The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
10X Genomics Inc Class A CL A COM 88025U109 67,984 2,387,081 SH   DFND 1 2,387,081 0 0
10X Genomics Inc Class A CL A COM 88025U109 66,721 2,342,738 SH   DFND 2 2,051,170 0 291,568
10X Genomics Inc Class A CL A COM 88025U109 39,546 1,388,561 SH   DFND 3 1,128,997 0 259,564
10X Genomics Inc Class A CL A COM 88025U109 66,216 2,325,008 SH   SOLE 0 2,161,955 0 163,053
1Life Healthcare COM 68269G107 9 537 SH   DFND 3 537 0 0
2U COM 90214J101 2 319 SH   DFND 3 319 0 0
2seventy bio COM 901384107 4 286 SH   DFND 3 286 0 0
8x8 Inc COM 282914100 7 2,045 SH   DFND 3 2,045 0 0
908 Devices COM 65443P102 4 249 SH   DFND 3 249 0 0
A. O. Smith COM 831865209 13 263 SH   DFND 3 263 0 0
ACM Research COM 00108J109 8 660 SH   DFND 3 660 0 0
AJ Gallagher & Co COM 363576109 173,910 1,015,710 SH   DFND 1 1,015,710 0 0
AJ Gallagher & Co COM 363576109 487,316 2,846,139 SH   DFND 2 2,592,724 0 253,415
AJ Gallagher & Co COM 363576109 99,934 583,659 SH   DFND 3 358,349 0 225,310
AJ Gallagher & Co COM 363576109 460,761 2,691,044 SH   SOLE 0 1,770,362 0 920,682
Abcellera Biologics Inc COM 00288U106 45,663 4,617,040 SH   DFND 1 4,617,040 0 0
Abcellera Biologics Inc COM 00288U106 28,491 2,880,740 SH   DFND 2 1,402,118 0 1,478,622
Abcellera Biologics Inc COM 00288U106 40,189 4,063,572 SH   DFND 3 3,269,300 0 794,272
Abcellera Biologics Inc COM 00288U106 17,766 1,796,316 SH   SOLE 0 1,243,900 0 552,416
Abiomed COM 003654100 264,798 1,077,904 SH   DFND 1 1,077,904 0 0
Abiomed COM 003654100 356,275 1,450,276 SH   DFND 2 1,310,627 0 139,649
Abiomed COM 003654100 119,978 488,391 SH   DFND 3 371,054 0 117,337
Abiomed COM 003654100 149,451 608,366 SH   SOLE 0 415,311 0 193,055
Acadia Pharmaceuticals Inc COM 004225108 9 544 SH   DFND 3 544 0 0
Accelerate Diagnostics COM 00430H102 1 418 SH   DFND 3 418 0 0
Accenture 'A' COM G1151C101 12 48 SH   DFND 3 48 0 0
Acutus Medical COM 005111109 0 424 SH   DFND 3 424 0 0
Adaptimmune Therapeutics ADR SPONDS ADR 00653A107 6,511 6,056,564 SH   DFND 1 6,056,564 0 0
Adaptimmune Therapeutics ADR SPONDS ADR 00653A107 3,143 2,923,933 SH   DFND 2 1,145,873 0 1,778,060
Adaptimmune Therapeutics ADR SPONDS ADR 00653A107 1,467 1,364,960 SH   DFND 3 1,364,960 0 0
Adaptimmune Therapeutics ADR SPONDS ADR 00653A107 4,643 4,319,479 SH   SOLE 0 4,319,479 0 0
Adeia Inc COM 00676P107 20 1,448 SH   DFND 3 1,448 0 0
Adicet Bio Inc COM 007002108 1,329 93,449 SH   DFND 1 93,449 0 0
Adicet Bio Inc COM 007002108 1,254 88,177 SH   SOLE 0 88,177 0 0
Adobe Systems COM 00724F101 31,234 113,496 SH   DFND 1 113,496 0 0
Adobe Systems COM 00724F101 99,354 361,024 SH   DFND 2 306,419 0 54,605
Adobe Systems COM 00724F101 20,482 74,425 SH   DFND 3 44,084 0 30,341
Adobe Systems COM 00724F101 94,348 342,836 SH   SOLE 0 223,473 0 119,363
Advanced Micro Devices Inc COM 007903107 7 118 SH   DFND 3 118 0 0
Aerovironment COM 008073108 17,765 213,117 SH   DFND 1 213,117 0 0
Aerovironment COM 008073108 16,199 194,329 SH   DFND 2 77,108 0 117,221
Aerovironment COM 008073108 8,072 96,831 SH   DFND 3 96,831 0 0
Aerovironment COM 008073108 18,386 220,567 SH   SOLE 0 220,567 0 0
Affirm Holdings Inc Class A COM CL A 00827B106 65,644 3,499,152 SH   DFND 1 3,499,152 0 0
Affirm Holdings Inc Class A COM CL A 00827B106 184,353 9,826,945 SH   DFND 2 6,321,609 0 3,505,336
Affirm Holdings Inc Class A COM CL A 00827B106 19,659 1,047,918 SH   DFND 3 852,813 0 195,105
Affirm Holdings Inc Class A COM CL A 00827B106 115,113 6,136,088 SH   SOLE 0 5,170,056 0 966,032
Agios Pharmaceuticals Inc COM 00847X104 5 186 SH   DFND 3 186 0 0
Agnico Eagle Mines COM 008474108 1,116 26,423 SH   DFND 1 26,423 0 0
Agora Inc ADR ADS 00851L103 1,776 489,288 SH   DFND 1 489,288 0 0
Agora Inc ADR ADS 00851L103 926 255,012 SH   SOLE 0 255,012 0 0
Akili Inc COM 00974B107 2,749 1,216,300 SH   DFND 1 1,216,300 0 0
Akili Inc COM 00974B107 7,796 3,449,495 SH   SOLE 0 3,449,495 0 0
Albemarle Corp COM 012653101 161,412 610,393 SH   DFND 1 610,393 0 0
Albemarle Corp COM 012653101 322,548 1,219,740 SH   DFND 2 1,106,058 0 113,682
Albemarle Corp COM 012653101 71,678 271,057 SH   DFND 3 175,847 0 95,210
Albemarle Corp COM 012653101 294,540 1,113,827 SH   SOLE 0 787,653 0 326,174
Alector Inc COM 014442107 619 65,430 SH   DFND 1 65,430 0 0
Alector Inc COM 014442107 1,246 131,752 SH   DFND 2 131,752 0 0
Alector Inc COM 014442107 1,652 174,655 SH   DFND 3 174,655 0 0
Alibaba Group Holding Sponsored ADR SPONSORED ADS 01609W102 2 20 SH   DFND 4 20 0 0
Allbirds Inc COM CL A 01675A109 2,072 681,466 SH   DFND 2 242,231 0 439,235
Allbirds Inc COM CL A 01675A109 2,087 686,619 SH   SOLE 0 686,619 0 0
Alnylam Pharmaceuticals COM 02043Q107 496,471 2,480,373 SH   DFND 1 2,480,373 0 0
Alnylam Pharmaceuticals COM 02043Q107 718,590 3,590,076 SH   DFND 2 3,042,298 0 547,778
Alnylam Pharmaceuticals COM 02043Q107 251,008 1,254,037 SH   DFND 3 977,887 0 276,150
Alnylam Pharmaceuticals COM 02043Q107 438,405 2,190,272 SH   SOLE 0 1,569,541 0 620,731
Alphabet Inc Class A CAP STK CL A 02079K305 5,360 56,035 SH   DFND 1 56,035 0 0
Alphabet Inc Class A CAP STK CL A 02079K305 23,255 243,127 SH   DFND 2 228,787 0 14,340
Alphabet Inc Class A CAP STK CL A 02079K305 1,802 18,838 SH   DFND 3 12,138 0 6,700
Alphabet Inc Class A CAP STK CL A 02079K305 77,069 805,740 SH   SOLE 0 805,740 0 0
Alphabet Inc Class C CAP STK CL C 02079K107 145,835 1,516,741 SH   DFND 1 1,516,741 0 0
Alphabet Inc Class C CAP STK CL C 02079K107 495,681 5,155,288 SH   DFND 2 4,697,715 0 457,573
Alphabet Inc Class C CAP STK CL C 02079K107 97,793 1,017,090 SH   DFND 3 607,433 0 409,657
Alphabet Inc Class C CAP STK CL C 02079K107 385,122 4,005,425 SH   SOLE 0 2,345,079 0 1,660,346
Alteryx Inc COM 02156B103 19 336 SH   DFND 3 336 0 0
Amazon.Com COM 023135106 578,238 5,117,154 SH   DFND 1 5,117,154 0 0
Amazon.Com COM 023135106 2,129,943 18,849,053 SH   DFND 2 11,790,663 0 7,058,390
Amazon.Com COM 023135106 284,466 2,517,402 SH   DFND 3 1,894,935 0 622,467
Amazon.Com COM 023135106 1,256,826 11,122,357 SH   SOLE 0 8,189,655 0 2,932,702
Ambarella SHS G037AX101 15,736 280,100 SH   DFND 1 280,100 0 0
Ambarella SHS G037AX101 7,879 140,240 SH   DFND 2 55,060 0 85,180
Ambarella SHS G037AX101 4,078 72,594 SH   DFND 3 72,594 0 0
Ambarella SHS G037AX101 5,483 97,605 SH   SOLE 0 97,605 0 0
Amdocs COM G02602103 31 386 SH   DFND 3 386 0 0
Ameren COM 023608102 837 10,390 SH   DFND 1 10,390 0 0
American Superconductor Corp COM 030111207 3,168 723,370 SH   DFND 1 723,370 0 0
American Superconductor Corp COM 030111207 3,364 768,000 SH   SOLE 0 768,000 0 0
American Tower Corp REIT COM 03027X100 835 3,890 SH   DFND 1 3,890 0 0
American Well Corp Class A COM 03044L105 30 8,246 SH   DFND 2 8,246 0 0
American Well Corp Class A COM 03044L105 348 97,023 SH   DFND 3 97,023 0 0
Amicus Therapeutics Inc COM 03152W109 6 538 SH   DFND 3 538 0 0
Amkor Technology COM 031652100 30 1,786 SH   DFND 3 1,786 0 0
Analog Devices COM 032654105 88,307 633,754 SH   DFND 1 633,754 0 0
Analog Devices COM 032654105 161,628 1,159,956 SH   DFND 2 1,057,723 0 102,233
Analog Devices COM 032654105 36,563 262,401 SH   DFND 3 174,260 0 88,141
Analog Devices COM 032654105 161,311 1,157,676 SH   SOLE 0 819,611 0 338,065
Anterix COM 03676C100 6 162 SH   DFND 3 162 0 0
Apellis Pharmaceuticals COM 03753U106 19 283 SH   DFND 3 283 0 0
AppFolio COM 03783C100 22 212 SH   DFND 3 212 0 0
Appian Corp CL A 03782L101 86,123 2,109,301 SH   DFND 1 2,109,301 0 0
Appian Corp CL A 03782L101 107,736 2,638,646 SH   DFND 2 2,391,326 0 247,320
Appian Corp CL A 03782L101 9,550 233,906 SH   DFND 3 233,906 0 0
Appian Corp CL A 03782L101 26,271 643,412 SH   SOLE 0 643,412 0 0
Apple COM 037833100 50,792 367,526 SH   DFND 1 367,526 0 0
Apple COM 037833100 391 2,832 SH   DFND 2 0 0 2,832
Apple COM 037833100 7,771 56,231 SH   DFND 3 56,231 0 0
Apple COM 037833100 27,071 195,883 SH   SOLE 0 195,883 0 0
Archer-Daniels-Midland Co COM 039483102 12,454 154,806 SH   DFND 2 154,806 0 0
Archer-Daniels-Midland Co COM 039483102 3,381 42,029 SH   SOLE 0 42,029 0 0
Ares Capital Corp COM 04010L103 32,140 1,904,024 SH   DFND 1 1,904,024 0 0
Ares Capital Corp COM 04010L103 3,529 209,040 SH   DFND 3 209,040 0 0
Ascendis Pharma ADR 1:1 SPON ADR 04351P101 1,587 15,368 SH   DFND 1 15,368 0 0
Ascendis Pharma ADR 1:1 SPON ADR 04351P101 3,284 31,799 SH   DFND 2 31,799 0 0
Ascendis Pharma ADR 1:1 SPON ADR 04351P101 4,268 41,330 SH   DFND 3 41,330 0 0
Asensus Surgical Inc COM 04367G103 2 5,338 SH   DFND 3 5,338 0 0
AstraZeneca ADR COM 046353108 22 400 SH   DFND 3 400 0 0
Atlassian Corp Plc CL A 049468101 95,201 452,068 SH   DFND 1 452,068 0 0
Atlassian Corp Plc CL A 049468101 729,242 3,462,854 SH   DFND 2 1,469,334 0 1,993,520
Atlassian Corp Plc CL A 049468101 106,947 507,846 SH   DFND 3 404,847 0 102,999
Atlassian Corp Plc CL A 049468101 214,897 1,020,453 SH   SOLE 0 465,695 0 554,758
Aurora Innovation Class A Common COM CL A 051774107 33,143 14,996,845 SH   SOLE 0 14,996,845 0 0
AutoZone COM 053332102 4,487 2,095 SH   SOLE 0 2,095 0 0
Avalara Inc COM 05338G106 36 387 SH   DFND 2 387 0 0
Avalara Inc COM 05338G106 421 4,588 SH   DFND 3 4,588 0 0
Avery Dennison Corporation COM 053611109 16 100 SH   DFND 3 100 0 0
Axon Enterprise Inc COM 05464C101 58,896 508,824 SH   DFND 1 508,824 0 0
Axon Enterprise Inc COM 05464C101 114,024 985,087 SH   DFND 2 802,046 0 183,041
Axon Enterprise Inc COM 05464C101 29,486 254,740 SH   DFND 3 186,399 0 68,341
Axon Enterprise Inc COM 05464C101 103,769 896,491 SH   SOLE 0 631,004 0 265,487
Axonics Modulation Technologies COM 05465P101 14 198 SH   DFND 3 198 0 0
Baidu.com Sponsored ADR SPON ADR REP A 056752108 314,796 2,679,345 SH   DFND 2 2,549,871 0 129,474
Banco Bradesco Pn ADR SP ADR PFD NEW 059460303 21,110 5,736,542 SH   DFND 1 5,736,542 0 0
Banco Bradesco Pn ADR SP ADR PFD NEW 059460303 183,255 49,797,451 SH   DFND 2 28,110,842 0 21,686,609
Banco Bradesco Pn ADR SP ADR PFD NEW 059460303 5,705 1,550,241 SH   DFND 3 1,550,241 0 0
Bandwidth COM 05988J103 11 958 SH   DFND 2 958 0 0
Bandwidth COM 05988J103 136 11,463 SH   DFND 3 11,463 0 0
