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        <name>Waters Corp.</name>
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        <name>Entrada Therapeutics, Inc.</name>
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        <name>Alpha Teknova, Inc.</name>
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        <title>Alpha Teknova, Inc.</title>
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        <name>Bruker Corp.</name>
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        <name>Twist Bioscience Corp.</name>
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        <name>Illumina, Inc.</name>
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        <name>Galapagos NV</name>
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        <name>Castle Biosciences, Inc.</name>
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        <name>Xenon Pharmaceuticals, Inc.</name>
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        <name>Amicus Therapeutics, Inc.</name>
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        <name>Cullinan Therapeutics, Inc.</name>
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        <name>Perspective Therapeutics, Inc.</name>
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        <name>Ultragenyx Pharmaceutical, Inc.</name>
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        <name>Nuvalent, Inc.</name>
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        <name>Astria Therapeutics, Inc.</name>
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        <name>Codexis, Inc.</name>
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        <name>Natera, Inc.</name>
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        <name>CareDx, Inc.</name>
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        <name>UroGen Pharma Ltd.</name>
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        <name>Mirum Pharmaceuticals, Inc.</name>
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        <name>Kyverna Therapeutics, Inc.</name>
        <lei>N/A</lei>
        <title>Kyverna Therapeutics, Inc.</title>
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        <name>OPKO Health, Inc.</name>
        <lei>529900A4S2D4OGOJLL02</lei>
        <title>OPKO Health, Inc.</title>
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        <name>Beam Therapeutics, Inc.</name>
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      <invstOrSec>
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        <fairValLevel>1</fairValLevel>
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        <name>Humacyte, Inc.</name>
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        <name>ADMA Biologics, Inc.</name>
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        <name>Alvotech SA</name>
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        <fairValLevel>1</fairValLevel>
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        <name>Newamsterdam Pharma Co. NV</name>
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        <name>Crinetics Pharmaceuticals, Inc.</name>
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        <name>Alector, Inc.</name>
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        <name>Arcus Biosciences, Inc.</name>
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        <name>Arvinas, Inc.</name>
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        <name>Geron Corp.</name>
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        <title>Geron Corp.</title>
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        <name>Vanda Pharmaceuticals, Inc.</name>
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        <name>Autolus Therapeutics plc</name>
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        <name>ACADIA Pharmaceuticals, Inc.</name>
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        <name>Vertex Pharmaceuticals, Inc.</name>
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        <name>Cogent Biosciences, Inc.</name>
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        <name>ARS Pharmaceuticals, Inc.</name>
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        <name>REGENXBIO, Inc.</name>
        <lei>549300EOES47LATSET33</lei>
        <title>REGENXBIO, Inc.</title>
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        <invCountry>IT</invCountry>
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        <name>Inozyme Pharma, Inc.</name>
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        <name>Contra Chinook Therape</name>
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        <name>Artiva Biotherapeutics, Inc.</name>
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        <name>GRAIL, Inc.</name>
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        <name>Prime Medicine, Inc.</name>
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        <name>Third Harmonic Bio, Inc.</name>
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        <name>Akero Therapeutics, Inc.</name>
        <lei>549300SI3KG74LBE2955</lei>
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        <name>Maravai LifeSciences Holdings, Inc.</name>
