<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2008-02-25</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001095274</issuerCik>
        <issuerName>FIRST NATIONAL BANCSHARES INC /SC/</issuerName>
        <issuerTradingSymbol>FNSC</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001245437</rptOwnerCik>
            <rptOwnerName>STERN WILLIAM H</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>8910 TWO NOTCH ROAD</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>COLUMBIA</rptOwnerCity>
            <rptOwnerState>SC</rptOwnerState>
            <rptOwnerZipCode>29223</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common stock (par value $0.01)</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>0</value>
                    <footnoteId id="F1"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <derivativeTable>
        <derivativeHolding>
            <securityTitle>
                <value>Stock options</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>12.09</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <value>2008-01-31</value>
            </exerciseDate>
            <expirationDate>
                <value>2018-01-31</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common stock (par value $0.01)</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>450.61</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeHolding>
        <derivativeHolding>
            <securityTitle>
                <value>Stock options</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>12.43</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <value>2008-01-31</value>
            </exerciseDate>
            <expirationDate>
                <value>2018-01-31</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common stock (par value $0.01)</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>625.28</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeHolding>
        <derivativeHolding>
            <securityTitle>
                <value>Stock options</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>11.08</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <value>2008-01-31</value>
            </exerciseDate>
            <expirationDate>
                <value>2018-01-31</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common stock (par value $0.01)</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>2935.6</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeHolding>
        <derivativeHolding>
            <securityTitle>
                <value>Stock options</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>11.08</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <value>2008-01-31</value>
            </exerciseDate>
            <expirationDate>
                <value>2018-01-31</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common stock (par value $0.01)</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>553.36</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeHolding>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">Ownership is unknown at this time, as the reporting person is awaiting the results of the tabulation and prorating process currently being performed by the issuer's exchange agent, as part of the merger of Carolina National Corporation with and into First National Bancshares, Inc.  Once the results of these calculations are completed, an amended Form 3 will be filed for the reporting person including the number of shares of First National common stock owned.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>William H. Stern</signatureName>
        <signatureDate>2008-03-06</signatureDate>
    </ownerSignature>
</ownershipDocument>
