<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0206</schemaVersion>

    <documentType>3/A</documentType>

    <periodOfReport>2020-04-22</periodOfReport>

    <dateOfOriginalSubmission>2020-05-05</dateOfOriginalSubmission>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001090872</issuerCik>
        <issuerName>AGILENT TECHNOLOGIES, INC.</issuerName>
        <issuerTradingSymbol>A</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001811108</rptOwnerCik>
            <rptOwnerName>MCDONNELL PADRAIG</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>5301 STEVENS CREEK BLVD.</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>SANTA CLARA</rptOwnerCity>
            <rptOwnerState>CA</rptOwnerState>
            <rptOwnerZipCode>95051</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isOfficer>1</isOfficer>
            <officerTitle>Sr. Vice President</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>10791</value>
                    <footnoteId id="F1"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">13,150 shares of common stock of Agilent Technologies, Inc. were reported as beneficially held by the reporting person on a Form 3 filed May 5, 2020. Amended to report the corrected balance of 10,791 shares held beneficially by the reporting person.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ P. Diana Chiu, attorney-in-fact for Mr. McDonnell</signatureName>
        <signatureDate>2022-10-27</signatureDate>
    </ownerSignature>
</ownershipDocument>
