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CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY (DEFICIT) (USD $)
Total
Aldagen Inc [Member]
Common Stock [Member]
Common Stock [Member]
Aldagen Inc [Member]
Additional Paid-In Capital [Member]
Additional Paid-In Capital [Member]
Aldagen Inc [Member]
Retained Earnings [Member]
Common Stock Issuable [Member]
Accumulated Deficit During Development Stage [Member]
Aldagen Inc [Member]
Series A Preferred Stock [Member]
Series B Preferred Stock [Member]
Series D Preferred Stock [Member]
Series E Preferred Stock [Member]
Series A Redeemable Convertible Preferred Stock [Member]
Aldagen Inc [Member]
Series B Redeemable Convertible Preferred Stock [Member]
Aldagen Inc [Member]
Junior Preferred Redeemable Convertible Preferred Stock [Member]
Aldagen Inc [Member]
Series C Redeemable Convertible Preferred Stock [Member]
Aldagen Inc [Member]
Series C-1 Redeemable Convertible Preferred Stock [Member]
Aldagen Inc [Member]
Employees and Directors [Member]
Employees and Directors [Member]
Additional Paid-In Capital [Member]
Other Parties [Member]
Other Parties [Member]
Additional Paid-In Capital [Member]
Promissory Note Payable To JP Nevada Trust [Member]
Additional Paid-In Capital [Member]
Balance at Dec. 31, 1999                                              
Issuance of Series B redeemable convertible preferred stock                           $ 5,942,240                  
Issuance of Series B redeemable convertible preferred stock (in shares)                           6,000,000                  
Issuance of Series B redeemable convertible preferred stock                           5,942,240                  
Issuance of Series B redeemable convertible preferred stock (in shares)                           6,000,000                  
Balance at Dec. 31, 2001                           0                  
Balance (in shares) at Dec. 31, 2001                           6,000,000                  
Balance at Mar. 02, 2000   0   0   0     0         0 0 0 0 0          
Balance (in shares) at Mar. 02, 2000       0                   0 0 0 0 0          
Issuance of restricted common stock to founders at $0.001 per share for cash in April 2000   900   900   0     0         0 0 0 0 0          
Issuance of restricted common stock to founders at $0.001 per share for cash in April 2000 (in shares)       900,000                   0 0 0 0 0          
Net loss attributable to common stockholders   (275,472)   0   0     (275,472)         0 0 0 0 0          
Issuance of common stock to consultants at $0.001 per share for services in April 2000   111   111   0     0         0 0 0 0 0          
Issuance of common stock to consultants at $0.001 per share for services in April 2000 (in shares)       111,000                   0 0 0 0 0          
Issuance of common stock for technology and services at fair value   30,000   300   29,700     0         0 0 0 0 0          
Issuance of common stock for technology and services at fair value (in shares)       300,000                   0 0 0 0 0          
Issuance of restricted common stock to employees at $0.01 per share for cash in September 2000   6,000   600   5,400     0         0 0 0 0 0          
Issuance of restricted common stock to employees at $0.01 per share for cash in September 2000 (in shares)       600,000                   0 0 0 0 0          
Issuance of Series A redeemable convertible preferred stock for cash at $1.00 per share       0                   3,000,000 0 0 0 0          
Issuance of Series A redeemable convertible preferred stock for cash at $1.00 per share (in shares)   0   0   0     0         2,975,029 0 0 0 0          
Revaluation of restricted stock to founders   5,000   0   5,000     0         0 0 0 0 0          
Accretion of redeemable convertible preferred stock   (48,657)   0   (40,100)     (8,557)         48,657 0 0 0 0          
Balance at Dec. 31, 2000   (282,118)   1,911   0     (284,029)         3,023,686 0 0 0 0          
Balance (in shares) at Dec. 31, 2000       1,911,000                   3,000,000 0 0 0 0          
Balance at Mar. 02, 2000   0                                          
Net loss attributable to common stockholders   (70,285,605)                                          
Accretion of redeemable convertible preferred stock   22,978,714                                          
Balance at Dec. 31, 2011   (74,302,306)                                          
Balance at Dec. 31, 2000   (282,118)   1,911   0     (284,029)         3,023,686 0 0 0 0          
Balance (in shares) at Dec. 31, 2000       1,911,000                   3,000,000 0 0 0 0          
Warrants issued pursuant to the Guaranty Agreements executed in connection with the Promissory Note payable   33,721   0   33,721     0         0 0 0 0 0          
