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        <name>N/A</name>
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        <name>United Therapeutics Corp.</name>
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        <name>uniQure NV</name>
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        <fairValLevel>1</fairValLevel>
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        <name>ORIC Pharmaceuticals, Inc.</name>
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        <name>Tango Therapeutics, Inc.</name>
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        <name>Quantum-Si, Inc.</name>
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        <name>Amylyx Pharmaceuticals, Inc.</name>
        <lei>N/A</lei>
        <title>Amylyx Pharmaceuticals, Inc.</title>
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        <name>Immuneering Corp.</name>
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        <name>Editas Medicine, Inc.</name>
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        <name>Centessa Pharmaceuticals plc</name>
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        <name>CG oncology, Inc.</name>
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        <name>Inhibrx Biosciences, Inc.</name>
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        <name>Ascendis Pharma A/S</name>
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        <name>Taysha Gene Therapies, Inc.</name>
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        <name>Agios Pharmaceuticals, Inc.</name>
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        <name>Geron Corp.</name>
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        <name>LENZ Therapeutics, Inc.</name>
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        <name>Contra Chinook Therape</name>
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        <name>Immunovant, Inc.</name>
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        <name>Vir Biotechnology, Inc.</name>
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        <name>Prime Medicine, Inc.</name>
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        <name>Maravai LifeSciences Holdings, Inc.</name>
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        <name>NovaBridge Biosciences</name>
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        <name>Mesoblast Ltd.</name>
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        <name>Scholar Rock Holding Corp.</name>
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        <name>Incyte Corp.</name>
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        <name>Immunocore Holdings plc</name>
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        <name>Caris Life Sciences, Inc.</name>
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        <name>Erasca, Inc.</name>
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        <name>Emergent BioSolutions, Inc.</name>
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        <name>Sionna Therapeutics, Inc.</name>
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        <name>Aclaris Therapeutics, Inc.</name>
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        <name>Immutep Ltd.</name>
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        <name>Compass Pathways plc</name>
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        <name>Tyra Biosciences, Inc.</name>
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        <name>Tenaya Therapeutics, Inc.</name>
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        <title>Tenaya Therapeutics, Inc.</title>
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      <invstOrSec>
        <name>Alkermes plc</name>
        <lei>N/A</lei>
        <title>Alkermes plc</title>
        <cusip>N/A</cusip>
        <identifiers>
          <isin value="IE00B56GVS15"/>
          <other otherDesc="Inhouse Asset ID" value="SB3P6D269"/>
        </identifiers>
        <balance>1216662.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>43021168.32000000</valUSD>
        <pctVal>0.529643806396</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>IE</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <loanByFundCondition isLoanByFund="Y" loanVal="654160.00000000"/>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Veracyte, Inc.</name>
        <lei>529900ESWZRHXOW27Z37</lei>
        <title>Veracyte, Inc.</title>
        <cusip>92337F107</cusip>
        <identifiers>
          <isin value="US92337F1075"/>
          <other otherDesc="Inhouse Asset ID" value="SBFTWZY08"/>
        </identifiers>
        <balance>579343.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>18660638.03000000</valUSD>
        <pctVal>0.229735540478</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <loanByFundCondition isLoanByFund="Y" loanVal="10368399.00000000"/>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>N/A</name>
        <lei>N/A</lei>
        <title>E-Mini Health Care Select Sector Index</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Inhouse Asset ID" value="IXCM62024"/>
          <other otherDesc="Future Ticker" value="IXCM6 Index"/>
        </identifiers>
        <balance>53.00000000</balance>
