X0303 4 2008-12-03 0000793160 IGENE BIOTECHNOLOGY INC IGNE 0001091925 KEMPNER THOMAS L C/O LOEB PARTNERS CORPORATION 61 BROADWAY NEW YORK NY 10006 1 0 1 0 Common Stock 2008-12-03 4 J 0 4717706 A 5368324 D Common Stock 2008-12-03 4 J 0 11206042 A 11206042 I Tte. of Tr. Common Stock 2008-12-03 4 J 0 255139072 A 264160317 I Tte of Tr. Common Stock 110000 I By Spouse Convertible Debentures 0 2008-12-03 4 J 0 22920215 0 D 2012-02-22 Common Stock 22920215 0 I Tte. of Tr. Warrants 0 2008-12-03 4 J 0 44429038 0 D 2012-02-22 Common Stock 44429038 0 I Tte. of Tr. Exchange offer by issuer under Section 3(a)(9) of Securities Act of 1933 to exchange notes and warrants for common stock. Trustee of Trust for the benefit of Carl L. Kempner, Alan H. Kempner, Jr. and Thomas L. Kempner. Trustee of Trust for the benefit of Thomas L. Kempner. Ann Bernhard Kempner. Presently exercisable. /s/ Thomas L. Kempner 2008-12-22