X0202 4 2005-10-01 0 0001094561 QUOVADX INC QVDX 0001339473 Wilcox Karen 7600 E. ORCHARD RD. SUITE 300S GREENWOOD VILLAGE CO 80111 0 1 0 0 VP of Human Resources Stock Option (Right to Buy) 3.03 2005-10-01 4 A 0 20000 0 A 2012-10-01 Common Stock 20000 20000 D Grant to reporting person of an option to purchase 20,000 shares of Quovadx common stock under the Company's Amended and Restated 1997 Stock Plan at the closing price on Nasdaq on 9/30/2005 because the Nasdaq Stock Market was closed on Saturday, 10/01/2005. The shares underlying the option, listed in column 5 of Table II, shall vest as follows: 25% of the shares subject to the option shall vest on October 1, 2006, and 1/48th of the shares subject to the option shall vest each month thereafter, provided that the reporting person continues to be an employee of the Company on such dates. Linda K. Wackwitz as Attorney-in-Fact for Karen Wilcox 2005-10-04