X0202 4 2003-02-28 0000793160 IGENE BIOTECHNOLOGY INC IGNE 0001091925 KEMPNER THOMAS L C/O LOEB PARTNERS CORPORATION 61 BROADWAY NEW YORK NY 10006 1 0 1 0 Common Stock 2002-02-28 4 W 0 162240 0 A 162240 I By Estate Common Stock 2005-09-12 4 J 0 8621247 0 D 0 I Tte. of Tr. Common Stock 2006-06-15 4 P 0 500000 .04 A 9161245 I Tte. of Tr. Common Stock 2006-06-15 4 P 0 100000 .04 A 110000 I By Spouse Common Stock 386972 D Common Stock 182526 I Tte. of Tr. Warrants .075 2002-02-28 4 W 0 87609 .075 A 2008-03-31 Common 87609 42652391 I By estate Warrants .075 2005-09-12 4 J 0 41561125 0 D Common 41561125 42652391 I Tte. of Tr. Convertible Debentures .08 2005-09-12 4 J 0 18761669 0 D 2006-03-31 Common 18761669 19271742 I Tte. of Tr. Estate of Margaret Kempner. Reporting person became an executor on 2/28/02. One half of this amount (81,120 shares) is held as a beneficiary and one half (81,120 shares) is held as trustee of the Trust for the benefit of Rosemary Kempner. The reporting person disclaims beneficial ownership of 81,120 of these securities, and this report shall not be deemed an admission that the reporting person is the beneficial owner of those securities for the purposes of Section 16 or for any other purpose. Tte. of Trust for the benefit of Alan H. Kempner, Jr. Trust corpus distributed to beneficiaries on 9/12/05. Tte. of Trust for the benefit of Thomas L. Kempner. Ann Bernhard Kempner. Spouse previously owned 10,000 shares of stock. Tte. of Trust for the Estate of Nan S. Kempner. Estate of Margaret Kempner. One half of this amount (43,805 shares) is held as a beneficiary and one half (43,804 shares) is held as trustee of the Trust for the benefit of Rosemary Kempner. The reporting person disclaims beneficial ownership of 43,804 of these securities, and this report shall not be deemed an admission that the reporting person is the beneficial owner of those securities for the purposes of Section 16 or for any other purpose. Presently exercisable. Various expiration dates, beginning 3/1/11. /s/ Thomas L. Kempner Attorney-in-fact 2006-06-19