X0306 4 2016-03-07 0 0001098972 AGENUS INC AGEN 0000935679 ARMEN GARO H 3 FORBES ROAD LEXINGTON MA 02421 0 1 0 0 Chairman & CEO Common Stock 2016-03-07 4 P 0 200000 4.028 A 1251228 D Dr. Armen's purchase of Agenus Inc. common stock reported herein was matchable under Section 16(b) of the Securities Exchange Act of 1934, with Dr. Armen's sale of an equivalent number of shares of Agenus common stock at a weighted average price of $4.5919 per share on December 28 and December 29, 2015. Dr. Armen has paid to Agenus, as of March 8, 2016, $96,035.81, representing the full amount of the profit realized in connection with the short-swing transaction. Christine M. Klaskin, by Power of Attorney 2016-03-08