-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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 JHila4xtN3jmTFZhpw2yJw==

<SEC-DOCUMENT>0001181431-10-056043.txt : 20101116
<SEC-HEADER>0001181431-10-056043.hdr.sgml : 20101116
<ACCEPTANCE-DATETIME>20101116190138
ACCESSION NUMBER:		0001181431-10-056043
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20101112
FILED AS OF DATE:		20101116
DATE AS OF CHANGE:		20101116

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Potter Robert Presley
		CENTRAL INDEX KEY:			0001384517

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-26137
		FILM NUMBER:		101197842

	MAIL ADDRESS:	
		STREET 1:		411 108TH AVENUE NE, SUITE 1400
		CITY:			BELLEVUE
		STATE:			WA
		ZIP:			98004

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			DRUGSTORE COM INC
		CENTRAL INDEX KEY:			0001086467
		STANDARD INDUSTRIAL CLASSIFICATION:	RETAIL-DRUG STORES AND PROPRIETARY STORES [5912]
		IRS NUMBER:				043416255
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		411 108TH AVE. NE
		STREET 2:		SUITE 1400
		CITY:			BELLEVUE
		STATE:			WA
		ZIP:			98004
		BUSINESS PHONE:		4253723200

	MAIL ADDRESS:	
		STREET 1:		411 108TH AVE. NE
		STREET 2:		SUITE 1400
		CITY:			BELLEVUE
		STATE:			WA
		ZIP:			98004
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>rrd286391.xml
<DESCRIPTION>RSU 11.12.2010 ANNUAL PERF GRANT
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0303</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2010-11-12</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001086467</issuerCik>
        <issuerName>DRUGSTORE COM INC</issuerName>
        <issuerTradingSymbol>DSCM</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001384517</rptOwnerCik>
            <rptOwnerName>Potter Robert Presley</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O DRUGSTORE.COM, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>411  108TH AVE NE STE 1400</rptOwnerStreet2>
            <rptOwnerCity>BELLEVUE</rptOwnerCity>
            <rptOwnerState>WA</rptOwnerState>
            <rptOwnerZipCode>98004</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>VP, Chief Accounting Officer</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>Restricted Stock Unit Award</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>0.00</value>
                <footnoteId id="F1"/>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2010-11-12</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>45000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <value>2010-10-03</value>
                <footnoteId id="F2"/>
            </exerciseDate>
            <expirationDate>
                <value>2014-10-03</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>45000</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>45000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">Each restricted stock unit represents a contingent right to receive one share of drugstore.com, inc. common stock.</footnote>
        <footnote id="F2">Indicates vesting commencement date; the restricted stock unit (&quot;RSU&quot;) become exercisable as to the RSUs'original share total over 48 months, at the rate of one-eigthth on each six month anniversay of the vesting commencement date until all shares are fully vested, subject to awardee continuing to be a Service Provider.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Robert Presley Potter</signatureName>
        <signatureDate>2010-11-16</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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