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        <title>Maravai LifeSciences Holdings, Inc., Class A</title>
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        <name>Intellia Therapeutics, Inc.</name>
        <lei>5493002T5BCPE5DZC723</lei>
        <title>Intellia Therapeutics, Inc.</title>
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        <name>BeOne Medicines Ltd.</name>
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        <name>Adaptive Biotechnologies Corp.</name>
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        <name>C4 Therapeutics, Inc.</name>
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        <name>Halozyme Therapeutics, Inc.</name>
        <lei>529900242I3SV9AGM753</lei>
        <title>Halozyme Therapeutics, Inc.</title>
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        <invCountry>US</invCountry>
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        <name>Grifols SA</name>
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        <fairValLevel>1</fairValLevel>
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        <name>Biohaven Ltd.</name>
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        <fairValLevel>1</fairValLevel>
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        <name>Immunocore Holdings plc</name>
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        <fairValLevel>1</fairValLevel>
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        <name>CureVac NV</name>
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        <fairValLevel>1</fairValLevel>
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        <name>OnKure Therapeutics, Inc.</name>
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        <name>BioNTech SE</name>
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        <name>Arbutus Biopharma Corp.</name>
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        <name>Vericel Corp.</name>
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        <name>Trevi Therapeutics, Inc.</name>
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        <name>Nkarta, Inc.</name>
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        <name>Erasca, Inc.</name>
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        <name>Emergent BioSolutions, Inc.</name>
        <lei>549300YW6TUOX8BE5103</lei>
        <title>Emergent BioSolutions, Inc.</title>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>Immutep Ltd.</name>
        <lei>529900OL6C5CY5P8BH38</lei>
        <title>Immutep Ltd.</title>
        <cusip>45257L108</cusip>
        <identifiers>
          <isin value="US45257L1089"/>
          <other otherDesc="Inhouse Asset ID" value="45257L108"/>
        </identifiers>
        <balance>602104.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>987450.56000000</valUSD>
        <pctVal>0.018709471339</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>AU</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <loanByFundCondition isLoanByFund="Y" loanVal="945888.04000000"/>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Compass Pathways plc</name>
        <lei>213800N7CUZIC6QSTZ31</lei>
        <title>Compass Pathways plc</title>
        <cusip>20451W101</cusip>
        <identifiers>
          <isin value="US20451W1018"/>
          <other otherDesc="Inhouse Asset ID" value="20451W101"/>
        </identifiers>
        <balance>332413.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>930756.40000000</valUSD>
        <pctVal>0.017635272989</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>GB</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <loanByFundCondition isLoanByFund="Y" loanVal="851214.00000000"/>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Tyra Biosciences, Inc.</name>
        <lei>N/A</lei>
        <title>Tyra Biosciences, Inc.</title>
        <cusip>90240B106</cusip>
        <identifiers>
          <isin value="US90240B1061"/>
          <other otherDesc="Inhouse Asset ID" value="90240B106"/>
        </identifiers>
        <balance>199507.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1909281.99000000</valUSD>
        <pctVal>0.036175640702</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <loanByFundCondition isLoanByFund="Y" loanVal="1803236.82000000"/>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Moderna, Inc.</name>
        <lei>549300EI6OKH5K5Q2G38</lei>
        <title>Moderna, Inc.</title>
        <cusip>60770K107</cusip>
        <identifiers>
          <isin value="US60770K1079"/>
          <other otherDesc="Inhouse Asset ID" value="60770K107"/>
        </identifiers>
        <balance>2122005.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>58546117.95000000</valUSD>
        <pctVal>1.109287857214</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <loanByFundCondition isLoanByFund="Y" loanVal="33599764.16000000"/>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Dynavax Technologies Corp.</name>
        <lei>549300T5URIXWDILX594</lei>
        <title>Dynavax Technologies Corp.</title>
        <cusip>268158201</cusip>
        <identifiers>
          <isin value="US2681582019"/>
          <other otherDesc="Inhouse Asset ID" value="268158201"/>
        </identifiers>
