The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ALPHABET INC CAP STK CL A 02079K305 89,518 66,835 SH   SOLE   66,835 0 0
BOOKING HLDGS INC COM 09857L108 194,663 94,785 SH   SOLE   94,785 0 0
FACEBOOK INC CL A 30303M102 283,253 1,380,037 SH   SOLE   1,380,037 0 0
FULCRUM THERAPEUTICS INC COM 359616109 6,834 410,714 SH   SOLE   410,714 0 0
INVESCO QQQ TR UNIT SER 1 46090E103 11,425 53,738 SH   SOLE   53,738 0 0
ISHARES TR CORE S&P500 ETF 464287200 22,704 70,238 SH   SOLE   70,238 0 0
ISHARES TR CORE S&P MCP ETF 464287507 5,434 26,403 SH   SOLE   26,403 0 0
ISHARES TR CORE S&P SCP ETF 464287804 5,104 60,873 SH   SOLE   60,873 0 0
MAGENTA THERAPEUTICS INC COM 55910K108 5,042 332,610 SH   SOLE   332,610 0 0
NEON THERAPEUTICS INC COM 64050Y100 597 505,871 SH   SOLE   505,871 0 0
NUCANA PLC SPONSORED ADR 67022C106 17,263 2,911,111 SH   SOLE   2,911,111 0 0
PALO ALTO NETWORKS INC COM 697435105 207,726 898,273 SH   SOLE   898,273 0 0
SPDR GOLD TRUST GOLD SHS 78463V107 14,409 100,835 SH   SOLE   100,835 0 0
UBER TECHNOLOGIES INC COM 90353T100 53,515 1,799,418 SH   SOLE   1,799,418 0 0
VANGUARD GROUP DIV APP ETF 921908844 356 2,858 SH   SOLE   2,858 0 0
VANGUARD INTL EQUITY INDEX F FTSE EMR MKT ETF 922042858 7,702 173,197 SH   SOLE   173,197 0 0
VANGUARD TAX MANAGED INTL FD FTSE DEV MKT ETF 921943858 13,763 312,360 SH   SOLE   312,360 0 0
VANGUARD WORLD FD EXTENDED DUR 921910709 6,144 47,266 SH   SOLE   47,266 0 0