Beam Therapeutics COM 07373V105 5,955 125,009 SH   DFND 1 125,009 0 0
Beam Therapeutics COM 07373V105 4,418 92,740 SH   DFND 2 35,882 0 56,858
Beam Therapeutics COM 07373V105 1,937 40,664 SH   DFND 3 40,664 0 0
Beam Therapeutics COM 07373V105 6,041 126,805 SH   SOLE 0 126,805 0 0
BeiGene Ltd SPONSORED ADR 07725L102 36,680 272,069 SH   DFND 1 272,069 0 0
BeiGene Ltd SPONSORED ADR 07725L102 273,401 2,027,899 SH   DFND 2 848,614 0 1,179,285
BeiGene Ltd SPONSORED ADR 07725L102 40,621 301,301 SH   DFND 3 239,908 0 61,393
BeiGene Ltd SPONSORED ADR 07725L102 82,061 608,672 SH   SOLE 0 276,057 0 332,615
Benefitfocus Inc COM 08180D106 1,946 306,448 SH   DFND 1 306,448 0 0
Benefitfocus Inc COM 08180D106 1,557 245,140 SH   DFND 2 92,742 0 152,398
Benefitfocus Inc COM 08180D106 1,028 161,939 SH   DFND 3 161,939 0 0
Benefitfocus Inc COM 08180D106 1,437 226,368 SH   SOLE 0 226,368 0 0
Berkeley Lights Inc COM 084310101 3,763 1,315,767 SH   DFND 1 1,315,767 0 0
Berkeley Lights Inc COM 084310101 2,107 736,667 SH   DFND 2 515,004 0 221,663
Berkeley Lights Inc COM 084310101 3,472 1,214,076 SH   DFND 3 1,025,115 0 188,961
Berkeley Lights Inc COM 084310101 1,292 451,690 SH   SOLE 0 326,690 0 125,000
Beyond Meat Inc COM 08862E109 61 4,301 SH   DFND 1 4,301 0 0
Beyond Meat Inc COM 08862E109 1 87 SH   DFND 3 87 0 0
BioCryst Pharmaceuticals COM 09058V103 21 1,687 SH   DFND 3 1,687 0 0
BioNTech ADR SPONS ADS 09075V102 75,169 557,306 SH   DFND 1 557,306 0 0
BioNTech ADR SPONS ADS 09075V102 652,704 4,839,149 SH   DFND 2 2,263,746 0 2,575,403
BioNTech ADR SPONS ADS 09075V102 80,244 594,927 SH   DFND 3 498,530 0 96,397
BioNTech ADR SPONS ADS 09075V102 1 7 SH   DFND 4 7 0 0
BioNTech ADR SPONS ADS 09075V102 169,097 1,253,683 SH   SOLE 0 570,493 0 683,190
Biomarin Pharmaceutical Inc COM 09061G101 7 82 SH   DFND 3 82 0 0
Blackline COM 09239B109 19,416 324,138 SH   DFND 1 324,138 0 0
Blackline COM 09239B109 18,766 313,292 SH   DFND 2 122,368 0 190,924
Blackline COM 09239B109 8,930 149,074 SH   DFND 3 149,074 0 0
Blackline COM 09239B109 16,807 280,576 SH   SOLE 0 280,576 0 0
Blackrock Inc COM 09247X101 12 21 SH   DFND 3 21 0 0
Blink Charging COM 09354A100 7 396 SH   DFND 3 396 0 0
Block Inc COM 852234103 6,575 119,566 SH   DFND 2 119,566 0 0
Block Inc COM 852234103 1,880 34,179 SH   SOLE 0 34,179 0 0
Bluebird Bio Inc COM 09609G100 5 860 SH   DFND 3 860 0 0
Blueprint Medicines Corp COM 09627Y109 21 315 SH   DFND 3 315 0 0
Booking Holdings Inc COM 09857L108 59,456 36,183 SH   DFND 1 36,183 0 0
Booking Holdings Inc COM 09857L108 194,581 118,415 SH   DFND 2 107,152 0 11,263
Booking Holdings Inc COM 09857L108 40,477 24,633 SH   DFND 3 14,568 0 10,065
Booking Holdings Inc COM 09857L108 188,309 114,598 SH   SOLE 0 74,638 0 39,960
Boston Omaha COM 101044105 12 529 SH   DFND 3 529 0 0
Box Inc COM 10316T104 23 924 SH   DFND 3 924 0 0
Brady Corp COM 104674106 8 200 SH   DFND 3 200 0 0
BridgeBio Pharma Inc COM 10806X102 854 85,887 SH   DFND 1 85,887 0 0
BridgeBio Pharma Inc COM 10806X102 1,841 185,242 SH   DFND 2 185,242 0 0
BridgeBio Pharma Inc COM 10806X102 2,274 228,760 SH   DFND 3 228,760 0 0
Bristol Myers Squibb COM 110122108 33 458 SH   DFND 3 458 0 0
Broadridge Finl.Sltn. COM 11133T103 64,868 449,471 SH   DFND 1 449,471 0 0
Broadridge Finl.Sltn. COM 11133T103 221,716 1,536,283 SH   DFND 2 1,402,142 0 134,141
Broadridge Finl.Sltn. COM 11133T103 42,029 291,221 SH   DFND 3 171,617 0 119,604
Broadridge Finl.Sltn. COM 11133T103 193,621 1,341,610 SH   SOLE 0 873,078 0 468,532
Brookfield Renewable COM 11284V105 45,814 1,401,882 SH   DFND 1 1,401,882 0 0
Brookfield Renewable COM 11284V105 4,001 122,417 SH   DFND 3 122,417 0 0
Brunswick Corp COM 117043109 14 219 SH   DFND 3 219 0 0
Bumble Inc COM CL A 12047B105 8,596 400,000 SH   SOLE 0 400,000 0 0
Burford Capital ORD SHS G17977110 4,541 610,751 SH   DFND 2 524,917 0 85,834
Burford Capital ORD SHS G17977110 7,527 1,012,394 SH   DFND 1 1,012,394 0 0
Burning Rock Biotech Ltd ADR SPON ADS 12233L107 383 160,181 SH   DFND 1 160,181 0 0
Butterfly Network Inc COM CL A 124155102 1,151 244,892 SH   DFND 1 244,892 0 0
Butterfly Network Inc COM CL A 124155102 1,765 375,532 SH   DFND 2 375,532 0 0
Butterfly Network Inc COM CL A 124155102 3,087 656,806 SH   DFND 3 656,806 0 0
Butterfly Network Inc COM CL A 124155102 3,767 801,558 SH   SOLE 0 801,558 0 0
C3.ai CL A 12468P104 1 117 SH   DFND 3 117 0 0
CEVA Inc COM 157210105 3,588 136,780 SH   DFND 1 136,780 0 0
CEVA Inc COM 157210105 3,295 125,634 SH   DFND 2 48,202 0 77,432
CEVA Inc COM 157210105 1,733 66,080 SH   DFND 3 66,080 0 0
CEVA Inc COM 157210105 2,164 82,500 SH   SOLE 0 82,500 0 0
CH Robinson Worldwide COM NEW 12541W209 35,232 365,822 SH   DFND 1 365,822 0 0
CH Robinson Worldwide COM NEW 12541W209 274 2,847 SH   DFND 2 0 0 2,847
CH Robinson Worldwide COM NEW 12541W209 5,427 56,346 SH   DFND 3 56,346 0 0
CH Robinson Worldwide COM NEW 12541W209 19,372 201,146 SH   SOLE 0 201,146 0 0
CRH Plc ADR ADR 12626K203 3 100 SH   DFND 4 100 0 0
CS Disco Inc COM 126327105 29 2,885 SH   DFND 2 2,885 0 0
CS Disco Inc COM 126327105 344 34,398 SH   DFND 3 34,398 0 0
Calavo Growers Inc COM 128246105 4 113 SH   DFND 3 113 0 0
Calix Inc COM 13100M509 51 832 SH   DFND 2 832 0 0
Calix Inc COM 13100M509 599 9,794 SH   DFND 3 9,794 0 0
Canadian Pacific Railway COM 13645T100 99,466 1,482,172 SH   DFND 2 1,262,772 0 219,400
Cardlytics Inc COM 14161W105 3,703 393,924 SH   DFND 1 393,924 0 0
Cardlytics Inc COM 14161W105 2,672 284,250 SH   DFND 2 112,372 0 171,878
Cardlytics Inc COM 14161W105 1,469 156,270 SH   DFND 3 156,270 0 0
Cardlytics Inc COM 14161W105 2,487 264,524 SH   SOLE 0 264,524 0 0
Cargurus Inc COM 141788109 36 2,532 SH   DFND 2 2,532 0 0
Cargurus Inc COM 141788109 423 29,842 SH   DFND 3 29,842 0 0
Carmax Inc COM 143130102 2,783 42,148 SH   SOLE 0 42,148 0 0
Carvana COM 146869102 35,470 1,747,277 SH   DFND 1 1,747,277 0 0
Carvana COM 146869102 164,940 8,125,106 SH   DFND 2 4,203,501 0 3,921,605
Carvana COM 146869102 20,975 1,033,227 SH   DFND 3 831,331 0 201,896
Carvana COM 146869102 65,740 3,238,448 SH   SOLE 0 2,138,699 0 1,099,749
Castle Biosciences COM 14843C105 6 225 SH   DFND 3 225 0 0
Cbre Group Inc CL A 12504L109 50,601 749,526 SH   DFND 1 749,526 0 0
Cbre Group Inc CL A 12504L109 180,432 2,672,668 SH   DFND 2 2,447,891 0 224,777
Cbre Group Inc CL A 12504L109 32,764 485,317 SH   DFND 3 287,275 0 198,042
Cbre Group Inc CL A 12504L109 152,327 2,256,359 SH   SOLE 0 1,497,790 0 758,569
Cellectis ADR SPONS ADS 15117K103 844 368,752 SH   DFND 1 368,752 0 0
Cellectis ADR SPONS ADS 15117K103 549 239,585 SH   DFND 2 196,962 0 42,623
Cellectis ADR SPONS ADS 15117K103 413 180,500 SH   SOLE 0 180,500 0 0
Celsius Holdings COM 15118V207 23 254 SH   DFND 3 254 0 0
Cemex ADR SPON ADR NEW 151290889 48,505 14,141,362 SH   DFND 1 14,141,362 0 0
Cemex ADR SPON ADR NEW 151290889 169,056 49,287,576 SH   DFND 2 12,141,574 0 37,146,002
Cemex ADR SPON ADR NEW 151290889 58,650 17,099,249 SH   DFND 3 1,824,489 0 15,274,760
Cemex ADR SPON ADR NEW 151290889 2,877 838,813 SH   DFND 4 838,813 0 0
Cemex ADR SPON ADR NEW 151290889 3,546 1,033,870 SH   SOLE 0 1,033,870 0 0
Certara COM 15687V109 18,154 1,367,030 SH   DFND 1 1,367,030 0 0
Certara COM 15687V109 57,540 4,332,831 SH   DFND 2 3,916,950 0 415,881
Certara COM 15687V109 11,790 887,828 SH   DFND 3 522,149 0 365,679
Certara COM 15687V109 56,884 4,283,445 SH   SOLE 0 2,833,450 0 1,449,995
Cerus COM 157085101 5 1,459 SH   DFND 3 1,459 0 0
ChargePoint Holdings Inc COM CL A 15961R105 108 7,310 SH   DFND 1 7,310 0 0
ChargePoint Holdings Inc COM CL A 15961R105 84,843 5,748,141 SH   SOLE 0 5,748,141 0 0
Charles River Laboratories International COM 159864107 11,031 56,054 SH   DFND 2 56,054 0 0
Charles River Laboratories International COM 159864107 10 49 SH   DFND 3 49 0 0
Charles River Laboratories International COM 159864107 3,109 15,796 SH   SOLE 0 15,796 0 0
Charles Schwab COM 808513105 76,683 1,066,965 SH   DFND 1 1,066,965 0 0
Charles Schwab COM 808513105 255,890 3,560,456 SH   DFND 2 3,233,828 0 326,628
Charles Schwab COM 808513105 50,655 704,808 SH   DFND 3 415,618 0 289,190
Charles Schwab COM 808513105 236,816 3,295,062 SH   SOLE 0 2,176,295 0 1,118,767
Chegg COM 163092109 123,721 5,871,913 SH   DFND 1 5,871,913 0 0
Chegg COM 163092109 164,655 7,814,680 SH   DFND 2 6,987,684 0 826,996
Chegg COM 163092109 22,864 1,085,163 SH   DFND 3 858,564 0 226,599
Chegg COM 163092109 72,413 3,436,795 SH   SOLE 0 2,793,710 0 643,085
Chewy Inc CL A 16679L109 118,741 3,865,265 SH   DFND 1 3,865,265 0 0
Chewy Inc CL A 16679L109 241,112 7,848,705 SH   DFND 2 7,460,306 0 388,399
Chewy Inc CL A 16679L109 27,745 903,164 SH   DFND 3 598,769 0 304,395
Chewy Inc CL A 16679L109 123,047 4,005,443 SH   SOLE 0 2,833,835 0 1,171,608
Chinook Therapeutics COM 16961L106 1,814 92,275 SH   DFND 1 92,275 0 0
Chinook Therapeutics COM 16961L106 3,492 177,635 SH   DFND 2 70,453 0 107,182
Chinook Therapeutics COM 16961L106 1,521 77,346 SH   DFND 3 77,346 0 0
Chinook Therapeutics COM 16961L106 2,301 117,058 SH   SOLE 0 117,058 0 0
Church & Dwight Co Inc COM 171340102 13 179 SH   DFND 3 179 0 0
Cisco Systems COM 17275R102 22,967 574,173 SH   DFND 1 574,173 0 0
Cisco Systems COM 17275R102 179 4,482 SH   DFND 2 0 0 4,482
Cisco Systems COM 17275R102 3,530 88,252 SH   DFND 3 88,252 0 0
Cisco Systems COM 17275R102 12,761 319,036 SH   SOLE 0 319,036 0 0
Clear Secure Inc COM 18467V109 22,860 1,000,000 SH   SOLE 0 1,000,000 0 0
Cloudflare Inc CL A COM 18915M107 216,758 3,918,968 SH   DFND 1 3,918,968 0 0
Cloudflare Inc CL A COM 18915M107 751,131 13,580,382 SH   DFND 2 8,538,302 0 5,042,080
Cloudflare Inc CL A COM 18915M107 93,617 1,692,595 SH   DFND 3 1,322,996 0 369,599
Cloudflare Inc CL A COM 18915M107 306,047 5,533,302 SH   SOLE 0 3,608,816 0 1,924,486
Clover Health Investments Corp COM CL A 18914F103 4,497 2,645,503 SH   SOLE 0 2,645,503 0 0
CoStar Group COM 22160N109 229,814 3,299,549 SH   DFND 1 3,299,549 0 0
CoStar Group COM 22160N109 437,121 6,275,968 SH   DFND 2 6,029,404 0 246,564
CoStar Group COM 22160N109 41,559 596,687 SH   DFND 3 407,270 0 189,417