Net loss attributable to common stockholders   (1,988,196)   0   0     (1,988,196)         0 0 0 0 0          
Issuance of Series A redeemable convertible preferred stock for cash at $1.00 per share   0   0   0     0         2,967,211 0 0 0 0          
Issuance of Series A redeemable convertible preferred stock for cash at $1.00 per share (in shares)       0                   3,000,000 0 0 0 0          
Revaluation of restricted stock to founders   30,000   0   30,000     0         0 0 0 0 0          
Accretion of redeemable convertible preferred stock   (331,997)   0   (64,456)     (267,541)         331,997 0 0 0 0          
Issuance of preferred stock warrants   33,721   0   33,721     0         0 0 0 0 0          
Beneficial conversion feature   735   0   735     0         0 0 0 0 0          
Issuance of common stock options to consultants for services at fair value       0                   0 0 0 0 0          
Balance at Dec. 31, 2001   (2,537,855)   1,911   0     (2,539,766)         0 0 0 0 0          
Balance (in shares) at Dec. 31, 2001       1,911,000                   6,000,000 0 0 0 0          
Warrants issued pursuant to the Guaranty Agreements executed in connection with the Promissory Note payable   127,500   0   127,500     0         0 0 0 0 0          
Net loss attributable to common stockholders   (3,572,625)   0   0     (3,572,625)         0 0 0 0 0          
Revaluation of restricted stock to founders   60,270   0   60,270     0         0 0 0 0 0          
Accretion of redeemable convertible preferred stock   (489,821)   0   (317,351)     (172,470)         489,821,000 0 0 0 0          
Issuance of preferred stock warrants   127,500   0   127,500     0         0 0 0 0 0          
Beneficial conversion feature   127,500   0   127,500     0         0 0 0 0 0          
Issuance of common stock options to consultants for services at fair value   2,081   0   2,081     0         0 0 0 0 0          
Issuance of common stock options to consultants for services at fair value (in shares)       0                   0 0 0 0 0          
Balance at Dec. 31, 2002   (6,282,950)   1,911   0     (6,284,861)         6,812,715 0 0 0 0          
Balance (in shares) at Dec. 31, 2002       1,911,000                   6,000,000                  
Warrants issued pursuant to the Guaranty Agreements executed in connection with the Promissory Note payable   10,755   0   10,755     0         0 0 0 0 0          
Issuance of Series B redeemable convertible preferred stock   0   0   0     0         0 5,428,018 0 0 0          
Issuance of Series B redeemable convertible preferred stock (in shares)       0                   0 5,497,544 0 0 0          
Net loss attributable to common stockholders   (4,505,763)   0   0     (4,505,763)         0 0 0 0 0          
Revaluation of restricted stock to founders   45,000   0   45,000     0         0 0 0 0 0          
Accretion of redeemable convertible preferred stock   (834,914)   0   (69,984)     (764,930)         487,572 347,342 0 0 0          
Issuance of preferred stock warrants   10,755   0   10,755     0         0 0 0 0 0          
Issuance of common stock options to consultants for services at fair value   14,229   0   14,229     0         0 0 0 0 0          
Issuance of common stock options to consultants for services at fair value (in shares)       0                   0 0 0 0 0          
Conversion of bridge notes and accrued interest into redeemable convertible preferred stock (in shares)       0                   0 761,833 0 0 0          
Issuance of Series B redeemable convertible preferred stock   0   0   0     0         0 5,428,018 0 0 0          
Issuance of Series B redeemable convertible preferred stock (in shares)       0                   0 5,497,544 0 0 0          
Balance at Dec. 31, 2003   (11,553,643)   1,911   0     (11,555,554)         7,300,287 6,537,193 0 0 0          
Balance (in shares) at Dec. 31, 2003       1,911,000                   6,000,000 6,259,377 0 0 0          
Balance at Dec. 31, 2002                           6,812,715                  
Balance (in shares) at Dec. 31, 2002                           6,000,000                  
Issuance of Series B redeemable convertible preferred stock                           9,166,648                  
Issuance of Series B redeemable convertible preferred stock (in shares)                           10,015,000                  
Issuance of Series B redeemable convertible preferred stock                           9,166,648                  
Issuance of Series B redeemable convertible preferred stock (in shares)                           10,015,000                  
Balance at Dec. 31, 2004                           7,787,868                  
