ADOBE INC COM 00724F101 11940 43222 SH SOLE 43222 0 0 ADURO BIOTECH INC COM 00739L101 679 640595 SH SOLE 640595 0 0 ALPHABET INC CAP STK CL A 02079K305 129554 106093 SH SOLE 106093 0 0 BOOKING HLDGS INC COM 09857L108 173881 88597 SH SOLE 88597 0 0 FACEBOOK INC CL A 30303M102 403887 2268011 SH SOLE 2268011 0 0 FULCRUM THERAPEUTICS INC CL A 359616109 2727 410714 SH SOLE 410714 0 0 INVESCO QQQ TR UNIT SER 1 46090E103 9538 50517 SH SOLE 50517 0 0 ISHARES TR CORE S&P500 ETF 464287200 20616 69061 SH SOLE 69061 0 0 ISHARES TR CORE S&P MCP ETF 464287507 5002 25885 SH SOLE 25885 0 0 ISHARES TR CORE S&P SCP ETF 464287804 4552 58484 SH SOLE 58484 0 0 MAGENTA THERAPEUTICS INC COM 55910K108 3413 332610 SH SOLE 332610 0 0 NEON THERAPEUTICS INC COM 64050Y100 870 505871 SH SOLE 505871 0 0 PALO ALTO NETWORKS INC COM 697435105 265104 1300615 SH SOLE 1300615 0 0 SPDR GOLD TRUST GOLD SHS 78463V107 14075 101355 SH SOLE 101355 0 0 VANGUARD GROUP DIV APP ETF 921908844 342 2858 SH SOLE 2858 0 0 VANGUARD INTL EQUITY INDEX F FTSE EMR MKT ETF 922042858 7558 187728 SH SOLE 187728 0 0 VANGUARD TAX MANAGED INTL FD FTSE DEV MKT ETF 921943858 12795 311456 SH SOLE 311456 0 0 VANGUARD WORLD FD EXTENDED DUR 921910709 7269 51442 SH SOLE 51442 0 0