CoStar Group COM 22160N109 192,384 2,762,157 SH   SOLE 0 2,027,057 0 735,100
Coca Cola COM 191216100 22,155 395,489 SH   DFND 1 395,489 0 0
Coca Cola COM 191216100 367 6,559 SH   DFND 2 0 0 6,559
Coca Cola COM 191216100 916 16,349 SH   DFND 3 16,349 0 0
Coca Cola COM 191216100 25,463 454,537 SH   SOLE 0 454,537 0 0
Codexis COM 192005106 16,673 2,751,263 SH   DFND 1 2,751,263 0 0
Codexis COM 192005106 10,702 1,765,972 SH   DFND 2 685,765 0 1,080,207
Codexis COM 192005106 5,522 911,262 SH   DFND 3 833,457 0 77,805
Codexis COM 192005106 9,936 1,639,622 SH   SOLE 0 1,639,622 0 0
Cognizant Technology Solutions Corp CL A 192446102 10 177 SH   DFND 3 177 0 0
Cognyte Software ORD SHS M25133105 1 369 SH   DFND 3 369 0 0
Cohen & Steers Inc COM 19247A100 21 330 SH   DFND 3 330 0 0
Coherent Corp COM 902104108 17 477 SH   DFND 3 477 0 0
Coherus BioSciences COM 19249H103 15 1,585 SH   DFND 3 1,585 0 0
Cohu COM 192576106 18 700 SH   DFND 3 700 0 0
Coinbase Global Inc COM CL A 19260Q107 480 7,447 SH   SOLE 0 7,447 0 0
Commscope Holding Co Inc COM 20337X109 13 1,442 SH   DFND 3 1,442 0 0
Consensus Cloud Solutions COM 20848V105 1 24 SH   DFND 3 24 0 0
Consolidated Edison COM 209115104 34,171 398,453 SH   DFND 1 398,453 0 0
Consolidated Edison COM 209115104 2,377 27,714 SH   DFND 3 27,714 0 0
Cooper Cos Inc/The COM 216648402 8,279 31,373 SH   DFND 2 31,373 0 0
Copa Holdings S A CL A P31076105 27,195 405,829 SH   DFND 1 405,829 0 0
Copa Holdings S A CL A P31076105 242,777 3,623,001 SH   DFND 2 2,372,762 0 1,250,239
Copa Holdings S A CL A P31076105 52,397 781,925 SH   DFND 3 80,052 0 701,873
Copa Holdings S A CL A P31076105 2,314 34,536 SH   DFND 4 34,536 0 0
Corning COM 219350105 20 679 SH   DFND 3 679 0 0
Costco Wholesale Corporation COM 22160K105 30 63 SH   DFND 3 63 0 0
Coupang CL A 22266T109 135,422 8,123,670 SH   DFND 1 8,123,670 0 0
Coupang CL A 22266T109 1,322,884 79,357,144 SH   DFND 2 52,855,898 0 26,501,246
Coupang CL A 22266T109 112,642 6,757,191 SH   DFND 3 4,268,307 0 2,488,884
Coupang CL A 22266T109 365 21,888 SH   DFND 4 21,888 0 0
Coupang CL A 22266T109 236,278 14,173,860 SH   SOLE 0 7,634,199 0 6,539,661
Coursera Inc COM 22266M104 69,575 6,454,065 SH   DFND 1 6,454,065 0 0
Coursera Inc COM 22266M104 75,975 7,047,764 SH   DFND 2 6,412,810 0 634,954
Coursera Inc COM 22266M104 29,043 2,694,145 SH   DFND 3 2,147,099 0 547,046
Coursera Inc COM 22266M104 18,692 1,733,916 SH   SOLE 0 1,357,754 0 376,162
Credicorp COM G2519Y108 19,857 161,701 SH   DFND 1 161,701 0 0
Credicorp COM G2519Y108 105,043 855,401 SH   DFND 2 344,895 0 510,506
Credicorp COM G2519Y108 36,474 297,018 SH   DFND 3 33,509 0 263,509
Credicorp COM G2519Y108 1,771 14,418 SH   DFND 4 14,418 0 0
Crispr Therapeutics Ag REG SHS H17182108 12,562 192,223 SH   DFND 1 192,223 0 0
Crispr Therapeutics Ag REG SHS H17182108 580 8,880 SH   DFND 2 8,880 0 0
Crispr Therapeutics Ag REG SHS H17182108 841 12,862 SH   DFND 3 8,803 0 4,059
Crispr Therapeutics Ag REG SHS H17182108 4,874 74,588 SH   SOLE 0 74,588 0 0
CrowdStrike Holdings COM 22788C105 19 114 SH   DFND 3 114 0 0
Cullen/Frost Bankers COM 229899109 27,570 208,513 SH   DFND 1 208,513 0 0
Cullen/Frost Bankers COM 229899109 211 1,599 SH   DFND 2 0 0 1,599
Cullen/Frost Bankers COM 229899109 4,272 32,308 SH   DFND 3 32,308 0 0
Cullen/Frost Bankers COM 229899109 14,950 113,069 SH   SOLE 0 113,069 0 0
CyberArk Software Ltd SHS M2682V108 9,317 62,138 SH   DFND 1 62,138 0 0
CyberArk Software Ltd SHS M2682V108 19,979 133,246 SH   DFND 2 52,228 0 81,018
CyberArk Software Ltd SHS M2682V108 9,891 65,968 SH   DFND 3 65,968 0 0
CyberArk Software Ltd SHS M2682V108 14,122 94,184 SH   SOLE 0 94,184 0 0
Cytokinetics Inc COM NEW 23282W605 16 340 SH   DFND 3 340 0 0
Dada Nexus Ltd ADR ADS 23344D108 12,082 2,554,240 SH   DFND 1 2,554,240 0 0
Dada Nexus Ltd ADR ADS 23344D108 5,531 1,169,302 SH   DFND 2 1,169,302 0 0
Dada Nexus Ltd ADR ADS 23344D108 188 39,726 SH   DFND 3 39,726 0 0
Dada Nexus Ltd ADR ADS 23344D108 3,702 782,705 SH   SOLE 0 782,705 0 0
Datadog COM 23804L103 127,250 1,433,316 SH   DFND 1 1,433,316 0 0
Datadog COM 23804L103 249,245 2,807,443 SH   DFND 2 2,679,258 0 128,185
Datadog COM 23804L103 26,981 303,907 SH   DFND 3 200,722 0 103,185
Datadog COM 23804L103 121,564 1,369,270 SH   SOLE 0 969,886 0 399,384
Deere & Co COM 244199105 155,934 467,022 SH   DFND 1 467,022 0 0
Deere & Co COM 244199105 92,428 276,823 SH   DFND 2 166,318 0 110,505
Deere & Co COM 244199105 160,455 480,562 SH   DFND 3 374,659 0 105,903
Deere & Co COM 244199105 40,949 122,642 SH   SOLE 0 51,564 0 71,078
Denali Therapeutics COM 24823R105 87,993 2,867,152 SH   DFND 1 2,867,152 0 0
Denali Therapeutics COM 24823R105 129,016 4,203,856 SH   DFND 2 4,085,465 0 118,391
Denali Therapeutics COM 24823R105 12,306 400,981 SH   DFND 3 362,361 0 38,620
Denali Therapeutics COM 24823R105 222,290 7,243,062 SH   SOLE 0 7,243,062 0 0
DermTech COM 24984K105 1 286 SH   DFND 3 286 0 0
Dexcom Inc COM 252131107 225,527 2,800,191 SH   DFND 1 2,800,191 0 0
Dexcom Inc COM 252131107 751,687 9,333,085 SH   DFND 2 4,109,529 0 5,223,556
Dexcom Inc COM 252131107 245,685 3,050,469 SH   DFND 3 2,432,167 0 618,302
Dexcom Inc COM 252131107 235,292 2,921,433 SH   SOLE 0 1,311,859 0 1,609,574
Digimarc COM 25381B101 3,556 262,445 SH   DFND 1 262,445 0 0
Digimarc COM 25381B101 3,229 238,316 SH   DFND 2 95,317 0 142,999
Digimarc COM 25381B101 1,696 125,165 SH   DFND 3 125,165 0 0
Digimarc COM 25381B101 2,096 154,711 SH   SOLE 0 154,711 0 0
Digital Realty Trust REIT COM 253868103 406 4,094 SH   DFND 1 4,094 0 0
Docebo COM 25609L105 4,435 163,381 SH   DFND 2 140,600 0 22,781
Docebo COM 25609L105 7 267 SH   DFND 3 267 0 0
Dolby Laboratories 'A' COM 25659T107 17,799 273,202 SH   DFND 1 273,202 0 0
Dolby Laboratories 'A' COM 25659T107 141 2,157 SH   DFND 2 0 0 2,157
Dolby Laboratories 'A' COM 25659T107 2,729 41,892 SH   DFND 3 41,892 0 0
Dolby Laboratories 'A' COM 25659T107 13,271 203,702 SH   SOLE 0 203,702 0 0
Dollar General Corp COM 256677105 15 62 SH   DFND 3 62 0 0
Domo COM 257554105 6 321 SH   DFND 3 321 0 0
Donaldson COM 257651109 21 436 SH   DFND 3 436 0 0
Doordash Inc COM 25809K105 77,929 1,575,925 SH   DFND 1 1,575,925 0 0
Doordash Inc COM 25809K105 158,052 3,196,206 SH   DFND 2 3,036,838 0 159,368
Doordash Inc COM 25809K105 18,537 374,865 SH   DFND 3 246,251 0 128,614
Doordash Inc COM 25809K105 131,015 2,649,437 SH   SOLE 0 2,156,318 0 493,119
Doximity Inc CLASS A 26622P107 8,766 290,088 SH   DFND 1 290,088 0 0
Doximity Inc CLASS A 26622P107 2,383 78,866 SH   DFND 2 78,866 0 0
Doximity Inc CLASS A 26622P107 3,286 108,730 SH   DFND 3 108,730 0 0
Doximity Inc CLASS A 26622P107 7,274 240,718 SH   SOLE 0 240,718 0 0
DraftKings Inc COM CL A 26142V105 18 1,214 SH   DFND 3 1,214 0 0
Dropbox CL A 26210C104 18 881 SH   DFND 3 881 0 0
Duck Creek Technologies SHS 264120106 4 355 SH   DFND 3 355 0 0
Duke Realty Corporation REIT COM 264411505 13,263 275,165 SH   DFND 1 275,165 0 0
Duke Realty Corporation REIT COM 264411505 1,197 24,835 SH   DFND 3 24,835 0 0
Duolingo Inc CL A COM 26603R106 108,010 1,134,200 SH   DFND 1 1,134,200 0 0
Duolingo Inc CL A COM 26603R106 108,267 1,136,895 SH   DFND 2 1,011,322 0 125,573
Duolingo Inc CL A COM 26603R106 50,763 533,058 SH   DFND 3 422,642 0 110,416
Duolingo Inc CL A COM 26603R106 25,274 265,400 SH   SOLE 0 190,275 0 75,125
EHang Holdings Ltd ADR ADS 26853E102 13 3,105 SH   DFND 1 3,105 0 0
Eargo COM 270087109 0 263 SH   DFND 3 263 0 0
Ecolab COM 278865100 57,832 400,440 SH   DFND 1 400,440 0 0
Ecolab COM 278865100 36,963 255,942 SH   DFND 2 160,832 0 95,110
Ecolab COM 278865100 59,832 414,293 SH   DFND 3 321,649 0 92,644
Ecolab COM 278865100 13,506 93,519 SH   SOLE 0 32,412 0 61,107
Edwards Lifesciences Corp COM 28176E108 3,609 43,682 SH   DFND 1 43,682 0 0
Edwards Lifesciences Corp COM 28176E108 19,091 231,040 SH   DFND 2 231,040 0 0
Edwards Lifesciences Corp COM 28176E108 9,662 116,929 SH   DFND 3 116,929 0 0
Edwards Lifesciences Corp COM 28176E108 3,346 40,495 SH   SOLE 0 40,495 0 0
Elastic ORD SHS N14506104 347,776 4,847,733 SH   DFND 2 4,101,783 0 745,950
Electronic Arts, Inc. COM 285512109 20 170 SH   DFND 3 170 0 0
Electronic Arts, Inc. COM 285512109 4,082 35,276 SH   SOLE 0 35,276 0 0
Elevance Health Inc COM 036752103 219,913 484,133 SH   DFND 1 484,133 0 0
Elevance Health Inc COM 036752103 738,809 1,626,472 SH   DFND 2 1,478,738 0 147,734
Elevance Health Inc COM 036752103 148,151 326,151 SH   DFND 3 193,901 0 132,250
Elevance Health Inc COM 036752103 698,628 1,538,015 SH   SOLE 0 1,011,334 0 526,681
Emergent Biosolutions Inc COM 29089Q105 8 385 SH   DFND 3 385 0 0
Enanta Pharmaceuticals COM 29251M106 16 318 SH   DFND 3 318 0 0
Enphase Energy Inc COM 29355A107 299 1,076 SH   DFND 1 1,076 0 0
Enphase Energy Inc COM 29355A107 26 92 SH   DFND 3 92 0 0
Estee Lauder 'A' COM 518439104 70,362 325,900 SH   DFND 1 325,900 0 0
Estee Lauder 'A' COM 518439104 245,221 1,135,810 SH   DFND 2 1,037,727 0 98,083
Estee Lauder 'A' COM 518439104 46,143 213,723 SH   DFND 3 127,163 0 86,560
Estee Lauder 'A' COM 518439104 220,136 1,019,622 SH   SOLE 0 673,944 0 345,678
EverQuote Inc COM CL A 30041R108 4,903 718,967 SH   DFND 1 718,967 0 0
EverQuote Inc COM CL A 30041R108 1,532 224,695 SH   DFND 2 88,851 0 135,844
EverQuote Inc COM CL A 30041R108 1,056 154,853 SH   DFND 3 154,853 0 0
EverQuote Inc COM CL A 30041R108 1,579 231,550 SH   SOLE 0 231,550 0 0
Everbridge Inc COM 29978A104 8,315 269,259 SH   DFND 1 269,259 0 0
Everbridge Inc COM 29978A104 5,280 170,985 SH   DFND 2 67,609 0 103,376
Everbridge Inc COM 29978A104 2,682 86,847 SH   DFND 3 86,847 0 0
Everbridge Inc COM 29978A104 4,584 148,446 SH   SOLE 0 148,446 0 0
Eversource Energy COM 30040W108 28,925 371,026 SH   DFND 1 371,026 0 0
Eversource Energy COM 30040W108 2,049 26,289 SH   DFND 3 26,289 0 0
Exact Sciences COM 30063P105 36,262 1,116,082 SH   DFND 1 1,116,082 0 0
Exact Sciences COM 30063P105 51,930 1,598,336 SH   DFND 2 1,145,984 0 452,352
Exact Sciences COM 30063P105 19,045 586,189 SH   DFND 3 483,682 0 102,507
