X0306 4 2012-12-11 0000907562 DYAX CORP DYAX 0001091925 KEMPNER THOMAS L C/O DYAX CORP. 300 TECHNOLOGY SQUARE CAMBRIDGE MA 02139 1 0 0 0 Common Stock 2012-12-11 4 S 0 1417 3.46 D 10375 I By Pinpoint Partners Corporation Common Stock 2012-12-11 4 S 0 3075 3.47 D 7300 I By Pinpoint Partners Corporation Common Stock 1206583 I By Trust Common Stock 1308810 I By Loeb Holding Corporation Common Stock 53764 I By Loeb Investors Co. IX Common Stock 5021 I By spouse Common Stock 27311 D The reporting person is President of Pinpoint Partners Corporation. The reporting person disclaims beneficial ownership of these shares except to the extent of his pecuniary interest therein. Shares held in trust, of which the reporting person is the trustee, for the benefit of the reporting person's brother's children, the reporting person's children, the reporting person's sister-in-law, and the reporting person. The reporting person is the Chairman, Chief Executive Officer, and also beneficial owner of a majority of the voting stock of Loeb Holding Corporation. The reporting person disclaims beneficial ownership of these shares except to the extent of his pecuniary interest therein. The reporting person is the Managing Partner of Loeb Investors Co. IX. The reporting person disclaims beneficial ownership of these shares except to the extent of his pecuniary interest therein. /s/ Nathaniel S. Gardiner, as attorney-in-fact 2012-12-13