Statements Of Operations (USD $) In Thousands, except Share data, unless otherwise specified	12 Months Ended
	Dec. 31, 2011	Dec. 31, 2010	Dec. 31, 2009
Revenue:
Net product sales	$ 50,486	$ 35,227	$ 3,585
License and other revenue	25,563
Total revenue	76,049	35,227	3,585
Operating costs and expenses:
Cost of sales, excluding amortization expense	4,510	3,647	408
Cost of license and other revenue	11,698
Research and development	22,189	31,359	32,618
Selling, general and administrative	67,817	78,782	44,448
Amortization of intangible asset	454	454	121
Total operating costs and expenses	106,668	114,242	77,595
Operating loss	(30,619)	(79,015)	(74,010)
Interest and other income, net	85	1,520	380
Loss before income taxes	(30,534)	(77,495)	(73,630)
Income tax benefit	7	78	77
Net loss	$ (30,527)	$ (77,417)	$ (73,553)
Net loss per share: basic and diluted	$ (0.29)	$ (0.74)	$ (0.81)
Weighted average shares: basic and diluted	105,711,536	105,123,420	90,469,720