Exact Sciences COM 30063P105 49,145 1,512,630 SH   SOLE 0 1,178,347 0 334,283
Exelixis COM 30161Q104 19 1,230 SH   DFND 3 1,230 0 0
Exelon Corporation COM 30161N101 856 22,861 SH   DFND 1 22,861 0 0
Expedia Group Inc COM 30212P303 16 176 SH   DFND 3 176 0 0
Expeditors Intl COM 302130109 9 107 SH   DFND 3 107 0 0
Expensify Inc COM CL A 30219Q106 10,374 697,160 SH   DFND 1 697,160 0 0
Expensify Inc COM CL A 30219Q106 36 2,416 SH   DFND 2 2,416 0 0
Expensify Inc COM CL A 30219Q106 420 28,200 SH   DFND 3 28,200 0 0
Expensify Inc COM CL A 30219Q106 5,344 359,144 SH   SOLE 0 359,144 0 0
Exponent COM 30214U102 21 242 SH   DFND 3 242 0 0
Exscientia Ltd ADR ADS 30223G102 8,801 1,072,017 SH   DFND 1 1,072,017 0 0
Exscientia Ltd ADR ADS 30223G102 15,287 1,861,945 SH   DFND 2 215,124 0 1,646,821
Exscientia Ltd ADR ADS 30223G102 1,665 202,782 SH   DFND 3 202,782 0 0
Exscientia Ltd ADR ADS 30223G102 14,303 1,742,192 SH   SOLE 0 958,159 0 784,033
FTI Consulting COM 302941109 4,874 29,413 SH   SOLE 0 29,413 0 0
Factset Research Systems COM 303075105 24 61 SH   DFND 3 61 0 0
Farfetch ORD SHS CL A 30744W107 44,344 5,952,189 SH   DFND 1 5,952,189 0 0
Farfetch ORD SHS CL A 30744W107 162,159 21,766,314 SH   DFND 2 18,071,971 0 3,694,343
Farfetch ORD SHS CL A 30744W107 19,830 2,661,809 SH   DFND 3 1,685,574 0 976,235
Farfetch ORD SHS CL A 30744W107 119,333 16,017,809 SH   SOLE 0 10,111,219 0 5,906,590
Fastenal COM 311900104 74,773 1,624,091 SH   DFND 1 1,624,091 0 0
Fastenal COM 311900104 14,250 309,521 SH   DFND 2 239,770 0 69,751
Fastenal COM 311900104 13,403 291,112 SH   DFND 3 262,836 0 28,276
Fastenal COM 311900104 38,778 842,260 SH   SOLE 0 842,260 0 0
Fastly CL A 31188V100 2 205 SH   DFND 3 205 0 0
Fate Therapeutics COM 31189P102 8 372 SH   DFND 3 372 0 0
Ferrari NV COM N3167Y103 1,467,606 7,814,773 SH   DFND 2 6,068,572 0 1,746,201
Ferrari NV COM N3167Y103 255,392 1,359,921 SH   SOLE 0 1,359,921 0 0
Fibrogen Inc COM 31572Q808 6 467 SH   DFND 3 467 0 0
First Industrial REIT COM 32054K103 31,912 712,153 SH   DFND 1 712,153 0 0
First Industrial REIT COM 32054K103 3,606 80,463 SH   DFND 3 80,463 0 0
First Republic Bank COM 33616C100 122,515 938,456 SH   DFND 1 938,456 0 0
First Republic Bank COM 33616C100 192,122 1,471,637 SH   DFND 2 1,429,430 0 42,207
First Republic Bank COM 33616C100 10,659 81,649 SH   DFND 3 67,542 0 14,107
First Republic Bank COM 33616C100 27,100 207,585 SH   SOLE 0 207,585 0 0
Fiverr Intl ORD SHS M4R82T106 10,513 343,683 SH   DFND 1 343,683 0 0
Fiverr Intl ORD SHS M4R82T106 7,756 253,559 SH   DFND 2 99,021 0 154,538
Fiverr Intl ORD SHS M4R82T106 3,807 124,439 SH   DFND 3 124,439 0 0
Fiverr Intl ORD SHS M4R82T106 9,895 323,476 SH   SOLE 0 323,476 0 0
Fortis COM 349553107 802 20,990 SH   DFND 1 20,990 0 0
Fortive Corp COM 34959J108 5,703 97,814 SH   DFND 2 97,814 0 0
Fox COM 35137L105 11 362 SH   DFND 3 362 0 0
Freshpet Inc COM 358039105 33 655 SH   DFND 2 655 0 0
Freshpet Inc COM 358039105 383 7,643 SH   DFND 3 7,643 0 0
Full Truck Alliance Co Ltd ADR SPONS ADS 35969L108 103,953 15,870,755 SH   DFND 2 15,421,121 0 449,634
Futu Hdgs ADR SPON ADR CL A 36118L106 41,941 1,124,724 SH   DFND 2 880,342 0 244,382
Futu Hdgs ADR SPON ADR CL A 36118L106 0 12 SH   DFND 4 12 0 0
GAN COM G3728V109 1 572 SH   DFND 3 572 0 0
Gentex Corp COM 371901109 12 516 SH   DFND 3 516 0 0
Ginkgo Bioworks Holdings Inc CL A COM 37611X100 64,006 20,514,676 SH   DFND 1 20,514,676 0 0
Ginkgo Bioworks Holdings Inc CL A COM 37611X100 209,722 67,218,616 SH   DFND 2 40,156,587 0 27,062,029
Ginkgo Bioworks Holdings Inc CL A COM 37611X100 22,767 7,297,136 SH   DFND 3 5,942,260 0 1,354,876
Ginkgo Bioworks Holdings Inc CL A COM 37611X100 340,225 109,046,415 SH   SOLE 0 101,674,875 0 7,371,540
GitLab CLASS A 37637K108 3,308 64,583 SH   SOLE 0 64,583 0 0
Glaukos Corp COM 377322102 14 269 SH   DFND 3 269 0 0
Global Blood Therapeutics Inc COM 37890U108 61 892 SH   DFND 3 892 0 0
Globus Medical CL A 379577208 3,817 64,077 SH   SOLE 0 64,077 0 0
Golub Capital BDC Inc COM 38173M102 1,513 122,100 SH   DFND 1 122,100 0 0
Goodyear Tire & Rubber Co/The COM 382550101 15 1,525 SH   DFND 3 1,525 0 0
Graco COM 384109104 22 363 SH   DFND 3 363 0 0
Grainger, WW COM 384802104 29 60 SH   DFND 3 60 0 0
HDFC Bank ADR ADR REPS 3 SHS 40415F101 60,767 1,040,183 SH   DFND 2 894,959 0 145,224
HDFC Bank ADR ADR REPS 3 SHS 40415F101 11,118 190,305 SH   DFND 3 132,622 0 57,683
HDFC Bank ADR ADR REPS 3 SHS 40415F101 107,113 1,833,502 SH   SOLE 0 1,205,040 0 628,462
HUYA ADR ADS REP SHS A 44852D108 2,541 1,144,570 SH   DFND 1 1,144,570 0 0
HUYA ADR ADS REP SHS A 44852D108 1,379 621,141 SH   SOLE 0 621,141 0 0
Halozyme Therapeutics COM 40637H109 30 763 SH   DFND 3 763 0 0
Harris Corp COM 502431109 13 61 SH   DFND 3 61 0 0
Hashicorp Inc COM CL A 418100103 68,037 2,113,613 SH   DFND 1 2,113,613 0 0
Hashicorp Inc COM CL A 418100103 89,706 2,786,779 SH   DFND 2 2,589,172 0 197,607
Hashicorp Inc COM CL A 418100103 7,162 222,487 SH   DFND 3 222,487 0 0
Hashicorp Inc COM CL A 418100103 14,735 457,756 SH   SOLE 0 457,756 0 0
Health Catalyst Inc COM 42225T107 669 69,008 SH   DFND 1 69,008 0 0
Health Catalyst Inc COM 42225T107 1,467 151,258 SH   DFND 2 151,258 0 0
Health Catalyst Inc COM 42225T107 1,801 185,687 SH   DFND 3 185,687 0 0
Healthcare Services Group Inc COM 421906108 2 157 SH   DFND 3 157 0 0
Heron Therapeutics Inc COM 427746102 1 308 SH   DFND 3 308 0 0
Hershey Foods Corporation COM 427866108 16,358 74,198 SH   DFND 2 74,198 0 0
Hershey Foods Corporation COM 427866108 4,581 20,779 SH   SOLE 0 20,779 0 0
Hillenbrand COM 431571108 6 170 SH   DFND 3 170 0 0
Howard Hughes COM 44267D107 21,028 379,630 SH   DFND 1 379,630 0 0
Howard Hughes COM 44267D107 66,296 1,196,898 SH   DFND 2 1,083,542 0 113,356
Howard Hughes COM 44267D107 13,469 243,160 SH   DFND 3 145,295 0 97,865
Howard Hughes COM 44267D107 61,816 1,116,009 SH   SOLE 0 731,221 0 384,788
Hubbell COM 443510607 19 87 SH   DFND 3 87 0 0
Hubspot Inc COM 443573100 34 126 SH   DFND 3 126 0 0
Humana COM 444859102 27 55 SH   DFND 3 55 0 0
Hutchison China Meditech SPONSORED ADR 44842L103 1,179 133,107 SH   DFND 1 133,107 0 0
Hutchison China Meditech SPONSORED ADR 44842L103 647 73,002 SH   DFND 2 365 0 72,637
Hutchison China Meditech SPONSORED ADR 44842L103 1,628 183,709 SH   DFND 3 120 0 183,589
ICICI Bank ADR ADR 45104G104 80,265 3,827,617 SH   DFND 1 3,827,617 0 0
ICICI Bank ADR ADR 45104G104 71,755 3,421,778 SH   DFND 2 3,421,778 0 0
ICICI Bank ADR ADR 45104G104 19,565 933,015 SH   DFND 3 634,325 0 298,690
ICICI Bank ADR ADR 45104G104 5,144 245,305 SH   DFND 4 245,305 0 0
IPG Photonics Corp COM 44980X109 10,185 120,747 SH   DFND 1 120,747 0 0
IPG Photonics Corp COM 44980X109 7,797 92,433 SH   DFND 2 36,467 0 55,966
IPG Photonics Corp COM 44980X109 3,872 45,906 SH   DFND 3 45,906 0 0
IPG Photonics Corp COM 44980X109 7,620 90,336 SH   SOLE 0 90,336 0 0
Iac/Interactivecorp COM 44891N208 11,198 202,209 SH   DFND 1 202,209 0 0
Iac/Interactivecorp COM 44891N208 34,446 621,985 SH   DFND 2 562,319 0 59,666
Iac/Interactivecorp COM 44891N208 7,291 131,660 SH   DFND 3 78,112 0 53,548
Iac/Interactivecorp COM 44891N208 33,725 608,972 SH   SOLE 0 402,044 0 206,928
Illumina COM 452327109 341,250 1,788,618 SH   DFND 1 1,788,618 0 0
Illumina COM 452327109 1,996,532 10,464,553 SH   DFND 2 7,704,941 0 2,759,612
Illumina COM 452327109 245,749 1,288,060 SH   DFND 3 998,686 0 289,374
Illumina COM 452327109 1,045,314 5,478,870 SH   SOLE 0 4,538,026 0 940,844
InMode SHS M5425M103 17 596 SH   DFND 3 596 0 0
Incyte Corp COM 45337C102 11 165 SH   DFND 3 165 0 0
Infinera COM 45667G103 14 2,941 SH   DFND 3 2,941 0 0
Infosys Ltd ADR SPONSORED ADR 456788108 19,736 1,163,019 SH   DFND 1 1,163,019 0 0
Infosys Ltd ADR SPONSORED ADR 456788108 14,899 877,941 SH   DFND 2 111,463 0 766,478
Infosys Ltd ADR SPONSORED ADR 456788108 22,903 1,349,619 SH   DFND 3 511,283 0 838,336
Infosys Ltd ADR SPONSORED ADR 456788108 3,042 179,269 SH   DFND 4 179,269 0 0
Inogen Inc COM 45780L104 3 141 SH   DFND 3 141 0 0
Insmed Inc COM 457669307 15 707 SH   DFND 3 707 0 0
Inspire Medical Systems COM 457730109 29 162 SH   DFND 3 162 0 0
Intercept Pharmaceuticals Inc COM 45845P108 1 101 SH   DFND 3 101 0 0
International Game Technology SHS G4863A108 16 1,024 SH   DFND 3 1,024 0 0
Intuit COM 461202103 20,282 52,366 SH   DFND 1 52,366 0 0
Intuit COM 461202103 166 428 SH   DFND 2 0 0 428
Intuit COM 461202103 3,029 7,820 SH   DFND 3 7,820 0 0
Intuit COM 461202103 11,740 30,310 SH   SOLE 0 30,310 0 0
Intuitive Surgical COM NEW 46120E602 65,350 348,644 SH   DFND 1 348,644 0 0
Intuitive Surgical COM NEW 46120E602 500,620 2,670,826 SH   DFND 2 1,134,099 0 1,536,727
Intuitive Surgical COM NEW 46120E602 72,957 389,229 SH   DFND 3 309,886 0 79,343
Intuitive Surgical COM NEW 46120E602 148,161 790,443 SH   SOLE 0 360,482 0 429,961
Invitae COM 46185L103 2 800 SH   DFND 3 800 0 0
Ionis Pharmaceuticals COM 462222100 2,473 55,905 SH   DFND 1 55,905 0 0
Ionis Pharmaceuticals COM 462222100 5,191 117,355 SH   DFND 2 117,355 0 0
Ionis Pharmaceuticals COM 462222100 6,704 151,582 SH   DFND 3 151,582 0 0
Itau Unibanco Holding SA-ADR SPON ADR REP PFD 465562106 12,532 2,424,033 SH   DFND 1 2,424,033 0 0
Itau Unibanco Holding SA-ADR SPON ADR REP PFD 465562106 35,593 6,884,504 SH   DFND 2 501,332 0 6,383,172
Itau Unibanco Holding SA-ADR SPON ADR REP PFD 465562106 48,107 9,304,961 SH   DFND 3 768,684 0 8,536,277
Itau Unibanco Holding SA-ADR SPON ADR REP PFD 465562106 1,992 385,212 SH   DFND 4 385,212 0 0
Ivanhoe Mines COM CL A 46579R104 9 1,400 SH   DFND 2 1,400 0 0
J&J Snack Foods Corp COM 466032109 11 83 SH   DFND 3 83 0 0
JFrog Ltd ORD SHS M6191J100 13,375 604,939 SH   DFND 1 604,939 0 0
JFrog Ltd ORD SHS M6191J100 7,971 360,500 SH   DFND 2 142,609 0 217,891
JFrog Ltd ORD SHS M6191J100 4,172 188,700 SH   DFND 3 188,700 0 0
JFrog Ltd ORD SHS M6191J100 9,155 414,081 SH   SOLE 0 414,081 0 0
Jack Henry & Associates COM 426281101 11 62 SH   DFND 3 62 0 0
Jazz Pharmaceuticals SHS G50871105 22 168 SH   DFND 3 168 0 0
Joby Aviation Inc COM G65163100 37 8,495 SH   DFND 1 8,495 0 0
