POWER OF ATTORNEY





KNOWN ALL MEN BY THESE PRESENTS, that the undersigned hereby constitutes and

appoints CRAIG L. SLUTZKIN as his true and lawful attorney-in-fact and agent for

him and in his name, place and stead, in any and all capacities, to sign any and

all documents relating to any and all Securities and Exchange Commission filings

which may be required, granting unto said attorney-in-fact and agent full power

and authority to do and perform each and every act and thing requisite and

necessary to be done in and about the premises, as fully to all intents and

purposes as he might or could do in person, thereby ratifying and confirming all

that said attorney-in-fact may lawfully do or cause to be done by virtue hereof.





This power shall continue in effect until terminated in writing.





By: /s/ Liam Ratcliffe

 Liam Ratcliffe





Dated: April 9, 2012