Note 9 - Deferred Revenue	12 Months Ended
Note 9 - Deferred Revenue	Dec. 31, 2016
Notes to Financial Statements
Deferred Revenue Disclosure [Text Block]	Note 9 — Deferred Revenue Deferred revenue consists primarily of prepaid licensing revenue from the Arthrex Agreement. Revenue related to prepaid licensing is recognized on a straight-line basis over five years, the term of the original Arthrex agreement. Revenue of approximately $402,000 related to the prepaid license was recognized in the year ended December 31, 2015. Revenue of approximately $140,000 related to the prepaid license was recognized in the period from January 1, 2016 through May 4, 2016. The remaining balance of deferred revenue of approximately $900,000 related to the prepaid license was recognized against reorganization items in the period from January 1, 2016 through May 4, 2016. See Note 4 – Distribution, Licensing and Collaboration Arrangements for additional details.

The entire disclosure for deferred revenues at the end of the reporting period, and description and amounts of significant changes that occurred during the reporting period. Deferred revenue is a liability as of the balance sheet date related to a revenue producing activity for which revenue has not yet been recognized. Generally, an entity records deferred revenue when it receives consideration from a customer before achieving certain criteria that must be met for revenue to be recognized in conformity with GAAP.