Joby Aviation Inc COM G65163100 33,242 7,677,200 SH   SOLE 0 7,677,200 0 0
Johnson & Johnson COM 478160104 16 99 SH   DFND 3 99 0 0
Jumia Technologies Ag ADR SPONSORED ADS 48138M105 54,560 9,390,770 SH   DFND 2 8,709,322 0 681,448
Jumia Technologies Ag ADR SPONSORED ADS 48138M105 2,522 434,078 SH   DFND 3 374 0 433,704
KE Holdings ADR ADR 482497104 8,691 496,061 SH   DFND 1 496,061 0 0
KE Holdings ADR ADR 482497104 20,092 1,146,785 SH   DFND 2 603,046 0 543,739
KE Holdings ADR ADR 482497104 190 10,854 SH   DFND 3 10,854 0 0
KE Holdings ADR ADR 482497104 848 48,406 SH   SOLE 0 48,406 0 0
KFORCE INC. COM 493732101 17 295 SH   DFND 3 295 0 0
Knowles Corp COM 49926D109 15 1,200 SH   DFND 3 1,200 0 0
Kulicke & Soffa Industries Inc COM 501242101 19 491 SH   DFND 3 491 0 0
Lemonade Inc COM 52567D107 32,571 1,537,840 SH   DFND 1 1,537,840 0 0
Lemonade Inc COM 52567D107 50,120 2,366,375 SH   DFND 2 2,343,316 0 23,059
Lemonade Inc COM 52567D107 1,697 80,101 SH   DFND 3 80,101 0 0
Lemonade Inc COM 52567D107 20,099 948,966 SH   SOLE 0 948,966 0 0
LendingTree COM 52603B107 5,519 231,314 SH   DFND 1 231,314 0 0
LendingTree COM 52603B107 4,355 182,541 SH   DFND 2 71,773 0 110,768
LendingTree COM 52603B107 2,207 92,499 SH   DFND 3 86,666 0 5,833
LendingTree COM 52603B107 2,858 119,788 SH   SOLE 0 119,788 0 0
Li Auto ADR SPONS ADS 50202M102 17,057 741,294 SH   DFND 1 741,294 0 0
Li Auto ADR SPONS ADS 50202M102 52,414 2,277,890 SH   DFND 2 2,041,286 0 236,604
Li Auto ADR SPONS ADS 50202M102 11,317 491,809 SH   DFND 3 278,655 0 213,154
Li Auto ADR SPONS ADS 50202M102 53,250 2,314,193 SH   SOLE 0 1,499,121 0 815,072
Liberty Broadband Corp COM 530307305 5 70 SH   DFND 3 70 0 0
Lightspeed POS COM 53229C107 5 310 SH   DFND 3 310 0 0
Lilium N.V. CL A COM N52586109 23 10,039 SH   DFND 1 10,039 0 0
Lilium N.V. CL A COM N52586109 2,551 1,118,923 SH   DFND 2 1,118,923 0 0
Lilium N.V. CL A COM N52586109 40,355 17,699,615 SH   SOLE 0 17,699,615 0 0
Lincoln Electric Holdings Inc COM 533900106 11 91 SH   DFND 3 91 0 0
LivePerson Inc COM 538146101 4,042 429,091 SH   DFND 1 429,091 0 0
LivePerson Inc COM 538146101 2,890 306,771 SH   DFND 2 121,367 0 185,404
LivePerson Inc COM 538146101 1,263 134,070 SH   DFND 3 134,070 0 0
LivePerson Inc COM 538146101 2,335 247,880 SH   SOLE 0 247,880 0 0
Liveramp Holdings Inc COM 53815P108 11,176 615,401 SH   DFND 1 615,401 0 0
Liveramp Holdings Inc COM 53815P108 6,121 337,043 SH   DFND 2 131,895 0 205,148
Liveramp Holdings Inc COM 53815P108 3,225 177,588 SH   DFND 3 177,588 0 0
Liveramp Holdings Inc COM 53815P108 5,359 295,075 SH   SOLE 0 295,075 0 0
Logitech International SA SHS H50430232 11 235 SH   DFND 3 235 0 0
Lufax Holding Ltd COM 54975P102 17,716 6,974,611 SH   DFND 1 6,974,611 0 0
Lufax Holding Ltd COM 54975P102 46,025 18,119,910 SH   DFND 2 10,376,573 0 7,743,337
Lufax Holding Ltd COM 54975P102 430 169,320 SH   DFND 3 169,320 0 0
Lyell Immunopharma Inc COM 55083R104 934 127,358 SH   DFND 1 127,358 0 0
Lyell Immunopharma Inc COM 55083R104 2,042 278,636 SH   DFND 2 278,636 0 0
Lyell Immunopharma Inc COM 55083R104 2,559 349,111 SH   DFND 3 349,111 0 0
Lyft Inc Class A Common CL A COM 55087P104 16 1,228 SH   DFND 3 1,228 0 0
M&T Bank Corp COM 55261F104 4,357 24,709 SH   SOLE 0 24,709 0 0
MELI Kaszek Pioneer CL A COM G5S74L106 19,740 2,000,000 SH   DFND 2 2,000,000 0 0
MP Materials COM CL A 553368101 49,750 1,822,340 SH   DFND 1 1,822,340 0 0
MP Materials COM CL A 553368101 2,910 106,600 SH   DFND 3 106,600 0 0
MakeMyTrip SHS V5633W109 80,062 2,607,869 SH   DFND 2 1,950,571 0 657,298
Marathon Digital Holdings COM 565788106 2 200 SH   DFND 3 200 0 0
Markel Corp COM 570535104 47,956 44,231 SH   DFND 1 44,231 0 0
Markel Corp COM 570535104 160,995 148,489 SH   DFND 2 134,712 0 13,777
Markel Corp COM 570535104 31,692 29,230 SH   DFND 3 17,377 0 11,853
Markel Corp COM 570535104 154,548 142,543 SH   SOLE 0 95,904 0 46,639
MarketAxess Holdings COM 57060D108 106,778 479,923 SH   DFND 1 479,923 0 0
MarketAxess Holdings COM 57060D108 145,698 654,850 SH   DFND 2 547,494 0 107,356
MarketAxess Holdings COM 57060D108 21,275 95,624 SH   DFND 3 86,517 0 9,107
MarketAxess Holdings COM 57060D108 42,141 189,405 SH   SOLE 0 189,405 0 0
Marriott International CL A 571903202 14 100 SH   DFND 3 100 0 0
Martin Marietta Materials COM 573284106 149,102 462,921 SH   DFND 1 462,921 0 0
Martin Marietta Materials COM 573284106 517,590 1,606,974 SH   DFND 2 1,459,004 0 147,970
Martin Marietta Materials COM 573284106 89,260 277,129 SH   DFND 3 162,004 0 115,125
Martin Marietta Materials COM 573284106 340,922 1,058,468 SH   SOLE 0 760,839 0 297,629
Masimo Corp COM 574795100 2,281 16,161 SH   DFND 1 16,161 0 0
Masimo Corp COM 574795100 4,776 33,832 SH   DFND 2 33,832 0 0
Masimo Corp COM 574795100 6,160 43,641 SH   DFND 3 43,641 0 0
Mastercard Inc-Class A CL A 57636Q104 98,446 346,226 SH   DFND 1 346,226 0 0
Mastercard Inc-Class A CL A 57636Q104 326,499 1,148,268 SH   DFND 2 1,042,865 0 105,403
Mastercard Inc-Class A CL A 57636Q104 64,882 228,185 SH   DFND 3 135,886 0 92,299
Mastercard Inc-Class A CL A 57636Q104 299,535 1,053,441 SH   SOLE 0 683,136 0 370,305
Materialise Nv ADR SPONSORED ADS 57667T100 2,870 268,000 SH   DFND 2 268,000 0 0
Mativ Inc COM 808541106 6 265 SH   DFND 3 265 0 0
MaxCyte COM 57777K106 1,313 202,800 SH   DFND 1 202,800 0 0
Maxlinear Inc COM 57776J100 13 405 SH   DFND 3 405 0 0
McDonald's COM 580135101 16,947 73,448 SH   DFND 1 73,448 0 0
McDonald's COM 580135101 282 1,220 SH   DFND 2 0 0 1,220
McDonald's COM 580135101 700 3,034 SH   DFND 3 3,034 0 0
McDonald's COM 580135101 19,724 85,483 SH   SOLE 0 85,483 0 0
Medifast Inc COM 58470H101 13 121 SH   DFND 3 121 0 0
Medtronic COM G5960L103 20,198 250,124 SH   DFND 1 250,124 0 0
Medtronic COM G5960L103 171 2,120 SH   DFND 2 0 0 2,120
Medtronic COM G5960L103 2,925 36,223 SH   DFND 3 36,223 0 0
Medtronic COM G5960L103 11,513 142,579 SH   SOLE 0 142,579 0 0
MercadoLibre COM 58733R102 319,921 386,481 SH   DFND 1 386,481 0 0
MercadoLibre COM 58733R102 3,651,440 4,411,124 SH   DFND 2 3,518,175 0 892,949
MercadoLibre COM 58733R102 208,448 251,816 SH   DFND 3 189,987 0 61,829
MercadoLibre COM 58733R102 7,562 9,135 SH   DFND 4 9,135 0 0
MercadoLibre COM 58733R102 599,875 724,679 SH   SOLE 0 662,318 0 62,361
Merck COM 58933Y105 13 148 SH   DFND 3 148 0 0
Meta Platforms Inc CL A 30303M102 92,552 682,136 SH   DFND 1 682,136 0 0
Meta Platforms Inc CL A 30303M102 532,007 3,921,044 SH   DFND 2 2,154,228 0 1,766,816
Meta Platforms Inc CL A 30303M102 85,060 626,913 SH   DFND 3 458,836 0 168,077
Meta Platforms Inc CL A 30303M102 247,731 1,825,845 SH   SOLE 0 1,030,492 0 795,353
Mettler-Toledo COM 592688105 73,326 67,636 SH   DFND 1 67,636 0 0
Mettler-Toledo COM 592688105 309,463 285,451 SH   DFND 2 211,161 0 74,290
Mettler-Toledo COM 592688105 4,034 3,721 SH   DFND 3 2,502 0 1,219
Mettler-Toledo COM 592688105 27,717 25,566 SH   SOLE 0 25,566 0 0
Microsoft COM 594918104 223,301 958,783 SH   DFND 1 958,783 0 0
Microsoft COM 594918104 567,540 2,436,840 SH   DFND 2 2,229,599 0 207,241
Microsoft COM 594918104 116,697 501,059 SH   DFND 3 314,862 0 186,197
Microsoft COM 594918104 535,911 2,301,034 SH   SOLE 0 1,555,137 0 745,897
Mirati Therapeutics COM 60468T105 15 214 SH   DFND 3 214 0 0
Moderna Inc COM 60770K107 551,757 4,666,018 SH   DFND 1 4,666,018 0 0
Moderna Inc COM 60770K107 2,915,247 24,653,254 SH   DFND 2 19,621,009 0 5,032,245
Moderna Inc COM 60770K107 302,976 2,562,167 SH   DFND 3 2,008,508 0 553,659
Moderna Inc COM 60770K107 1,584,383 13,398,584 SH   SOLE 0 11,698,068 0 1,700,516
Momentive Global Inc COM 60878Y108 6 1,095 SH   DFND 3 1,095 0 0
MongoDB Inc COM 60937P106 42 213 SH   DFND 3 213 0 0
MongoDB Inc COM 60937P106 674 3,393 SH   SOLE 0 3,393 0 0
Monolithic Power Systems Inc COM 609839105 21 59 SH   DFND 3 59 0 0
Moody's Corp COM 615369105 140,231 576,822 SH   DFND 1 576,822 0 0
Moody's Corp COM 615369105 469,991 1,933,243 SH   DFND 2 1,757,845 0 175,398
Moody's Corp COM 615369105 94,192 387,445 SH   DFND 3 229,665 0 157,780
Moody's Corp COM 615369105 434,602 1,787,678 SH   SOLE 0 1,155,211 0 632,467
NIO Inc ADR SPON ADS 62914V106 41,342 2,621,582 SH   DFND 1 2,621,582 0 0
NIO Inc ADR SPON ADS 62914V106 991,652 62,882,169 SH   DFND 2 48,001,121 0 14,881,048
NIO Inc ADR SPON ADS 62914V106 45,951 2,913,844 SH   DFND 3 2,321,870 0 591,974
NIO Inc ADR SPON ADS 62914V106 447,294 28,363,583 SH   SOLE 0 25,144,374 0 3,219,209
NV5 Global COM 62945V109 19 155 SH   DFND 3 155 0 0
NVIDIA COM 67066G104 235,055 1,936,359 SH   DFND 1 1,936,359 0 0
NVIDIA COM 67066G104 1,023,330 8,430,103 SH   DFND 2 4,539,309 0 3,890,794
NVIDIA COM 67066G104 123,838 1,020,168 SH   DFND 3 815,602 0 204,566
NVIDIA COM 67066G104 472,469 3,892,154 SH   SOLE 0 2,879,850 0 1,012,304
Nano Dimension ADR SPONS ADS 63008G203 4 1,600 SH   DFND 3 1,600 0 0
Nanobiotix ADR COM 63009J107 2,986 850,841 SH   DFND 1 850,841 0 0
Nanobiotix ADR COM 63009J107 1,928 549,159 SH   SOLE 0 549,159 0 0
National Instruments Corp COM 636518102 33,119 877,549 SH   DFND 1 877,549 0 0
National Instruments Corp COM 636518102 261 6,924 SH   DFND 2 0 0 6,924
National Instruments Corp COM 636518102 5,011 132,783 SH   DFND 3 132,783 0 0
National Instruments Corp COM 636518102 18,188 481,925 SH   SOLE 0 481,925 0 0
Nektar Therapeutics COM 640268108 4 1,376 SH   DFND 3 1,376 0 0
NetEase.com ADR SPONSORED ADR 64110W102 7,813 103,340 SH   DFND 2 0 0 103,340
Netflix Inc COM 64110L106 248,745 1,056,510 SH   DFND 1 1,056,510 0 0
Netflix Inc COM 64110L106 837,008 3,555,081 SH   DFND 2 2,160,703 0 1,394,378
Netflix Inc COM 64110L106 106,639 452,935 SH   DFND 3 350,769 0 102,166
Netflix Inc COM 64110L106 448,040 1,902,992 SH   SOLE 0 1,423,969 0 479,023
Nevro Corp COM 64157F103 7 154 SH   DFND 3 154 0 0
New Relic COM 64829B100 42 733 SH   DFND 3 733 0 0
Newmont Mining COM 651639106 1,091 25,959 SH   DFND 1 25,959 0 0
NextEra Energy COM 65339F101 17,739 226,230 SH   DFND 1 226,230 0 0
NextEra Energy COM 65339F101 1,011 12,895 SH   DFND 3 12,895 0 0
Nike COM 654106103 7 90 SH   DFND 3 90 0 0
