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Geographic information (Details) (USD $)
3 Months Ended 12 Months Ended
Mar. 31, 2013
Mar. 31, 2012
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2010
Revenue from U.S. product sales $ 1,842,800 $ 1,493,400 $ 6,179,000 $ 5,583,300  
Revenue from non-U.S. product sales 410,300 193,000 1,062,400 318,800  
Total revenue from product sales $ 2,253,129 $ 1,686,392 $ 7,241,392 $ 5,902,120 $ 3,787,935