X0609 4 2026-04-02 0001099800 Edwards Lifesciences Corp EW 0001196661 BOBO DONALD E JR false ONE EDWARDS WAY IRVINE CA 92614 1 CVP,Strategy/Corp Development 1 Common Stock 2026-04-02 4 M 0 22680.0000 59.2567 A 43946.2532 D Common Stock 2026-04-02 4 S 0 4676.0000 80.5915 D 39270.2532 D Common Stock 2026-04-02 4 S 0 18004.0000 80.0494 D 21266.2532 D Common Stock 38934.6294 I 401(k) Common Stock 121756.0000 I By Trust Employee Stock Option (Right to Acquire) 59.2567 2026-04-02 4 M 0 22680.0000 0.0000 D 2019-06-08 2026-05-07 Common Stock 22680.0000 0.0000 D The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on February 27, 2025. This transaction was executed in multiple trades at prices ranging from $80.510 to $80.660. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide, uponrequest by the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $79.490 to $80.435. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide, uponrequest by the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares and prices at which the transaction was effected. Reflects shares represented on the most recent statement of the Issuer's 401(k) Plan Administrator. This Form 4 reflects changes in beneficial ownership only; it does not identify other securities of the Issuer beneficially owned by the Reporting Person. Linda J. Park, Attorney-in-Fact 2026-04-02