Cantor Fitzgerald & Co.

499 Park Avenue

New York, NY 10022

March 5, 2021

Securities and Exchange Commission

100 F. Street, N.E.

Washington, D.C. 20549

Re:Portage Biotech Inc. (the "Company")

Registration Statement on Form F-3

File No. 333-253468  

Ladies and Gentlemen:

In accordance with Rule 461 under the Securities Act of 1933, as amended, we hereby join the Company's request for acceleration of the above-referenced Registration Statement, requesting effectiveness be accelerated to 4:30 p.m. Eastern time on Monday, March 8, 2021, or as soon thereafter as practicable.

Very truly yours,

CANTOR FITZGERALD & CO.

By:  /s/ Sameer Vasudev

        Name: Sameer Vasudev

        Title:  Managing Director