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        <fairValLevel>2</fairValLevel>
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      <invstOrSec>
        <name>Shopify Inc</name>
        <lei>549300HGQ43STJLLP808</lei>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>TransDigm Group Inc</name>
        <lei>N/A</lei>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>Intuit Inc</name>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>Lonza Group AG</name>
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        <invCountry>CH</invCountry>
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        <fairValLevel>2</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>Tesla Inc</name>
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          <ticker value="TSLA"/>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>Etsy Inc</name>
        <lei>54930089Q7XT501AEA40</lei>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>Sea Ltd</name>
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          <ticker value="SE"/>
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        <invCountry>SG</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>Match Group Inc</name>
        <lei>15OMOPB0A8K0EFUVD031</lei>
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          <isin value="US57667L1070"/>
          <ticker value="MTCH"/>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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        <name>S&amp;P Global Inc</name>
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          <ticker value="SPGI"/>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>Align Technology Inc</name>
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        <title>Align Technology Inc</title>
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          <isin value="US0162551016"/>
          <ticker value="ALGN"/>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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        <name>MercadoLibre Inc</name>
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        <title>MercadoLibre Inc</title>
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          <isin value="US58733R1023"/>
          <ticker value="MELI"/>
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        <assetCat>EC</assetCat>
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        <invCountry>AR</invCountry>
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        <fairValLevel>1</fairValLevel>
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        <name>Netflix Inc</name>
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        <title>Netflix Inc</title>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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        <name>Danaher Corp</name>
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        <title>Danaher Corp</title>
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          <ticker value="DHR"/>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <name>Bytedance Ltd Series E-1</name>
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        <assetCat>EP</assetCat>
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        <invCountry>US</invCountry>
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        <name>Zoetis Inc</name>
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        <title>Zoetis Inc</title>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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        <name>MONEY MARKET SERIES LLC</name>
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        <assetCat>STIV</assetCat>
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        <fairValLevel>N/A</fairValLevel>
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        <name>LVMH Moet Hennessy Louis Vuitt</name>
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        <title>LVMH Moet Hennessy Louis Vuitton SE</title>
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          <ticker value="MC"/>
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        <invCountry>FR</invCountry>
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        <name>salesforce.com Inc</name>
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          <ticker value="CRM"/>
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        <name>Amazon.com Inc</name>
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        <name>Alphabet Inc</name>
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        <title>Alphabet Inc</title>
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          <ticker value="GOOGL"/>
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        <name>Adobe Inc</name>
        <lei>FU4LY2G4933NH2E1CP29</lei>
        <title>Adobe Inc</title>
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          <ticker value="ADBE"/>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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        <name>Snap Inc</name>
        <lei>549300JNC0L6VP8A2Q35</lei>
        <title>Snap Inc</title>
        <cusip>83304A106</cusip>
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          <ticker value="SNAP"/>
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        <curCd>USD</curCd>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>Marvell Technology Inc</name>
        <lei>N/A</lei>
