CONSOLIDATED STATEMENT OF STOCKHOLDERS' EQUITY (DEFICIT) - USD ($)	Common Stock	Additional Paid- in Capital	Accumulated Deficit	Total
Beginning Balance at Dec. 31, 2017	$ 10,616	$ 161,067,538	$ (157,420,027)	$ 3,658,127
Beginning Balance, Shares at Dec. 31, 2017	10,615,724
Issuance of common stock for research and development intellectual property	$ 13,914	116,030,972		116,044,886
Issuance of common stock for research and development intellectual property, Shares	13,914,255
Issuance of common stock and warrants in private placement	$ 18,800	73,101,200		73,120,000
Issuance of common stock and warrants in private placement, Shares	18,800,000
Fees and legal costs relating to private placement		(6,175,000)		(6,175,000)
Stock options exercised for cash	$ 10	18,115		18,125
Stock options exercised for cash, Shares	10,416
Stock options exercised for cash	$ 1,499	4,352,129		4,353,628
Stock options exercised for cash, shares	1,499,324
Stock warrants cashless exercised	$ 280	(280)
Stock warrants cashless exercised, Shares	280,760
Stock-based compensation	$ 329	16,350,263		16,350,592
Stock-based compensation (in shares)	327,786
Repurchase of common stock to pay for employee withholding taxes	$ (8)	(71,702)		(71,710)
Repurchase of common stock to pay for employee withholding taxes, Shares	(7,561)
Fair value of repriced warrants as inducement		727,513	(727,513)
Net loss			(147,957,910)	(147,957,910)
Ending Balance at Dec. 31, 2018	$ 45,440	365,400,748	(306,105,450)	59,340,738
Ending Balance, Shares at Dec. 31, 2018	45,440,704
Stock options exercised for cash	$ 12	57,732		57,744
Stock options exercised for cash, Shares	11,980
Stock options exercised for cash	$ 190	758,543		758,733
Stock options exercised for cash, shares	190,258
Stock warrants cashless exercised	$ 9	(9)
Stock warrants cashless exercised, Shares	9,449
Stock-based compensation	$ 77	5,356,895		5,356,972
Stock-based compensation (in shares)	76,440
Fair value of repriced warrants as inducement				728,000
Net loss			(21,427,964)	(21,427,964)
Ending Balance at Dec. 31, 2019	$ 45,728	$ 371,573,909	$ (327,533,414)	$ 44,086,223
Ending Balance, Shares at Dec. 31, 2019	45,728,831