X0306 4 2020-12-17 0 0001098972 AGENUS INC AGEN 0001288123 KLASKIN CHRISTINE M C/O AGENUS INC. 3 FORBES ROAD LEXINGTON MA 02421 0 1 0 0 PFO and PAO Stock Option (Right to buy) 3.7 2020-12-17 4 A 0 50000 0 A 2030-12-17 Common Stock 50000 50000 D Stock Option awarded in accordance with the Agenus Inc. 2019 Equity Incentive Plan. One-third of the Stock Option vests on December 17, 2021, with the remaining vesting in eight equal quarterly installments thereafter (provide Ms. Klaskin maintains a service relationship with the Company through each such vesting date). /s/Evan D. Kearns, as Attorney-in-Fact for Christine M. Klaskin 2020-12-21