Novanta Inc COM 67000B104 71 616 SH   DFND 2 616 0 0
Novanta Inc COM 67000B104 847 7,322 SH   DFND 3 7,322 0 0
Novavax Inc COM NEW 670002401 2 130 SH   DFND 3 130 0 0
Novocure Ltd ORD SHS G6674U108 186,730 2,457,618 SH   DFND 1 2,457,618 0 0
Novocure Ltd ORD SHS G6674U108 296,765 3,905,828 SH   DFND 2 3,516,256 0 389,572
Novocure Ltd ORD SHS G6674U108 46,851 616,625 SH   DFND 3 507,201 0 109,424
Novocure Ltd ORD SHS G6674U108 146,954 1,934,120 SH   SOLE 0 1,503,031 0 431,089
Nu Holdings Ltd. ORD SHS CL A G6683N103 28,040 6,372,830 SH   DFND 1 6,372,830 0 0
Nu Holdings Ltd. ORD SHS CL A G6683N103 320,983 72,950,673 SH   DFND 2 62,970,052 0 9,980,621
Nu Holdings Ltd. ORD SHS CL A G6683N103 27,965 6,355,749 SH   DFND 3 4,947,099 0 1,408,650
Nu Holdings Ltd. ORD SHS CL A G6683N103 6,845 1,555,766 SH   SOLE 0 582,989 0 972,777
Nucana Plc ADR SPONSORED ADR 67022C106 2,529 2,420,041 SH   DFND 1 2,420,041 0 0
Nucana Plc ADR SPONSORED ADR 67022C106 1,295 1,238,989 SH   SOLE 0 1,238,989 0 0
Nutanix Inc COM 67059N108 12 563 SH   DFND 3 563 0 0
Oatly Inc. SPONS ADS 67421J108 96,996 36,880,496 SH   DFND 2 30,644,905 0 6,235,591
Oatly Inc. SPONS ADS 67421J108 2,057 782,153 SH   SOLE 0 782,153 0 0
On Semiconductor Corp COM 682189105 34 548 SH   DFND 3 548 0 0
Opko Health Inc COM 68375N103 13 6,635 SH   DFND 3 6,635 0 0
Oscar Health Inc COM 687793109 12,908 2,586,787 SH   DFND 1 2,586,787 0 0
Oscar Health Inc COM 687793109 39,239 7,863,543 SH   DFND 2 7,122,673 0 740,870
Oscar Health Inc COM 687793109 8,690 1,741,580 SH   DFND 3 1,072,841 0 668,739
Oscar Health Inc COM 687793109 40,801 8,176,578 SH   SOLE 0 5,589,753 0 2,586,825
Outset Medical COM 690145107 5 306 SH   DFND 3 306 0 0
Oxford Industries Inc COM 691497309 5 55 SH   DFND 3 55 0 0
Ozon Holdings ADR COM 69269L104 0 333,970 SH   DFND 1 333,970 0 0
Ozon Holdings ADR COM 69269L104 0 2,478,153 SH   DFND 2 1,319,308 0 1,158,845
Ozon Holdings ADR COM 69269L104 0 19,278 SH   DFND 3 19,278 0 0
PROCEPT BioRobotics COM 74276L105 16 376 SH   DFND 3 376 0 0
Pacira BioSciences COM 695127100 37,868 711,933 SH   DFND 1 711,933 0 0
Pacira BioSciences COM 695127100 26,966 506,979 SH   DFND 2 201,975 0 305,004
Pacira BioSciences COM 695127100 15,364 288,846 SH   DFND 3 244,659 0 44,187
Pacira BioSciences COM 695127100 18,087 340,039 SH   SOLE 0 340,039 0 0
PagerDuty COM 69553P100 13 565 SH   DFND 3 565 0 0
Paychex COM 704326107 13 116 SH   DFND 3 116 0 0
Peloton Interactive Inc CL A COM 70614W100 26,688 3,851,056 SH   DFND 1 3,851,056 0 0
Peloton Interactive Inc CL A COM 70614W100 101,854 14,697,547 SH   DFND 2 7,436,242 0 7,261,305
Peloton Interactive Inc CL A COM 70614W100 17,828 2,572,529 SH   DFND 3 2,035,133 0 537,396
Peloton Interactive Inc CL A COM 70614W100 27,706 3,998,009 SH   SOLE 0 1,921,099 0 2,076,910
Penumbra Inc COM 70975L107 88,959 469,192 SH   DFND 1 469,192 0 0
Penumbra Inc COM 70975L107 126,344 666,371 SH   DFND 2 659,832 0 6,539
Penumbra Inc COM 70975L107 4,597 24,248 SH   DFND 3 24,248 0 0
Penumbra Inc COM 70975L107 19,306 101,827 SH   SOLE 0 101,827 0 0
Pepsico COM 713448108 62,275 381,448 SH   DFND 1 381,448 0 0
Pepsico COM 713448108 490 3,004 SH   DFND 2 0 0 3,004
Pepsico COM 713448108 9,536 58,412 SH   DFND 3 58,412 0 0
Pepsico COM 713448108 33,974 208,099 SH   SOLE 0 208,099 0 0
Petrobras Common ADR SPONSORED ADR 71654V408 164,976 13,369,169 SH   DFND 1 13,369,169 0 0
Petrobras Common ADR SPONSORED ADR 71654V408 544,739 44,144,187 SH   DFND 2 22,442,562 0 21,701,625
Petrobras Common ADR SPONSORED ADR 71654V408 32,498 2,633,541 SH   DFND 3 1,734,745 0 898,796
Petrobras Common ADR SPONSORED ADR 71654V408 9,132 740,063 SH   DFND 4 740,063 0 0
Petrobras Common ADR SPONSORED ADR 71654V408 9,129 739,803 SH   SOLE 0 739,803 0 0
Petrobras Pref ADR SP ADR NON VTG 71654V101 15,204 1,372,181 SH   DFND 1 1,372,181 0 0
Petrobras Pref ADR SP ADR NON VTG 71654V101 97,813 8,827,871 SH   DFND 2 6,585,156 0 2,242,715
Petrobras Pref ADR SP ADR NON VTG 71654V101 851 76,793 SH   DFND 3 76,793 0 0
Pfizer COM 717081103 20 466 SH   DFND 3 466 0 0
Piedmont Lithium Inc COM 72016P105 11 212 SH   DFND 3 212 0 0
Pinduoduo Inc ADR SPONSORED ADS 722304102 106,742 1,705,684 SH   DFND 1 1,705,684 0 0
Pinduoduo Inc ADR SPONSORED ADS 722304102 1,024,674 16,373,818 SH   DFND 2 8,955,979 0 7,417,839
Pinduoduo Inc ADR SPONSORED ADS 722304102 114,490 1,829,495 SH   DFND 3 1,465,151 0 364,344
Pinduoduo Inc ADR SPONSORED ADS 722304102 519,529 8,301,844 SH   SOLE 0 6,322,694 0 1,979,150
Pinterest COM 72352L106 51,075 2,192,050 SH   DFND 1 2,192,050 0 0
Pinterest COM 72352L106 79,656 3,418,731 SH   DFND 2 3,386,325 0 32,406
Pinterest COM 72352L106 2,708 116,225 SH   DFND 3 116,225 0 0
Pinterest COM 72352L106 11,966 513,565 SH   SOLE 0 513,565 0 0
Precision BioSciences Inc COM 74019P108 6 4,774 SH   DFND 2 4,774 0 0
Precision BioSciences Inc COM 74019P108 74 56,678 SH   DFND 3 56,678 0 0
Procter & Gamble COM 742718109 62,196 492,643 SH   DFND 1 492,643 0 0
Procter & Gamble COM 742718109 490 3,881 SH   DFND 2 0 0 3,881
Procter & Gamble COM 742718109 9,563 75,750 SH   DFND 3 75,750 0 0
Procter & Gamble COM 742718109 33,834 267,995 SH   SOLE 0 267,995 0 0
Progressive COM 743315103 3,922 33,746 SH   SOLE 0 33,746 0 0
Progyny COM 74340E103 22,747 613,797 SH   DFND 1 613,797 0 0
Progyny COM 74340E103 17,490 471,926 SH   DFND 2 186,723 0 285,203
Progyny COM 74340E103 9,269 250,105 SH   DFND 3 220,441 0 29,664
Progyny COM 74340E103 8,572 231,309 SH   SOLE 0 231,309 0 0
Prologis Inc REIT COM 74340W103 28,480 280,314 SH   DFND 1 280,314 0 0
Prologis Inc REIT COM 74340W103 3,272 32,205 SH   DFND 3 32,205 0 0
Proterra Inc COM 74374T109 60 12,101 SH   DFND 1 12,101 0 0
Ptc Therapeutics Inc COM 69366J200 12 246 SH   DFND 3 246 0 0
Pure Storage Inc COM 74624M102 37 1,335 SH   DFND 3 1,335 0 0
Q2 Holdings Inc COM 74736L109 7,724 239,881 SH   DFND 1 239,881 0 0
Q2 Holdings Inc COM 74736L109 5,010 155,584 SH   DFND 2 62,429 0 93,155
Q2 Holdings Inc COM 74736L109 2,701 83,886 SH   DFND 3 83,886 0 0
Q2 Holdings Inc COM 74736L109 3,936 122,235 SH   SOLE 0 122,235 0 0
Qualcomm COM 747525103 21 183 SH   DFND 3 183 0 0
Quanterix Corp COM 74766Q101 4,310 391,135 SH   DFND 1 391,135 0 0
Quanterix Corp COM 74766Q101 26 2,370 SH   DFND 2 2,370 0 0
Quanterix Corp COM 74766Q101 320 29,013 SH   DFND 3 29,013 0 0
Quanterix Corp COM 74766Q101 2,311 209,677 SH   SOLE 0 209,677 0 0
QuantumScape Corp COM CL A 74767V109 2,936 349,062 SH   DFND 1 349,062 0 0
QuantumScape Corp COM CL A 74767V109 7,681 913,279 SH   SOLE 0 913,279 0 0
Quest Diagnostics COM 74834L100 18 145 SH   DFND 3 145 0 0
Quidel Corp COM 219798105 9 128 SH   DFND 3 128 0 0
REGENXBIO COM 75901B107 20 752 SH   DFND 3 752 0 0
Rambus Inc COM 750917106 16 630 SH   DFND 3 630 0 0
Recursion Pharmaceuticals Inc CL A 75629V104 28,262 2,656,213 SH   DFND 1 2,656,213 0 0
Recursion Pharmaceuticals Inc CL A 75629V104 40,985 3,852,017 SH   DFND 2 3,815,952 0 36,065
Recursion Pharmaceuticals Inc CL A 75629V104 5,435 510,787 SH   DFND 3 510,787 0 0
Recursion Pharmaceuticals Inc CL A 75629V104 155,085 14,575,676 SH   SOLE 0 14,575,676 0 0
Redfin COM 75737F108 22,254 3,810,568 SH   DFND 1 3,810,568 0 0
Redfin COM 75737F108 29,918 5,123,008 SH   DFND 2 4,985,904 0 137,104
Redfin COM 75737F108 1,786 305,852 SH   DFND 3 264,255 0 41,597
Redfin COM 75737F108 4,213 721,353 SH   SOLE 0 721,353 0 0
Regeneron Pharmaceuticals COM 75886F107 32 47 SH   DFND 3 47 0 0
Relay Therapeutics Inc COM 75943R102 1,544 69,032 SH   DFND 1 69,032 0 0
Relay Therapeutics Inc COM 75943R102 3,357 150,050 SH   DFND 2 150,050 0 0
Relay Therapeutics Inc COM 75943R102 4,150 185,538 SH   DFND 3 185,538 0 0
ResMed COM 761152107 2,824 12,935 SH   DFND 1 12,935 0 0
ResMed COM 761152107 6,025 27,599 SH   DFND 2 27,599 0 0
ResMed COM 761152107 7,651 35,047 SH   DFND 3 35,047 0 0
Research in Motion COM 09228F103 11 2,434 SH   DFND 3 2,434 0 0
Rexford Industrial Realty REIT COM 76169C100 36,723 706,204 SH   DFND 1 706,204 0 0
Rexford Industrial Realty REIT COM 76169C100 4,555 87,598 SH   DFND 3 87,598 0 0
Rio Tinto Spn.Adr 1:1 SPONSORED ADR 767204100 3 60 SH   DFND 4 60 0 0
Ritchie Bros Auctioneers (USA) COM 767744105 99,075 1,585,711 SH   DFND 2 1,443,740 0 141,971
Ritchie Bros Auctioneers (USA) COM 767744105 2 35 SH   DFND 4 35 0 0
Ritchie Bros. Auctioneers COM 767744105 74,129 1,180,123 SH   DFND 2 710,447 0 469,676
Rivian Automotive Inc COM CL A 76954A103 39,663 1,205,195 SH   DFND 1 1,205,195 0 0
Rivian Automotive Inc COM CL A 76954A103 59,318 1,802,443 SH   DFND 2 1,784,824 0 17,619
Rivian Automotive Inc COM CL A 76954A103 2,065 62,751 SH   DFND 3 62,751 0 0
Rivian Automotive Inc COM CL A 76954A103 9,580 291,104 SH   SOLE 0 291,104 0 0
Robert Half International Inc COM 770323103 10 131 SH   DFND 3 131 0 0
Roblox CL A 771049103 113,332 3,162,174 SH   DFND 1 3,162,174 0 0
Roblox CL A 771049103 399,494 11,146,604 SH   DFND 2 6,600,711 0 4,545,893
Roblox CL A 771049103 44,955 1,254,314 SH   DFND 3 1,021,757 0 232,557
Roblox CL A 771049103 191,525 5,343,897 SH   SOLE 0 4,083,502 0 1,260,395
Roku COM CL A 77543R102 69,806 1,237,701 SH   DFND 1 1,237,701 0 0
Roku COM CL A 77543R102 103,400 1,833,341 SH   DFND 2 1,815,348 0 17,993
Roku COM CL A 77543R102 3,601 63,844 SH   DFND 3 63,844 0 0
Roku COM CL A 77543R102 15,382 272,723 SH   SOLE 0 272,723 0 0
Rollins Inc COM 775711104 19 562 SH   DFND 3 562 0 0
Royalty Pharma SHS CLASS A G7709Q104 88,056 2,191,532 SH   DFND 1 2,191,532 0 0
Royalty Pharma SHS CLASS A G7709Q104 296,267 7,373,489 SH   DFND 2 6,696,581 0 676,908
Royalty Pharma SHS CLASS A G7709Q104 58,603 1,458,518 SH   DFND 3 861,766 0 596,752
Royalty Pharma SHS CLASS A G7709Q104 275,017 6,844,636 SH   SOLE 0 4,554,021 0 2,290,615
Rubius Therapeutics Inc COM 78116T103 385 887,000 SH   DFND 1 887,000 0 0
Rubius Therapeutics Inc COM 78116T103 99 228,492 SH   DFND 2 80,537 0 147,955
Rubius Therapeutics Inc COM 78116T103 66 152,722 SH   DFND 3 152,722 0 0
Rubius Therapeutics Inc COM 78116T103 1,555 3,585,559 SH   SOLE 0 3,585,559 0 0
Ryanair ADR SPONSORED ADR NE 783513203 17,101 292,730 SH   DFND 1 292,730 0 0
