X0508 4 2025-12-22 false 0001082554 UNITED THERAPEUTICS Corp UTHR 0001673232 BENKOWITZ MICHAEL C/O UNITED THERAPEUTICS CORPORATION 1000 SPRING STREET SILVER SPRING MD 20910 false true false false PRESIDENT AND COO true Common Stock 2025-12-22 4 M false 14625.00 117.76 D 14625.00 I by Trust Common Stock 2025-12-22 4 S false 682.00 512.1382 D 13943.00 I by Trust Common Stock 2025-12-22 4 S false 848.00 513.3992 D 13095.00 I by Trust Common Stock 2025-12-22 4 S false 11815.00 514.3067 D 1280.00 I by Trust Common Stock 2025-12-22 4 S false 440.00 515.5326 D 840.00 I by Trust Common Stock 2025-12-22 4 S false 560.00 516.3671 D 280.00 I by Trust Common Stock 2025-12-22 4 S false 200.00 517.7381 D 80.00 I by Trust Common Stock 2025-12-22 4 S false 80.00 518.91 D 0.00 I by Trust Common Stock 2025-12-22 4 M false 6190.00 146.03 A 6190.00 I by Trust Common Stock 2025-12-22 4 M false 1685.00 146.03 A 7875.00 I by Trust Common Stock 2025-12-22 4 S false 120.00 511.6735 D 7755.00 I by Trust Common Stock 2025-12-22 4 S false 360.00 512.5667 D 7395.00 I by Trust Common Stock 2025-12-22 4 S false 6635.00 514.2769 D 760.00 I by Trust Common Stock 2025-12-22 4 S false 200.00 515.244 D 560.00 I by Trust Common Stock 2025-12-22 4 S false 360.00 516.3589 D 200.00 I by Trust Common Stock 2025-12-22 4 S false 120.00 517.66 D 80.00 I by Trust Common Stock 2025-12-22 4 S false 80.00 518.985 D 0.00 I by Trust Common Stock 2648.00 D Stock Options 146.03 2025-12-22 4 M false 6190.00 0.00 D 2020-03-15 2027-03-15 Common Stock 6190.00 0.00 I by Trust Stock Options 146.03 2025-12-22 4 M false 1685.00 0.00 D 2020-03-15 2027-03-15 Common Stock 1685.00 68065.00 I by Trust Stock Options 117.76 2025-12-22 4 M false 14625.00 0.00 D 2020-03-15 2027-03-15 Common Stock 14625.00 126375.00 I by Trust This exercise of stock options and subsequent sale of shares was pursuant to a Rule 10b5-1 trading plan entered into by the reporting person on June 3, 2025. Reflects the exercise of options, and sale of the resulting shares of common stock, held in a trust beneficially owned by the Reporting Person, of which the Reporting Person's family members are beneficiaries, and as to which the Reporting Person has sole investment and voting power. This transaction was executed in multiple trades at prices ranging from $511.13 to $511.99. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $512.13 to $512.96. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $513.43 to $514.33. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $514.65 to $515.63. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $515.72 to $516.55. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $518.98 to $518.99. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. Reflects the exercise of options, and sale of the resulting shares of common stock, held in a trust beneficially owned by the Reporting Person, of which the Reporting Person is a beneficiary, and as to which the Reporting Person and his spouse are co-trustees and have shared investment and voting power. This transaction was executed in multiple trades at prices ranging from $511.66 to $512.56. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $512.81 to $513.79. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $513.83 to $514.60. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $514.93 to $515.88. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $516.02 to $517.01. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $517.26 to $517.93. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $518.80 to $519.02. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. /s/ John S. Hess, Jr. under Power of Attorney 2025-12-29