X0306 4 2018-02-27 0001100682 CHARLES RIVER LABORATORIES INTERNATIONAL INC CRL 0001141722 FOSTER JAMES C 251 BALLARDVALE STREET WILMINGTON MA 01887 1 1 Chairman & CEO Common Stock 2018-02-27 4 S 0 100 107.815 D 321607 D Common Stock 2018-02-27 4 S 0 260 107.82 D 321347 D Common Stock 2018-02-27 4 S 0 200 107.825 D 321147 D Common Stock 2018-02-27 4 S 0 200 107.83 D 320947 D Common Stock 2018-02-27 4 S 0 500 107.84 D 320447 D Common Stock 2018-02-27 4 S 0 500 107.86 D 319947 D Common Stock 2018-02-27 4 S 0 200 107.87 D 319747 D Common Stock 2018-02-27 4 S 0 200 107.88 D 319547 D Common Stock 2018-02-27 4 S 0 200 107.89 D 319347 D Common Stock 2018-02-27 4 S 0 200 107.90 D 319147 D Common Stock 2018-02-27 4 S 0 300 107.91 D 318847 D Common Stock 2018-02-27 4 S 0 200 107.915 D 318647 D Common Stock 2018-02-27 4 S 0 230 107.92 D 318417 D Common Stock 2018-02-27 4 S 0 100 107.925 D 318317 D Common Stock 2018-02-27 4 S 0 303 107.93 D 318014 D Common Stock 2018-02-27 4 S 0 100 107.935 D 317914 D Common Stock 2018-02-27 4 S 0 100 107.945 D 317814 D Common Stock 2018-02-27 4 S 0 600 107.95 D 317214 D Common Stock 2018-02-27 4 S 0 300 107.955 D 316914 D Common Stock 2018-02-27 4 S 0 300 107.96 D 316614 D Common Stock 2018-02-27 4 S 0 100 107.97 D 316514 D Common Stock 2018-02-27 4 S 0 500 107.99 D 316014 D Common Stock 2018-02-27 4 S 0 200 108.00 D 315814 D Common Stock 2018-02-27 4 S 0 100 108.02 D 315714 D This sale occurred pursuant to a 10b5-1 Trading Plan. /s/ James C. Foster 2018-02-27