        <balance>712632.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>7069309.44000000</valUSD>
        <pctVal>0.133943964096</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Alkermes plc</name>
        <lei>N/A</lei>
        <title>Alkermes plc</title>
        <cusip>N/A</cusip>
        <identifiers>
          <isin value="IE00B56GVS15"/>
          <other otherDesc="Inhouse Asset ID" value="SB3P6D269"/>
        </identifiers>
        <balance>999195.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>28586968.95000000</valUSD>
        <pctVal>0.541644410273</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>IE</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Veracyte, Inc.</name>
        <lei>529900ESWZRHXOW27Z37</lei>
        <title>Veracyte, Inc.</title>
        <cusip>92337F107</cusip>
        <identifiers>
          <isin value="US92337F1075"/>
          <other otherDesc="Inhouse Asset ID" value="SBFTWZY08"/>
        </identifiers>
        <balance>478316.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>12928881.48000000</valUSD>
        <pctVal>0.244966732813</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Anavex Life Sciences Corp.</name>
        <lei>549300K1I5L8COCQ8W36</lei>
        <title>Anavex Life Sciences Corp.</title>
        <cusip>032797300</cusip>
        <identifiers>
          <isin value="US0327973006"/>
          <other otherDesc="Inhouse Asset ID" value="032797300"/>
        </identifiers>
        <balance>511493.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>4715965.46000000</valUSD>
        <pctVal>0.089354570430</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <loanByFundCondition isLoanByFund="Y" loanVal="4702375.18000000"/>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Akouos, Inc.</name>
        <lei>N/A</lei>
        <title>Akouos, Inc., CVR</title>
        <cusip>009CVR036</cusip>
        <identifiers>
          <isin value="US009CVR0361"/>
          <other otherDesc="Inhouse Asset ID" value="009CVR036"/>
        </identifiers>
        <balance>157087.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1.57000000</valUSD>
        <pctVal>0.000000029747</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetConditional assetCat="OTHER" desc="Right"/>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <loanByFundCondition isLoanByFund="Y" loanVal="1.09890000"/>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Terns Pharmaceuticals, Inc.</name>
        <lei>254900S1ZDQMF4MYP709</lei>
        <title>Terns Pharmaceuticals, Inc.</title>
        <cusip>880881107</cusip>
        <identifiers>
          <isin value="US8808811074"/>
          <other otherDesc="Inhouse Asset ID" value="880881107"/>
        </identifiers>
        <balance>411652.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1535461.96000000</valUSD>
        <pctVal>0.029092779625</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <loanByFundCondition isLoanByFund="Y" loanVal="163001.00000000"/>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>OmniAb Operations, Inc.</name>
        <lei>N/A</lei>
        <title>OmniAb, Inc.,</title>
        <cusip>68218J202</cusip>
        <identifiers>
          <isin value="US68218J2024"/>
          <other otherDesc="Inhouse Asset ID" value="68218J202"/>
        </identifiers>
        <balance>46839.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>0.47000000</valUSD>
        <pctVal>0.000000008905</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Neumora Therapeutics, Inc.</name>
        <lei>N/A</lei>
        <title>Neumora Therapeutics, Inc.</title>
        <cusip>640979100</cusip>
        <identifiers>
          <isin value="US6409791000"/>
          <other otherDesc="Inhouse Asset ID" value="640979100"/>
        </identifiers>
        <balance>413575.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>303274.55000000</valUSD>
        <pctVal>0.005746218323</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <loanByFundCondition isLoanByFund="Y" loanVal="302401.92050000"/>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Verve Therapeutics, Inc.</name>
        <lei>N/A</lei>
        <title>Verve Therapeutics, Inc.</title>
        <cusip>92539P101</cusip>
        <identifiers>
          <isin value="US92539P1012"/>
          <other otherDesc="Inhouse Asset ID" value="92539P101"/>
        </identifiers>
        <balance>407416.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>4575281.68000000</valUSD>
        <pctVal>0.086688999863</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <loanByFundCondition isLoanByFund="Y" loanVal="117881.31000000"/>
        </securityLending>
      </invstOrSec>
    </invstOrSecs>
    <explntrNotes>




      <explntrNote note="Monthly returns presented in B.5.a have been calculated without deducting any applicable sales loads or redemption fees." noteItem="B.5.a"/>

    </explntrNotes>
    <signature>
      <ncom:dateSigned>2025-06-30</ncom:dateSigned>
      <ncom:nameOfApplicant>iShares Trust</ncom:nameOfApplicant>
      <ncom:signature>Chuck Pulsfort</ncom:signature>
      <ncom:signerName>Chuck Pulsfort</ncom:signerName>
      <ncom:title>Assistant Treasurer</ncom:title>
    </signature>
  </formData>
  <documents>XXXX</documents>
</edgarSubmission>