Balance (in shares) at Dec. 31, 2004                           6,000,000                  
Balance at Dec. 31, 2003   (11,553,643)   1,911   0     (11,555,554)         7,300,287 6,537,193 0 0 0          
Balance (in shares) at Dec. 31, 2003       1,911,000                   6,000,000 6,259,377 0 0 0          
Warrants issued pursuant to the Guaranty Agreements executed in connection with the Promissory Note payable   8,010   0   8,010     0         0 0 0 0 0          
Issuance of Series B redeemable convertible preferred stock   0   0   0     0         0 3,738,630 0 0 0          
Issuance of Series B redeemable convertible preferred stock (in shares)       0                   0 3,755,623 0 0 0          
Net loss attributable to common stockholders   (4,654,695)   0   0     (4,654,695)         0 0 0 0 0          
Accretion of redeemable convertible preferred stock   (1,119,790)   0   (16,533)     (1,103,257)         0 487,581 632,209 0 0          
Issuance of preferred stock warrants   8,010   0   8,010     0         0 0 0 0 0          
Issuance of common stock options to consultants for services at fair value   8,523   0   8,523     0         0 0 0 0 0          
Issuance of common stock options to consultants for services at fair value (in shares)       0                   0 0 0 0 0          
Issuance of Series B redeemable convertible preferred stock   0   0   0     0         0 3,738,630 0 0 0          
Issuance of Series B redeemable convertible preferred stock (in shares)       0                   0 3,755,623 0 0 0          
Issuance of Junior Preferred                 6,000,000,000                            
Balance at Dec. 31, 2004   (17,311,595)   1,911   0     (17,313,506)         7,787,868 10,908,032 0 0 0          
Balance (in shares) at Dec. 31, 2004       1,911,000                   6,000,000 10,015,000 0 0 0          
Conversion of Series B redeemable convertible preferred stock into common stock   1,500,000   1,500   1,498,500     0         0 (1,500,000) 0 0 0          
Conversion of Series B redeemable convertible preferred stock into common stock (in shares)       1,500,000                   0 (1,500,000) 0 0 0          
Warrants issued pursuant to the Guaranty Agreements executed in connection with the Promissory Note payable   1,282,271   0   1,282,271     0         0 0 0 0 0          
Net loss attributable to common stockholders   (7,134,005)   0   0     (7,134,005)         0 0 0 0 0          
Accretion of redeemable convertible preferred stock   (1,213,974)   0   (1,213,974)     0         487,516 726,458 0 0 0          
Issuance of preferred stock warrants   1,282,271   0   1,282,271     0         0 0 0 0 0          
Issuance of common stock options to consultants for services at fair value   45,975   0   45,975     0         0 169,685 0 0 0          
Issuance of common stock options to consultants for services at fair value (in shares)       0                   0 0 0 0 0          
Conversion of bridge notes and accrued interest into redeemable convertible preferred stock                             (1,500,000,000)                
Conversion of bridge notes and accrued interest into redeemable convertible preferred stock (in shares)                             (1,500,000)                
Elimination of preferred stock dividends upon conversion to common stock   169,685   0   169,685     0         0 1,500,000,000 0 0 0          
Establishment of FAS 150 preferred stock warrant liability   (1,282,271)   0   (1,282,271)     0         0 0 0 0 0          
Balance at Dec. 31, 2005   (23,943,914)   3,411   500,186     (24,447,511)         8,275,384 9,964,805 0 0 0          
Balance (in shares) at Dec. 31, 2005       3,411,000                   6,000,000 8,515,000 0 0 0          
Issuance of restricted common stock to founders at $0.001 per share for cash in April 2000   0   0   0     0         (8,741,917) (10,634,303) 8,302,580 0 0          
Issuance of restricted common stock to founders at $0.001 per share for cash in April 2000 (in shares)       0                   (6,000,000) (8,515,000) 14,515,000 0 0          
Issuance of Series B redeemable convertible preferred stock (in shares)                                 6,518,333            
Net loss attributable to common stockholders   (5,776,177)   0   0     (5,776,177)         0 0 0 0 0          
Accretion of redeemable convertible preferred stock   (1,222,435)   0   (521,334)     (701,101)         466,533 669,498 45,388 41,016 0          
Issuance of common stock options to consultants for services at fair value   0   0   0     0         0 0 0 30,500 0          
Issuance of common stock options to consultants for services at fair value (in shares)       0                   0 0 0 41,907 0          
