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Significant Accounting Policies (Tables)
3 Months Ended
Mar. 31, 2019
Schedule of Estimated Useful Lives of Leasehold Improvements and Equipment [Table Text Block]
  On the declining balance method -  
     
         Laboratory and office equipment 20%
         Computer equipment 30%
     
  On the straight-line method -  
         Leasehold improvements over the lease term
     
  Manufacturing equipment 5 – 10 years