        <units>NC</units>
        <curCd>USD</curCd>
        <valUSD>-73746.73000000</valUSD>
        <pctVal>-0.00090791348</pctVal>
        <payoffProfile>N/A</payoffProfile>
        <assetCat>DE</assetCat>
        <issuerConditional desc="Future" issuerCat="OTHER"/>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <derivativeInfo>
          <futrDeriv derivCat="FUT">
            <counterparties>
              <counterpartyName>CME Clearing House</counterpartyName>
              <counterpartyLei>LCZ7XYGSLJUHFXXNXD88</counterpartyLei>
            </counterparties>
            <payOffProf>Long</payOffProf>
            <descRefInstrmnt>
              <indexBasketInfo>
                <indexName>E-Mini Health Care Select Sector Index</indexName>
                <indexIdentifier>IXV Index</indexIdentifier>
              </indexBasketInfo>
            </descRefInstrmnt>
            <expDate>2026-06-18</expDate>
            <notionalAmt>7899120.00000000</notionalAmt>
            <curCd>USD</curCd>
            <unrealizedAppr>-73746.73000000</unrealizedAppr>
          </futrDeriv>
        </derivativeInfo>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Anavex Life Sciences Corp.</name>
        <lei>549300K1I5L8COCQ8W36</lei>
        <title>Anavex Life Sciences Corp.</title>
        <cusip>032797300</cusip>
        <identifiers>
          <isin value="US0327973006"/>
          <other otherDesc="Inhouse Asset ID" value="032797300"/>
        </identifiers>
        <balance>668447.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>2052132.29000000</valUSD>
        <pctVal>0.025264287320</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <loanByFundCondition isLoanByFund="Y" loanVal="694025.69000000"/>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Akouos, Inc.</name>
        <lei>N/A</lei>
        <title>Akouos, Inc., CVR</title>
        <cusip>009CVR036</cusip>
        <identifiers>
          <isin value="US009CVR0361"/>
          <other otherDesc="Inhouse Asset ID" value="009CVR036"/>
        </identifiers>
        <balance>157087.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1.57000000</valUSD>
        <pctVal>0.000000019328</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetConditional assetCat="OTHER" desc="Right"/>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <loanByFundCondition isLoanByFund="Y" loanVal="1.09890000"/>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Terns Pharmaceuticals, Inc.</name>
        <lei>254900S1ZDQMF4MYP709</lei>
        <title>Terns Pharmaceuticals, Inc.</title>
        <cusip>880881107</cusip>
        <identifiers>
          <isin value="US8808811074"/>
          <other otherDesc="Inhouse Asset ID" value="880881107"/>
        </identifiers>
        <balance>713848.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>37634066.56000000</valUSD>
        <pctVal>0.463321918985</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <loanByFundCondition isLoanByFund="Y" loanVal="3389896.00000000"/>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>OmniAb Operations, Inc.</name>
        <lei>N/A</lei>
        <title>OmniAb, Inc., 12.50 Earnout Shares</title>
        <cusip>68218J202</cusip>
        <identifiers>
          <isin value="US68218J2024"/>
          <other otherDesc="Inhouse Asset ID" value="68218J202"/>
        </identifiers>
        <balance>46839.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>0.47000000</valUSD>
        <pctVal>0.000000005786</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetConditional assetCat="OTHER" desc="Right"/>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Neumora Therapeutics, Inc.</name>
        <lei>N/A</lei>
        <title>Neumora Therapeutics, Inc.</title>
        <cusip>640979100</cusip>
        <identifiers>
          <isin value="US6409791000"/>
          <other otherDesc="Inhouse Asset ID" value="640979100"/>
        </identifiers>
        <balance>421430.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>821788.50000000</valUSD>
        <pctVal>0.010117233124</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>GH Research plc</name>
        <lei>875500HKJS7QQG6EWH62</lei>
        <title>GH Research plc</title>
        <cusip>N/A</cusip>
        <identifiers>
          <isin value="IE000GID8VI0"/>
          <other otherDesc="Inhouse Asset ID" value="SBP6C0S29"/>
        </identifiers>
        <balance>334162.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>4698317.72000000</valUSD>
        <pctVal>0.057842103737</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>IE</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <loanByFundCondition isLoanByFund="Y" loanVal="2879923.86000000"/>
        </securityLending>
      </invstOrSec>
    </invstOrSecs>
    <explntrNotes>




      <explntrNote note="Monthly returns presented in B.5.a have been calculated without deducting any applicable sales loads or redemption fees." noteItem="B.5.a"/>

    </explntrNotes>
    <signature>
      <ncom:dateSigned>2026-03-31</ncom:dateSigned>
      <ncom:nameOfApplicant>iShares Trust</ncom:nameOfApplicant>
      <ncom:signature>Chuck Pulsfort</ncom:signature>
      <ncom:signerName>Chuck Pulsfort</ncom:signerName>
      <ncom:title>Assistant Treasurer</ncom:title>
    </signature>
  </formData>
</edgarSubmission>