Conversion of bridge notes and accrued interest into redeemable convertible preferred stock   0   0   0     0         0 0 0 4,331,720 0          
Conversion of bridge notes and accrued interest into redeemable convertible preferred stock (in shares)       0                   0 0 0 5,951,801 0          
Issuance of Series B redeemable convertible preferred stock (in shares)                                 6,518,333            
Elimination of preferred stock dividends upon conversion to common stock                           2,730,083 2,137,462                
Share-based compensation expense   21,148   0   21,148     0         0 0 0 0 0          
Issuance of Series C redeemable convertible preferred stock   0   0   0     0         0 0 0 6,518,333 0          
Issuance of Series C redeemable convertible preferred stock (in shares)       0                   0 0 0 9,131,243 0          
Gain on redemption of certain preferred stock, warrants, and other securities   14,517,817   0   0     14,517,817         0 0 0 0 0          
Balance at Dec. 31, 2006   (16,403,561)   3,411   0     (16,406,972)         0 0 8,347,968 10,921,569 0          
Balance (in shares) at Dec. 31, 2006       3,411,000                   0 0 14,515,000 15,124,951 0          
Issuance of Series B redeemable convertible preferred stock   0   0   0     0         0 0 0 6,904,296 0          
Issuance of Series B redeemable convertible preferred stock (in shares)       0                   0 0 0 9,618,028 0          
Net loss attributable to common stockholders   (6,701,446)   0   0     (6,701,446)         0 0 0 0 0          
Accretion of redeemable convertible preferred stock   (2,119,421)   0   (135,011)     (1,984,410)         0 0 1,035,403 1,084,018 0          
Issuance of Series B redeemable convertible preferred stock   0   0   0     0         0 0 0 6,904,296 0          
Issuance of Series B redeemable convertible preferred stock (in shares)       0                   0 0 0 9,618,028 0          
Share-based compensation expense   93,471   0   93,471               0 0 0 0 0          
Issuance of common stock   41,749   209   41,540     0         0 0 0 0 0          
Issuance of common stock (in shares)   (208,747)   208,747                   0 0 0 0 0          
Balance at Dec. 31, 2007   (25,089,208)   3,620   0     (25,092,828)         0 0 9,383,371 18,909,883 0          
Balance (in shares) at Dec. 31, 2007       3,619,747                   0 0 14,515,000 24,742,979 0          
Issuance of Series B redeemable convertible preferred stock                                   18,321,910,000          
Issuance of Series B redeemable convertible preferred stock (in shares)                                   17,636,655          
Net loss attributable to common stockholders   (10,179,446)   0   0     (10,179,446)         0 0 0 0 0          
Accretion of redeemable convertible preferred stock   (3,588,368)   0   (310,771)     (3,277,597)         0 0 1,038,240 1,492,096 1,058,032          
Issuance of Series B redeemable convertible preferred stock                                   18,321,910,000          
Issuance of Series B redeemable convertible preferred stock (in shares)                                   17,636,655          
Share-based compensation expense   310,771   0   310,771     0         0 0 0 0 0          
Balance at Dec. 31, 2008   (38,546,251)   3,620   0     (38,549,871)         0 0 10,421,611 20,401,979 19,379,942          
Balance (in shares) at Dec. 31, 2008       3,619,747                   0 0 14,515,000 24,742,979 17,636,655          
Net loss attributable to common stockholders   (8,986,202)   0   0     (8,986,202)         0 0 0 0 0          
Accretion of redeemable convertible preferred stock   (4,003,261)   0   (1,179,508)     (2,823,753)         0 0 1,035,403 1,488,133 1,479,725          
Beneficial conversion feature   839,211       839,211                                  
Share-based compensation expense   337,834   0   337,834     0         0 0 0 0 0          
Issuance of common stock   2,468   5   2,463                                  
Issuance of common stock (in shares)   (5,076)   5,076                                      
Balance at Dec. 31, 2009   (50,356,201)   3,625   0     (50,359,826)         0 0 11,457,014 21,890,112 20,859,667          
Balance (in shares) at Dec. 31, 2009       3,624,823                   0 0 14,515,000 24,742,979 17,636,655          
Issuance of Series B redeemable convertible preferred stock   0   0   0     0         0 0 0 0 0          
Issuance of Series B redeemable convertible preferred stock (in shares)       0                   0 0 4,926 0 0          
Net loss attributable to common stockholders   (9,716,014)   0   0     (9,716,014)         0 0 0 0 0          