Ryanair ADR SPONSORED ADR NE 783513203 528,481 9,046,241 SH   DFND 2 7,867,863 0 1,178,378
Ryanair ADR SPONSORED ADR NE 783513203 6,271 107,343 SH   DFND 3 107,343 0 0
Ryanair ADR SPONSORED ADR NE 783513203 4 60 SH   DFND 4 60 0 0
Ryanair ADR SPONSORED ADR NE 783513203 7,067 120,961 SH   SOLE 0 113,715 0 7,246
S&P Global Inc COM 78409V104 61,796 202,379 SH   DFND 1 202,379 0 0
S&P Global Inc COM 78409V104 208,654 683,328 SH   DFND 2 622,059 0 61,269
S&P Global Inc COM 78409V104 40,292 131,953 SH   DFND 3 77,576 0 54,377
S&P Global Inc COM 78409V104 192,252 629,612 SH   SOLE 0 411,998 0 217,614
SCP Pool Corporation COM 73278L105 22 70 SH   DFND 3 70 0 0
SEA Ltd ADR ADR 81141R100 133,311 2,378,423 SH   DFND 1 2,378,423 0 0
SEA Ltd ADR ADR 81141R100 594,782 10,611,635 SH   DFND 2 8,018,978 0 2,592,657
SEA Ltd ADR ADR 81141R100 45,168 805,845 SH   DFND 3 547,895 0 257,950
SEA Ltd ADR ADR 81141R100 816 14,563 SH   DFND 4 14,563 0 0
SEA Ltd ADR ADR 81141R100 162,971 2,907,595 SH   SOLE 0 1,853,815 0 1,053,780
SKYWORKS SOLUTIONS, INC. COM 83088M102 12 136 SH   DFND 3 136 0 0
Sage Therapeutics Inc COM 78667J108 606 15,465 SH   DFND 1 15,465 0 0
Sage Therapeutics Inc COM 78667J108 1,330 33,958 SH   DFND 2 33,958 0 0
Sage Therapeutics Inc COM 78667J108 1,644 41,972 SH   DFND 3 41,972 0 0
Salesforce.com COM 79466L302 38,909 270,504 SH   DFND 1 270,504 0 0
Salesforce.com COM 79466L302 302,573 2,103,541 SH   DFND 2 908,685 0 1,194,856
Salesforce.com COM 79466L302 44,304 308,010 SH   DFND 3 246,287 0 61,723
Salesforce.com COM 79466L302 87,922 611,250 SH   SOLE 0 277,869 0 333,381
Sana Biotechnology Inc COM 799566104 10,943 1,823,899 SH   DFND 1 1,823,899 0 0
Sana Biotechnology Inc COM 799566104 16,584 2,763,972 SH   DFND 2 2,763,972 0 0
Sana Biotechnology Inc COM 799566104 1,026 170,970 SH   DFND 3 170,970 0 0
Sana Biotechnology Inc COM 799566104 37,247 6,207,895 SH   SOLE 0 6,207,895 0 0
Sangamo Biosciences COM 800677106 12 2,510 SH   DFND 3 2,510 0 0
Sarepta Therapeutics Inc COM 803607100 22 199 SH   DFND 3 199 0 0
Schrodinger COM 80810D103 8,308 332,569 SH   DFND 1 332,569 0 0
Schrodinger COM 80810D103 8,873 355,201 SH   DFND 2 139,779 0 215,422
Schrodinger COM 80810D103 4,326 173,197 SH   DFND 3 173,197 0 0
Schrodinger COM 80810D103 8,015 320,840 SH   SOLE 0 320,840 0 0
Seagen Inc COM 81181C104 18 128 SH   DFND 3 128 0 0
Seer COM CL A 81578P106 2 223 SH   DFND 3 223 0 0
Sei Investments Co COM 784117103 20 409 SH   DFND 3 409 0 0
Service Corp.Intl. COM 817565104 123,020 2,130,581 SH   DFND 1 2,130,581 0 0
Service Corp.Intl. COM 817565104 422,823 7,322,883 SH   DFND 2 6,665,097 0 657,786
Service Corp.Intl. COM 817565104 81,547 1,412,312 SH   DFND 3 834,103 0 578,209
Service Corp.Intl. COM 817565104 377,053 6,530,187 SH   SOLE 0 4,321,557 0 2,208,630
Sherwin-Williams Co COM 824348106 9,102 44,453 SH   DFND 2 44,453 0 0
ShockWave Medical Inc COM 82489T104 20,576 73,996 SH   DFND 1 73,996 0 0
ShockWave Medical Inc COM 82489T104 43,708 157,184 SH   DFND 2 104,698 0 52,486
ShockWave Medical Inc COM 82489T104 30,499 109,680 SH   DFND 3 109,680 0 0
ShockWave Medical Inc COM 82489T104 14,900 53,584 SH   SOLE 0 53,584 0 0
Shopify 'A' CL A 82509L107 314,124 11,660,125 SH   DFND 1 11,660,125 0 0
Shopify 'A' CL A 82509L107 986,818 36,630,225 SH   DFND 2 25,368,870 0 11,261,355
Shopify 'A' CL A 82509L107 111,833 4,151,184 SH   DFND 3 3,208,496 0 942,688
Shopify 'A' CL A 82509L107 1 42 SH   DFND 4 42 0 0
Shopify 'A' CL A 82509L107 321,789 11,944,650 SH   SOLE 0 8,538,966 0 3,405,684
Shopify Inc COM 82509L107 3,326 122,868 SH   DFND 2 122,868 0 0
Shopify Inc COM 82509L107 53 1,955 SH   DFND 3 1,955 0 0
Signature Bank COM 82669G104 5,503 36,446 SH   DFND 2 36,446 0 0
Signature Bank COM 82669G104 1,510 10,002 SH   SOLE 0 10,002 0 0
Silicon Motion Technology ADR COM 82706C108 16,617 254,907 SH   DFND 1 254,907 0 0
Silicon Motion Technology ADR COM 82706C108 145 2,221 SH   DFND 2 0 0 2,221
Silicon Motion Technology ADR COM 82706C108 2,325 35,672 SH   DFND 3 35,672 0 0
Silicon Motion Technology ADR COM 82706C108 9,350 143,428 SH   SOLE 0 143,428 0 0
Silk Road Medical COM 82710M100 11 235 SH   DFND 3 235 0 0
SiteOne Landscape Supply COM 82982L103 33,966 326,154 SH   DFND 1 326,154 0 0
SiteOne Landscape Supply COM 82982L103 109,700 1,053,392 SH   DFND 2 953,844 0 99,548
SiteOne Landscape Supply COM 82982L103 22,823 219,161 SH   DFND 3 130,356 0 88,805
SiteOne Landscape Supply COM 82982L103 105,623 1,014,244 SH   SOLE 0 665,875 0 348,369
Sixth Street Specialty Lending COM 83012A109 1,299 79,500 SH   DFND 1 79,500 0 0
Smartsheet COM 83200N103 12 352 SH   DFND 3 352 0 0
Snap Inc CL A 83304A106 38,950 3,966,417 SH   DFND 1 3,966,417 0 0
Snap Inc CL A 83304A106 57,975 5,903,800 SH   DFND 2 5,845,923 0 57,877
Snap Inc CL A 83304A106 2,043 208,034 SH   DFND 3 208,034 0 0
Snap Inc CL A 83304A106 10,955 1,115,601 SH   SOLE 0 1,115,601 0 0
Snap On COM 833034101 17 86 SH   DFND 3 86 0 0
Snowflake Inc COM 833445109 148,215 872,058 SH   DFND 1 872,058 0 0
Snowflake Inc COM 833445109 280,134 1,648,237 SH   DFND 2 1,584,203 0 64,034
Snowflake Inc COM 833445109 26,607 156,550 SH   DFND 3 107,116 0 49,434
Snowflake Inc COM 833445109 340,661 2,004,358 SH   SOLE 0 1,808,855 0 195,503
Solaredge Technologies Inc COM 83417M104 281 1,214 SH   DFND 1 1,214 0 0
Solaredge Technologies Inc COM 83417M104 39 167 SH   DFND 3 167 0 0
Sorrento Therapeutics COM 83587F202 6 3,711 SH   DFND 3 3,711 0 0
Spire Global Inc COM CL A 848560108 935 866,045 SH   SOLE 0 866,045 0 0
Splunk Inc COM 848637104 5,605 74,540 SH   DFND 1 74,540 0 0
Splunk Inc COM 848637104 8,512 113,190 SH   DFND 2 44,092 0 69,098
Splunk Inc COM 848637104 3,684 48,985 SH   DFND 3 48,985 0 0
Splunk Inc COM 848637104 5,556 73,884 SH   SOLE 0 73,884 0 0
Spotify Technology SA SHS L8681T102 105,919 1,227,339 SH   DFND 1 1,227,339 0 0
Spotify Technology SA SHS L8681T102 1,942,658 22,510,517 SH   DFND 2 17,082,329 0 5,428,188
Spotify Technology SA SHS L8681T102 64,027 741,914 SH   DFND 3 568,251 0 173,663
Spotify Technology SA SHS L8681T102 1 13 SH   DFND 4 13 0 0
Spotify Technology SA SHS L8681T102 300,733 3,484,734 SH   SOLE 0 2,690,102 0 794,632
Sprout Social COM 85209W109 19,483 321,078 SH   DFND 1 321,078 0 0
Sprout Social COM 85209W109 15,616 257,352 SH   DFND 2 100,802 0 156,550
Sprout Social COM 85209W109 8,001 131,856 SH   DFND 3 131,856 0 0
Sprout Social COM 85209W109 14,919 245,870 SH   SOLE 0 245,870 0 0
Staar Surgical COM PAR $0.01 852312305 103,231 1,463,237 SH   DFND 1 1,463,237 0 0
Staar Surgical COM PAR $0.01 852312305 115,469 1,636,702 SH   DFND 2 1,151,373 0 485,329
Staar Surgical COM PAR $0.01 852312305 37,716 534,602 SH   DFND 3 419,281 0 115,321
Staar Surgical COM PAR $0.01 852312305 105,350 1,493,262 SH   SOLE 0 1,162,392 0 330,870
Starbucks Corp COM 855244109 24,283 288,190 SH   DFND 1 288,190 0 0
Starbucks Corp COM 855244109 15,733 186,714 SH   DFND 2 175,977 0 10,737
Starbucks Corp COM 855244109 4,447 52,782 SH   DFND 3 49,282 0 3,500
Starbucks Corp COM 855244109 15,899 188,689 SH   SOLE 0 188,689 0 0
Stitch Fix COM CL A 860897107 11 2,755 SH   DFND 2 2,755 0 0
Stitch Fix COM CL A 860897107 128 32,301 SH   DFND 3 32,301 0 0
StoneCo COM CL A G85158106 1,529 160,397 SH   DFND 1 160,397 0 0
StoneCo COM CL A G85158106 12,136 1,273,498 SH   DFND 2 688,205 0 585,293
StoneCo COM CL A G85158106 87 9,131 SH   DFND 3 9,131 0 0
Stratasys SHS M85548101 3,261 226,300 SH   DFND 1 226,300 0 0
Stratasys SHS M85548101 4,193 291,008 SH   DFND 2 109,721 0 181,287
Stratasys SHS M85548101 2,075 143,996 SH   DFND 3 143,996 0 0
Stratasys SHS M85548101 2,084 144,600 SH   SOLE 0 144,600 0 0
Stryker COM 863667101 10 47 SH   DFND 3 47 0 0
Sumo Logic COM 86646P103 5 726 SH   DFND 3 726 0 0
Sunpower Corp COM 867652406 28 1,210 SH   DFND 3 1,210 0 0
Sutro Biopharma COM 869367102 5,785 1,042,428 SH   DFND 1 1,042,428 0 0
Sutro Biopharma COM 869367102 33 5,929 SH   DFND 2 5,929 0 0
Sutro Biopharma COM 869367102 386 69,532 SH   DFND 3 69,532 0 0
Sutro Biopharma COM 869367102 4,167 750,726 SH   SOLE 0 750,726 0 0
Sweetgreen COM CL A 87043Q108 14,678 793,421 SH   DFND 1 793,421 0 0
Sweetgreen COM CL A 87043Q108 21,079 1,139,410 SH   DFND 2 1,128,334 0 11,076
Sweetgreen COM CL A 87043Q108 745 40,284 SH   DFND 3 40,284 0 0
Sweetgreen COM CL A 87043Q108 3,284 177,529 SH   SOLE 0 177,529 0 0
T. Rowe Price COM 74144T108 17,534 166,977 SH   DFND 1 166,977 0 0
T. Rowe Price COM 74144T108 139 1,324 SH   DFND 2 0 0 1,324
T. Rowe Price COM 74144T108 2,690 25,613 SH   DFND 3 25,613 0 0
T. Rowe Price COM 74144T108 9,459 90,076 SH   SOLE 0 90,076 0 0
TJX Companies COM 872540109 6,674 107,431 SH   DFND 2 107,431 0 0
TJX Companies COM 872540109 4,335 69,779 SH   SOLE 0 69,779 0 0
TSMC ADR SPONSORED ADR 874039100 473,052 6,899,823 SH   DFND 2 5,322,073 0 1,577,750
TSMC ADR SPONSORED ADR 874039100 664 9,687 SH   DFND 3 9,687 0 0
TSMC ADR SPONSORED ADR 874039100 5 79 SH   DFND 4 79 0 0
TSMC ADR SPONSORED ADR 874039100 49,863 727,295 SH   SOLE 0 601,531 0 125,764
Tabula Rasa HealthCare Inc COM 873379101 2,694 561,175 SH   DFND 1 561,175 0 0
Tabula Rasa HealthCare Inc COM 873379101 12 2,495 SH   DFND 2 2,495 0 0
Tabula Rasa HealthCare Inc COM 873379101 141 29,449 SH   DFND 3 29,449 0 0
Tabula Rasa HealthCare Inc COM 873379101 1,145 238,574 SH   SOLE 0 238,574 0 0
Tandem Diabetes Care COM NEW 875372203 4,931 103,043 SH   DFND 1 103,043 0 0
Tandem Diabetes Care COM NEW 875372203 43 892 SH   DFND 2 892 0 0
Tandem Diabetes Care COM NEW 875372203 515 10,772 SH   DFND 3 10,772 0 0
Tandem Diabetes Care COM NEW 875372203 7,100 148,377 SH   SOLE 0 148,377 0 0
Target Corp COM 87612E106 14 97 SH   DFND 3 97 0 0
Tata Motors Ltd ADR COM 876568502 52,572 2,167,012 SH   DFND 1 2,167,012 0 0
Tata Motors Ltd ADR COM 876568502 27,040 1,114,586 SH   DFND 2 1,114,586 0 0
Tata Motors Ltd ADR COM 876568502 838 34,556 SH   DFND 3 34,556 0 0
Tata Motors Ltd ADR COM 876568502 13,690 564,300 SH   SOLE 0 564,300 0 0
Teladoc COM 87918A105 49,233 1,942,136 SH   DFND 1 1,942,136 0 0
