X0609 4 2026-06-05 0001100682 CHARLES RIVER LABORATORIES INTERNATIONAL, INC. CRL 0001952784 Parisotto Shannon M false C/O CHARLES RIVER LABORATORIES 251 BALLARDVALE STREET WILMINGTON MA 01887 1 CEVP, Disc & Safety Assessment 0 Common Stock 2026-06-05 4 G 0 1529 0 D 9853 D Common Stock 2026-06-05 4 G 0 1529 0 A 9680 I By Trust Common Stock 28510 I by Karpathos Investments LLC Reflects the exempt transfer pursuant to Rule 16a-13 of 1,529 shares held by the reporting person to a revocable trust controlled by the reporting person. /s/ Shannon M. Parisotto 2026-06-05