        <title>Marvell Technology Inc</title>
        <cusip>573874104</cusip>
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          <isin value="US5738741041"/>
          <ticker value="MRVL"/>
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        <balance>1111243.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>79087164.31000000</valUSD>
        <pctVal>3.599734186745</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Roper Technologies Inc</name>
        <lei>54930003T4SXCIWVXY35</lei>
        <title>Roper Technologies Inc</title>
        <cusip>776696106</cusip>
        <identifiers>
          <isin value="US7766961061"/>
          <ticker value="ROP"/>
        </identifiers>
        <balance>70666.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>32799623.90000000</valUSD>
        <pctVal>1.492908849309</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Meta Platforms Inc</name>
        <lei>BQ4BKCS1HXDV9HN80Z93</lei>
        <title>Meta Platforms Inc</title>
        <cusip>30303M102</cusip>
        <identifiers>
          <isin value="US30303M1027"/>
          <ticker value="FB"/>
        </identifiers>
        <balance>288113.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>93481143.98000000</valUSD>
        <pctVal>4.254891077923</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Copart Inc</name>
        <lei>549300KVYX3JWMYEHU61</lei>
        <title>Copart Inc</title>
        <cusip>217204106</cusip>
        <identifiers>
          <isin value="US2172041061"/>
          <ticker value="CPRT"/>
        </identifiers>
        <balance>282867.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>41060973.72000000</valUSD>
        <pctVal>1.868932741874</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Apple Inc</name>
        <lei>HWUPKR0MPOU8FGXBT394</lei>
        <title>Apple Inc</title>
        <cusip>037833100</cusip>
        <identifiers>
          <isin value="US0378331005"/>
          <ticker value="AAPL"/>
        </identifiers>
        <balance>470456.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>77766376.80000000</valUSD>
        <pctVal>3.539617175411</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Microsoft Corp</name>
        <lei>INR2EJN1ERAN0W5ZP974</lei>
        <title>Microsoft Corp</title>
        <cusip>594918104</cusip>
        <identifiers>
          <isin value="US5949181045"/>
          <ticker value="MSFT"/>
        </identifiers>
        <balance>600536.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>198531196.24000000</valUSD>
        <pctVal>9.036352997046</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>NVIDIA Corp</name>
        <lei>549300S4KLFTLO7GSQ80</lei>
        <title>NVIDIA Corp</title>
        <cusip>67066G104</cusip>
        <identifiers>
          <isin value="US67066G1040"/>
          <ticker value="NVDA"/>
        </identifiers>
        <balance>235887.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>77078436.12000000</valUSD>
        <pctVal>3.508304842925</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Pioneer Natural Resources Co</name>
        <lei>FY8JBF7CCL2VE4F1B628</lei>
        <title>Pioneer Natural Resources Co</title>
        <cusip>723787107</cusip>
        <identifiers>
          <isin value="US7237871071"/>
          <ticker value="PXD"/>
        </identifiers>
        <balance>99515.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>17745514.80000000</valUSD>
        <pctVal>0.807705483491</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ServiceNow Inc</name>
        <lei>549300HJTQM36M0E1G39</lei>
        <title>ServiceNow Inc</title>
        <cusip>81762P102</cusip>
        <identifiers>
          <isin value="US81762P1021"/>
          <ticker value="NOW"/>
        </identifiers>
        <balance>79598.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>51555624.60000000</valUSD>
        <pctVal>2.346607645005</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>NIKE Inc</name>
        <lei>787RXPR0UX0O0XUXPZ81</lei>
        <title>NIKE Inc</title>
        <cusip>654106103</cusip>
        <identifiers>
          <isin value="US6541061031"/>
          <ticker value="NKE"/>
        </identifiers>
        <balance>385133.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>65179908.92000000</valUSD>
        <pctVal>2.966731055226</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Chart Industries Inc</name>
        <lei>EM7QGKC1GYOF3LSZSL80</lei>
        <title>Chart Industries Inc</title>
        <cusip>16115Q308</cusip>
        <identifiers>
          <isin value="US16115Q3083"/>
          <ticker value="GTLS"/>
        </identifiers>
        <balance>222088.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>38765460.40000000</valUSD>
        <pctVal>1.764450075865</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
    </invstOrSecs>
    <explntrNotes>


      <explntrNote note="Monthly returns presented in Item B.5(a) have been calculated without deducting any applicable sales loads or redemption fees." noteItem="B.5.a"/>
    </explntrNotes>
    <signature>
      <ncom:dateSigned>2022-01-25</ncom:dateSigned>
      <ncom:nameOfApplicant>BlackRock Large Cap Focus Growth Fund, Inc.</ncom:nameOfApplicant>
      <ncom:signature>Ann Frechette</ncom:signature>
      <ncom:signerName>Ann Frechette</ncom:signerName>
      <ncom:title>Assistant Treasurer</ncom:title>
    </signature>
  </formData>
</edgarSubmission>