Teladoc COM 87918A105 34,922 1,377,577 SH   DFND 2 917,562 0 460,015
Teladoc COM 87918A105 33,566 1,324,112 SH   DFND 3 1,097,720 0 226,392
Teladoc COM 87918A105 15,240 601,175 SH   SOLE 0 449,031 0 152,144
Telus Corp COM 87971M103 8 397 SH   DFND 3 397 0 0
Tenable Holdings COM 88025T102 11 315 SH   DFND 3 315 0 0
Tencent ADR SPON ADR 88032Q109 3 98 SH   DFND 4 98 0 0
Tencent Music Entertainment ADR SPONSORED ADS 88034P109 6,519 1,605,564 SH   DFND 1 1,605,564 0 0
Tencent Music Entertainment ADR SPONSORED ADS 88034P109 120,769 29,746,180 SH   DFND 2 20,849,928 0 8,896,252
Tencent Music Entertainment ADR SPONSORED ADS 88034P109 235 57,907 SH   DFND 3 57,907 0 0
Tencent Music Entertainment ADR SPONSORED ADS 88034P109 1 252 SH   DFND 4 252 0 0
Teradyne COM 880770102 54,494 725,131 SH   DFND 1 725,131 0 0
Teradyne COM 880770102 172,456 2,294,830 SH   DFND 2 2,077,881 0 216,949
Teradyne COM 880770102 35,506 472,471 SH   DFND 3 282,677 0 189,794
Teradyne COM 880770102 162,960 2,168,466 SH   SOLE 0 1,402,462 0 766,004
Tesla Inc COM 88160R101 879,456 3,315,573 SH   DFND 1 3,315,573 0 0
Tesla Inc COM 88160R101 4,130,300 15,571,348 SH   DFND 2 11,629,640 0 3,941,708
Tesla Inc COM 88160R101 428,505 1,615,477 SH   DFND 3 1,248,234 0 367,243
Tesla Inc COM 88160R101 1,956,069 7,374,435 SH   SOLE 0 5,983,096 0 1,391,339
Texas Instruments COM 882508104 3,724 24,059 SH   SOLE 0 24,059 0 0
Texas Roadhouse Inc COM 882681109 11 131 SH   DFND 3 131 0 0
The Trade Desk COM CL A 88339J105 562,553 9,415,118 SH   DFND 1 9,415,118 0 0
The Trade Desk COM CL A 88339J105 1,444,434 24,174,625 SH   DFND 2 17,509,917 0 6,664,708
The Trade Desk COM CL A 88339J105 165,422 2,768,574 SH   DFND 3 2,095,915 0 672,659
The Trade Desk COM CL A 88339J105 494,643 8,278,543 SH   SOLE 0 5,322,211 0 2,956,332
Thermo Fisher Scientific COM 883556102 82,716 163,087 SH   DFND 1 163,087 0 0
Thermo Fisher Scientific COM 883556102 281,971 555,947 SH   DFND 2 508,384 0 47,563
Thermo Fisher Scientific COM 883556102 53,643 105,765 SH   DFND 3 62,754 0 43,011
Thermo Fisher Scientific COM 883556102 260,152 512,928 SH   SOLE 0 342,184 0 170,744
Toro Co COM 891092108 21 245 SH   DFND 3 245 0 0
Tractor Supply Co COM 892356106 29 155 SH   DFND 3 155 0 0
TransMedics Group COM 89377M109 113 2,699 SH   DFND 2 2,699 0 0
TransMedics Group COM 89377M109 1,360 32,572 SH   DFND 3 32,572 0 0
Trip.com Group Sponsored ADR AMERICAN DEP SHS 89677Q107 21,601 790,970 SH   DFND 2 383,087 0 407,883
Trupanion COM 898202106 11,743 197,600 SH   DFND 1 197,600 0 0
Trupanion COM 898202106 16,661 280,346 SH   DFND 2 108,546 0 171,800
Trupanion COM 898202106 8,031 135,136 SH   DFND 3 135,136 0 0
Trupanion COM 898202106 22,651 381,138 SH   SOLE 0 381,138 0 0
TuSimple Hdgs CL A 90089L108 3 349 SH   DFND 3 349 0 0
Twilio Inc CL A 90138F102 135,290 1,956,749 SH   DFND 1 1,956,749 0 0
Twilio Inc CL A 90138F102 231,960 3,354,925 SH   DFND 2 3,216,042 0 138,883
Twilio Inc CL A 90138F102 21,707 313,953 SH   DFND 3 219,814 0 94,139
Twilio Inc CL A 90138F102 89,540 1,295,055 SH   SOLE 0 962,649 0 332,406
Twist Bioscience Corp COM 90184D100 10,322 292,900 SH   DFND 1 292,900 0 0
Twist Bioscience Corp COM 90184D100 7,690 218,216 SH   DFND 2 85,030 0 133,186
Twist Bioscience Corp COM 90184D100 3,765 106,852 SH   DFND 3 106,852 0 0
Twist Bioscience Corp COM 90184D100 9,621 273,000 SH   SOLE 0 273,000 0 0
Ultragenyx COM 90400D108 5 115 SH   DFND 3 115 0 0
United Parcel Service CL B 911312106 68,202 422,198 SH   DFND 1 422,198 0 0
United Parcel Service CL B 911312106 554 3,432 SH   DFND 2 0 0 3,432
United Parcel Service CL B 911312106 10,297 63,741 SH   DFND 3 63,741 0 0
United Parcel Service CL B 911312106 42,034 260,207 SH   SOLE 0 260,207 0 0
UnitedHealth COM 91324P102 34 67 SH   DFND 3 67 0 0
Unity Biotechnology Inc COM 91381U101 98 248,000 SH   DFND 1 248,000 0 0
Unity Biotechnology Inc COM 91381U101 135 341,111 SH   SOLE 0 341,111 0 0
Upwork Inc COM 91688F104 36,051 2,646,937 SH   DFND 1 2,646,937 0 0
Upwork Inc COM 91688F104 23,351 1,714,491 SH   DFND 2 674,329 0 1,040,162
Upwork Inc COM 91688F104 12,053 884,949 SH   DFND 3 800,890 0 84,059
Upwork Inc COM 91688F104 18,277 1,341,907 SH   SOLE 0 1,341,907 0 0
Vale SA ADR ADR 91912E105 9 647 SH   DFND 2 647 0 0
Varonis Systems Inc COM 922280102 46 1,719 SH   DFND 2 1,719 0 0
Varonis Systems Inc COM 922280102 555 20,943 SH   DFND 3 20,943 0 0
Veeco Instruments COM 922417100 4,253 232,154 SH   DFND 1 232,154 0 0
Veeco Instruments COM 922417100 7,745 422,742 SH   DFND 2 169,153 0 253,589
Veeco Instruments COM 922417100 3,892 212,443 SH   DFND 3 212,443 0 0
Veeva Systems Inc Class A COM 922475108 1,164 7,059 SH   DFND 1 7,059 0 0
Veeva Systems Inc Class A COM 922475108 2,522 15,299 SH   DFND 2 15,299 0 0
Veeva Systems Inc Class A COM 922475108 3,141 19,048 SH   DFND 3 19,048 0 0
Verint Systems Inc COM 92343X100 13 395 SH   DFND 3 395 0 0
Veritone COM 92347M100 4 649 SH   DFND 3 649 0 0
Vir Biotechnology Inc COM 92764N102 589 30,548 SH   DFND 1 30,548 0 0
Vir Biotechnology Inc COM 92764N102 1,224 63,492 SH   DFND 2 63,492 0 0
Vir Biotechnology Inc COM 92764N102 1,595 82,709 SH   DFND 3 82,709 0 0
Vir Biotechnology Inc COM 92764N102 73,301 3,801,908 SH   SOLE 0 3,801,908 0 0
Visa Inc-Class A Shares COM CL A 92826C839 9,307 52,389 SH   DFND 2 52,389 0 0
Visa Inc-Class A Shares COM CL A 92826C839 20 110 SH   DFND 3 110 0 0
Visteon Corp COM 92839U206 23 218 SH   DFND 3 218 0 0
Vuzix COM 92921W300 5 924 SH   DFND 3 924 0 0
WD-40 Co COM 929236107 12 67 SH   DFND 3 67 0 0
WEC Energy Group COM 92939U106 1,015 11,353 SH   DFND 1 11,353 0 0
Wal-Mart Stores COM 931142103 13 101 SH   DFND 3 101 0 0
Warby Parker Inc CL A COM 93403J106 2,774 207,983 SH   DFND 1 207,983 0 0
Warby Parker Inc CL A COM 93403J106 7,333 549,730 SH   DFND 2 216,624 0 333,106
Warby Parker Inc CL A COM 93403J106 892 66,900 SH   DFND 3 43,231 0 23,669
Warby Parker Inc CL A COM 93403J106 73,065 5,477,124 SH   SOLE 0 5,477,124 0 0
Waters COM 941848103 8,024 29,772 SH   DFND 1 29,772 0 0
Waters COM 941848103 9,469 35,131 SH   DFND 2 27,464 0 7,667
Waters COM 941848103 2,672 9,914 SH   DFND 3 6,305 0 3,609
Waters COM 941848103 422 1,567 SH   SOLE 0 1,567 0 0
Watsco Inc COM 942622200 223,033 866,282 SH   DFND 1 866,282 0 0
Watsco Inc COM 942622200 243,315 945,061 SH   DFND 2 921,930 0 23,131
Watsco Inc COM 942622200 21,175 82,246 SH   DFND 3 76,188 0 6,058
Watsco Inc COM 942622200 69,909 271,533 SH   SOLE 0 271,533 0 0
Wayfair Inc Class A CL A 94419L101 73,953 2,271,979 SH   DFND 1 2,271,979 0 0
Wayfair Inc Class A CL A 94419L101 117,680 3,615,351 SH   DFND 2 3,421,136 0 194,215
Wayfair Inc Class A CL A 94419L101 11,379 349,577 SH   DFND 3 264,846 0 84,731
Wayfair Inc Class A CL A 94419L101 86,118 2,645,709 SH   SOLE 0 2,364,854 0 280,855
West Pharmaceutical Services COM 955306105 10 40 SH   DFND 3 40 0 0
Wheaton Precious Metals COM 962879102 661 20,416 SH   DFND 1 20,416 0 0
Williams-Sonoma Inc COM 969904101 7 63 SH   DFND 3 63 0 0
Wix Com SHS M98068105 636,263 8,133,234 SH   DFND 2 6,097,223 0 2,036,011
Wix Com SHS M98068105 32 406 SH   DFND 3 406 0 0
Workday Inc CL A 98138H101 197,453 1,297,158 SH   DFND 1 1,297,158 0 0
Workday Inc CL A 98138H101 170,932 1,122,926 SH   SOLE 0 614,309 0 508,617
Workday Inc CL A 98138H101 663,648 4,359,796 SH   DFND 2 2,498,476 0 1,861,320
Workday Inc CL A 98138H101 81,687 536,640 SH   DFND 3 431,217 0 105,423
XP CL A G98239109 169 8,893 SH   DFND 4 8,893 0 0
XP CL A G98239109 1,300 68,387 SH   DFND 1 68,387 0 0
XP CL A G98239109 3,268 171,904 SH   DFND 2 12,129 0 159,775
XP CL A G98239109 4,086 214,952 SH   DFND 3 16,980 0 197,972
XPEL COM 98379L100 21 326 SH   DFND 3 326 0 0
Xencor Inc COM 98401F105 64 2,452 SH   DFND 2 2,452 0 0
Xencor Inc COM 98401F105 769 29,603 SH   DFND 3 29,603 0 0
Xylem COM 98419M100 22,254 254,743 SH   SOLE 0 93,615 0 161,128
Xylem COM 98419M100 96,675 1,106,632 SH   DFND 3 858,052 0 248,580
Xylem COM 98419M100 47,549 544,291 SH   DFND 2 293,677 0 250,614
Xylem COM 98419M100 92,525 1,059,118 SH   DFND 1 1,059,118 0 0
Ziff Davis Inc COM 48123V102 4 53 SH   DFND 3 53 0 0
Zillow Group Inc Class A CL A 98954M101 2,601 90,840 SH   SOLE 0 90,840 0 0
Zillow Group Inc Class A CL A 98954M101 1,716 59,929 SH   DFND 3 59,929 0 0
Zillow Group Inc Class A CL A 98954M101 887 30,990 SH   DFND 1 30,990 0 0
Zillow Group Inc Class A CL A 98954M101 3,845 134,300 SH   DFND 2 52,409 0 81,891
Zillow Group Inc Class C CL C CAP STK 98954M200 16,696 583,573 SH   SOLE 0 583,573 0 0
Zillow Group Inc Class C CL C CAP STK 98954M200 7,045 246,260 SH   DFND 3 246,260 0 0
Zillow Group Inc Class C CL C CAP STK 98954M200 16,655 582,145 SH   DFND 2 223,987 0 358,158
Zillow Group Inc Class C CL C CAP STK 98954M200 27,913 975,649 SH   DFND 1 975,649 0 0
Zoom Video Communications Inc CL A 98980L101 154,221 2,095,683 SH   SOLE 0 1,648,455 0 447,228
Zoom Video Communications Inc CL A 98980L101 109,475 1,487,628 SH   DFND 1 1,487,628 0 0
Zoom Video Communications Inc CL A 98980L101 324,193 4,405,397 SH   DFND 2 2,774,343 0 1,631,054
Zoom Video Communications Inc CL A 98980L101 35,191 478,206 SH   DFND 3 388,649 0 89,557
ZoomInfo Technologies COM 98980F104 16 384 SH   DFND 3 384 0 0
Zuora Inc Class A COM CL A 98983V106 5,767 781,436 SH   SOLE 0 781,436 0 0
Zuora Inc Class A COM CL A 98983V106 14,835 2,010,224 SH   DFND 1 2,010,224 0 0
Zuora Inc Class A COM CL A 98983V106 10,282 1,393,164 SH   DFND 2 545,348 0 847,816
Zuora Inc Class A COM CL A 98983V106 5,169 700,408 SH   DFND 3 700,408 0 0
Zymergen Inc COM 98985X100 7,845 2,821,956 SH   SOLE 0 2,821,956 0 0
Zynex COM 98986M103 4 481 SH   DFND 3 481 0 0
dLocal CL A G29018101 5,054 246,272 SH   DFND 3 0 0 246,272
dLocal CL A G29018101 3 142 SH   DFND 2 142 0 0
dLocal CL A G29018101 11,362 553,728 SH   DFND 1 553,728 0 0
iRobot COM 462726100 6,588 116,959 SH   DFND 3 106,171 0 10,788
iRobot COM 462726100 279 4,955 SH   SOLE 0 4,955 0 0
iRobot COM 462726100 12,553 222,841 SH   DFND 1 222,841 0 0
iRobot COM 462726100 11,663 207,054 SH   DFND 2 80,376 0 126,678
nLIGHT COM 65487K100 4 468 SH   DFND 3 468 0 0