Accretion of redeemable convertible preferred stock   4,003,265   0   (366,084)     (3,637,181)         0 0 1,035,405 1,488,135 1,479,725          
Issuance of Series B redeemable convertible preferred stock   0   0   0     0         0 0 0 0 0          
Issuance of Series B redeemable convertible preferred stock (in shares)       0                   0 0 4,926 0 0          
Share-based compensation expense   365,089   0   365,089     0         0 0 0 0 0          
Issuance of common stock   0   5   995     0         0 0 0 0 0          
Issuance of common stock (in shares)   (5,000)   5,000                   0 0 0 0 0          
Issuance of Junior Preferred (in shares)                                   0          
Balance at Dec. 31, 2010 (79,252) (63,709,391) 4,410 3,630 47,587,964 0 (47,671,643)   (63,713,021) 10 7     0 0 12,492,419 23,378,247 22,339,392          
Balance (in shares) at Dec. 31, 2010     44,103,743 3,629,823           97,663 65,784 3,315   0 0 14,519,926 24,742,979 17,636,655          
Dividends accrued on Series A, B and D stock (346,236)       (346,236)                                    
Dividends on Series D stock, paid in Common shares 333,556   72   333,484                                    
Dividends on Series D stock, paid in Common shares (in shares)     714,126                                        
Common stock issued upon exercise of August 2009 warrants 191,026   37   190,989                                    
Common stock issued upon exercise of August 2009 warrants (in shares)     374,561                                        
Adjustments of derivative liability for August 2009 warrants exercised and anti-dilutive issuances, net 1,434,322       1,434,322                                    
Write off of deferred financing costs for the August 2009 and October 2010 warrants pursuant to amendments of underlying agreements (136,543)       (136,543)                                    
Warrants issued pursuant to the Guaranty Agreements executed in connection with the Promissory Note payable 545,750                                           545,750
Equity issued pursuant to offering completed 325,000   98   324,902                                    
Equity issued pursuant to offering completed (in shares)     984,850                                        
Conversion of 12% Convertible Promissory Notes completed in Fourth Quarter 2011 769,965   120   769,845                                    
Conversion of 12% Convertible Promissory Notes completed in Fourth Quarter 2011 (in shares)     1,200,000                                        
Stock-based compensation related to options and warrants issued for services rendered                                     241,174 241,174 64,006 64,006  
Dividends on Series D stock, paid in Common shares (in shares)     714,126                                        
Net loss attributable to common stockholders (3,510,515) (6,795,564,000)   0   0 (3,510,515)   (6,795,564,000)         0 0 0 0 0          
Issuance of common stock for technology and services at fair value 0                                            
Accretion of redeemable convertible preferred stock   (4,002,811)   0   (205,460)     (3,797,351)         0 0 1,035,402 1,488,134 1,479,275          
Issuance of preferred stock warrants 545,750                                           545,750
Conversion of bridge notes and accrued interest into redeemable convertible preferred stock (in shares)     34,153                 (15)                      
Share-based compensation expense   205,460   0   205,460     0         0 0 0 0 0          
Issuance of common stock   3,775,000                                          
Balance at Dec. 31, 2011 3,281,583 (74,302,306) 5,554 3,630 54,458,170 0 (51,182,158)   (74,305,936) 10 7     0 0 13,527,821 24,866,381 23,818,667          
Balance (in shares) at Dec. 31, 2011     55,536,292 3,629,823           97,663 65,784 3,300   0 0 14,519,926 24,742,979 17,636,655          
Dividends on Series D stock, paid in Common shares (in shares)     76,461                                        
Adjustments of derivative liability for August 2009 warrants exercised and anti-dilutive issuances, net 0                                            
Write off of deferred financing costs for the August 2009 and October 2010 warrants pursuant to amendments of underlying agreements 0                                            
Equity issued pursuant to offering completed 5,000,000   423   4,999,577                                    
Equity issued pursuant to offering completed (in shares)     4,231,192                                        
Stock-based compensation related to options and warrants issued for services rendered                                     1,751,107 1,751,107 275,924 275,924  
