 314014 D Common Stock 2018-02-27 4 S 0 100 108.085 D 313914 D Common Stock 2018-02-27 4 S 0 200 108.09 D 313714 D Common Stock 2018-02-27 4 S 0 200 108.10 D 313514 D Common Stock 2018-02-27 4 S 0 100 108.105 D 313414 D Common Stock 2018-02-27 4 S 0 200 108.11 D 313214 D Common Stock 2018-02-27 4 S 0 400 108.12 D 312814 D Common Stock 2018-02-27 4 S 0 600 108.13 D 312214 D Common Stock 2018-02-27 4 S 0 267 108.14 D 311947 D Common Stock 2018-02-27 4 S 0 200 108.15 D 311747 D Common Stock 2018-02-27 4 S 0 200 108.17 D 311547 D Common Stock 2018-02-27 4 S 0 500 108.175 D 311047 D Common Stock 2018-02-27 4 S 0 100 108.20 D 310947 D Common Stock 2018-02-27 4 S 0 300 108.205 D 310647 D Common Stock 2018-02-27 4 S 0 300 108.21 D 310347 D Common Stock 2018-02-27 4 S 0 300 108.22 D 310047 D Common Stock 2018-02-27 4 S 0 600 108.23 D 309447 D Common Stock 2018-02-27 4 S 0 300 108.24 D 309147 D Common Stock 2018-02-27 4 S 0 500 108.25 D 308647 D This sale occurred pursuant to a 10b5-1 Trading Plan. /s/ James C. Foster 2018-02-27