X0508 4 2025-09-29 false 0001082554 UNITED THERAPEUTICS Corp UTHR 0001673232 BENKOWITZ MICHAEL C/O UNITED THERAPEUTICS CORPORATION 1000 SPRING STREET SILVER SPRING MD 20910 false true false false PRESIDENT AND COO true Common Stock 2025-09-29 4 M false 14625.00 135.42 A 14625.00 I by Trust Common Stock 2025-09-29 4 S false 650.00 416.596 D 13975.00 I by Trust Common Stock 2025-09-29 4 S false 1235.00 417.5184 D 12740.00 I by Trust Common Stock 2025-09-29 4 S false 690.00 418.7976 D 12050.00 I by Trust Common Stock 2025-09-29 4 S false 1327.00 419.7706 D 10723.00 I by Trust Common Stock 2025-09-29 4 S false 1971.00 420.9437 D 8752.00 I by Trust Common Stock 2025-09-29 4 S false 2659.00 421.7504 D 6093.00 I by Trust Common Stock 2025-09-29 4 S false 2073.00 422.7166 D 4020.00 I by Trust Common Stock 2025-09-29 4 S false 2206.00 423.9287 D 1814.00 I by Trust Common Stock 2025-09-29 4 S false 674.00 424.8005 D 1140.00 I by Trust Common Stock 2025-09-29 4 S false 490.00 425.8409 D 650.00 I by Trust Common Stock 2025-09-29 4 S false 489.00 428.6366 D 161.00 I by Trust Common Stock 2025-09-29 4 S false 96.00 429.5042 D 65.00 I by Trust Common Stock 2025-09-29 4 S false 65.00 430.7482 D 0.00 I by Trust Common Stock 2025-09-29 4 M false 7875.00 146.03 A 7875.00 I by Trust Common Stock 2025-09-29 4 S false 350.00 416.596 D 7525.00 I by Trust Common Stock 2025-09-29 4 S false 665.00 417.5184 D 6860.00 I by Trust Common Stock 2025-09-29 4 S false 371.00 418.797 D 6489.00 I by Trust Common Stock 2025-09-29 4 S false 715.00 419.7708 D 5774.00 I by Trust Common Stock 2025-09-29 4 S false 1062.00 420.944 D 4712.00 I by Trust Common Stock 2025-09-29 4 S false 1432.00 421.7509 D 3280.00 I by Trust Common Stock 2025-09-29 4 S false 1116.00 422.7169 D 2164.00 I by Trust Common Stock 2025-09-29 4 S false 1187.00 423.9286 D 977.00 I by Trust Common Stock 2025-09-29 4 S false 363.00 424.8004 D 614.00 I by Trust Common Stock 2025-09-29 4 S false 264.00 425.8408 D 360.00 I by Trust Common Stock 2025-09-29 4 S false 264.00 428.6373 D 96.00 I by Trust Common Stock 2025-09-29 4 S false 51.00 429.5033 D 35.00 I by Trust Common Stock 2025-09-29 4 S false 35.00 430.7477 D 0.00 I by Trust Common Stock 2648.00 D Stock Options 135.42 2025-09-29 4 M false 14625.00 0.00 D 2023-03-15 2027-03-15 Common Stock 14625.00 114375.00 I by Trust Stock Options 146.03 2025-09-29 4 M false 7875.00 0.00 D 2018-03-15 2027-03-15 Common Stock 7875.00 25375.00 I by Trust This exercise of stock options and subsequent sale of shares was pursuant to a Rule 10b5-1 trading plan entered into by the reporting person on June 3, 2025. This transaction was executed in multiple trades at prices ranging from $423.42 to $424.40. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $424.42 to $425.19. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $425.73 to $426.37. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $428.34 to $429.17. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $429.45 to $429.61. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $430.60 to $430.86. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. Reflects the exercise of options, and sale of the resulting shares of common stock, held in a trust beneficially owned by the Reporting Person, of which the Reporting Person's family members are beneficiaries, and as to which the Reporting Person has sole investment and voting power. This transaction was executed in multiple trades at prices ranging from $417.08 to $418.07. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $418.15 to $419.10. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $419.32 to $420.31. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. Reflects the exercise of options, and sale of the resulting shares of common stock, held in a trust beneficially owned by the Reporting Person, of which the Reporting Person is a beneficiary, and as to which the Reporting Person and his spouse are co-trustees and have shared investment and voting power. This transaction was executed in multiple trades at prices ranging from $420.32 to $421.31. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $421.32 to $422.28. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $422.33 to $423.24. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $423.42 to $424.40. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $424.42 to $425.19. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $425.73 to $426.37. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $428.34 to $429.17. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $429.45 to $429.61. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $430.60 to $430.86. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $416.02 to $416.91. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $417.08 to $418.07. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $418.15 to $419.10. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $419.32 to $420.31. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $420.32 to $421.31. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $421.32 to $422.28. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $422.33 to $423.24. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. /s/ John S. Hess, Jr. under Power of Attorney 2025-10-01