Cash redemption of Series A stock (101,569)       (101,559)         (10)                          
Cash redemption of Series A stock (in shares)                   (97,663)                          
Cash redemption of Series B stock (68,416)       (68,409)           (7)                        
Cash redemption of Series B stock (in shares)                     (65,784)                        
Preferred stock and warrants issued pursuant to Aldagen acquisition completed in First Quarter 1,883,765       1,883,751               14                    
Preferred stock and warrants issued pursuant to Aldagen acquisition completed in First Quarter (in shares)                         135,398                    
Common stock issued to Series D shareholders as inducement to convert outstanding shares 462,000   33   461,967                                    
Common stock issued to Series D shareholders as inducement to convert outstanding shares (in shares)     330,000                                        
Common stock issued upon conversion of Series E stock 34,204,548   1,340   34,203,222               (14)                    
Common stock issued upon conversion of Series E stock (in shares)     13,399,986                   (135,398)                    
Common stock issued upon conversion of 4% Convertible Promissory Note 924,904   106   924,798                                    
Common stock issued upon conversion of 4% Convertible Promissory Note (in shares)     1,062,500                                        
Dividends accrued on Preferred stock (13,562)       (13,562)                                    
Dividends on Series D stock, paid in Common shares 82,500   8   82,492                                    
Dividends on Series D stock, paid in Common shares (in shares)     76,461                                        
Common stock issued upon exercise of Long-term Incentive Plan options 15,185   4   15,181                                    
Common stock issued upon exercise of Long-term Incentive Plan options (in shares)     35,602                                        
Common stock issued upon exercise of August 2008 warrants 584,672   58   584,614                                    
Common stock issued upon exercise of August 2008 warrants (in shares)     584,672                                        
Common stock issued upon exercise of August 2009 warrants 213,674   42   213,632                                    
Common stock issued upon exercise of August 2009 warrants (in shares)     418,968                                        
Common stock issued upon exercise of April 2010 warrants 1,521,028   283   1,520,745                                    
Common stock issued upon exercise of April 2010 warrants (in shares)     2,833,493                                        
Common stock issued upon exercise of Guarantor 2010 warrants 715,734   133   715,601                                    
Common stock issued upon exercise of Guarantor 2010 warrants ( in shares)     1,333,334                                        
Common stock issued upon exercise of October 2010 warrants 225,001   38   224,963                                    
Common stock issued upon exercise of October 2010 warrants (in shares)     375,000                                        
Common stock issued upon exercise of Guarantor 2011 warrants 791,667   158   791,509                                    
Common stock issued upon exercise of Guarantor 2011 warrants (in shares)     1,583,335                                        
Common stock issued in lieu of cash for fees earned by consultant 17,850   2   17,848                                    
Common stock issued in lieu of cash for fees earned by consultant (in shares)     17,500                                        
Common Stock Issuable Value In Lieu Of Cash For Consultant 17,850             17,850                              
Proceeds from Issuance of Private Placement 471,250             471,250         0                    
Net loss attributable to common stockholders (19,798,058)           (19,798,058)                                
Issuance of common stock for technology and services at fair value 30,000                                            
Conversion of bridge notes and accrued interest into redeemable convertible preferred stock (in shares)     7,460,350                 (3,300)                      
Issuance of common stock 15,185                     0 0                    
Issuance of common stock (in shares) 35,602                                            
Balance at Dec. 31, 2012 $ 38,003,911   $ 9,381   $ 108,485,646   $ (70,980,216) $ 489,100                              
Balance (in shares) at Dec. 31, 2012     93,808,386